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<meta name="DC.Title" content="Cerebral infarction in patients with AIDS." />
<meta name="DC.Date" content="1997-09-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To establish the frequency, distribution, and pathogenesis of cerebral infarction as confirmed with MR imaging in a cohort of patients with acquired immunodeficiency syndrome (AIDS).

METHODS We reviewed all (71) abnormal cranial MR studies obtained at our institution in human immunodeficiency virus (HIV)-positive patients over a 2-year period and recorded the number and distribution of ischemic lesions, any associated abnormalities, and the MR angiographic findings, where available. Patients' charts were studied for relevant clinical data, biochemical and culture results, and potential etiologic factors.

RESULTS Twenty-two infarcts were seen in 13 of the 71 patients. Of these 22, the basal ganglia area was affected in 15, the middle cerebral artery territory in two, and the vertebrobasilar territory in five. Five patients had concomitant evidence of infection, six others used cocaine or were intravenous drug abusers. MR angiography was performed in eight patients; two of these had multiple lesions consistent with vasculitis, two had isolated lesions that corresponded with their parenchymal infarct, and four had normal findings.

CONCLUSIONS The frequency of infarction was 18%, higher than previously reported. The pathogenesis of infarction was multifactorial. Underlying infectious causes were identified in 39% of patients. Two patients had an idiopathic vasculitis." />
<meta name="DC.Contributor" content="A R Gillams" />
<meta name="DC.Contributor" content="E Allen" />
<meta name="DC.Contributor" content="K Hrieb" />
<meta name="DC.Contributor" content="N Venna" />
<meta name="DC.Contributor" content="D Craven" />
<meta name="DC.Contributor" content="A P Carter" />
<meta name="article:published_time" content="1997-09-01" />
<meta name="citation_title" content="Cerebral infarction in patients with AIDS." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To establish the frequency, distribution, and pathogenesis of cerebral infarction as confirmed with MR imaging in a cohort of patients with acquired immunodeficiency syndrome (AIDS).&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;We reviewed all (71) abnormal cranial MR studies obtained at our institution in human immunodeficiency virus (HIV)-positive patients over a 2-year period and recorded the number and distribution of ischemic lesions, any associated abnormalities, and the MR angiographic findings, where available. Patients9 charts were studied for relevant clinical data, biochemical and culture results, and potential etiologic factors.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;Twenty-two infarcts were seen in 13 of the 71 patients. Of these 22, the basal ganglia area was affected in 15, the middle cerebral artery territory in two, and the vertebrobasilar territory in five. Five patients had concomitant evidence of infection, six others used cocaine or were intravenous drug abusers. MR angiography was performed in eight patients; two of these had multiple lesions consistent with vasculitis, two had isolated lesions that corresponded with their parenchymal infarct, and four had normal findings.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;The frequency of infarction was 18%, higher than previously reported. The pathogenesis of infarction was multifactorial. Underlying infectious causes were identified in 39% of patients. Two patients had an idiopathic vasculitis.&lt;/p&gt;" />
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<meta name="citation_author" content="A R Gillams" />
<meta name="citation_author" content="E Allen" />
<meta name="citation_author" content="K Hrieb" />
<meta name="citation_author" content="N Venna" />
<meta name="citation_author" content="D Craven" />
<meta name="citation_author" content="A P Carter" />
<meta name="twitter:title" content="Cerebral infarction in patients with AIDS." />
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<meta name="twitter:description" content="PURPOSE To establish the frequency, distribution, and pathogenesis of cerebral infarction as confirmed with MR imaging in a cohort of patients with acquired immunodeficiency syndrome (AIDS).

METHODS We reviewed all (71) abnormal cranial MR studies obtained at our institution in human immunodeficiency virus (HIV)-positive patients over a 2-year period and recorded the number and distribution of ischemic lesions, any associated abnormalities, and the MR angiographic findings, where available. Patients' charts were studied for relevant clinical data, biochemical and culture results, and potential etiologic factors.

RESULTS Twenty-two infarcts were seen in 13 of the 71 patients. Of these 22, the basal ganglia area was affected in 15, the middle cerebral artery territory in two, and the vertebrobasilar territory in five. Five patients had concomitant evidence of infection, six others used cocaine or were intravenous drug abusers. MR angiography was performed in eight patients; two of these had multiple lesions consistent with vasculitis, two had isolated lesions that corresponded with their parenchymal infarct, and four had normal findings.

CONCLUSIONS The frequency of infarction was 18%, higher than previously reported. The pathogenesis of infarction was multifactorial. Underlying infectious causes were identified in 39% of patients. Two patients had an idiopathic vasculitis." />
<meta name="og-title" property="og:title" content="Cerebral infarction in patients with AIDS." />
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<meta name="og-description" property="og:description" content="PURPOSE To establish the frequency, distribution, and pathogenesis of cerebral infarction as confirmed with MR imaging in a cohort of patients with acquired immunodeficiency syndrome (AIDS).

METHODS We reviewed all (71) abnormal cranial MR studies obtained at our institution in human immunodeficiency virus (HIV)-positive patients over a 2-year period and recorded the number and distribution of ischemic lesions, any associated abnormalities, and the MR angiographic findings, where available. Patients' charts were studied for relevant clinical data, biochemical and culture results, and potential etiologic factors.

RESULTS Twenty-two infarcts were seen in 13 of the 71 patients. Of these 22, the basal ganglia area was affected in 15, the middle cerebral artery territory in two, and the vertebrobasilar territory in five. Five patients had concomitant evidence of infection, six others used cocaine or were intravenous drug abusers. MR angiography was performed in eight patients; two of these had multiple lesions consistent with vasculitis, two had isolated lesions that corresponded with their parenchymal infarct, and four had normal findings.

CONCLUSIONS The frequency of infarction was 18%, higher than previously reported. The pathogenesis of infarction was multifactorial. Underlying infectious causes were identified in 39% of patients. Two patients had an idiopathic vasculitis." />
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      <h1 class="highwire-cite-title" id="page-title">Cerebral infarction in patients with AIDS.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">A R Gillams</span>, <span class="highwire-citation-author" data-delta="1">E Allen</span>, <span class="highwire-citation-author" data-delta="2">K Hrieb</span>, <span class="highwire-citation-author" data-delta="3">N Venna</span>, <span class="highwire-citation-author" data-delta="4">D Craven</span> and <span class="highwire-citation-author" data-delta="5">A P Carter</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 1997,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">18 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1581-1585; </span></div>
  
  
  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 18</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 8 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Sep 1997 </div></div>
      
      
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">A R</span> <span class="nlm-surname">Gillams</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">E</span> <span class="nlm-surname">Allen</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">K</span> <span class="nlm-surname">Hrieb</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">N</span> <span class="nlm-surname">Venna</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">D</span> <span class="nlm-surname">Craven</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">A P</span> <span class="nlm-surname">Carter</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 1997, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">18 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1581-1585; </span></div>
  
  
  
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