1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => FreeToRead
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)


  
    













































































































    Detection of Corticospinal Tract Compromise in Amyotrophic Lateral Sclerosis with Brain MR Imaging: Relevance of the T1-Weighted Spin-Echo Magnetization Transfer Contrast Sequence | American Journal of Neuroradiology  
    



















    





























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



    

  


  


  


  
  
  
  
  
  

  	      


    
      

    
  
    
        
    

  

    
                        

  

                
    

      

	  

		
		

			

			  

  
      
  
  

    

  
  
      
Research ArticleBRAIN

  
      

  
      
Detection of Corticospinal Tract Compromise in Amyotrophic Lateral Sclerosis with Brain MR Imaging: Relevance of the T1-Weighted Spin-Echo Magnetization Transfer Contrast Sequence
  
    	
Antônio J. da Rocha, Acary S.B. Oliveira, Ricardo B. Fonseca, Antônio C. M. Maia, Renata P. Buainain and Henrique M. Lederman

  
    	
American Journal of Neuroradiology October 2004,  25 (9) 1509-1515; 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. ↵
    Brownwell B, Oppenheimer DR, Hughes JT. The central nervous system in motor neuron disease. J Neurol Neurosurg Psychiatry 1970;33:338–357
    Abstract/FREE Full Text
  2. ↵
    Davidson CD. Amyotrophic lateral sclerosis: origin and extent of the upper motor neuron lesion. Arch Neurol 1941;46:1039–1056
  3. ↵
    Havercamp LJ, Appel V, Appel SH. Natural history of amyotrophic lateral sclerosis in a database population: validation of a scoring system and a model for survival prediction. Brain 1995;118:707–719
    Abstract/FREE Full Text
  4. ↵
    Goodin DS, Rowley HA, Olney RK. Magnetic resonance imaging in amyotrophic lateral sclerosis. Ann Neurol 1988;23:418–420
    CrossRefPubMedWeb of Science
  5. ↵
    Martí-Fabregas J, Pujol J. Selective involvement of the pyramidal tract on magnetic resonance imaging in primary lateral sclerosis. Neurology 1990;40:1799–1800
    FREE Full Text
  6. ↵
    Rowland LP. Diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 1998;160:S6–S24
  7. Brooks BR. Diagnostic dilemmas in amyotrophic lateral sclerosis. J Neurol Sci 1999;165:S1–S9
  8. ↵
    Rowland LP, Shneider NA. Amyotrophic lateral sclerosis. N Engl J Med 2001;344:1688–1700
    CrossRefPubMedWeb of Science
  9. ↵
    Hecht MJ, Fellner F, Fellner C, Hilz MJ, Heuss D, Neundörfer B. MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images. J Neurol Sci 2001;186:37–44
    CrossRefPubMedWeb of Science
  10. ↵
    da Rocha AJ, Maia Junior ACM, Nogueira RG, Lederman HM. Magnetic findings in amyotrophic lateral sclerosis using a spin echo magnetization transfer sequence. Preliminary report. Arq Neuropsiquiatr 1999;57:912–915
    PubMed
  11. ↵
    Brooks BR, Miller RG, Swash M, Munsat TL. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293–299
    CrossRefPubMedWeb of Science
  12. ↵
    Gelinas D. Effects of the early diagnosis of amyotrophic lateral sclerosis on the patient: advantages [Suppl]. Amyotroph Lateral Scler Other Motor Neuron Disord 2001;1:S73–S74
  13. ↵
    Dib Michel. Amyotrophic lateral sclerosis: progress and prospects for treatment. Drugs 2003;63:289–310
    CrossRefPubMedWeb of Science
  14. ↵
    Guermazi A. Is the high signal intensity in the corticospinal tract a sign of degeneration? AJNR Am J Neuroradiol 1996;17:801–802
    PubMed
  15. ↵
    Comi G, Rovaris M, Leocani L. Neuroimaging in amyotrophic lateral sclerosis. Eur J Neurol 1999;6:629–637
    CrossRefPubMed
  16. ↵
    Naidich TP, Blum JT, Firestone MI. The parasagittal line: an anatomical landmark for axial imaging. AJNR Am J Neuroradiol 2001;22:885–895
    Abstract/FREE Full Text
  17. ↵
    Karaarslan E, Arslan A. Perirolandic cortex of the normal brain: low signal intensity on turbo FLAIR MR images. Radiology 2003;227:538–541
    CrossRefPubMedWeb of Science
  18. ↵
    Oba H, Araki T, Ohtomo K, et al. Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology 1993;189:843–846
    PubMedWeb of Science
  19. ↵
    Zhang L, Ulug AM, Zimmerman RD, Lin MT, Rubin M, Beal MF. The diagnostic utility of FLAIR imaging in clinically verified amyotrophic lateral sclerosis. J Magn Reson Imaging 2003;17:521–527
    CrossRefPubMed
  20. ↵
    Hecht MJ, Fellner F, Fellner C, Hilz MJ, Neundorfer B, Heuss D. Hyperintense and hypointense MRI signals of the precentral gyrus and corticospinal tract in ALS: a follow-up examination including FLAIR images. J Neurol Sci 2002;199:59–65
    CrossRefPubMed
  21. ↵
    Iwasaki Y, Ikeda K, Shiojima T, Tagaya M, Kurihara T, Kinoshita M. Clinical significance of hypointensity in the motor cortex on T2-weighted images. Neurology 1994;44:1181
  22. ↵
    Imon Y, Yamagushi S, Katayama S, et al. A decrease in cerebral cortex intensity on T2-weighted with ageing images of normal subjects. Neuroradiology 1998;40:76–80
    CrossRefPubMedWeb of Science
  23. ↵
    Bowen BC, Pattany PM, Bradley WG, et al. MR imaging and localized proton spectroscopy of the precentral gyrus in amyotrophic lateral sclerosis. AJNR Am J Neuroradiol 2000;21:647–658
    Abstract/FREE Full Text
  24. ↵
    Thorpe JW, Moseley IF, Hawkes CH, MacManus DG, McDonald WI, Miller DH. Brain and spinal cord MRI in motor neuron disease. J Neurol Neurosurg Psychiatry 1996;61:314–317
    Abstract/FREE Full Text
  25. ↵
    Cheung G, Gawal MJ, Cooper PW, Farb RI, Ang LC. Amyotrophic lateral sclerosis: correlation of clinical and MR imaging findings. Radiology 1995;194:263–270
    PubMedWeb of Science
  26. ↵
    Peretti-Viton P, Azulay JP, Trefouret S, et al. MRI of the intracranial corticospinal tracts in amyotrophic and primary lateral sclerosis. Neuroradiology 1999;41:744–749
    CrossRefPubMedWeb of Science
  27. ↵
    Mirowitz S, Sartor K, Gado M, Torack R. Focal signal-intensity variations in the posterior limb of the internal capsule: normal MR findings and distinction from pathologic findings. Radiology 1989;172:535–539
    PubMed
  28. ↵
    Hajnal JV, Brjant DJ, Kasuboski L, et al. Use of fluid attenuated inversion recovery (FLAIR) pulse sequences in MRI of the brain. J Comput Assist Tomogr 1992;16:841–844
    PubMedWeb of Science
  29. ↵
    Gawne-Cain ML, Silver NC, Moseley IF, Miller DH. Fast FLAIR of the brain: the range of appearances in normal subjects and its application to quantification of white-matter disease. Neuroradiology 1997;39:243–249
    CrossRefPubMedWeb of Science
  30. ↵
    de Souza NM, Hajnal JV, Baudouin CJ. Potential for increasing conspicuity of short-T1 lesions in the brain using magnetization transfer imaging. Neuroradiology 1995;37:278–283
    PubMed
  31. ↵
    Loevner LA, Grossman RI, Cohen JA, Lexa JL, Kessler D, Kobson DL. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization transfer measurements. Radiology 1995;196:511–515
    PubMedWeb of Science
  32. ↵
    Kato Y, Matsumura K, Kinosoda Y, Narita Y, Kusuhara S, Nakagawa T. Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements. Am J Neurol 1997;18:1541–1547
  33. ↵
    Tanabe JL, Wermathen M, Miller R, Gelinas D, Weiner MW, Rooney WD. Reduced MTR in the corticospinal tract and normal T2 in amyotrophic lateral sclerosis. Magn Reson Imaging 1998;16:1163–1168
    CrossRefPubMedWeb of Science
  34. ↵
    Mehta RC, Pike GB, Enzmann DR. Measure of magnetization transfer in multiple sclerosis demyelinating plaques, white matter ischemic lesions, and edema. AJNR Am J Neuroradiol 1996;17:1051–1055
    Abstract
  35. Dousset V, Grossmann RI, Ramer KN, et al. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology 1992;182:483–491
    PubMedWeb of Science
  36. ↵
    Tomiak MM, Rosenblum JD, Prager JM, Metz CE. Magnetization transfer: a potential method to determine the age of multiple sclerosis lesions. AJNR Am J Neuroradiol 1994;15:1569–1574
    Abstract/FREE Full Text
  37. ↵
    Iwanaga K, Hayashi S, Oyake M, et al. Neuropathology of sporadic amyotrophic lateral sclerosis of long duration. J Neurol Sci 1997;146:139–143
    CrossRefPubMedWeb of Science
  38. ↵
    Waragai M. MRI and clinical features in amyotrophic lateral sclerosis. Neuroradiology 1997;39:847–851
    CrossRefPubMedWeb of Science
  39. ↵
    Okamoto K, Hirai S, Shoji M, Senoh Y, Yamazaki T. Axonal swelling in the corticospinal tract in amyotrophic lateral sclerosis. Acta Neuropathol 1990;80:222–226
    CrossRefPubMed
  40. ↵
    Belsh JM. Diagnostic challenges in ALS [Suppl]. Neurology 1999;53:S26–S30; discussion S35–S36
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

