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<meta name="DC.Title" content="Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions" />
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<meta name="DC.Description" content="SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.

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&lt;p&gt;Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T (&lt;i&gt;P&lt;/i&gt; ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.&lt;/p&gt;" />
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<meta name="twitter:title" content="Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions" />
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<meta name="twitter:description" content="SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.

AUC
:   area under the curve
CNR
:   contrast-to-noise ratio
DCE
:   dynamic contrast-enhanced
K trans
:   volume transfer constant
v e
:   extravascular extracellular volume fraction
v p
:   blood plasma fraction" />
<meta name="og-title" property="og:title" content="Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions" />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.

AUC
:   area under the curve
CNR
:   contrast-to-noise ratio
DCE
:   dynamic contrast-enhanced
K trans
:   volume transfer constant
v e
:   extravascular extracellular volume fraction
v p
:   blood plasma fraction" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node39--5" data-node-nid="39" id="top-node-39--6430644576" data-pisa="ajnr;38/1/192" data-pisa-master="ajnr;ajnr.A4995" data-apath="/ajnr/38/1/192.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
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      <h1 class="highwire-cite-title" id="page-title">Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">V. Cuvinciuc</span>, <span class="highwire-citation-author" data-delta="1">M. Viallon</span>, <span class="highwire-citation-author" data-delta="2">I. Barnaure</span>, <span class="highwire-citation-author" data-delta="3">M.I. Vargas</span>, <span class="highwire-citation-author" data-delta="4">K.-O. Lovblad</span> and <span class="highwire-citation-author" data-delta="5">S. Haller</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">January 2017,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">192-194; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A4995 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-39--6430644576" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">V. Cuvinciuc </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (V.C., I.B., M.I.V., K.-O.L., S.H.)</div><div class='author-affiliation'><span class='nlm-sup'>c</span>Centre d'Imagerie Rive Droite (V.C.), Geneva, Switzerland</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=V.%2BCuvinciuc%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Cuvinciuc%20V&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AV.%2BCuvinciuc%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-0596-4047" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for V. Cuvinciuc</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">M. Viallon </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Radiology (M.V.), Geneva University Hospitals, Geneva, Switzerland</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Université de Lyon, INSA de Lyon, Université Jean-Monnet, CHU de Saint-Etienne, CREATIS CNRS 5220, INSERM 1206, F-42055, Saint-Etienne, France (M.V.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BViallon%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Viallon%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BViallon%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0001-9118-0438" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Viallon</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">I. Barnaure </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (V.C., I.B., M.I.V., K.-O.L., S.H.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=I.%2BBarnaure%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Barnaure%20I&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AI.%2BBarnaure%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-4052-4899" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for I. Barnaure</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">M.I. Vargas </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (V.C., I.B., M.I.V., K.-O.L., S.H.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.I.%2BVargas%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Vargas%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.I.%2BVargas%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-6571-5336" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M.I. Vargas</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">K.-O. Lovblad </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (V.C., I.B., M.I.V., K.-O.L., S.H.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=K.-O.%2BLovblad%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lovblad%20K&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AK.-O.%2BLovblad%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-2768-9779" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for K.-O. Lovblad</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">S. Haller </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (V.C., I.B., M.I.V., K.-O.L., S.H.)</div><div class='author-affiliation'><span class='nlm-sup'>e</span>Affidea Centre de Diagnostique Radiologique de Carouge (S.H.), Geneva, Switzerland.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BHaller%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Haller%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BHaller%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0001-7433-0203" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. Haller</a></li></ul></div></div></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 38</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 1 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jan 2017 </div></div>
      
      
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      <div class="highwire-cite-title">Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Cuvinciuc</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Viallon</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Barnaure</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">M.I.</span> <span class="nlm-surname">Vargas</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">K.-O.</span> <span class="nlm-surname">Lovblad</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Haller</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2017, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">192-194; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A4995 </span></div>
  
  
  
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      <div class="highwire-cite-title">Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Cuvinciuc</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Viallon</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Barnaure</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">M.I.</span> <span class="nlm-surname">Vargas</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">K.-O.</span> <span class="nlm-surname">Lovblad</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Haller</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2017, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">192-194; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A4995 </span></div>
  
  
  
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