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<meta name="DC.Title" content="Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging." />
<meta name="DC.Date" content="1992-07-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="Copyright © American Society of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="PURPOSE To investigate the role of dynamic MR imaging in the differentiation of neuromas and meningiomas.

METHODS Eleven patients with neuromas and 15 patients with meningiomas underwent dynamic contrast-enhanced MR imaging using a short TE FLASH sequence and a bolus injection of Gd-DTPA.

RESULTS There was no significant difference between these tumors in the signal-enhancement increment at the late phase, which corresponds to the signal-enhancement increment between pre- and postcontrast images in conventional spin-echo imaging. However, the signal enhancement at the vascular phase, ie, the phase where the first passage of Gd-DTPA was recognized both in the arteries and veins, was approximately four times as high in meningiomas as in neuromas. The difference was statistically significant. Furthermore, meningiomas had a wider range of early signal enhancement than did neuromas, reflecting the histologic varieties: two angioblastic meningiomas had the highest values, and three fibroblastic the lowest values comparable with those of neuromas, while meningiomas with other subtypes had intermediate values.

CONCLUSIONS The results of this study indicate that the evaluation of early enhancement with dynamic MR imaging is helpful in the differentiation of neuromas and meningiomas, and possibly in the crude prediction of pathologic subtypes of meningiomas." />
<meta name="DC.Contributor" content="K Fujii" />
<meta name="DC.Contributor" content="N Fujita" />
<meta name="DC.Contributor" content="N Hirabuki" />
<meta name="DC.Contributor" content="T Hashimoto" />
<meta name="DC.Contributor" content="T Miura" />
<meta name="DC.Contributor" content="T Kozuka" />
<meta name="article:published_time" content="1992-07-01" />
<meta name="citation_title" content="Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To investigate the role of dynamic MR imaging in the differentiation of neuromas and meningiomas.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Eleven patients with neuromas and 15 patients with meningiomas underwent dynamic contrast-enhanced MR imaging using a short TE FLASH sequence and a bolus injection of Gd-DTPA.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;There was no significant difference between these tumors in the signal-enhancement increment at the late phase, which corresponds to the signal-enhancement increment between pre- and postcontrast images in conventional spin-echo imaging. However, the signal enhancement at the vascular phase, ie, the phase where the first passage of Gd-DTPA was recognized both in the arteries and veins, was approximately four times as high in meningiomas as in neuromas. The difference was statistically significant. Furthermore, meningiomas had a wider range of early signal enhancement than did neuromas, reflecting the histologic varieties: two angioblastic meningiomas had the highest values, and three fibroblastic the lowest values comparable with those of neuromas, while meningiomas with other subtypes had intermediate values.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;The results of this study indicate that the evaluation of early enhancement with dynamic MR imaging is helpful in the differentiation of neuromas and meningiomas, and possibly in the crude prediction of pathologic subtypes of meningiomas.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="K Fujii" />
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<meta name="citation_author" content="N Fujita" />
<meta name="citation_author_institution" content="Department of Radiology, Osaka University Medical School, Japan." />
<meta name="citation_author" content="N Hirabuki" />
<meta name="citation_author_institution" content="Department of Radiology, Osaka University Medical School, Japan." />
<meta name="citation_author" content="T Hashimoto" />
<meta name="citation_author_institution" content="Department of Radiology, Osaka University Medical School, Japan." />
<meta name="citation_author" content="T Miura" />
<meta name="citation_author_institution" content="Department of Radiology, Osaka University Medical School, Japan." />
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<meta name="twitter:title" content="Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging." />
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<meta name="twitter:description" content="PURPOSE To investigate the role of dynamic MR imaging in the differentiation of neuromas and meningiomas.

METHODS Eleven patients with neuromas and 15 patients with meningiomas underwent dynamic contrast-enhanced MR imaging using a short TE FLASH sequence and a bolus injection of Gd-DTPA.

RESULTS There was no significant difference between these tumors in the signal-enhancement increment at the late phase, which corresponds to the signal-enhancement increment between pre- and postcontrast images in conventional spin-echo imaging. However, the signal enhancement at the vascular phase, ie, the phase where the first passage of Gd-DTPA was recognized both in the arteries and veins, was approximately four times as high in meningiomas as in neuromas. The difference was statistically significant. Furthermore, meningiomas had a wider range of early signal enhancement than did neuromas, reflecting the histologic varieties: two angioblastic meningiomas had the highest values, and three fibroblastic the lowest values comparable with those of neuromas, while meningiomas with other subtypes had intermediate values.

CONCLUSIONS The results of this study indicate that the evaluation of early enhancement with dynamic MR imaging is helpful in the differentiation of neuromas and meningiomas, and possibly in the crude prediction of pathologic subtypes of meningiomas." />
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<meta name="og-description" property="og:description" content="PURPOSE To investigate the role of dynamic MR imaging in the differentiation of neuromas and meningiomas.

METHODS Eleven patients with neuromas and 15 patients with meningiomas underwent dynamic contrast-enhanced MR imaging using a short TE FLASH sequence and a bolus injection of Gd-DTPA.

RESULTS There was no significant difference between these tumors in the signal-enhancement increment at the late phase, which corresponds to the signal-enhancement increment between pre- and postcontrast images in conventional spin-echo imaging. However, the signal enhancement at the vascular phase, ie, the phase where the first passage of Gd-DTPA was recognized both in the arteries and veins, was approximately four times as high in meningiomas as in neuromas. The difference was statistically significant. Furthermore, meningiomas had a wider range of early signal enhancement than did neuromas, reflecting the histologic varieties: two angioblastic meningiomas had the highest values, and three fibroblastic the lowest values comparable with those of neuromas, while meningiomas with other subtypes had intermediate values.

CONCLUSIONS The results of this study indicate that the evaluation of early enhancement with dynamic MR imaging is helpful in the differentiation of neuromas and meningiomas, and possibly in the crude prediction of pathologic subtypes of meningiomas." />
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      <h1 class="highwire-cite-title" id="page-title">Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">K Fujii</span>, <span class="highwire-citation-author" data-delta="1">N Fujita</span>, <span class="highwire-citation-author" data-delta="2">N Hirabuki</span>, <span class="highwire-citation-author" data-delta="3">T Hashimoto</span>, <span class="highwire-citation-author" data-delta="4">T Miura</span> and <span class="highwire-citation-author" data-delta="5">T Kozuka</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">July 1992,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">13 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1215-1220; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-5480--61584432697" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">K Fujii </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Radiology, Osaka University Medical School, Japan.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=K%2BFujii%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Fujii%20K&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AK%2BFujii%2B" rel="nofollow" class="" 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 13</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 4 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jul 1992 </div></div>
      
      
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