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<meta name="DC.Title" content="Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging" />
<meta name="DC.Date" content="2002-06-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: In patients with clinical symptoms suggestive of a retrocochlear disorder, contrast-enhanced T1-weighted spin-echo (SE) high-field-strength MR imaging is considered the criterion standard in assessing vestibular schwannoma. However, only 10–20% of its findings are pathologic. Our purpose was to prospectively compare the performance of low-field-strength MR imaging in screening for retrocochlear disorders, with high-field-strength MR imaging as the criterion standard.

METHODS: A total of 287 patients with suspected retrocochlear disease underwent axial 1.5-T MR imaging with a T1-weighted SE sequence before and after contrast enhancement and with a high-resolution T2-weighted construction interference in steady state sequence. At immediate follow-up, the same patients underwent axial 0.2-T T1-weighted SE imaging without additional contrast enhancement. Results were classified as negative, positive, or uncertain and were analyzed in light of the patients’ clinical symptoms.

RESULTS: MR imaging at 1.5 T depicted 63 disorders (21.95%), including 53 schwannomas, three other tumors, and seven other disorders (ie, gadolinium-enhancing inner ear, facial nerve, or meninges). MR imaging at 0.2 T showed evidence of 58 disorders; five disorders were not detected, although all schwannomas and other tumors were seen, including those smaller than 2 mm, and only two (28.6%) of the other disorders were detected. When correlated with clinical data, results showed that the five undetected disorders occurred in patients with unusual clinical signs.

CONCLUSION: MR imaging at 0.2 T provided high sensitivity in detecting vestibular schwannoma of the internal auditory canal or cerebellopontine angle; it can be used for mass screening for this disease. Positive and uncertain imaging findings should be followed up with high-field-strength MR imaging." />
<meta name="DC.Contributor" content="Frédérique Dubrulle" />
<meta name="DC.Contributor" content="Julia Delomez" />
<meta name="DC.Contributor" content="Alireza Kiaei" />
<meta name="DC.Contributor" content="Pierre Berger" />
<meta name="DC.Contributor" content="Christophe Vincent" />
<meta name="DC.Contributor" content="François-Michel M. Vaneecloo" />
<meta name="DC.Contributor" content="Laurent Lemaitre" />
<meta name="article:published_time" content="2002-06-01" />
<meta name="article:section" content="HEAD AND NECK" />
<meta name="citation_title" content="Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;i&gt;BACKGROUND AND PURPOSE:&lt;/i&gt; In patients with clinical symptoms suggestive of a retrocochlear disorder, contrast-enhanced T1-weighted spin-echo (SE) high-field-strength MR imaging is considered the criterion standard in assessing vestibular schwannoma. However, only 10–20% of its findings are pathologic. Our purpose was to prospectively compare the performance of low-field-strength MR imaging in screening for retrocochlear disorders, with high-field-strength MR imaging as the criterion standard.&lt;/p&gt;&lt;p&gt;&lt;i&gt;METHODS:&lt;/i&gt; A total of 287 patients with suspected retrocochlear disease underwent axial 1.5-T MR imaging with a T1-weighted SE sequence before and after contrast enhancement and with a high-resolution T2-weighted construction interference in steady state sequence. At immediate follow-up, the same patients underwent axial 0.2-T T1-weighted SE imaging without additional contrast enhancement. Results were classified as negative, positive, or uncertain and were analyzed in light of the patients’ clinical symptoms.&lt;/p&gt;&lt;p&gt;&lt;i&gt;RESULTS:&lt;/i&gt; MR imaging at 1.5 T depicted 63 disorders (21.95%), including 53 schwannomas, three other tumors, and seven other disorders (ie, gadolinium-enhancing inner ear, facial nerve, or meninges). MR imaging at 0.2 T showed evidence of 58 disorders; five disorders were not detected, although all schwannomas and other tumors were seen, including those smaller than 2 mm, and only two (28.6%) of the other disorders were detected. When correlated with clinical data, results showed that the five undetected disorders occurred in patients with unusual clinical signs.&lt;/p&gt;&lt;p&gt;&lt;i&gt;CONCLUSION:&lt;/i&gt; MR imaging at 0.2 T provided high sensitivity in detecting vestibular schwannoma of the internal auditory canal or cerebellopontine angle; it can be used for mass screening for this disease. Positive and uncertain imaging findings should be followed up with high-field-strength MR imaging.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="2002/06/01" />
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<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
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<meta name="citation_volume" content="23" />
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<meta name="citation_author" content="Frédérique Dubrulle" />
<meta name="citation_author_institution" content="Department of Radiology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France" />
<meta name="citation_author" content="Julia Delomez" />
<meta name="citation_author_institution" content="Department of Radiology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France" />
<meta name="citation_author" content="Alireza Kiaei" />
<meta name="citation_author_institution" content="Department of Neurology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France" />
<meta name="citation_author" content="Pierre Berger" />
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<meta name="citation_author" content="Christophe Vincent" />
<meta name="citation_author_institution" content="Department of Neurology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France" />
<meta name="citation_author" content="François-Michel M. Vaneecloo" />
<meta name="citation_author_institution" content="Department of Neurology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France" />
<meta name="citation_author" content="Laurent Lemaitre" />
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<meta name="twitter:title" content="Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging" />
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<meta name="twitter:image" content="http://ajnr-stage2.stage.highwire.org/sites/default/files/highwire/ajnr/23/6.cover.gif" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: In patients with clinical symptoms suggestive of a retrocochlear disorder, contrast-enhanced T1-weighted spin-echo (SE) high-field-strength MR imaging is considered the criterion standard in assessing vestibular schwannoma. However, only 10–20% of its findings are pathologic. Our purpose was to prospectively compare the performance of low-field-strength MR imaging in screening for retrocochlear disorders, with high-field-strength MR imaging as the criterion standard.

