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<meta name="DC.Title" content="Detection of recurrent thyroid cancer: MR versus thallium-201 scintigraphy." />
<meta name="DC.Date" content="1993-09-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To compare MR with thallium-201 scintigraphy in the follow-up of patients who have undergone thyroidectomy and modified radical neck dissection for differentiated thyroid cancer.

METHODS Both MR imaging and 201Tl scintigraphy were performed in 39 patients after surgery for differentiated thyroid cancer. Ten patients did not have recurrence; 29 patients had 51 recurrent tumors in the neck and mediastinum.

RESULTS Among 51 tumor sites, 39 sites of recurrence were detected by MR and 24 were detected by 201Tl scintigraphy. The true-positive rate, false-negative rate, true-negative rate, and false-positive rate in detecting recurrent thyroid cancer were 76.5, 23.5, 100, and 0%, respectively, for MR and 47.1, 52.9, 100, and 0%, respectively, for 201Tl scintigraphy. MR was more sensitive than 201Tl scintigraphy in detecting recurrent tumors (especially small metastatic nodes). On T2-weighted MR images, recurrent tumor was characterized by high signal intensity. Scarring in the postoperative thyroid bed was characterized by low signal intensity on both T1- and T2-weighted images. Abnormal accumulation of 201Tl in the postoperative thyroid bed was not observed.

CONCLUSIONS Although both MR images and 201Tl scintigraphy were effective in distinguishing recurrent tumor from postoperative fibrous tissue, MR images were more sensitive than 201Tl scintigraphy in detecting recurrent tumors. These results suggest that MR imaging is more useful than 201Tl scintigraphy in the follow-up evaluation of patients after neck surgery for differentiated thyroid cancer." />
<meta name="DC.Contributor" content="T Ohnishi" />
<meta name="DC.Contributor" content="S Noguchi" />
<meta name="DC.Contributor" content="N Murakami" />
<meta name="DC.Contributor" content="S Jinnouchi" />
<meta name="DC.Contributor" content="H Hoshi" />
<meta name="DC.Contributor" content="S Futami" />
<meta name="DC.Contributor" content="K Watanabe" />
<meta name="article:published_time" content="1993-09-01" />
<meta name="citation_title" content="Detection of recurrent thyroid cancer: MR versus thallium-201 scintigraphy." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To compare MR with thallium-201 scintigraphy in the follow-up of patients who have undergone thyroidectomy and modified radical neck dissection for differentiated thyroid cancer.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Both MR imaging and 201Tl scintigraphy were performed in 39 patients after surgery for differentiated thyroid cancer. Ten patients did not have recurrence; 29 patients had 51 recurrent tumors in the neck and mediastinum.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;Among 51 tumor sites, 39 sites of recurrence were detected by MR and 24 were detected by 201Tl scintigraphy. The true-positive rate, false-negative rate, true-negative rate, and false-positive rate in detecting recurrent thyroid cancer were 76.5, 23.5, 100, and 0%, respectively, for MR and 47.1, 52.9, 100, and 0%, respectively, for 201Tl scintigraphy. MR was more sensitive than 201Tl scintigraphy in detecting recurrent tumors (especially small metastatic nodes). On T2-weighted MR images, recurrent tumor was characterized by high signal intensity. Scarring in the postoperative thyroid bed was characterized by low signal intensity on both T1- and T2-weighted images. Abnormal accumulation of 201Tl in the postoperative thyroid bed was not observed.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;Although both MR images and 201Tl scintigraphy were effective in distinguishing recurrent tumor from postoperative fibrous tissue, MR images were more sensitive than 201Tl scintigraphy in detecting recurrent tumors. These results suggest that MR imaging is more useful than 201Tl scintigraphy in the follow-up evaluation of patients after neck surgery for differentiated thyroid cancer.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="1993/09/01" />
<meta name="citation_mjid" content="ajnr;14/5/1051" />
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<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
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<meta name="citation_article_type" content="Abstract" />
<meta name="citation_firstpage" content="1051" />
<meta name="citation_lastpage" content="1057" />
<meta name="citation_author" content="T Ohnishi" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="S Noguchi" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="N Murakami" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="S Jinnouchi" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="H Hoshi" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="S Futami" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="citation_author" content="K Watanabe" />
<meta name="citation_author_institution" content="Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan." />
<meta name="twitter:title" content="Detection of recurrent thyroid cancer: MR versus thallium-201 scintigraphy." />
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<meta name="twitter:description" content="PURPOSE To compare MR with thallium-201 scintigraphy in the follow-up of patients who have undergone thyroidectomy and modified radical neck dissection for differentiated thyroid cancer.

