Research ArticleBRAIN
Discrimination between Neoplastic and Nonneoplastic Brain Lesions by Use of Proton MR Spectroscopy: The Limits of Accuracy with a Logistic Regression Model
Jennifer Butzen, Robert Prost, Veerappu Chetty, Kathleen Donahue, Ronald Neppl, William Bowen, Shi-Jiang Li, Victor Haughton, Leighton Mark, Thomas Kim, Wade Mueller, Glenn Meyer, Hendrikus Krouwer and Scott Rand
American Journal of Neuroradiology August 2000, 21 (7) 1213-1219;
Jennifer Butzen
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Robert Prost
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Veerappu Chetty
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Kathleen Donahue
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Ronald Neppl
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
William Bowen
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Shi-Jiang Li
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Victor Haughton
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Leighton Mark
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Thomas Kim
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Wade Mueller
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Glenn Meyer
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Hendrikus Krouwer
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.
Scott Rand
a From the Departments of Radiology, Biophysics (J.B., R.P., V.C., K.D., R.N., W.B., S-J.L., V.H., L.M., T.K., W.M., G.M., H.K., S.R.), Neurosurgery (W.M., G.M.), and Neurology (H.K.), Medical College of Wisconsin, Milwaukee, Wisconsin; the Department of Family Practice (V.K.C.), University of Illinois College of Medicine at Rockford, Rockford, Illinois; Department of Radiology (V.H.), University of Wisconsin Hospitals and Clinics, Madison, Wisconsin; and the Department of Radiology (T.K.), University of Washington Medical Center, Seattle, Washington.

References
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- ↵Prost R, Haughton V, Li S-J. Brain Tumors: localized H-1 MR spectroscopy at 0.5 T. Radiology 1997;204:235-238
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- ↵Krouwer HGJ, Kim TA, Rand SD, et al. Single-voxel proton MR spectroscopy of nonneoplastic brain lesions suggestive of a neoplasm. AJNR Am J Neuroradiol 1998;19:1695-1703
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Discrimination between Neoplastic and Nonneoplastic Brain Lesions by Use of Proton MR Spectroscopy: The Limits of Accuracy with a Logistic Regression Model
Jennifer Butzen, Robert Prost, Veerappu Chetty, Kathleen Donahue, Ronald Neppl, William Bowen, Shi-Jiang Li, Victor Haughton, Leighton Mark, Thomas Kim, Wade Mueller, Glenn Meyer, Hendrikus Krouwer, Scott Rand
American Journal of Neuroradiology Aug 2000, 21 (7) 1213-1219;
Discrimination between Neoplastic and Nonneoplastic Brain Lesions by Use of Proton MR Spectroscopy: The Limits of Accuracy with a Logistic Regression Model
Jennifer Butzen, Robert Prost, Veerappu Chetty, Kathleen Donahue, Ronald Neppl, William Bowen, Shi-Jiang Li, Victor Haughton, Leighton Mark, Thomas Kim, Wade Mueller, Glenn Meyer, Hendrikus Krouwer, Scott Rand
American Journal of Neuroradiology Aug 2000, 21 (7) 1213-1219;
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