METHODS: A total of 287 patients with suspected retrocochlear disease underwent axial 1.5-T MR imaging with a T1-weighted SE sequence before and after contrast enhancement and with a high-resolution T2-weighted construction interference in steady state sequence. At immediate follow-up, the same patients underwent axial 0.2-T T1-weighted SE imaging without additional contrast enhancement. Results were classified as negative, positive, or uncertain and were analyzed in light of the patients’ clinical symptoms.

RESULTS: MR imaging at 1.5 T depicted 63 disorders (21.95%), including 53 schwannomas, three other tumors, and seven other disorders (ie, gadolinium-enhancing inner ear, facial nerve, or meninges). MR imaging at 0.2 T showed evidence of 58 disorders; five disorders were not detected, although all schwannomas and other tumors were seen, including those smaller than 2 mm, and only two (28.6%) of the other disorders were detected. When correlated with clinical data, results showed that the five undetected disorders occurred in patients with unusual clinical signs.

CONCLUSION: MR imaging at 0.2 T provided high sensitivity in detecting vestibular schwannoma of the internal auditory canal or cerebellopontine angle; it can be used for mass screening for this disease. Positive and uncertain imaging findings should be followed up with high-field-strength MR imaging." />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: In patients with clinical symptoms suggestive of a retrocochlear disorder, contrast-enhanced T1-weighted spin-echo (SE) high-field-strength MR imaging is considered the criterion standard in assessing vestibular schwannoma. However, only 10–20% of its findings are pathologic. Our purpose was to prospectively compare the performance of low-field-strength MR imaging in screening for retrocochlear disorders, with high-field-strength MR imaging as the criterion standard.

METHODS: A total of 287 patients with suspected retrocochlear disease underwent axial 1.5-T MR imaging with a T1-weighted SE sequence before and after contrast enhancement and with a high-resolution T2-weighted construction interference in steady state sequence. At immediate follow-up, the same patients underwent axial 0.2-T T1-weighted SE imaging without additional contrast enhancement. Results were classified as negative, positive, or uncertain and were analyzed in light of the patients’ clinical symptoms.

RESULTS: MR imaging at 1.5 T depicted 63 disorders (21.95%), including 53 schwannomas, three other tumors, and seven other disorders (ie, gadolinium-enhancing inner ear, facial nerve, or meninges). MR imaging at 0.2 T showed evidence of 58 disorders; five disorders were not detected, although all schwannomas and other tumors were seen, including those smaller than 2 mm, and only two (28.6%) of the other disorders were detected. When correlated with clinical data, results showed that the five undetected disorders occurred in patients with unusual clinical signs.

CONCLUSION: MR imaging at 0.2 T provided high sensitivity in detecting vestibular schwannoma of the internal auditory canal or cerebellopontine angle; it can be used for mass screening for this disease. Positive and uncertain imaging findings should be followed up with high-field-strength MR imaging." />
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    <title>Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging | American Journal of Neuroradiology</title>  
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      <h1 class="highwire-cite-title" id="page-title">Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Frédérique Dubrulle</span>, <span class="highwire-citation-author" data-delta="1">Julia Delomez</span>, <span class="highwire-citation-author" data-delta="2">Alireza Kiaei</span>, <span class="highwire-citation-author" data-delta="3">Pierre Berger</span>, <span class="highwire-citation-author" data-delta="4">Christophe Vincent</span>, <span class="highwire-citation-author" data-delta="5">François-Michel M. Vaneecloo</span> and <span class="highwire-citation-author" data-delta="6">Laurent Lemaitre</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">June 2002,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">23 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">918-923; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-10043--62037607435" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Frédérique Dubrulle </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Department of Radiology, Hopital Huriez, Centre Hospitalier Universitaire de Lille, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Fr%C3%A9d%C3%A9rique%2BDubrulle%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Dubrulle%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li 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      <div class="highwire-cite-title">Mass Screening for Retrocochlear Disorders: Low-Field-Strength (0.2-T) versus High-Field-Strength (1.5-T) MR Imaging</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Frédérique</span> <span class="nlm-surname">Dubrulle</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Julia</span> <span class="nlm-surname">Delomez</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Alireza</span> <span class="nlm-surname">Kiaei</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Pierre</span> <span class="nlm-surname">Berger</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Christophe</span> <span class="nlm-surname">Vincent</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">François-Michel M.</span> <span class="nlm-surname">Vaneecloo</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Laurent</span> <span class="nlm-surname">Lemaitre</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jun 2002, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">23 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">918-923; </span></div>
  
  
  
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