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<meta name="DC.Title" content="The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis" />
<meta name="DC.Identifier" content="10.3174/ajnr.A5182" />
<meta name="DC.Date" content="2017-05-04" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND: Sonography-guided fine-needle aspiration leads to relatively frequent cases of indeterminate cytology for the diagnosis of thyroid nodules.

PURPOSE: Our aim was to evaluate the efficacy and safety of core needle biopsy for the examination of thyroid nodules with initially indeterminate results on fine-needle aspiration.

DATA SOURCES: A computerized search of the MEDLINE and Embase databases was performed to identify relevant original articles.

STUDY SELECTION: Studies investigating the use of core needle biopsy for thyroid nodules with initially indeterminate results on previous fine-needle aspiration were eligible for inclusion.

DATA ANALYSIS: The pooled proportions for nondiagnostic results, inconclusive results, malignancy on core needle biopsy, the ability of core needle biopsy to diagnose malignancy, and the related complications of the procedure were analyzed.

DATA SYNTHESIS: The meta-analytic pooling was based on a random-effects model. Nine eligible studies, involving 2240 patients with 2245 thyroid nodules, were included. The pooled proportion for nondiagnostic results was 1.8% (95% CI, 0.4%–3.2%), and the pooled proportion for inconclusive results was 25.1% (95% CI, 15.4%–34.9%). The pooled proportion for malignancy was 18.9% (95% CI, 8.4%–29.5%). With regard to the diagnostic performance for malignancy, the sensitivity of core needle biopsy varied, ranging from 44.7% to 85.0%, but the specificity was 100% in all cases. No major complications of core needle biopsy were observed.

LIMITATIONS: The relatively small number of included studies and retrospective nature were limitations.

CONCLUSIONS: Core needle biopsy has low nondiagnostic result rates and high specificity for the diagnosis of malignancy. It is a safe diagnostic technique with a higher diagnostic yield, especially when molecular testing is not available or fine-needle aspiration did not yield enough cells for molecular testing.

### Abbreviations

AUS
:   atypia of undetermined significance
CNB
:   core needle biopsy
FLUS
:   follicular lesion of undetermined significance
FNA
:   fine-needle aspiration
US
:   ultrasound" />
<meta name="DC.Contributor" content="C.H. Suh" />
<meta name="DC.Contributor" content="J.H. Baek" />
<meta name="DC.Contributor" content="C. Park" />
<meta name="DC.Contributor" content="Y.J. Choi" />
<meta name="DC.Contributor" content="J.H. Lee" />
<meta name="article:published_time" content="2017-05-04" />
<meta name="article:section" content="HEAD &amp;amp; NECK" />
<meta name="citation_title" content="The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND:&lt;/h3&gt;
&lt;p&gt;Sonography-guided fine-needle aspiration leads to relatively frequent cases of indeterminate cytology for the diagnosis of thyroid nodules.&lt;/p&gt;&lt;h3&gt;PURPOSE:&lt;/h3&gt;
&lt;p&gt;Our aim was to evaluate the efficacy and safety of core needle biopsy for the examination of thyroid nodules with initially indeterminate results on fine-needle aspiration.&lt;/p&gt;&lt;h3&gt;DATA SOURCES:&lt;/h3&gt;
&lt;p&gt;A computerized search of the MEDLINE and Embase databases was performed to identify relevant original articles.&lt;/p&gt;&lt;h3&gt;STUDY SELECTION:&lt;/h3&gt;
&lt;p&gt;Studies investigating the use of core needle biopsy for thyroid nodules with initially indeterminate results on previous fine-needle aspiration were eligible for inclusion.&lt;/p&gt;&lt;h3&gt;DATA ANALYSIS:&lt;/h3&gt;
&lt;p&gt;The pooled proportions for nondiagnostic results, inconclusive results, malignancy on core needle biopsy, the ability of core needle biopsy to diagnose malignancy, and the related complications of the procedure were analyzed.&lt;/p&gt;&lt;h3&gt;DATA SYNTHESIS:&lt;/h3&gt;
&lt;p&gt;The meta-analytic pooling was based on a random-effects model. Nine eligible studies, involving 2240 patients with 2245 thyroid nodules, were included. The pooled proportion for nondiagnostic results was 1.8% (95% CI, 0.4%–3.2%), and the pooled proportion for inconclusive results was 25.1% (95% CI, 15.4%–34.9%). The pooled proportion for malignancy was 18.9% (95% CI, 8.4%–29.5%). With regard to the diagnostic performance for malignancy, the sensitivity of core needle biopsy varied, ranging from 44.7% to 85.0%, but the specificity was 100% in all cases. No major complications of core needle biopsy were observed.&lt;/p&gt;&lt;h3&gt;LIMITATIONS:&lt;/h3&gt;
&lt;p&gt;The relatively small number of included studies and retrospective nature were limitations.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Core needle biopsy has low nondiagnostic result rates and high specificity for the diagnosis of malignancy. It is a safe diagnostic technique with a higher diagnostic yield, especially when molecular testing is not available or fine-needle aspiration did not yield enough cells for molecular testing.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="C.H. Suh" />
<meta name="citation_author_institution" content="From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea." />
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<meta name="citation_author" content="J.H. Baek" />
<meta name="citation_author_institution" content="From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea." />
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<meta name="citation_author" content="C. Park" />
<meta name="citation_author_institution" content="From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea." />
<meta name="citation_author_orcid" content="http://orcid.org/0000-0002-9838-8757" />
<meta name="citation_author" content="Y.J. Choi" />
<meta name="citation_author_institution" content="From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea." />
<meta name="citation_author_orcid" content="http://orcid.org/0000-0001-7098-5042" />
<meta name="citation_author" content="J.H. Lee" />
<meta name="citation_author_institution" content="From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea." />
<meta name="citation_author_orcid" content="http://orcid.org/0000-0002-0021-4477" />
<meta name="twitter:title" content="The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis" />
<meta name="twitter:card" content="summary" />
<meta name="twitter:description" content="BACKGROUND: Sonography-guided fine-needle aspiration leads to relatively frequent cases of indeterminate cytology for the diagnosis of thyroid nodules.

