LetterLETTER
Standardized Calculation of Brain Parenchymal Fraction: An Approach to Objective Assessment of Cerebral Atrophy
Freimut D. Juengling and Jan Kassubek
American Journal of Neuroradiology August 2003, 24 (7) 1492-1493;
Freimut D. Juengling
aDepartment of Radiology, Neuroradiology and Nuclear Medicine, Inselspital and University Hospital of Bern, Bern, Switzerland
Jan Kassubek
bDepartment of Neurology, University of Ulm, Ulm, Germany

References
- ↵Ge Y, Grossman RI, Babb JS, et al. Age-related total gray matter and white matter changes in normal adult brain. Part I. Volumetric MR imaging analysis. AJNR Am J Neuroradiol 2002;23:1327–1333
- ↵Rudick RA, Fisher E, Lee JC, et al. Brain atrophy in relapsing multiple sclerosis: relationship to relapses, EDSS, and treatment with interferon beta-1a. Mult Scler 2000;6:365–372
- ↵Fisher E, Rudick RA, Cutter G, et al. Relationship between brain atrophy and disability: an 8-year follow-up study of multiple sclerosis patients. Mult Scler 2000;6:373–377
- ↵Chard DT, Parker GJ, Griffin CM, et al. The reproducibility and sensitivity of brain tissue volume measurements derived from an SPM-based segmentation methodology. J Magn Reson Imaging 2002;15:259–267
- ↵Chard DT, Griffin CM, Parker GJ, et al. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain 2002;125:327–337
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Standardized Calculation of Brain Parenchymal Fraction: An Approach to Objective Assessment of Cerebral Atrophy
Freimut D. Juengling, Jan Kassubek
American Journal of Neuroradiology Aug 2003, 24 (7) 1492-1493;
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