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Table 1: Clinical overview of the included patients with pathology-confirmed DLBC EBV-positive CNS lymphoma
  Age (yr) Sex Underlying Conditions Radiologic Diagnosis^{^a} Diagnostic-Therapeutic Initial Management
P 1 66 Male Kidney transplant Multiple metastases^{^b} Biopsy: reason, multiple lesions
P 2 76 Male Chronic myeloproliferative disorder; essential thrombocythemia Glioblastoma Biopsy: reason, patient basal clinical status
P 3 74 Male Liver transplant Single metastasis^{^c} Biopsy: reason, second-look radiologic opinion
P 4 62 Female Systemic sclerosis and discoid cutaneous lupus Glioblastoma Maximal safe surgical resection
P 5 70 Female Immunosenescence Multiple metastases or multifocal glioblastoma Biopsy: reason, multiple lesions
P 6 63 Male Autoimmune hepatitis Metastasis or glioblastoma Maximal safe surgical resection
P 7 78 Female Kidney transplant Single metastasis Maximal safe surgical resection
Note:—P indicates patient.
↵a Based on a radiologic report from our neuro-oncology reference tertiary university hospital.
↵b Atypical infection was considered, but as an unlikely option.
↵c A second-look opinion raised the possibility of atypical lymphoma.