PURPOSE: Our aim was to evaluate the efficacy and safety of core needle biopsy for the examination of thyroid nodules with initially indeterminate results on fine-needle aspiration.

DATA SOURCES: A computerized search of the MEDLINE and Embase databases was performed to identify relevant original articles.

STUDY SELECTION: Studies investigating the use of core needle biopsy for thyroid nodules with initially indeterminate results on previous fine-needle aspiration were eligible for inclusion.

DATA ANALYSIS: The pooled proportions for nondiagnostic results, inconclusive results, malignancy on core needle biopsy, the ability of core needle biopsy to diagnose malignancy, and the related complications of the procedure were analyzed.

DATA SYNTHESIS: The meta-analytic pooling was based on a random-effects model. Nine eligible studies, involving 2240 patients with 2245 thyroid nodules, were included. The pooled proportion for nondiagnostic results was 1.8% (95% CI, 0.4%–3.2%), and the pooled proportion for inconclusive results was 25.1% (95% CI, 15.4%–34.9%). The pooled proportion for malignancy was 18.9% (95% CI, 8.4%–29.5%). With regard to the diagnostic performance for malignancy, the sensitivity of core needle biopsy varied, ranging from 44.7% to 85.0%, but the specificity was 100% in all cases. No major complications of core needle biopsy were observed.

LIMITATIONS: The relatively small number of included studies and retrospective nature were limitations.

CONCLUSIONS: Core needle biopsy has low nondiagnostic result rates and high specificity for the diagnosis of malignancy. It is a safe diagnostic technique with a higher diagnostic yield, especially when molecular testing is not available or fine-needle aspiration did not yield enough cells for molecular testing.

### Abbreviations

AUS
:   atypia of undetermined significance
CNB
:   core needle biopsy
FLUS
:   follicular lesion of undetermined significance
FNA
:   fine-needle aspiration
US
:   ultrasound" />
<meta name="og-title" property="og:title" content="The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/early/2017/05/04/ajnr.A5182" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND: Sonography-guided fine-needle aspiration leads to relatively frequent cases of indeterminate cytology for the diagnosis of thyroid nodules.

PURPOSE: Our aim was to evaluate the efficacy and safety of core needle biopsy for the examination of thyroid nodules with initially indeterminate results on fine-needle aspiration.

