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Table 2: Multivariable linear mixed-effects modeling of CBF based on clinical, demographic, and study factors^{^a}
Mod_Baseline Mod_HCP Mod_HCPCMS
(Intercept) 43.3 (3.86)^{^b} 48.4 (4.06)^{^b} 50.1 (4.70)^{^b}
Postop time point 6.21 (2.00)^{^c} 3.01 (2.08) 1.55 (2.20)
Follow-up time point 14.8 (2.07)^{^b} 10.5 (2.15)^{^b} 7.74 (2.31)^{^b}
Age −0.686 (0.45) −1.17 (0.53)^{^d} −1.34 (0.59)^{^d}
Thalamus −5.55 (1.60)^{^b} −5.59 (1.51)^{^b} −5.60 (1.45)^{^b}
Cerebellum −10.0 (1.59)^{^b} −10.0 (1.50)^{^b} –10.0 (1.44)^{^b}
Unsedated (vs GA) – 3.57 (3.79) 5.73 (3.93)
Hydrocephalus – −19.4 (6.04)^{^c} −20.5 (6.27)^{^c}
Postop time point + HCP – 21.5 (5.17)^{^b} 24.0 (5.13)^{^b}
Follow-up time point + HCP – 26.0 (5.22)^{^b} 27.2 (5.18)^{^b}
CMS – – −10.9 (6.46)^{^e}
Postop time point + CMS – – 8.74 (5.26)^{^e}
Follow-up time point + CMS – – 15.6 (5.28)^{^c}
AIC 1841.5 1824.7 1821.8
Marginal R² 0.224 0.290 0.295
Conditional R² 0.607 0.650 0.692
Note:—– indicates not included in model; GA, general anesthesia; Post-op, postoperative.
↵a Values are coefficients (standard error).
↵b P < .001.
↵c P < .01.
↵d P < .05.
↵e P < .1.