1naresh
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Advantage Disadvantage Width Simple, practical, good external applicability, sensitivity easy to adjust (2 vs 5 mm, and so forth) Too dependent on measurement technique and location, sensitivity might be low Volume Intuitively the right choice, presumably most accurate Labor intensive, unlikely to be used in day-to-day practice Volume + width Raises the bar for specificity More challenging to interpret, 2 thresholds to define Less sensitive Volume + width + MLS Raises the bar for specificity even further Even more challenging to interpret, definition issues, 2 df (>2 mm and > 2 mm and > 20 mL) Low sensitivity