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<meta name="DC.Title" content="Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy" />
<meta name="DC.Identifier" content="10.3174/ajnr.A8356" />
<meta name="DC.Date" content="2024-10-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2024 by American Journal of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Quantitative susceptibility mapping has been proposed to assess intraplaque hemorrhage (IPH) in the carotid artery. The purpose of this study was to compare the diagnostic accuracy of preoperative quantitative susceptibility mapping with that of the conventional T1-weighed 3D-FSE sequence for detecting IPH in cervical ICA stenosis in patients undergoing carotid endarterectomy by using histology as the reference standard.

MATERIALS AND METHODS: Carotid T1-weighted 3D-FSE and QSM images were obtained from 16 patients with cervical ICA stenosis before carotid endarterectomy. Relative signal intensity and susceptibility of the ICA were measured on 3 axial images, including the location of most severe stenosis on T1-weighted 3D-FSE and quantitative susceptibility mapping images, respectively. Three transverse sections of carotid plaques excised by carotid endarterectomy, which corresponded with images on MR imaging, were stained with H&amp;E, antibody against glycophorin A, and Prussian blue, and the relative area of histologic IPH was calculated.

RESULTS: The correlation coefficient was significantly greater between susceptibility and relative area-histologic IPH ( ρ = 0.691) than between relative signal intensity and relative area-histologic IPH ( ρ = 0.413; P = .0259). The areas under the receiver operating characteristic curves for detecting histologic sections consisting primarily of IPH (relative area-histologic IPH &gt; 40.7%) tended to be greater for susceptibility (0.964) than for T1WI FSE-relative signal intensity (0.811). Marginal homogeneity was observed between susceptibility and histologic sections consisting primarily of IPH ( P = .0412), but not between T1-weighted FSE-relative signal intensity and histologic sections consisting primarily of IPH ( P = .1824).

CONCLUSIONS: Pre-carotid endarterectomy quantitative susceptibility mapping detects histologic IPH in cervical ICA stenosis more accurately than preoperative T1-weighted 3D-FSE imaging.

