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<!DOCTYPE html>
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<meta name="citation_funding_source" content="citation_grant_number=Ajut Carles Margarit 2023, recipient Marc Rodrigo-Gisbert;" />
<meta name="issue_cover_image" content="http://ajnr-stage2.stage.highwire.org/sites/default/files/highwire/ajnr/45/11.cover-source.jpg" />
<meta name="type" content="article" />
<meta name="category" content="research-article" />
<meta name="HW.identifier" content="/ajnr/45/11/1701.atom" />
<meta name="HW.pisa" content="ajnr;45/11/1701" />
<meta name="DC.Format" content="text/html" />
<meta name="DC.Language" content="en" />
<meta name="DC.Title" content="Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting" />
<meta name="DC.Identifier" content="10.3174/ajnr.A8374" />
<meta name="DC.Date" content="2024-11-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2024 by American Journal of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.

MATERIALS AND METHODS: Patients from 2 comprehensive stroke centers were reviewed (2020−2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0−2 and mortality.

RESULTS: After a median of 3 (interquartile range, 2−4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (&gt;50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; P  = .932), significant stenosis (33.3% versus 55.0%; P  = .203), early symptomatic re-occlusion (0% versus 8.0%; P  = .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; P  = .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; P  = .112). At 90 days, mRS 0−2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; P  = .086) and mortality (26.3% versus 12.0%; P  = .223) were also similar.

CONCLUSIONS: In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.

