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Table 2: Absolute mean metabolite concentrations and calculated ratios in the DN in all 4 studied groups
Variable Studied Groups Comparisons (P Values)
Case Control 1 Control 2 Control 3 Among 4 Groups Case vs Control 3 Case vs. Controls 1 and 2
NAA 43.0 (SD, 7.3) 44.8 (SD, 11.7) 45.3 (SD, 10.5) 36.7 (SD, 10.8) .24 .15 .59
Choline 32.8 (SD, 9.7) 25.7 (SD, 11.5) 28.8 (SD, 5.8) 23.5 (SD, 11.8) .20 .07 .27
Cr on short TE 11.6 (SD, 1.3) 9.3 (SD, 4.3) 10.1 (SD, 1.8) 8.9 (SD, 3.3) .21 .04^{^a} .06
Lactate on short TE 4.6 (SD, 2.2) 2.3 (SD, 2.1) 2.1 (SD, 1.3) 3.2 (SD, 2.8) .15 .33 .02^{^a}
mIns 2.7 (SD, 0.7) 1.5 (SD, 0.8) 2.4 (SD, 1.2) 1.7 (SD, 1.2) .04^{^a} .04^{^a} .51
Glx 3.5 (SD, 1.7) 3.7 (SD, 1.7) 4.9 (SD, 1.8) 4.5 (SD, 2.7) .36 .35 .10
Lipid 0.9 4.8 (SD, 2.0) 3.9 (SD, 2.4) 4.1 (SD, 1.8) 3.5 (SD, 2.2) .65 .22 .44
Lipid 1.3 5.2 (SD, 2.7) 5.8 (SD, 4.1) 6.5 (SD, 3.6) 5.7 (SD, 3.0) .92 .73 .42
NAA/Cr 1.7 (SD, 0.5) 2.1 (SD, 0.9) 1.6 (SD, 0.6) 2.8 (SD, 2.0) .10 .11 .73
Lactate/Cr on short TE 0.4 (SD, 0.2) 0.3 (SD, 0.2) 0.2 (SD, 0.2) 0.3 (SD, 0.2) .25 .50 .04^{^a}
mIns/Cr 0.2 (SD, 0.1) 0.2 (SD, 0.2) 0.2 (SD, 0.1) 0.2 (SD, 0.1) .68 .16 .99
Glx/Cr 0.3 (SD, 0.1) 0.5 (SD, 0.3) 0.5 (SD, 0.2) 0.5 (SD, 0.3) .35 .08 .04^{^a}
Lipid 0.9/Cr 0.4 (SD, 0.3) 0.4 (SD, 0.2) 0.4 (SD, 0.1) 0.4 (SD, 0.1) .91 .50 .76
Lipid 1.3/Cr 0.4 (SD, 0.2) 0.9 (SD, 1.0) 0.6 (SD, 0.4) 0.8 (SD, 0.4) .43 .05 .19
↵a Statistically significant.