CEA
:   carotid endarterectomy
IPH
:   intraplaque hemorrhage
QSM
:   quantitative susceptibility mapping
RA
:   relative area
ROC
:   receiver operating characteristic
RSI
:   relative signal intensity" />
<meta name="DC.Contributor" content="Daisuke Oomori" />
<meta name="DC.Contributor" content="Yosuke Akamatsu" />
<meta name="DC.Contributor" content="Ikuko Uwano" />
<meta name="DC.Contributor" content="Futoshi Mori" />
<meta name="DC.Contributor" content="Tsuyoshi Matsuda" />
<meta name="DC.Contributor" content="Ryo Sugimoto" />
<meta name="DC.Contributor" content="Michiko Suzuki" />
<meta name="DC.Contributor" content="Shunrou Fujiwara" />
<meta name="DC.Contributor" content="Masakazu Kobayashi" />
<meta name="DC.Contributor" content="Makoto Sasaki" />
<meta name="DC.Contributor" content="Kunihiro Yoshioka" />
<meta name="DC.Contributor" content="Naoki Yanagawa" />
<meta name="DC.Contributor" content="Kuniaki Ogasawara" />
<meta name="article:published_time" content="2024-10-01" />
<meta name="article:section" content="Neurovascular/Stroke Imaging" />
<meta name="citation_title" content="Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Quantitative susceptibility mapping has been proposed to assess intraplaque hemorrhage (IPH) in the carotid artery. The purpose of this study was to compare the diagnostic accuracy of preoperative quantitative susceptibility mapping with that of the conventional T1-weighed 3D-FSE sequence for detecting IPH in cervical ICA stenosis in patients undergoing carotid endarterectomy by using histology as the reference standard.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Carotid T1-weighted 3D-FSE and QSM images were obtained from 16 patients with cervical ICA stenosis before carotid endarterectomy. Relative signal intensity and susceptibility of the ICA were measured on 3 axial images, including the location of most severe stenosis on T1-weighted 3D-FSE and quantitative susceptibility mapping images, respectively. Three transverse sections of carotid plaques excised by carotid endarterectomy, which corresponded with images on MR imaging, were stained with H&amp;amp;E, antibody against glycophorin A, and Prussian blue, and the relative area of histologic IPH was calculated.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;The correlation coefficient was significantly greater between susceptibility and relative area-histologic IPH (&lt;i&gt;ρ&lt;/i&gt; = 0.691) than between relative signal intensity and relative area-histologic IPH (&lt;i&gt;ρ&lt;/i&gt; = 0.413; &lt;i&gt;P&lt;/i&gt; = .0259). The areas under the receiver operating characteristic curves for detecting histologic sections consisting primarily of IPH (relative area-histologic IPH &amp;gt; 40.7%) tended to be greater for susceptibility (0.964) than for T1WI FSE-relative signal intensity (0.811). Marginal homogeneity was observed between susceptibility and histologic sections consisting primarily of IPH (&lt;i&gt;P&lt;/i&gt; = .0412), but not between T1-weighted FSE-relative signal intensity and histologic sections consisting primarily of IPH (&lt;i&gt;P&lt;/i&gt; = .1824).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Pre-carotid endarterectomy quantitative susceptibility mapping detects histologic IPH in cervical ICA stenosis more accurately than preoperative T1-weighted 3D-FSE imaging.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="2024/10/01" />
<meta name="citation_mjid" content="ajnr;45/10/1461" />
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<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
<meta name="citation_doi" content="10.3174/ajnr.A8356" />
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<meta name="citation_firstpage" content="1461" />
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<meta name="citation_author" content="Daisuke Oomori" />
<meta name="citation_author_institution" content="aFrom the Department of Neurosurgery (D.O., Y.A., S.F., M.K., K.O.), Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author" content="Yosuke Akamatsu" />
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<meta name="citation_author" content="Ikuko Uwano" />
<meta name="citation_author_institution" content="dDivision of Ultrahigh Field MRI (I.U., F.M., T.M., M. Suzuki), Institute for Biomedical Sciences, Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
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<meta name="citation_author" content="Futoshi Mori" />
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<meta name="citation_author" content="Tsuyoshi Matsuda" />
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<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-8914-8236" />
<meta name="citation_author" content="Ryo Sugimoto" />
<meta name="citation_author_institution" content="bDepartment of Molecular Diagnostic Pathology (R.S., N.Y.), Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author" content="Michiko Suzuki" />
<meta name="citation_author_institution" content="cDepartment of Radiology (M.S, K.Y), Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author" content="Shunrou Fujiwara" />
<meta name="citation_author_institution" content="aFrom the Department of Neurosurgery (D.O., Y.A., S.F., M.K., K.O.), Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-5800-515X" />
<meta name="citation_author" content="Masakazu Kobayashi" />
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<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-8205-3090" />
<meta name="citation_author" content="Makoto Sasaki" />
<meta name="citation_author_institution" content="dDivision of Ultrahigh Field MRI (I.U., F.M., T.M., M. Suzuki), Institute for Biomedical Sciences, Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-3108-4361" />
<meta name="citation_author" content="Kunihiro Yoshioka" />
<meta name="citation_author_institution" content="cDepartment of Radiology (M.S, K.Y), Iwate Medical University School of Medicine, Yahaba-cho, Japan" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-0100-042X" />
<meta name="citation_author" content="Naoki Yanagawa" />
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<meta name="citation_author" content="Kuniaki Ogasawara" />
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<meta name="twitter:title" content="Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Quantitative susceptibility mapping has been proposed to assess intraplaque hemorrhage (IPH) in the carotid artery. The purpose of this study was to compare the diagnostic accuracy of preoperative quantitative susceptibility mapping with that of the conventional T1-weighed 3D-FSE sequence for detecting IPH in cervical ICA stenosis in patients undergoing carotid endarterectomy by using histology as the reference standard.

MATERIALS AND METHODS: Carotid T1-weighted 3D-FSE and QSM images were obtained from 16 patients with cervical ICA stenosis before carotid endarterectomy. Relative signal intensity and susceptibility of the ICA were measured on 3 axial images, including the location of most severe stenosis on T1-weighted 3D-FSE and quantitative susceptibility mapping images, respectively. Three transverse sections of carotid plaques excised by carotid endarterectomy, which corresponded with images on MR imaging, were stained with H&amp;E, antibody against glycophorin A, and Prussian blue, and the relative area of histologic IPH was calculated.

