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<meta name="DC.Title" content="A mechanically detachable coil for the treatment of aneurysms and occlusion of blood vessels." />
<meta name="DC.Date" content="1994-05-01" />
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<meta name="DC.Description" content="PURPOSE To evaluate mechanically detachable coil designs capable of controlled and instantaneous release within an aneurysm or vascular space.

METHODS Three mechanically detachable coil designs, clamped ball, looped ribbon, and interlocking cylinder, were evaluated using in vitro and in vivo testing to study reliability of coil release, retractability, and coil behavior in a microcatheters. In vitro tests were performed using a glass side-wall aneurysm model and conventional microcatheters. In vivo experiments in rabbits included aneurysm models (side-wall and bifurcation) and arterial occlusions (carotid and renal).

RESULTS All three designs deployed coils easily and were able to retract coils after partial deployment. Motion was seen in previously released coils and in the catheter when using the clamped ball and looped ribbon designs. The interlocking cylinder design did not cause similar motion. When compared with the other two designs, the interlocking cylinder had significantly greater separation forces between coil pusher and coil while in the catheter. Frictional forces within the catheter were lower for the interlocking cylinder mechanically detachable coil design than for a commercially available conventional coil and coil pusher system. During in vivo testing, the mechanically detachable coil design operated smoothly in the catheter, providing good release and retraction in aneurysms and straight vessels.

CONCLUSION The interlocking cylinder mechanically detachable coil design is superior to the other two tested designs. The mechanically detachable coil was reliably delivered and detached in in vivo testing for the treatment of aneurysms and for the occlusion of blood vessels." />
<meta name="DC.Contributor" content="M P Marks" />
<meta name="DC.Contributor" content="H Chee" />
<meta name="DC.Contributor" content="R P Liddell" />
<meta name="DC.Contributor" content="G K Steinberg" />
<meta name="DC.Contributor" content="N Panahian" />
<meta name="DC.Contributor" content="B Lane" />
<meta name="article:published_time" content="1994-05-01" />
<meta name="citation_title" content="A mechanically detachable coil for the treatment of aneurysms and occlusion of blood vessels." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To evaluate mechanically detachable coil designs capable of controlled and instantaneous release within an aneurysm or vascular space.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Three mechanically detachable coil designs, clamped ball, looped ribbon, and interlocking cylinder, were evaluated using in vitro and in vivo testing to study reliability of coil release, retractability, and coil behavior in a microcatheters. In vitro tests were performed using a glass side-wall aneurysm model and conventional microcatheters. In vivo experiments in rabbits included aneurysm models (side-wall and bifurcation) and arterial occlusions (carotid and renal).&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;All three designs deployed coils easily and were able to retract coils after partial deployment. Motion was seen in previously released coils and in the catheter when using the clamped ball and looped ribbon designs. The interlocking cylinder design did not cause similar motion. When compared with the other two designs, the interlocking cylinder had significantly greater separation forces between coil pusher and coil while in the catheter. Frictional forces within the catheter were lower for the interlocking cylinder mechanically detachable coil design than for a commercially available conventional coil and coil pusher system. During in vivo testing, the mechanically detachable coil design operated smoothly in the catheter, providing good release and retraction in aneurysms and straight vessels.&lt;/p&gt;&lt;h3&gt;CONCLUSION&lt;/h3&gt;
&lt;p&gt;The interlocking cylinder mechanically detachable coil design is superior to the other two tested designs. The mechanically detachable coil was reliably delivered and detached in in vivo testing for the treatment of aneurysms and for the occlusion of blood vessels.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="1994/05/01" />
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<meta name="citation_article_type" content="Abstract" />
<meta name="citation_firstpage" content="821" />
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<meta name="citation_author" content="M P Marks" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="citation_author" content="H Chee" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="citation_author" content="R P Liddell" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="citation_author" content="G K Steinberg" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="citation_author" content="N Panahian" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="citation_author" content="B Lane" />
<meta name="citation_author_institution" content="Department of Radiology, Stanford University Medical Center, CA 94305-5105." />
<meta name="twitter:title" content="A mechanically detachable coil for the treatment of aneurysms and occlusion of blood vessels." />
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<meta name="twitter:description" content="PURPOSE To evaluate mechanically detachable coil designs capable of controlled and instantaneous release within an aneurysm or vascular space.