A&amp;S
:   angioplasty and stenting
eTICI
:   expanded TICI
EVT
:   endovascular treatment
IA
:   intra-arterial
ICAD
:   intracranial atherosclerotic disease
ICAS-LVO
:   intracranial atherosclerosis–related large-vessel occlusion
IQR
:   interquartile range
LVO
:   large-vessel occlusion
MT
:   mechanical thrombectomy
SAIL
:   Stent retriever–AssIsted Lysis
sICH
:   symptomatic intracerebral hemorrhage
SR
:   stent retriever" />
<meta name="DC.Contributor" content="Marc Rodrigo-Gisbert" />
<meta name="DC.Contributor" content="Matúš Hoferica" />
<meta name="DC.Contributor" content="Alvaro García-Tornel" />
<meta name="DC.Contributor" content="Manuel Requena" />
<meta name="DC.Contributor" content="Marta Rubiera" />
<meta name="DC.Contributor" content="Marta De Dios Lascuevas" />
<meta name="DC.Contributor" content="Marta Olivé-Gadea" />
<meta name="DC.Contributor" content="Francesco Diana" />
<meta name="DC.Contributor" content="Federica Rizzo" />
<meta name="DC.Contributor" content="Marian Muchada" />
<meta name="DC.Contributor" content="Tomás Carmona" />
<meta name="DC.Contributor" content="Noelia Rodriguez-Villatoro" />
<meta name="DC.Contributor" content="David Rodríguez-Luna" />
<meta name="DC.Contributor" content="Jesus Juega" />
<meta name="DC.Contributor" content="Jorge Pagola" />
<meta name="DC.Contributor" content="David Hernández" />
<meta name="DC.Contributor" content="Carlos A. Molina" />
<meta name="DC.Contributor" content="Alejandro Tomasello" />
<meta name="DC.Contributor" content="Christophe Cognard" />
<meta name="DC.Contributor" content="Marc Ribó" />
<meta name="article:published_time" content="2024-11-01" />
<meta name="article:section" content="Neurointervention" />
<meta name="citation_title" content="Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Patients from 2 comprehensive stroke centers were reviewed (2020−2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0−2 and mortality.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;After a median of 3 (interquartile range, 2−4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (&amp;gt;50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; &lt;i&gt;P &lt;/i&gt;= .932), significant stenosis (33.3% versus 55.0%; &lt;i&gt;P &lt;/i&gt;= .203), early symptomatic re-occlusion (0% versus 8.0%; &lt;i&gt;P &lt;/i&gt;= .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; &lt;i&gt;P &lt;/i&gt;= .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; &lt;i&gt;P &lt;/i&gt;= .112). At 90 days, mRS 0−2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; &lt;i&gt;P &lt;/i&gt;= .086) and mortality (26.3% versus 12.0%; &lt;i&gt;P &lt;/i&gt;= .223) were also similar.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="2024/11/01" />
<meta name="citation_mjid" content="ajnr;45/11/1701" />
<meta name="citation_id" content="45/11/1701" />
<meta name="citation_public_url" content="http://ajnr-stage2.stage.highwire.org/content/45/11/1701" />
<meta name="citation_abstract_html_url" content="http://ajnr-stage2.stage.highwire.org/content/45/11/1701.abstract" />
<meta name="citation_full_html_url" content="http://ajnr-stage2.stage.highwire.org/content/45/11/1701.full" />
<meta name="citation_pdf_url" content="http://ajnr-stage2.stage.highwire.org/content/ajnr/45/11/1701.full.pdf" />
<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
<meta name="citation_doi" content="10.3174/ajnr.A8374" />
<meta name="citation_pmid" content="38849135" />
<meta name="citation_volume" content="45" />
<meta name="citation_issue" content="11" />
<meta name="citation_article_type" content="Research Article" />
<meta name="citation_section" content="Neurointervention" />
<meta name="citation_firstpage" content="1701" />
<meta name="citation_lastpage" content="1707" />
<meta name="citation_author" content="Marc Rodrigo-Gisbert" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-7953-3795" />
<meta name="citation_author" content="Matúš Hoferica" />
<meta name="citation_author_institution" content="cDepartment of Diagnostic Neuroradiology (M.H., C.C.), Hôpital Purpan, Centre Hospitalier Universitaire, Toulouse, France" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-5830-0722" />
<meta name="citation_author" content="Alvaro García-Tornel" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0003-3633-3002" />
<meta name="citation_author" content="Manuel Requena" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-5671-6484" />
<meta name="citation_author" content="Marta Rubiera" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-8100-9477" />
<meta name="citation_author" content="Marta De Dios Lascuevas" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author" content="Marta Olivé-Gadea" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0003-4637-1598" />
<meta name="citation_author" content="Francesco Diana" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-3245-917X" />
<meta name="citation_author" content="Federica Rizzo" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author" content="Marian Muchada" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author" content="Tomás Carmona" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author" content="Noelia Rodriguez-Villatoro" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-8833-4720" />
<meta name="citation_author" content="David Rodríguez-Luna" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-8053-4536" />
<meta name="citation_author" content="Jesus Juega" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0003-1309-0730" />
<meta name="citation_author" content="Jorge Pagola" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-0725-1369" />
<meta name="citation_author" content="David Hernández" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-6715-4547" />
<meta name="citation_author" content="Carlos A. Molina" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author" content="Alejandro Tomasello" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_institution" content="dDepartment of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-6736-1535" />
<meta name="citation_author" content="Christophe Cognard" />
<meta name="citation_author_institution" content="cDepartment of Diagnostic Neuroradiology (M.H., C.C.), Hôpital Purpan, Centre Hospitalier Universitaire, Toulouse, France" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0003-4287-2627" />
<meta name="citation_author" content="Marc Ribó" />
<meta name="citation_author_institution" content="aFrom the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain" />
<meta name="citation_author_institution" content="bDepartment de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-9242-043X" />
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<meta name="twitter:title" content="Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.

MATERIALS AND METHODS: Patients from 2 comprehensive stroke centers were reviewed (2020−2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0−2 and mortality.

RESULTS: After a median of 3 (interquartile range, 2−4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (&gt;50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; P  = .932), significant stenosis (33.3% versus 55.0%; P  = .203), early symptomatic re-occlusion (0% versus 8.0%; P  = .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; P  = .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; P  = .112). At 90 days, mRS 0−2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; P  = .086) and mortality (26.3% versus 12.0%; P  = .223) were also similar.

CONCLUSIONS: In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.