     Back to top  


  
  



			

		

		
		

			

			  

  
        
In this issue

    
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



  


  
  



  
      
  
  

    

	  
  

		

          

            

  
      
  
  

     Print  


  
  



  
      
  
  

     Download PDF  


  
  



  
      
  
  

    
 Email Article
  


  
  



  
      
  
  

    
 Citation Tools
  


  
  



          

        

        
        

          

            



  
      
  
  

    

  

    

  
      
  
  

    

  
  
  
  
      
Detection of Corticospinal Tract Compromise in Amyotrophic Lateral Sclerosis with Brain MR Imaging: Relevance of the T1-Weighted Spin-Echo Magnetization Transfer Contrast Sequence
  
    	
Antônio J. da Rocha, Acary S.B. Oliveira, Ricardo B. Fonseca, Antônio C. M. Maia, Renata P. Buainain, Henrique M. Lederman

  
    	
American Journal of Neuroradiology Oct 2004, 25 (9) 1509-1515; 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  


  
  



  



  


  
  



  
      
  
  

    
  


  
  



          

        

	
 	
	
	


  


  
  



  
        
Jump to section

    
  
  

    
  


  
  



  
      
  
  

    
  


  
  



			

		

	
	
 	
	
	


    

  



  

                
    

      

  

    

  
      
  
  

    


Advertisement