RESULTS: The correlation coefficient was significantly greater between susceptibility and relative area-histologic IPH ( ρ = 0.691) than between relative signal intensity and relative area-histologic IPH ( ρ = 0.413; P = .0259). The areas under the receiver operating characteristic curves for detecting histologic sections consisting primarily of IPH (relative area-histologic IPH &gt; 40.7%) tended to be greater for susceptibility (0.964) than for T1WI FSE-relative signal intensity (0.811). Marginal homogeneity was observed between susceptibility and histologic sections consisting primarily of IPH ( P = .0412), but not between T1-weighted FSE-relative signal intensity and histologic sections consisting primarily of IPH ( P = .1824).

CONCLUSIONS: Pre-carotid endarterectomy quantitative susceptibility mapping detects histologic IPH in cervical ICA stenosis more accurately than preoperative T1-weighted 3D-FSE imaging.

CEA
:   carotid endarterectomy
IPH
:   intraplaque hemorrhage
QSM
:   quantitative susceptibility mapping
RA
:   relative area
ROC
:   receiver operating characteristic
RSI
:   relative signal intensity" />
<meta name="og-title" property="og:title" content="Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/45/10/1461" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Quantitative susceptibility mapping has been proposed to assess intraplaque hemorrhage (IPH) in the carotid artery. The purpose of this study was to compare the diagnostic accuracy of preoperative quantitative susceptibility mapping with that of the conventional T1-weighed 3D-FSE sequence for detecting IPH in cervical ICA stenosis in patients undergoing carotid endarterectomy by using histology as the reference standard.

MATERIALS AND METHODS: Carotid T1-weighted 3D-FSE and QSM images were obtained from 16 patients with cervical ICA stenosis before carotid endarterectomy. Relative signal intensity and susceptibility of the ICA were measured on 3 axial images, including the location of most severe stenosis on T1-weighted 3D-FSE and quantitative susceptibility mapping images, respectively. Three transverse sections of carotid plaques excised by carotid endarterectomy, which corresponded with images on MR imaging, were stained with H&amp;E, antibody against glycophorin A, and Prussian blue, and the relative area of histologic IPH was calculated.

RESULTS: The correlation coefficient was significantly greater between susceptibility and relative area-histologic IPH ( ρ = 0.691) than between relative signal intensity and relative area-histologic IPH ( ρ = 0.413; P = .0259). The areas under the receiver operating characteristic curves for detecting histologic sections consisting primarily of IPH (relative area-histologic IPH &gt; 40.7%) tended to be greater for susceptibility (0.964) than for T1WI FSE-relative signal intensity (0.811). Marginal homogeneity was observed between susceptibility and histologic sections consisting primarily of IPH ( P = .0412), but not between T1-weighted FSE-relative signal intensity and histologic sections consisting primarily of IPH ( P = .1824).

CONCLUSIONS: Pre-carotid endarterectomy quantitative susceptibility mapping detects histologic IPH in cervical ICA stenosis more accurately than preoperative T1-weighted 3D-FSE imaging.