A&amp;S
:   angioplasty and stenting
eTICI
:   expanded TICI
EVT
:   endovascular treatment
IA
:   intra-arterial
ICAD
:   intracranial atherosclerotic disease
ICAS-LVO
:   intracranial atherosclerosis–related large-vessel occlusion
IQR
:   interquartile range
LVO
:   large-vessel occlusion
MT
:   mechanical thrombectomy
SAIL
:   Stent retriever–AssIsted Lysis
sICH
:   symptomatic intracerebral hemorrhage
SR
:   stent retriever" />
<meta name="og-title" property="og:title" content="Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/45/11/1701" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.

MATERIALS AND METHODS: Patients from 2 comprehensive stroke centers were reviewed (2020−2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0−2 and mortality.

RESULTS: After a median of 3 (interquartile range, 2−4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (&gt;50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; P  = .932), significant stenosis (33.3% versus 55.0%; P  = .203), early symptomatic re-occlusion (0% versus 8.0%; P  = .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; P  = .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; P  = .112). At 90 days, mRS 0−2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; P  = .086) and mortality (26.3% versus 12.0%; P  = .223) were also similar.

CONCLUSIONS: In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.

A&amp;S
:   angioplasty and stenting
eTICI
:   expanded TICI
EVT
:   endovascular treatment
IA
:   intra-arterial
ICAD
:   intracranial atherosclerotic disease
ICAS-LVO
:   intracranial atherosclerosis–related large-vessel occlusion
IQR
:   interquartile range
LVO
:   large-vessel occlusion
MT
:   mechanical thrombectomy
SAIL
:   Stent retriever–AssIsted Lysis
sICH
:   symptomatic intracerebral hemorrhage
SR
:   stent retriever" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node111452--5" data-node-nid="111452" id="top-node-111452--61361909756" data-pisa="ajnr;45/11/1701" data-pisa-master="ajnr;ajnr.A8374" data-apath="/ajnr/45/11/1701.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Neurointervention</span></span></div>
  
      <div class="highwire-cite-access"><span class="highwire-citation-access highwire-citation-access-check" data-pisa-id="ajnr;ajnr.A8374" data-atom-uri="/ajnr/45/11/1701.atom" data-request-view="full"></span></div>
  
