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Table 1:

Major clinical characteristics and tumor histology in various pLGG subgroups

BRAF V600E-Mut (n = 11)BRAF-KIAA Rearrangement (n = 20)Wild-Type BRAF (n = 8)NF1 (n = 12)P Value
Sex (male/female)8/37/135/37/5.45
Age at diagnosis (mean) (yr)9.1 (SD, 4.7)5.4 (SD, 3.9)14.6 (SD, 8.7)4.9 (SD, 2.9).03
Histology (No.)
 PA7197
 GG211a
 PXA2
 Diffuse astrocytoma (grade II)1
  • Note:—PA indicates pilocytic astrocytoma; PXA, pleomorphic xanthoastrocytoma; Mut, mutant.

  • a In 1 patient with NF1, a ganglioglioma was found at biopsy.