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<meta name="DC.Title" content="Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography." />
<meta name="DC.Date" content="1994-05-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="Copyright © American Society of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To determine whether the method of delivery of gadolinium can alter optimal small-vessel detail in MR angiography.

METHODS Six healthy volunteers were studied with MR angiography using both a constant infusion and a bolus method of contrast administration to a total dose of 0.1 mmol/kg. Both three-dimensional time-of-flight and 3-D phase-contrast techniques were used.

RESULTS Constant infusion did not prove superior to bolus administration of contrast. With both techniques, gadolinium enhancement uniformly improved visualization of small vessels. Delay from the time of contrast administration to scan acquisition decreased vessel enhancement.

CONCLUSIONS Bolus administration of gadolinium is sufficient to improve small vessel visualization with MR angiography. When a series of contrast-enhanced images is to be obtained, MR angiographic sequences should be obtained first." />
<meta name="DC.Contributor" content="G Sze" />
<meta name="DC.Contributor" content="S N Goldberg" />
<meta name="DC.Contributor" content="Y Kawamura" />
<meta name="article:published_time" content="1994-05-01" />
<meta name="citation_title" content="Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To determine whether the method of delivery of gadolinium can alter optimal small-vessel detail in MR angiography.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Six healthy volunteers were studied with MR angiography using both a constant infusion and a bolus method of contrast administration to a total dose of 0.1 mmol/kg. Both three-dimensional time-of-flight and 3-D phase-contrast techniques were used.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;Constant infusion did not prove superior to bolus administration of contrast. With both techniques, gadolinium enhancement uniformly improved visualization of small vessels. Delay from the time of contrast administration to scan acquisition decreased vessel enhancement.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;Bolus administration of gadolinium is sufficient to improve small vessel visualization with MR angiography. When a series of contrast-enhanced images is to be obtained, MR angiographic sequences should be obtained first.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="G Sze" />
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<meta name="citation_author" content="S N Goldberg" />
<meta name="citation_author_institution" content="Yale University School of Medicine, Department of Radiology, New Haven, CT 06510." />
<meta name="citation_author" content="Y Kawamura" />
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<meta name="twitter:title" content="Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography." />
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<meta name="twitter:description" content="PURPOSE To determine whether the method of delivery of gadolinium can alter optimal small-vessel detail in MR angiography.

METHODS Six healthy volunteers were studied with MR angiography using both a constant infusion and a bolus method of contrast administration to a total dose of 0.1 mmol/kg. Both three-dimensional time-of-flight and 3-D phase-contrast techniques were used.

RESULTS Constant infusion did not prove superior to bolus administration of contrast. With both techniques, gadolinium enhancement uniformly improved visualization of small vessels. Delay from the time of contrast administration to scan acquisition decreased vessel enhancement.

CONCLUSIONS Bolus administration of gadolinium is sufficient to improve small vessel visualization with MR angiography. When a series of contrast-enhanced images is to be obtained, MR angiographic sequences should be obtained first." />
<meta name="og-title" property="og:title" content="Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography." />
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<meta name="og-description" property="og:description" content="PURPOSE To determine whether the method of delivery of gadolinium can alter optimal small-vessel detail in MR angiography.

METHODS Six healthy volunteers were studied with MR angiography using both a constant infusion and a bolus method of contrast administration to a total dose of 0.1 mmol/kg. Both three-dimensional time-of-flight and 3-D phase-contrast techniques were used.

RESULTS Constant infusion did not prove superior to bolus administration of contrast. With both techniques, gadolinium enhancement uniformly improved visualization of small vessels. Delay from the time of contrast administration to scan acquisition decreased vessel enhancement.

CONCLUSIONS Bolus administration of gadolinium is sufficient to improve small vessel visualization with MR angiography. When a series of contrast-enhanced images is to be obtained, MR angiographic sequences should be obtained first." />
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      <h1 class="highwire-cite-title" id="page-title">Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">G Sze</span>, <span class="highwire-citation-author" data-delta="1">S N Goldberg</span> and <span class="highwire-citation-author" data-delta="2">Y Kawamura</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">909-912; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-6034--67814964" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">G Sze </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Yale University School of Medicine, Department of Radiology, New Haven, CT 06510.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G%2BSze%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sze%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AG%2BSze%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">S N Goldberg </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Yale University School of Medicine, Department of Radiology, New Haven, CT 06510.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S%2BN%2BGoldberg%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Goldberg%20SN&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AS%2BN%2BGoldberg%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">Y Kawamura </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Yale University School of Medicine, Department of Radiology, New Haven, CT 06510.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y%2BKawamura%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Kawamura%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AY%2BKawamura%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div></div></div>  </div>

  
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          <p id="p-1"><strong>PURPOSE</strong> To determine whether the method of delivery of gadolinium can alter optimal small-vessel detail in MR angiography.</p>
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          <p id="p-2"><strong>METHODS</strong> Six healthy volunteers were studied with MR angiography using both a constant infusion and a bolus method of contrast administration to a total dose of 0.1 mmol/kg. Both three-dimensional time-of-flight and 3-D phase-contrast techniques were used.</p>
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          <p id="p-3"><strong>RESULTS</strong> Constant infusion did not prove superior to bolus administration of contrast. With both techniques, gadolinium enhancement uniformly improved visualization of small vessels. Delay from the time of contrast administration to scan acquisition decreased vessel enhancement.</p>
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          <p id="p-4"><strong>CONCLUSIONS</strong> Bolus administration of gadolinium is sufficient to improve small vessel visualization with MR angiography. When a series of contrast-enhanced images is to be obtained, MR angiographic sequences should be obtained first.</p>
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      <div class="highwire-cite-title">Comparison of bolus and constant infusion methods of gadolinium administration in MR angiography.</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">G</span> <span class="nlm-surname">Sze</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S N</span> <span class="nlm-surname">Goldberg</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Y</span> <span class="nlm-surname">Kawamura</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 1994, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">909-912; </span></div>
  
  
  
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