      <h1 class="highwire-cite-title" id="page-title">Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Marc Rodrigo-Gisbert</span>, <span class="highwire-citation-author" data-delta="1">Matúš Hoferica</span>, <span class="highwire-citation-author" data-delta="2">Alvaro García-Tornel</span>, <span class="highwire-citation-author" data-delta="3">Manuel Requena</span>, <span class="highwire-citation-author" data-delta="4">Marta Rubiera</span>, <span class="highwire-citation-author" data-delta="5">Marta De Dios Lascuevas</span>, <span class="highwire-citation-author" data-delta="6">Marta Olivé-Gadea</span>, <span class="highwire-citation-author" data-delta="7">Francesco Diana</span>, <span class="highwire-citation-author" data-delta="8">Federica Rizzo</span>, <span class="highwire-citation-author" data-delta="9">Marian Muchada</span>, <span class="highwire-citation-author" data-delta="10">Tomás Carmona</span>, <span class="highwire-citation-author" data-delta="11">Noelia Rodriguez-Villatoro</span>, <span class="highwire-citation-author" data-delta="12">David Rodríguez-Luna</span>, <span class="highwire-citation-author" data-delta="13">Jesus Juega</span>, <span class="highwire-citation-author" data-delta="14">Jorge Pagola</span>, <span class="highwire-citation-author" data-delta="15">David Hernández</span>, <span class="highwire-citation-author" data-delta="16">Carlos A. Molina</span>, <span class="highwire-citation-author" data-delta="17">Alejandro Tomasello</span>, <span class="highwire-citation-author" data-delta="18">Christophe Cognard</span> and <span class="highwire-citation-author" data-delta="19">Marc Ribó</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">November 2024,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(11) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1701-1707; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A8374 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-111452--61361909756" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Marc Rodrigo-Gisbert </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marc%2BRodrigo-Gisbert%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rodrigo-Gisbert%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMarc%2BRodrigo-Gisbert%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7953-3795" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Marc Rodrigo-Gisbert</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Matúš Hoferica </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Diagnostic Neuroradiology (M.H., C.C.), Hôpital Purpan, Centre Hospitalier Universitaire, Toulouse, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Mat%C3%BA%C5%A1%2BHoferica%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Hoferica%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMat%25C3%25BA%25C5%25A1%2BHoferica%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-5830-0722" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Matúš Hoferica</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">Alvaro García-Tornel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Alvaro%2BGarc%C3%ADa-Tornel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Garc%C3%ADa-Tornel%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AAlvaro%2BGarc%25C3%25ADa-Tornel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-3633-3002" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Alvaro García-Tornel</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Manuel Requena </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Manuel%2BRequena%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Requena%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AManuel%2BRequena%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-5671-6484" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Manuel Requena</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Marta Rubiera </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marta%2BRubiera%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rubiera%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMarta%2BRubiera%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8100-9477" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Marta Rubiera</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">Marta De Dios Lascuevas </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marta%2BDe%2BDios%2BLascuevas%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lascuevas%20MD&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMarta%2BDe%2BDios%2BLascuevas%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">Marta Olivé-Gadea </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marta%2BOliv%C3%A9-Gadea%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Oliv%C3%A9-Gadea%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMarta%2BOliv%25C3%25A9-Gadea%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-4637-1598" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Marta Olivé-Gadea</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">Francesco Diana </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Francesco%2BDiana%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Diana%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AFrancesco%2BDiana%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-3245-917X" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Francesco Diana</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">Federica Rizzo </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Federica%2BRizzo%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rizzo%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AFederica%2BRizzo%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">Marian Muchada </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marian%2BMuchada%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Muchada%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMarian%2BMuchada%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-10"><div class="author-tooltip-name">Tomás Carmona </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Tom%C3%A1s%2BCarmona%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Carmona%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3ATom%25C3%25A1s%2BCarmona%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-11"><div class="author-tooltip-name">Noelia Rodriguez-Villatoro </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Noelia%2BRodriguez-Villatoro%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rodriguez-Villatoro%20N&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ANoelia%2BRodriguez-Villatoro%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-8833-4720" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Noelia Rodriguez-Villatoro</a></li></ul></div><div class="author-tooltip-12"><div class="author-tooltip-name">David Rodríguez-Luna </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=David%2BRodr%C3%ADguez-Luna%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rodr%C3%ADguez-Luna%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ADavid%2BRodr%25C3%25ADguez-Luna%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8053-4536" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for David Rodríguez-Luna</a></li></ul></div><div class="author-tooltip-13"><div class="author-tooltip-name">Jesus Juega </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Jesus%2BJuega%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Juega%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJesus%2BJuega%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-1309-0730" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Jesus Juega</a></li></ul></div><div class="author-tooltip-14"><div class="author-tooltip-name">Jorge Pagola </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Jorge%2BPagola%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Pagola%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJorge%2BPagola%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0725-1369" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Jorge Pagola</a></li></ul></div><div class="author-tooltip-15"><div class="author-tooltip-name">David Hernández </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=David%2BHern%C3%A1ndez%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Hern%C3%A1ndez%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ADavid%2BHern%25C3%25A1ndez%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6715-4547" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for David Hernández</a></li></ul></div><div class="author-tooltip-16"><div class="author-tooltip-name">Carlos A. Molina </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Carlos%2BA.%2BMolina%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Molina%20CA&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3ACarlos%2BA.%2BMolina%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-17"><div class="author-tooltip-name">Alejandro Tomasello </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neuroradiology (M. Requena, M.D.D.L., F.D., T.C., D.H., A.T.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Alejandro%2BTomasello%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Tomasello%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AAlejandro%2BTomasello%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6736-1535" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Alejandro Tomasello</a></li></ul></div><div class="author-tooltip-18"><div class="author-tooltip-name">Christophe Cognard </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Diagnostic Neuroradiology (M.H., C.C.), Hôpital Purpan, Centre Hospitalier Universitaire, Toulouse, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Christophe%2BCognard%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Cognard%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AChristophe%2BCognard%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-4287-2627" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Christophe Cognard</a></li></ul></div><div class="author-tooltip-19"><div class="author-tooltip-name">Marc Ribó </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Stroke Unit, Department of Neurology (M.R.-G., A.G.-T., M. Requena, M. Rubiera, M.O.-G., F.R., M.M., N.R.-V., D.R.-L., J.J., J.P., C.A.M., M.R.), Hospital Universitari Vall d’Hebron, Barcelona, Spain</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department de Medicina (M.R.-G, A.G.-T., M. Requena, M. Rubiera, M.D.D.L., M.O.-G., F.D., F.R., M.M., T.C., N.R.-V., D.R.-L., J.J., J.P., D.H., C.A.M., A.T., M.R.), Universitat Autònoma de Barcelona, Barcelona, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marc%2BRib%C3%B3%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rib%C3%B3%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMarc%2BRib%25C3%25B3%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-9242-043X" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Marc Ribó</a></li></ul></div></div></div>  </div>