METHODS Both MR imaging and 201Tl scintigraphy were performed in 39 patients after surgery for differentiated thyroid cancer. Ten patients did not have recurrence; 29 patients had 51 recurrent tumors in the neck and mediastinum.

RESULTS Among 51 tumor sites, 39 sites of recurrence were detected by MR and 24 were detected by 201Tl scintigraphy. The true-positive rate, false-negative rate, true-negative rate, and false-positive rate in detecting recurrent thyroid cancer were 76.5, 23.5, 100, and 0%, respectively, for MR and 47.1, 52.9, 100, and 0%, respectively, for 201Tl scintigraphy. MR was more sensitive than 201Tl scintigraphy in detecting recurrent tumors (especially small metastatic nodes). On T2-weighted MR images, recurrent tumor was characterized by high signal intensity. Scarring in the postoperative thyroid bed was characterized by low signal intensity on both T1- and T2-weighted images. Abnormal accumulation of 201Tl in the postoperative thyroid bed was not observed.

CONCLUSIONS Although both MR images and 201Tl scintigraphy were effective in distinguishing recurrent tumor from postoperative fibrous tissue, MR images were more sensitive than 201Tl scintigraphy in detecting recurrent tumors. These results suggest that MR imaging is more useful than 201Tl scintigraphy in the follow-up evaluation of patients after neck surgery for differentiated thyroid cancer." />
<meta name="og-title" property="og:title" content="Detection of recurrent thyroid cancer: MR versus thallium-201 scintigraphy." />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="PURPOSE To compare MR with thallium-201 scintigraphy in the follow-up of patients who have undergone thyroidectomy and modified radical neck dissection for differentiated thyroid cancer.

METHODS Both MR imaging and 201Tl scintigraphy were performed in 39 patients after surgery for differentiated thyroid cancer. Ten patients did not have recurrence; 29 patients had 51 recurrent tumors in the neck and mediastinum.

RESULTS Among 51 tumor sites, 39 sites of recurrence were detected by MR and 24 were detected by 201Tl scintigraphy. The true-positive rate, false-negative rate, true-negative rate, and false-positive rate in detecting recurrent thyroid cancer were 76.5, 23.5, 100, and 0%, respectively, for MR and 47.1, 52.9, 100, and 0%, respectively, for 201Tl scintigraphy. MR was more sensitive than 201Tl scintigraphy in detecting recurrent tumors (especially small metastatic nodes). On T2-weighted MR images, recurrent tumor was characterized by high signal intensity. Scarring in the postoperative thyroid bed was characterized by low signal intensity on both T1- and T2-weighted images. Abnormal accumulation of 201Tl in the postoperative thyroid bed was not observed.

CONCLUSIONS Although both MR images and 201Tl scintigraphy were effective in distinguishing recurrent tumor from postoperative fibrous tissue, MR images were more sensitive than 201Tl scintigraphy in detecting recurrent tumors. These results suggest that MR imaging is more useful than 201Tl scintigraphy in the follow-up evaluation of patients after neck surgery for differentiated thyroid cancer." />
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      <h1 class="highwire-cite-title" id="page-title">Detection of recurrent thyroid cancer: MR versus thallium-201 scintigraphy.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">T Ohnishi</span>, <span class="highwire-citation-author" data-delta="1">S Noguchi</span>, <span class="highwire-citation-author" data-delta="2">N Murakami</span>, <span class="highwire-citation-author" data-delta="3">S Jinnouchi</span>, <span class="highwire-citation-author" data-delta="4">H Hoshi</span>, <span class="highwire-citation-author" data-delta="5">S Futami</span> and <span class="highwire-citation-author" data-delta="6">K Watanabe</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 1993,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">14 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1051-1057; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-5865--61727027576" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">T Ohnishi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=T%2BOhnishi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Ohnishi%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AT%2BOhnishi%2B" rel="nofollow" class="" 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 14</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 5 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Sep 1993 </div></div>
      
      
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