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    Frequency of Asymptomatic Microbleeds on T2*-Weighted MR Images of Patients with Recurrent Stroke: Association with Combination of Stroke Subtypes and Leukoaraiosis | American Journal of Neuroradiology  
    



















    





























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticleBRAIN

  
      

  
      
Frequency of Asymptomatic Microbleeds on T2*-Weighted MR Images of Patients with Recurrent Stroke: Association with Combination of Stroke Subtypes and Leukoaraiosis
  
    	
Hiromitsu Naka, Eiichi Nomura, Shinichi Wakabayashi, Hiroshi Kajikawa, Tatsuo Kohriyama, Yasuyo Mimori, Shigenobu Nakamura and Masayasu Matsumoto

  
    	
American Journal of Neuroradiology May 2004,  25 (5) 714-719; 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. ↵
    Tanaka A, Ueno Y, Nakayama Y, Takano K, Takebayashi S. Small chronic hemorrhages and ischemic lesions in association with spontaneous intracerebral hematomas. Stroke 1999;30:1637–1642
    Abstract/FREE Full Text
  2. ↵
    Fazekas F, Kleinert R, Roob G, et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds. AJNR Am J Neuroradiol 1999;20:637–642
    Abstract/FREE Full Text
  3. ↵
    Kwa VI, Franke CL, Verbeeten B Jr, Stam J. Silent intracerebral microhemorrhages in patients with ischemic stroke: Amsterdam Vascular Medicine Group. Ann Neurol 1998;44:372–377
    CrossRefPubMedWeb of Science
  4. Kinoshita T, Okudera T, Tamura H, Ogawa T, Hatazawa J. Assessment of lacunar hemorrhage associated with hypertensive stroke by echo-planar gradient-echo T2*-weighted MRI. Stroke 2000;31:1646–1650
    Abstract/FREE Full Text
  5. ↵
    Roob G, Lechner A, Schmidt R, Flooh E, Hartung HP, Fazekas F. Frequency and location of microbleeds in patients with primary intracerebral hemorrhage. Stroke 2000;31:2665–2669
    Abstract/FREE Full Text
  6. Tsushima Y, Tamura T, Unno Y, Kusano S, Endo K. Multifocal low-signal brain lesions on T2*-weighted gradient-echo imaging. Neuroradiology 2000;42:499–504
    CrossRefPubMedWeb of Science
  7. ↵
    Kato H, Izumiyama M, Izumiyama K, Takahashi A, Itoyama Y. Silent cerebral microbleeds on T2*-weighted MRI: correlation with stroke subtype, stroke recurrence, and leukoaraiosis. Stroke 2002;33:1536–1540
    Abstract/FREE Full Text
  8. ↵
    Kim DE, Bae HJ, Lee SH, Kim H, Yoon BW, Roh JK. Gradient echo magnetic resonance imaging in the prediction of hemorrhage vs ischemic stroke: a need for the consideration of the extent of leukoaraiosis. Arch Neurol 2002;59:425–429
    CrossRefPubMedWeb of Science
  9. ↵
    Tsushima Y, Aoki J, Endo K. Brain microhemorrhages detected on T2*-weighted gradient-echo MR images. AJNR Am J Neuroradiol 2003;24:88–96
    Abstract/FREE Full Text
  10. ↵
    Wong KS, Chan YL, Liu JY, Gao S, Lam WW. Asymptomatic microbleeds as a risk factor for aspirin-associated intracerebral hemorrhages. Neurology 2003;60:511–513
    Abstract/FREE Full Text
  11. ↵
    Gent M, Blakely JA, Easton JD, et al. The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Lancet 1989;1:1215–1220
    PubMedWeb of Science
  12. Hass WK, Easton JD, Adams HP Jr, et al. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients: Ticlopidine Aspirin Stroke Study Group. N Engl J Med 1989;321:501–507
    PubMedWeb of Science
  13. Antiplatelet Trialists’ Collaboration. Collaborative overview of randomized trials of antiplatelet therapy: I. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994;308:81–106
    Abstract/FREE Full Text
  14. CAPRIE Steering Committee. A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996;348:1329–1339
    CrossRefPubMedWeb of Science
  15. Hart RG, Sherman DG, Easton JD, Cairns JA. Prevention of stroke in patients with nonvalvular atrial fibrillation. Neurology 1998;51:674–681
    Abstract/FREE Full Text
  16. ↵
    Antithrombotic Trialists’ Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71–86
    Abstract/FREE Full Text
  17. ↵
    Special Report from the National Institute of Neurological Disorders and Stroke. Classification of Cerebrovascular Diseases III. Stroke 1990;21:637–676
    FREE Full Text
  18. ↵
    Lee SH, Bae HJ, Yoon BW, Kim H, Kim DE, Roh JK. Low concentration of serum total cholesterol is associated with multifocal signal loss lesions on gradient-echo magnetic resonance imaging: analysis of risk factors for multifocal signal loss lesions. Stroke 2002;33:2845–2849
    Abstract/FREE Full Text
  19. ↵
    Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5 T in Alzheimer’s dementia and normal aging. AJR Am J Roentgenol 1987;149:351–356
    CrossRefPubMedWeb of Science
  20. ↵
    Greenberg SM, Finklestein SP, Schaefer PW. Petechial hemorrhages accompanying lobar hemorrhage: detection by gradient-echo MRI. Neurology 1996;46:1751–1754
    Abstract/FREE Full Text
  21. ↵
    Greenberg SM, O’Donnell HC, Schaefer PW, Kraft E. MRI detection of new hemorrhages: potential marker of progression in cerebral amyloid angiopathy. Neurology 1999;53:1135–1138
    Abstract/FREE Full Text
  22. ↵
    Hermier M, Nighoghossian N, Derex L, et al. MRI of acute post-ischemic cerebral hemorrhage in stroke patients: diagnosis with T2*-weighted gradient-echo sequences. Neuroradiology 2001;43:809–815
    CrossRefPubMed
  23. ↵
    Kidwell CS, Saver JL, Villablanca JP, et al. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke 2002;33:95–98
    Abstract/FREE Full Text
  24. ↵
    Nighoghossian N, Hermier M, Adeleine P, et al. Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke: a gradient-echo T2*-weighted brain MRI study. Stroke 2002;33:735–742
    Abstract/FREE Full Text
  25. ↵
    Selekler K, Erzen C. Leukoaraiosis and intracerebral hematoma. Stroke 1989;20:1016–1020
    Abstract/FREE Full Text
  26. Inzitari D, Giordano GP, Ancona AL, Pracucci G, Mascalchi M, Amaducci L. Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension. Stroke 1990;21:1419–1423
    Abstract/FREE Full Text
  27. ↵
    Pantoni L, Garcia JH. Pathogenesis of leukoaraiosis: a review. Stroke 1997;28:652–659
    Abstract/FREE Full Text
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Frequency of Asymptomatic Microbleeds on T2*-Weighted MR Images of Patients with Recurrent Stroke: Association with Combination of Stroke Subtypes and Leukoaraiosis
  
    	
Hiromitsu Naka, Eiichi Nomura, Shinichi Wakabayashi, Hiroshi Kajikawa, Tatsuo Kohriyama, Yasuyo Mimori, Shigenobu Nakamura, Masayasu Matsumoto

  
    	
American Journal of Neuroradiology May 2004, 25 (5) 714-719; 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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