CEA
:   carotid endarterectomy
IPH
:   intraplaque hemorrhage
QSM
:   quantitative susceptibility mapping
RA
:   relative area
ROC
:   receiver operating characteristic
RSI
:   relative signal intensity" />
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    <title>Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy | American Journal of Neuroradiology</title>  
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      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Neurovascular/Stroke Imaging</span></span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Daisuke Oomori</span>, <span class="highwire-citation-author" data-delta="1">Yosuke Akamatsu</span>, <span class="highwire-citation-author" data-delta="2">Ikuko Uwano</span>, <span class="highwire-citation-author" data-delta="3">Futoshi Mori</span>, <span class="highwire-citation-author" data-delta="4">Tsuyoshi Matsuda</span>, <span class="highwire-citation-author" data-delta="5">Ryo Sugimoto</span>, <span class="highwire-citation-author" data-delta="6">Michiko Suzuki</span>, <span class="highwire-citation-author" data-delta="7">Shunrou Fujiwara</span>, <span class="highwire-citation-author" data-delta="8">Masakazu Kobayashi</span>, <span class="highwire-citation-author" data-delta="9">Makoto Sasaki</span>, <span class="highwire-citation-author" data-delta="10">Kunihiro Yoshioka</span>, <span class="highwire-citation-author" data-delta="11">Naoki Yanagawa</span> and <span class="highwire-citation-author" data-delta="12">Kuniaki Ogasawara</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">October 2024,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1461-1467; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A8356 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-110816--6111376781" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Daisuke Oomori </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Neurosurgery (D.O., Y.A., S.F., M.K., K.O.), Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Daisuke%2BOomori%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Oomori%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3ADaisuke%2BOomori%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Yosuke Akamatsu </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Neurosurgery (D.O., Y.A., S.F., M.K., K.O.), Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Yosuke%2BAkamatsu%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Akamatsu%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AYosuke%2BAkamatsu%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-8149-2988" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Yosuke Akamatsu</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">Ikuko Uwano </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Division of Ultrahigh Field MRI (I.U., F.M., T.M., M. Suzuki), Institute for Biomedical Sciences, Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Ikuko%2BUwano%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Uwano%20I&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AIkuko%2BUwano%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-3470-7795" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Ikuko Uwano</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Futoshi Mori </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Division of Ultrahigh Field MRI (I.U., F.M., T.M., M. Suzuki), Institute for Biomedical Sciences, Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Futoshi%2BMori%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mori%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AFutoshi%2BMori%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-3698-2507" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Futoshi Mori</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Tsuyoshi Matsuda </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Division of Ultrahigh Field MRI (I.U., F.M., T.M., M. Suzuki), Institute for Biomedical Sciences, Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Tsuyoshi%2BMatsuda%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Matsuda%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ATsuyoshi%2BMatsuda%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8914-8236" target="_blank" class="" data-icon-position="" 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class="author-site-search-link last"><a href="/search/author1%3ARyo%2BSugimoto%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">Michiko Suzuki </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Radiology (M.S, K.Y), Iwate Medical University School of Medicine, Yahaba-cho, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Michiko%2BSuzuki%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Suzuki%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" 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class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Fujiwara%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AShunrou%2BFujiwara%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-5800-515X" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Shunrou Fujiwara</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">Masakazu Kobayashi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Neurosurgery (D.O., Y.A., S.F., M.K., K.O.), Iwate Medical University School of Medicine, Yahaba-cho, 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 45</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 10 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Oct 2024 </div></div>
      
      
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      <div class="highwire-cite-title">Diagnostic Accuracy of Preoperative Quantitative Susceptibility Mapping for Detecting Histologic Intraplaque Hemorrhage in Cervical ICA Stenosis in Patients Undergoing Carotid Endarterectomy</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Daisuke</span> <span class="nlm-surname">Oomori</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Yosuke</span> <span class="nlm-surname">Akamatsu</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Ikuko</span> <span class="nlm-surname">Uwano</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Futoshi</span> <span class="nlm-surname">Mori</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Tsuyoshi</span> <span class="nlm-surname">Matsuda</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Ryo</span> <span class="nlm-surname">Sugimoto</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Michiko</span> <span class="nlm-surname">Suzuki</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Shunrou</span> <span class="nlm-surname">Fujiwara</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Masakazu</span> <span class="nlm-surname">Kobayashi</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Makoto</span> <span class="nlm-surname">Sasaki</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">Kunihiro</span> <span class="nlm-surname">Yoshioka</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">Naoki</span> <span class="nlm-surname">Yanagawa</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">Kuniaki</span> <span class="nlm-surname">Ogasawara</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1461-1467; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8356 </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Daisuke</span> <span class="nlm-surname">Oomori</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Yosuke</span> <span class="nlm-surname">Akamatsu</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Ikuko</span> <span class="nlm-surname">Uwano</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Futoshi</span> <span class="nlm-surname">Mori</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Tsuyoshi</span> <span class="nlm-surname">Matsuda</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Ryo</span> <span class="nlm-surname">Sugimoto</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Michiko</span> <span class="nlm-surname">Suzuki</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Shunrou</span> <span class="nlm-surname">Fujiwara</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Masakazu</span> <span class="nlm-surname">Kobayashi</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Makoto</span> <span class="nlm-surname">Sasaki</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">Kunihiro</span> <span class="nlm-surname">Yoshioka</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">Naoki</span> <span class="nlm-surname">Yanagawa</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">Kuniaki</span> <span class="nlm-surname">Ogasawara</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1461-1467; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8356 </span></div>
  
  
  
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