  
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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" data-highwire-cite-ref-tooltip-instance="highwire_reflinks_tooltip" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="article abstract-view "><span class="highwire-journal-article-marker-start"></span><div class="section abstract" id="abstract-1"><h2>Abstract</h2><div id="sec-1" class="subsection"><p id="p-1"><strong>BACKGROUND AND PURPOSE:</strong> Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.</p></div><div id="sec-2" class="subsection"><p id="p-2"><strong>MATERIALS AND METHODS:</strong> Patients from 2 comprehensive stroke centers were reviewed (2020−2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0−2 and mortality.</p></div><div id="sec-3" class="subsection"><p id="p-3"><strong>RESULTS:</strong> After a median of 3 (interquartile range, 2−4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (&gt;50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; <em>P </em>= .932), significant stenosis (33.3% versus 55.0%; <em>P </em>= .203), early symptomatic re-occlusion (0% versus 8.0%; <em>P </em>= .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; <em>P </em>= .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; <em>P </em>= .112). At 90 days, mRS 0−2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; <em>P </em>= .086) and mortality (26.3% versus 12.0%; <em>P </em>= .223) were also similar.</p></div><div id="sec-4" class="subsection"><p id="p-4"><strong>CONCLUSIONS:</strong> In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.</p></div></div><div class="section glossary" id="glossary-1"><h2 class="">ABBREVIATIONS:</h2><dl id="def-list-1"><dt id="def-item-1">A&amp;S<span class="def-item-dt-sep"></span></dt><dd>angioplasty and stenting<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">eTICI<span class="def-item-dt-sep"></span></dt><dd>expanded TICI<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">EVT<span class="def-item-dt-sep"></span></dt><dd>endovascular treatment<span class="def-item-dd-sep"></span></dd><dt id="def-item-4">IA<span class="def-item-dt-sep"></span></dt><dd>intra-arterial<span class="def-item-dd-sep"></span></dd><dt id="def-item-5">ICAD<span class="def-item-dt-sep"></span></dt><dd>intracranial atherosclerotic disease<span class="def-item-dd-sep"></span></dd><dt id="def-item-6">ICAS-LVO<span class="def-item-dt-sep"></span></dt><dd>intracranial atherosclerosis–related large-vessel occlusion<span class="def-item-dd-sep"></span></dd><dt id="def-item-7">IQR<span class="def-item-dt-sep"></span></dt><dd>interquartile range<span class="def-item-dd-sep"></span></dd><dt id="def-item-8">LVO<span class="def-item-dt-sep"></span></dt><dd>large-vessel occlusion<span class="def-item-dd-sep"></span></dd><dt id="def-item-9">MT<span class="def-item-dt-sep"></span></dt><dd>mechanical thrombectomy<span class="def-item-dd-sep"></span></dd><dt id="def-item-10">SAIL<span class="def-item-dt-sep"></span></dt><dd>Stent retriever–AssIsted Lysis<span class="def-item-dd-sep"></span></dd><dt id="def-item-11">sICH<span class="def-item-dt-sep"></span></dt><dd>symptomatic intracerebral hemorrhage<span class="def-item-dd-sep"></span></dd><dt id="def-item-12">SR<span class="def-item-dt-sep"></span></dt><dd>stent retriever</dd></dl></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2024 by American Journal of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div><a href="http://ajnr-stage2.stage.highwire.org/content/45/11/1701.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Marc</span> <span class="nlm-surname">Rodrigo-Gisbert</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Matúš</span> <span class="nlm-surname">Hoferica</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Alvaro</span> <span class="nlm-surname">García-Tornel</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Manuel</span> <span class="nlm-surname">Requena</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Marta</span> <span class="nlm-surname">Rubiera</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Marta De Dios</span> <span class="nlm-surname">Lascuevas</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Marta</span> <span class="nlm-surname">Olivé-Gadea</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Francesco</span> <span class="nlm-surname">Diana</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Federica</span> <span class="nlm-surname">Rizzo</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Marian</span> <span class="nlm-surname">Muchada</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">Tomás</span> <span class="nlm-surname">Carmona</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">Noelia</span> <span class="nlm-surname">Rodriguez-Villatoro</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">David</span> <span class="nlm-surname">Rodríguez-Luna</span></span>, <span class="highwire-citation-author" data-delta="13"><span class="nlm-given-names">Jesus</span> <span class="nlm-surname">Juega</span></span>, <span class="highwire-citation-author" data-delta="14"><span class="nlm-given-names">Jorge</span> <span class="nlm-surname">Pagola</span></span>, <span class="highwire-citation-author" data-delta="15"><span class="nlm-given-names">David</span> <span class="nlm-surname">Hernández</span></span>, <span class="highwire-citation-author" data-delta="16"><span class="nlm-given-names">Carlos A.</span> <span class="nlm-surname">Molina</span></span>, <span class="highwire-citation-author" data-delta="17"><span class="nlm-given-names">Alejandro</span> <span class="nlm-surname">Tomasello</span></span>, <span class="highwire-citation-author" data-delta="18"><span class="nlm-given-names">Christophe</span> <span class="nlm-surname">Cognard</span></span>, <span class="highwire-citation-author" data-delta="19"><span class="nlm-given-names">Marc</span> <span class="nlm-surname">Ribó</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Nov 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(11) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1701-1707; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8374 </span></div>
  
