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<meta name="DC.Title" content="Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy" />
<meta name="DC.Date" content="2006-08-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant spinocerebellar ataxia. Techniques for the quantitative assessment of neurodegenerative lesions remain to be established in this disease. We attempted to quantify global and region-specific neurodegeneration in DRPLA using analysis of apparent diffusion coefficient (ADC) maps.

METHODS: Diffusion-weighted images (b = 1000 s/mm2) by echo-planar sequences were obtained with the use of a 1.5T clinical scanner. Whole-brain histogram and region of interest (ROI) analyses of ADC values as well as conventional MR imaging studies were performed in 6 patients with genetically confirmed DRPLA.

RESULTS: Histograms demonstrated significantly higher mean ADC values in the patients than in age- and sex-matched control subjects ( P &lt; .01). ROI analysis revealed that the patients had significantly higher ADC values in the cerebellum and globus pallidus, preferentially affected regions ( P &lt; .05), but not in the thalamus, the region relatively spared in this disease. ADC values in the white matter were higher only in patients with adult-onset disease. Histogram analyses could more sensitively identify abnormalities than ROI analyses, because the former avoided errors associated with setting ROIs and thus had smaller P values on statistical analysis than the latter.

CONCLUSIONS: Histogram ADC analyses were more sensitive for the detection of neurodegeneration in DRPLA than ROI analyses, whereas ROI analyses revealed regional alterations reflecting the distribution of pathologic changes. Thus, histogram and ROI analyses complement each other and may permit the sensitive, quantitative evaluation of neurodegeneration in DRPLA, especially that involving the globus pallidus showing normal T2 signals." />
<meta name="DC.Contributor" content="T. Kin" />
<meta name="DC.Contributor" content="M. Hirano" />
<meta name="DC.Contributor" content="T. Taoka" />
<meta name="DC.Contributor" content="Y. Furiya" />
<meta name="DC.Contributor" content="H. Kataoka" />
<meta name="DC.Contributor" content="K. Kichikawa" />
<meta name="DC.Contributor" content="S. Ueno" />
<meta name="article:published_time" content="2006-08-01" />
<meta name="article:section" content="BRAIN" />
<meta name="citation_title" content="Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;b&gt;BACKGROUND AND PURPOSE:&lt;/b&gt; Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant spinocerebellar ataxia. Techniques for the quantitative assessment of neurodegenerative lesions remain to be established in this disease. We attempted to quantify global and region-specific neurodegeneration in DRPLA using analysis of apparent diffusion coefficient (ADC) maps.&lt;/p&gt;&lt;p&gt;&lt;b&gt;METHODS:&lt;/b&gt; Diffusion-weighted images (b = 1000 s/mm&lt;sup&gt;2&lt;/sup&gt;) by echo-planar sequences were obtained with the use of a 1.5T clinical scanner. Whole-brain histogram and region of interest (ROI) analyses of ADC values as well as conventional MR imaging studies were performed in 6 patients with genetically confirmed DRPLA.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS:&lt;/b&gt; Histograms demonstrated significantly higher mean ADC values in the patients than in age- and sex-matched control subjects (&lt;i&gt;P&lt;/i&gt; &amp;lt; .01). ROI analysis revealed that the patients had significantly higher ADC values in the cerebellum and globus pallidus, preferentially affected regions (&lt;i&gt;P&lt;/i&gt; &amp;lt; .05), but not in the thalamus, the region relatively spared in this disease. ADC values in the white matter were higher only in patients with adult-onset disease. Histogram analyses could more sensitively identify abnormalities than ROI analyses, because the former avoided errors associated with setting ROIs and thus had smaller &lt;i&gt;P&lt;/i&gt; values on statistical analysis than the latter.&lt;/p&gt;&lt;p&gt;&lt;b&gt;CONCLUSIONS:&lt;/b&gt; Histogram ADC analyses were more sensitive for the detection of neurodegeneration in DRPLA than ROI analyses, whereas ROI analyses revealed regional alterations reflecting the distribution of pathologic changes. Thus, histogram and ROI analyses complement each other and may permit the sensitive, quantitative evaluation of neurodegeneration in DRPLA, especially that involving the globus pallidus showing normal T2 signals.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="T. Kin" />
<meta name="citation_author" content="M. Hirano" />
<meta name="citation_author" content="T. Taoka" />
<meta name="citation_author" content="Y. Furiya" />
<meta name="citation_author" content="H. Kataoka" />
<meta name="citation_author" content="K. Kichikawa" />
<meta name="citation_author" content="S. Ueno" />
<meta name="twitter:title" content="Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy" />
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METHODS: Diffusion-weighted images (b = 1000 s/mm2) by echo-planar sequences were obtained with the use of a 1.5T clinical scanner. Whole-brain histogram and region of interest (ROI) analyses of ADC values as well as conventional MR imaging studies were performed in 6 patients with genetically confirmed DRPLA.

RESULTS: Histograms demonstrated significantly higher mean ADC values in the patients than in age- and sex-matched control subjects ( P &lt; .01). ROI analysis revealed that the patients had significantly higher ADC values in the cerebellum and globus pallidus, preferentially affected regions ( P &lt; .05), but not in the thalamus, the region relatively spared in this disease. ADC values in the white matter were higher only in patients with adult-onset disease. Histogram analyses could more sensitively identify abnormalities than ROI analyses, because the former avoided errors associated with setting ROIs and thus had smaller P values on statistical analysis than the latter.

