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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Medina-Rodríguez Manuel</span> and <span class="highwire-citation-author" data-delta="1">Moniche Francisco</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">July 2024,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E21; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A8341 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-108569--6300013468" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Medina-Rodríguez Manuel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Stroke Unit, Department of NeurologyUniversity Hospital Virgen del RocioSeville, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Medina-Rodr%C3%ADguez%2BManuel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Manuel%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMedina-Rodr%25C3%25ADguez%2BManuel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Moniche Francisco </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Institute of Biomedicine of SevilleIBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSeville, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Moniche%2BFrancisco%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Francisco%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMoniche%2BFrancisco%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div></div></div>  </div>

  
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Regarding the antiplatelet regimen used in our cohort, we followed our local protocol, which is in line with the European Vascular Surgery Society Guidelines that recommend dual antiplatelet therapy during at least 4–6 weeks after extracranial CAS.<sup><a id="xref-ref-1-1" class="xref-bibr" href="#ref-1">1</a></sup> In addition, before switching clopidogrel to aspirin, we assessed the stent patency using carotid Doppler ultrasound (US) at 30 days from CAS.</p><p id="p-2">Related to carotid surveillance after CAS, as mentioned, carotid US accurately defined residual stenosis of ≥20%, in-stent restenosis of ≥50%, and high-grade in-stent restenosis in patients with extracranial CAS.<sup><a id="xref-ref-2-1" class="xref-bibr" href="#ref-2">2</a></sup> The velocity peak systolic threshold we established to define in-stent restenosis was ≥300 cm/s in restenosis of ≥70%, as previously described.<sup><a id="xref-ref-2-2" class="xref-bibr" href="#ref-2">2</a></sup> Finally, the reason we focused on the first month of follow-up exclusively was to assess the rate of in-stent thrombosis rather than long-term restenosis. Therefore, we monitored the patency of the stent immediately after CAS and during the first month. This first month is also when the bleeding risk increases related to dual antiplatelet therapy to prevent in-stent thrombosis and oral anticoagulation to prevent systemic embolisms/stroke. Nevertheless, we agree that further information regarding stent patency at 6 months or 1 year would be interesting and would have enriched the work. We thank you for your comments, which we will take into consideration for coming investigations.</p><div class="section ref-list" id="ref-list-1"><h2 class="">References</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1. in text" id="ref-1">↵</a><div class="cit ref-cit ref-journal" id="cit-45.7.E21.1" data-doi="10.1016/j.ejvs.2022.04.011"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Naylor</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Rantner</span>  <span class="cit-name-given-names">B</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ancetti</span>  <span class="cit-name-given-names">S</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Editor’s Choice: European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease</span>. <abbr class="cit-jnl-abbrev">Eur J Vasc Endovasc Surg</abbr> <span class="cit-pub-date">2023</span>;<span class="cit-vol">65</span>:<span class="cit-fpage">7</span>–<span class="cit-lpage">111</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/j.ejvs.2022.04.011</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>35598721</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.ejvs.2022.04.011&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=35598721&amp;link_type=MED&amp;atom=%2Fajnr%2F45%2F7%2FE21.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">2.</span><a class="rev-xref-ref" href="#xref-ref-2-1" title="View reference 2. in text" id="ref-2">↵</a><div class="cit ref-cit ref-journal" id="cit-45.7.E21.2" data-doi="10.1016/j.jvs.2007.09.038"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Lal</span>  <span class="cit-name-given-names">BK</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Hobson</span>  <span class="cit-name-given-names">RW</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Tofighi</span>  <span class="cit-name-given-names">B</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Duplex ultrasound velocity criteria for the stented carotid artery</span>. <abbr class="cit-jnl-abbrev">J Vasc Surg</abbr> <span class="cit-pub-date">2008</span>;<span class="cit-vol">47</span>:<span class="cit-fpage">63</span>–<span class="cit-lpage">73</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/j.jvs.2007.09.038</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>18178455</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.jvs.2007.09.038&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=18178455&amp;link_type=MED&amp;atom=%2Fajnr%2F45%2F7%2FE21.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li></ol></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2024 by American Journal of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 45</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 7 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jul 2024 </div></div>
      
      
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