  
  
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      <div class="highwire-cite-title">Stent-Assisted Lysis: A Bailout Technique</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Marc</span> <span class="nlm-surname">Rodrigo-Gisbert</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Matúš</span> <span class="nlm-surname">Hoferica</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Alvaro</span> <span class="nlm-surname">García-Tornel</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Manuel</span> <span class="nlm-surname">Requena</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Marta</span> <span class="nlm-surname">Rubiera</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Marta De Dios</span> <span class="nlm-surname">Lascuevas</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Marta</span> <span class="nlm-surname">Olivé-Gadea</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Francesco</span> <span class="nlm-surname">Diana</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Federica</span> <span class="nlm-surname">Rizzo</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Marian</span> <span class="nlm-surname">Muchada</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">Tomás</span> <span class="nlm-surname">Carmona</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">Noelia</span> <span class="nlm-surname">Rodriguez-Villatoro</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">David</span> <span class="nlm-surname">Rodríguez-Luna</span></span>, <span class="highwire-citation-author" data-delta="13"><span class="nlm-given-names">Jesus</span> <span class="nlm-surname">Juega</span></span>, <span class="highwire-citation-author" data-delta="14"><span class="nlm-given-names">Jorge</span> <span class="nlm-surname">Pagola</span></span>, <span class="highwire-citation-author" data-delta="15"><span class="nlm-given-names">David</span> <span class="nlm-surname">Hernández</span></span>, <span class="highwire-citation-author" data-delta="16"><span class="nlm-given-names">Carlos A.</span> <span class="nlm-surname">Molina</span></span>, <span class="highwire-citation-author" data-delta="17"><span class="nlm-given-names">Alejandro</span> <span class="nlm-surname">Tomasello</span></span>, <span class="highwire-citation-author" data-delta="18"><span class="nlm-given-names">Christophe</span> <span class="nlm-surname">Cognard</span></span>, <span class="highwire-citation-author" data-delta="19"><span class="nlm-given-names">Marc</span> <span class="nlm-surname">Ribó</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Nov 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(11) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1701-1707; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8374 </span></div>
  
  
  
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