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<meta name="DC.Title" content="Extirpation of glioblastomas: MR and CT follow-up of residual tumor and regrowth patterns." />
<meta name="DC.Date" content="1993-01-01" />
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<meta name="DC.Description" content="PURPOSE To optimize the timing of CT and MR after glioblastoma resection and to define the pattern of tumor regrowth.

SUBJECTS AND METHODS Sixty-eight patients with glioblastoma were studied prospectively with CT and MR. The first postoperative scan was obtained between day 1 and day 5; follow-up scans were obtained bimonthly.

RESULTS Residual tumor was shown most reliably on scans obtained shortly after surgery (MR, 77%; CT, 40.5%). After the fourth day up to 3 months postoperatively, surgically induced enhancement prevented recognition of residual tumor. Seventy-five percent of patients with residual tumor shown by early postoperative MR had progressive disease during follow-up, whereas only 36% of patients without evidence of residual tumor had MR signs of progressive disease.

CONCLUSION Early, enhanced, postoperative MR is the radiologic procedure of choice to determine the extent of glioblastoma resection. Gross total tumor resection as determined by early postoperative MR correlates with a prolongation of life." />
<meta name="DC.Contributor" content="M Forsting" />
<meta name="DC.Contributor" content="F K Albert" />
<meta name="DC.Contributor" content="S Kunze" />
<meta name="DC.Contributor" content="H P Adams" />
<meta name="DC.Contributor" content="D Zenner" />
<meta name="DC.Contributor" content="K Sartor" />
<meta name="article:published_time" content="1993-01-01" />
<meta name="citation_title" content="Extirpation of glioblastomas: MR and CT follow-up of residual tumor and regrowth patterns." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To optimize the timing of CT and MR after glioblastoma resection and to define the pattern of tumor regrowth.&lt;/p&gt;&lt;h3&gt;SUBJECTS AND METHODS&lt;/h3&gt;
&lt;p&gt;Sixty-eight patients with glioblastoma were studied prospectively with CT and MR. The first postoperative scan was obtained between day 1 and day 5; follow-up scans were obtained bimonthly.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;Residual tumor was shown most reliably on scans obtained shortly after surgery (MR, 77%; CT, 40.5%). After the fourth day up to 3 months postoperatively, surgically induced enhancement prevented recognition of residual tumor. Seventy-five percent of patients with residual tumor shown by early postoperative MR had progressive disease during follow-up, whereas only 36% of patients without evidence of residual tumor had MR signs of progressive disease.&lt;/p&gt;&lt;h3&gt;CONCLUSION&lt;/h3&gt;
&lt;p&gt;Early, enhanced, postoperative MR is the radiologic procedure of choice to determine the extent of glioblastoma resection. Gross total tumor resection as determined by early postoperative MR correlates with a prolongation of life.&lt;/p&gt;" />
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<meta name="citation_author" content="M Forsting" />
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<meta name="citation_author" content="F K Albert" />
<meta name="citation_author_institution" content="Department of Neuroradiology, University of Heidelberg Medical School, Germany." />
<meta name="citation_author" content="S Kunze" />
<meta name="citation_author_institution" content="Department of Neuroradiology, University of Heidelberg Medical School, Germany." />
<meta name="citation_author" content="H P Adams" />
<meta name="citation_author_institution" content="Department of Neuroradiology, University of Heidelberg Medical School, Germany." />
<meta name="citation_author" content="D Zenner" />
<meta name="citation_author_institution" content="Department of Neuroradiology, University of Heidelberg Medical School, Germany." />
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<meta name="twitter:title" content="Extirpation of glioblastomas: MR and CT follow-up of residual tumor and regrowth patterns." />
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<meta name="twitter:description" content="PURPOSE To optimize the timing of CT and MR after glioblastoma resection and to define the pattern of tumor regrowth.

SUBJECTS AND METHODS Sixty-eight patients with glioblastoma were studied prospectively with CT and MR. The first postoperative scan was obtained between day 1 and day 5; follow-up scans were obtained bimonthly.

RESULTS Residual tumor was shown most reliably on scans obtained shortly after surgery (MR, 77%; CT, 40.5%). After the fourth day up to 3 months postoperatively, surgically induced enhancement prevented recognition of residual tumor. Seventy-five percent of patients with residual tumor shown by early postoperative MR had progressive disease during follow-up, whereas only 36% of patients without evidence of residual tumor had MR signs of progressive disease.

CONCLUSION Early, enhanced, postoperative MR is the radiologic procedure of choice to determine the extent of glioblastoma resection. Gross total tumor resection as determined by early postoperative MR correlates with a prolongation of life." />
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<meta name="og-description" property="og:description" content="PURPOSE To optimize the timing of CT and MR after glioblastoma resection and to define the pattern of tumor regrowth.

SUBJECTS AND METHODS Sixty-eight patients with glioblastoma were studied prospectively with CT and MR. The first postoperative scan was obtained between day 1 and day 5; follow-up scans were obtained bimonthly.

RESULTS Residual tumor was shown most reliably on scans obtained shortly after surgery (MR, 77%; CT, 40.5%). After the fourth day up to 3 months postoperatively, surgically induced enhancement prevented recognition of residual tumor. Seventy-five percent of patients with residual tumor shown by early postoperative MR had progressive disease during follow-up, whereas only 36% of patients without evidence of residual tumor had MR signs of progressive disease.

CONCLUSION Early, enhanced, postoperative MR is the radiologic procedure of choice to determine the extent of glioblastoma resection. Gross total tumor resection as determined by early postoperative MR correlates with a prolongation of life." />
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      <h1 class="highwire-cite-title" id="page-title">Extirpation of glioblastomas: MR and CT follow-up of residual tumor and regrowth patterns.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">M Forsting</span>, <span class="highwire-citation-author" data-delta="1">F K Albert</span>, <span class="highwire-citation-author" data-delta="2">S Kunze</span>, <span class="highwire-citation-author" data-delta="3">H P Adams</span>, <span class="highwire-citation-author" data-delta="4">D Zenner</span> and <span class="highwire-citation-author" data-delta="5">K Sartor</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">January 1993,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">14 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">77-87; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-5679--8768994343" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">M Forsting </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Neuroradiology, University of Heidelberg Medical School, Germany.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M%2BForsting%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Forsting%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM%2BForsting%2B" rel="nofollow" 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 14</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 1 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jan 1993 </div></div>
      
      
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 1993, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">14 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">77-87; </span></div>
  
  
  
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