METHODS Three mechanically detachable coil designs, clamped ball, looped ribbon, and interlocking cylinder, were evaluated using in vitro and in vivo testing to study reliability of coil release, retractability, and coil behavior in a microcatheters. In vitro tests were performed using a glass side-wall aneurysm model and conventional microcatheters. In vivo experiments in rabbits included aneurysm models (side-wall and bifurcation) and arterial occlusions (carotid and renal).

RESULTS All three designs deployed coils easily and were able to retract coils after partial deployment. Motion was seen in previously released coils and in the catheter when using the clamped ball and looped ribbon designs. The interlocking cylinder design did not cause similar motion. When compared with the other two designs, the interlocking cylinder had significantly greater separation forces between coil pusher and coil while in the catheter. Frictional forces within the catheter were lower for the interlocking cylinder mechanically detachable coil design than for a commercially available conventional coil and coil pusher system. During in vivo testing, the mechanically detachable coil design operated smoothly in the catheter, providing good release and retraction in aneurysms and straight vessels.

CONCLUSION The interlocking cylinder mechanically detachable coil design is superior to the other two tested designs. The mechanically detachable coil was reliably delivered and detached in in vivo testing for the treatment of aneurysms and for the occlusion of blood vessels." />
<meta name="og-title" property="og:title" content="A mechanically detachable coil for the treatment of aneurysms and occlusion of blood vessels." />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/15/5/821" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="PURPOSE To evaluate mechanically detachable coil designs capable of controlled and instantaneous release within an aneurysm or vascular space.

METHODS Three mechanically detachable coil designs, clamped ball, looped ribbon, and interlocking cylinder, were evaluated using in vitro and in vivo testing to study reliability of coil release, retractability, and coil behavior in a microcatheters. In vitro tests were performed using a glass side-wall aneurysm model and conventional microcatheters. In vivo experiments in rabbits included aneurysm models (side-wall and bifurcation) and arterial occlusions (carotid and renal).

RESULTS All three designs deployed coils easily and were able to retract coils after partial deployment. Motion was seen in previously released coils and in the catheter when using the clamped ball and looped ribbon designs. The interlocking cylinder design did not cause similar motion. When compared with the other two designs, the interlocking cylinder had significantly greater separation forces between coil pusher and coil while in the catheter. Frictional forces within the catheter were lower for the interlocking cylinder mechanically detachable coil design than for a commercially available conventional coil and coil pusher system. During in vivo testing, the mechanically detachable coil design operated smoothly in the catheter, providing good release and retraction in aneurysms and straight vessels.

CONCLUSION The interlocking cylinder mechanically detachable coil design is superior to the other two tested designs. The mechanically detachable coil was reliably delivered and detached in in vivo testing for the treatment of aneurysms and for the occlusion of blood vessels." />
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      <h1 class="highwire-cite-title" id="page-title">A mechanically detachable coil for the treatment of aneurysms and occlusion of blood vessels.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">M P Marks</span>, <span class="highwire-citation-author" data-delta="1">H Chee</span>, <span class="highwire-citation-author" data-delta="2">R P Liddell</span>, <span class="highwire-citation-author" data-delta="3">G K Steinberg</span>, <span class="highwire-citation-author" data-delta="4">N Panahian</span> and <span class="highwire-citation-author" data-delta="5">B Lane</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">821-827; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-6030--8618446502" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">M P Marks </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Radiology, Stanford University Medical Center, CA 94305-5105.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M%2BP%2BMarks%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Marks%20MP&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM%2BP%2BMarks%2B" rel="nofollow" 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          <a href="/content/15/5" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">American Journal of Neuroradiology</span></a>      
      
        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 15</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 5 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 May 1994 </div></div>
      
      
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