DATA SOURCES: A computerized search of the MEDLINE and Embase databases was performed to identify relevant original articles.

STUDY SELECTION: Studies investigating the use of core needle biopsy for thyroid nodules with initially indeterminate results on previous fine-needle aspiration were eligible for inclusion.

DATA ANALYSIS: The pooled proportions for nondiagnostic results, inconclusive results, malignancy on core needle biopsy, the ability of core needle biopsy to diagnose malignancy, and the related complications of the procedure were analyzed.

DATA SYNTHESIS: The meta-analytic pooling was based on a random-effects model. Nine eligible studies, involving 2240 patients with 2245 thyroid nodules, were included. The pooled proportion for nondiagnostic results was 1.8% (95% CI, 0.4%–3.2%), and the pooled proportion for inconclusive results was 25.1% (95% CI, 15.4%–34.9%). The pooled proportion for malignancy was 18.9% (95% CI, 8.4%–29.5%). With regard to the diagnostic performance for malignancy, the sensitivity of core needle biopsy varied, ranging from 44.7% to 85.0%, but the specificity was 100% in all cases. No major complications of core needle biopsy were observed.

LIMITATIONS: The relatively small number of included studies and retrospective nature were limitations.

CONCLUSIONS: Core needle biopsy has low nondiagnostic result rates and high specificity for the diagnosis of malignancy. It is a safe diagnostic technique with a higher diagnostic yield, especially when molecular testing is not available or fine-needle aspiration did not yield enough cells for molecular testing.

### Abbreviations

AUS
:   atypia of undetermined significance
CNB
:   core needle biopsy
FLUS
:   follicular lesion of undetermined significance
FNA
:   fine-needle aspiration
US
:   ultrasound" />
<meta name="og-type" property="og:type" content="article" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node54352--5" data-node-nid="54352" id="top-node-54352--6842357723" data-pisa="ajnr;ajnr.A5182v1" data-pisa-master="ajnr;ajnr.A5182" data-apath="/ajnr/early/2017/05/04/ajnr.A5182.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
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      <h1 class="highwire-cite-title" id="page-title">The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">C.H. Suh</span>, <span class="highwire-citation-author" data-delta="1">J.H. Baek</span>, <span class="highwire-citation-author" data-delta="2">C. Park</span>, <span class="highwire-citation-author" data-delta="3">Y.J. Choi</span> and <span class="highwire-citation-author" data-delta="4">J.H. Lee</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 2017,  </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A5182 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-54352--6842357723" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">C.H. Suh </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.H.%2BSuh%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Suh%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.H.%2BSuh%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-4737-0530" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C.H. Suh</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">J.H. Baek </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.H.%2BBaek%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Baek%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.H.%2BBaek%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-0480-4754" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.H. Baek</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">C. Park </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BPark%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Park%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BPark%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-9838-8757" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Park</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Y.J. Choi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.J.%2BChoi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Choi%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AY.J.%2BChoi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0001-7098-5042" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Y.J. Choi</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">J.H. Lee </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Radiology and Research Institute of Radiology (C.H.S., J.H.B.,Y.J.C., J.H.L.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; Department of Radiology (C.H.S., C.P.), Namwon Medical Center, Jeollabuk-Do, Republic of Korea; and Department of Radiology (C.P.), Chonnam National University Hospital, Gwangju, Republic of Korea.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.H.%2BLee%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lee%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.H.%2BLee%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-0021-4477" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.H. 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      <div class="highwire-cite-title">The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">C.H.</span> <span class="nlm-surname">Suh</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">J.H.</span> <span class="nlm-surname">Baek</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Park</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Y.J.</span> <span class="nlm-surname">Choi</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.H.</span> <span class="nlm-surname">Lee</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 2017, </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A5182 </span></div>
  
  
  
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      <div class="highwire-cite-title">The Role of Core Needle Biopsy for Thyroid Nodules with Initially Indeterminate Results on Previous Fine-Needle Aspiration: A Systematic Review and Meta-Analysis</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">C.H.</span> <span class="nlm-surname">Suh</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">J.H.</span> <span class="nlm-surname">Baek</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Park</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Y.J.</span> <span class="nlm-surname">Choi</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.H.</span> <span class="nlm-surname">Lee</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 2017, </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A5182 </span></div>
  
  
  
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