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    An Automated Technique for Measuring Hippocampal Volumes from MR Imaging Studies | American Journal of Neuroradiology  
    

















    



























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticleBRAIN

  
      

  
      
An Automated Technique for Measuring Hippocampal Volumes from MR Imaging Studies
  
    	
Karen M. Gosche, James A. Mortimer, Charles D. Smith, William R. Markesbery and David A. Snowdon

  
    	
American Journal of Neuroradiology October 2001,  22 (9) 1686-1689; 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. Convit A, De Leon MJ, Tarshish C,  et al.  Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol Aging 1997;18:131-138
    CrossRefPubMedWeb of Science
  2. Convit A, de Asis J, de Leon MJ, Tarshish CY, De Santi S, Rusinek H.  Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease. Neurobiol Aging 2000;21:19-26
    PubMedWeb of Science
  3. Jack CR Jr, Petersen RC, Xu YC,   et al.  Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 1997;49:786-794
    Abstract/FREE Full Text
  4. Kaye JA, Swihart T, Howieson D,  et al.  Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia. Neurology 1997;48:1297-1304
    Abstract/FREE Full Text
  5. Killiany RJ, Gomez-Isla T, Moss M,  et al.  Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol 2000;47:430-439
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    Honeycutt NA, Smith CD.  Hippocampal volume measurements using magnetic resonance imaging in normal young adults. J Neuroimaging 1995;5:95-100
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    Snowdon DA, Kemper SJ, Mortimer JA, Greiner LH, Wekstein DR, Markesbery WR.  Linguistic ability in early life and cognitive function and Alzheimer's disease in late life: findings from the Nun Study. JAMA 1996;275:528-532
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    Braak H, Braak E.  Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259
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    Gosche KM, Velthuizen RP, Murtagh FR,  et al.  Automated quantification of brain magnetic resonance image hyperintensities using hybrid clustering and knowledge-based methods. Int J Imaging Syst Technol 1999;10:287-293
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    Fox N.  Magnetic resonance imaging in Alzheimer's disease: from diagnosis to measuring therapeutic effect. Alzheimer's Reports 1999;2:5-12
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    Bobinski M, Wegiel J, Wisniewski HM,  et al.  Neurofibrillary pathology: correlation with hippocampal formation atrophy in Alzheimer's disease. Neurobiol Aging 1996;17:909-919
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  12. Bobinski M, de Leon MJ, Tarnawski M,  et al.  Neuronal and volume loss in CA1 of the hippocampal formation uniquely predicts duration and severity of Alzheimer's disease. Brain Res 1998;805:267-269
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An Automated Technique for Measuring Hippocampal Volumes from MR Imaging Studies
  
    	
Karen M. Gosche, James A. Mortimer, Charles D. Smith, William R. Markesbery, David A. Snowdon

  
    	
American Journal of Neuroradiology Oct 2001, 22 (9) 1686-1689; 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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