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<meta name="DC.Title" content="The magnetization transfer effect in cerebral infarction." />
<meta name="DC.Date" content="1994-09-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To estimate the age of cerebral infarcts using magnetization transfer.

METHODS Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area.

RESULTS The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less.

CONCLUSION Magnetization transfer offers the potential to estimate the age of cerebral infarcts." />
<meta name="DC.Contributor" content="J M Prager" />
<meta name="DC.Contributor" content="J D Rosenblum" />
<meta name="DC.Contributor" content="D C Huddle" />
<meta name="DC.Contributor" content="C K Diamond" />
<meta name="DC.Contributor" content="C E Metz" />
<meta name="article:published_time" content="1994-09-01" />
<meta name="citation_title" content="The magnetization transfer effect in cerebral infarction." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To estimate the age of cerebral infarcts using magnetization transfer.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less.&lt;/p&gt;&lt;h3&gt;CONCLUSION&lt;/h3&gt;
&lt;p&gt;Magnetization transfer offers the potential to estimate the age of cerebral infarcts.&lt;/p&gt;" />
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<meta name="citation_author" content="J M Prager" />
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<meta name="citation_author" content="J D Rosenblum" />
<meta name="citation_author_institution" content="Department of Radiology, University of Chicago Hospitals, IL." />
<meta name="citation_author" content="D C Huddle" />
<meta name="citation_author_institution" content="Department of Radiology, University of Chicago Hospitals, IL." />
<meta name="citation_author" content="C K Diamond" />
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<meta name="twitter:title" content="The magnetization transfer effect in cerebral infarction." />
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<meta name="twitter:description" content="PURPOSE To estimate the age of cerebral infarcts using magnetization transfer.

METHODS Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area.

RESULTS The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less.

CONCLUSION Magnetization transfer offers the potential to estimate the age of cerebral infarcts." />
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<meta name="og-description" property="og:description" content="PURPOSE To estimate the age of cerebral infarcts using magnetization transfer.

METHODS Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area.

RESULTS The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less.

CONCLUSION Magnetization transfer offers the potential to estimate the age of cerebral infarcts." />
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      <h1 class="highwire-cite-title" id="page-title">The magnetization transfer effect in cerebral infarction.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">J M Prager</span>, <span class="highwire-citation-author" data-delta="1">J D Rosenblum</span>, <span class="highwire-citation-author" data-delta="2">D C Huddle</span>, <span class="highwire-citation-author" data-delta="3">C K Diamond</span> and <span class="highwire-citation-author" data-delta="4">C E Metz</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1497-1500; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-6135--6425623698" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">J M Prager </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Radiology, University of Chicago Hospitals, IL.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J%2BM%2BPrager%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Prager%20JM&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AJ%2BM%2BPrager%2B" rel="nofollow" class="" 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href="/search/author1%3AD%2BC%2BHuddle%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">C K Diamond </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Radiology, University of Chicago Hospitals, IL.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C%2BK%2BDiamond%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Diamond%20CK&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li 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          <p id="p-1"><strong>PURPOSE</strong> To estimate the age of cerebral infarcts using magnetization transfer.</p>
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          <p id="p-2"><strong>METHODS</strong> Twelve patients with radiographically and clinically documented cortical and subcortical cerebral infarctions underwent MR imaging on a 0.1T magnet. Magnetization transfer contrast images were generated by application of off-resonance pulses to every other repetition time on intermediate-weighted images. The magnetization transfer effect was calculated by obtaining an intensity value in the region of interest within the infarcted area.</p>
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          <p id="p-3"><strong>RESULTS</strong> The data show a pattern in which the magnetization transfer effect decreases as the chronicity of the infarct increases. Infarcts less than 1 week old had an average magnetization transfer effect of 0.35. Those more than 1 week and less than 1 month old average 0.30. Infarcts more than 1 month and specifically those more than 1 year old averaged 0.16 or less.</p>
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          <p id="p-4"><strong>CONCLUSION</strong> Magnetization transfer offers the potential to estimate the age of cerebral infarcts.</p>
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 15</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 8 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Sep 1994 </div></div>
      
      
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      <div class="highwire-cite-title">The magnetization transfer effect in cerebral infarction.</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">J M</span> <span class="nlm-surname">Prager</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">J D</span> <span class="nlm-surname">Rosenblum</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">D C</span> <span class="nlm-surname">Huddle</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">C K</span> <span class="nlm-surname">Diamond</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">C E</span> <span class="nlm-surname">Metz</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 1994, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1497-1500; </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">J M</span> <span class="nlm-surname">Prager</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">J D</span> <span class="nlm-surname">Rosenblum</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">D C</span> <span class="nlm-surname">Huddle</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">C K</span> <span class="nlm-surname">Diamond</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">C E</span> <span class="nlm-surname">Metz</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 1994, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1497-1500; </span></div>
  
  
  
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