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Table 3: Relative mean metabolite concentrations and calculated ratios in DN/pons in all 4 studied groups
Variable Studied Groups Comparisons (P Values)
Case Control 1 Control 2 Control 3 Among 4 Groups Case vs. Control 3 Case vs Controls 1 and 2
NAA 0.7 (SD, 0.1) 1.1 (SD, 0.3) 0.8 (SD, 0.2) 0.9 (SD, 0.5) .13 .38 .36
Choline 0.8 (SD, 0.3) 0.8 (SD, 0.4) 0.9 (SD, 0.3) 0.8 (SD, 0.4) .98 .97 .70
Cr on short TE 1.4 (SD, 0.5) 1.1 (SD, 0.6) 1.0 (SD, 0.2) 1.8 (SD, 2.5) .54 .61 .03^{^a}
Lactate on short TE 4.3 (SD, 7.4) 1.5 (SD, 2.0) 1.0 (SD, 1.6) 0.2 (SD, 0.4) .32 .25 .26
mIns 0.9 (SD, 0.5) 0.5 (SD, 0.4) 1.3 (SD, 1.5) 1.1 (SD, 1.2) .35 .69 .42
Glx 1.2 (SD, 0.8) 1.0 (SD, 0.6) 1.3 (SD, 1.0) 1.3 (SD, 0.6) .84 .72 .81
Lipid 0.9 1.3 (SD, 0.8) 1.1 (SD, 0.7) 0.8 (SD, 0.5) 1.3 (SD, 1.0) .43 .96 .13
Lipid 1.3 1.4 (SD, 1.0) 1.0 (SD, 1.3) 1.4 (SD, 1.0) 1.0 (SD, 0.5) .74 .33 .93
NAA/Cr 0.7 (SD, 0.2) 0.8 (SD, 0.4) 0.6 (SD, 0.3) 0.9 (SD, 0.5) .29 .44 .15
Lactate/Cr on short TE 0.2 (SD, 0.1) 0.2 (SD, 0.1) 0.1 (SD, 0.1) 0.2 (SD, 0.1) .95 .56 .61
mIns/Cr 0.6 (SD, 0.3) 0.4 (SD, 0.2) 1.3 (SD, 1.5) 0.7 (SD, 0.5) .11 .56 .20
Glx/Cr 1.1 (SD, 0.6) 0.9 (SD, 0.6) 1.5 (SD, 1.5) 1.2 (SD, 0.8) .67 .58 .48
Lipid 0.9/Cr 1.0 (SD, 0.6) 1.0 (SD, 0.5) 0.8 (SD, 0.4) 1.0 (SD, 0.7) .68 .83 .33
Lipid 1.3/Cr 1.5 (SD, 0.6) 1.3 (SD, 0.6) 1.8 (SD, 1.0) 0.8 (SD, 0.5) .17 .04^{^a} .45
↵a Statistically significant.