CONCLUSIONS: Histogram ADC analyses were more sensitive for the detection of neurodegeneration in DRPLA than ROI analyses, whereas ROI analyses revealed regional alterations reflecting the distribution of pathologic changes. Thus, histogram and ROI analyses complement each other and may permit the sensitive, quantitative evaluation of neurodegeneration in DRPLA, especially that involving the globus pallidus showing normal T2 signals." />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant spinocerebellar ataxia. Techniques for the quantitative assessment of neurodegenerative lesions remain to be established in this disease. We attempted to quantify global and region-specific neurodegeneration in DRPLA using analysis of apparent diffusion coefficient (ADC) maps.

METHODS: Diffusion-weighted images (b = 1000 s/mm2) by echo-planar sequences were obtained with the use of a 1.5T clinical scanner. Whole-brain histogram and region of interest (ROI) analyses of ADC values as well as conventional MR imaging studies were performed in 6 patients with genetically confirmed DRPLA.

RESULTS: Histograms demonstrated significantly higher mean ADC values in the patients than in age- and sex-matched control subjects ( P &lt; .01). ROI analysis revealed that the patients had significantly higher ADC values in the cerebellum and globus pallidus, preferentially affected regions ( P &lt; .05), but not in the thalamus, the region relatively spared in this disease. ADC values in the white matter were higher only in patients with adult-onset disease. Histogram analyses could more sensitively identify abnormalities than ROI analyses, because the former avoided errors associated with setting ROIs and thus had smaller P values on statistical analysis than the latter.

CONCLUSIONS: Histogram ADC analyses were more sensitive for the detection of neurodegeneration in DRPLA than ROI analyses, whereas ROI analyses revealed regional alterations reflecting the distribution of pathologic changes. Thus, histogram and ROI analyses complement each other and may permit the sensitive, quantitative evaluation of neurodegeneration in DRPLA, especially that involving the globus pallidus showing normal T2 signals." />
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      <h1 class="highwire-cite-title" id="page-title">Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">T. Kin</span>, <span class="highwire-citation-author" data-delta="1">M. Hirano</span>, <span class="highwire-citation-author" data-delta="2">T. Taoka</span>, <span class="highwire-citation-author" data-delta="3">Y. Furiya</span>, <span class="highwire-citation-author" data-delta="4">H. Kataoka</span>, <span class="highwire-citation-author" data-delta="5">K. Kichikawa</span> and <span class="highwire-citation-author" data-delta="6">S. Ueno</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">August 2006,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">27 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1463-1466; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-7181--6798653475" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">T. Kin </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=T.%2BKin%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Kin%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AT.%2BKin%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">M. Hirano </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BHirano%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Hirano%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM.%2BHirano%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">T. Taoka </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=T.%2BTaoka%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Taoka%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AT.%2BTaoka%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Y. Furiya </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.%2BFuriya%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Furiya%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AY.%2BFuriya%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">H. Kataoka </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=H.%2BKataoka%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Kataoka%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AH.%2BKataoka%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">K. Kichikawa </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=K.%2BKichikawa%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Kichikawa%20K&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AK.%2BKichikawa%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">S. 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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" xmlns:xhtml="http://www.w3.org/1999/xhtml" class="section ref-list" id="ref-list-1"><h2>References</h2><ol class="cit-list"><li><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1 in text" id="ref-1">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.1" data-doi="10.1038/ng0194-14"><div class="cit-metadata"><cite>Nagafuchi S, Yanagisawa H, Sato K, et al. <strong>Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p.</strong> <span class="cit-source">Nat Genet</span> <span class="cit-pub-date">1994</span>;<span class="cit-vol">6</span>:<span class="cit-fpage">14</span>–18</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1038/ng0194-14&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=8136826&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1994MQ17700007&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-2-1" title="View reference 2 in text" id="ref-2">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.2" data-doi="10.1038/ng0194-9"><div class="cit-metadata"><cite>Knoide R, Ikeuchi T, Onodera O, et al. <strong>Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA).</strong> <span class="cit-source">Nat Genet</span> <span class="cit-pub-date">1994</span>;<span class="cit-vol">6</span>:<span class="cit-fpage">9</span>–13</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1038/ng0194-9&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=8136840&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1994MQ17700006&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-3-1" title="View reference 3 in text" id="ref-3">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.3" data-doi="10.1007/s100480050046"><div class="cit-metadata"><cite>Kanazawa I. <strong>Dentatorubral-pallidoluysian atrophy or Naito-Oyanagi disease.</strong> <span class="cit-source">Neurogenetics</span> <span class="cit-pub-date">1998</span>;<span class="cit-vol">2</span>:<span class="cit-fpage">1</span>–17</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s100480050046&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=9933295&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000078353400001&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-4-1" title="View reference 4 in text" id="ref-4">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.4"><div class="cit-metadata"><cite>Naito H, Oyanagi S. <strong>Familial myoclonus epilepsy and choreoathetosis: hereditary dentatorubral-pallidoluysian atrophy.</strong> <span class="cit-source">Neurology</span> <span class="cit-pub-date">1982</span>;<span class="cit-vol">32</span>:<span class="cit-fpage">798</span>–807</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToibmV1cm9sb2d5IjtzOjU6InJlc2lkIjtzOjg6IjMyLzgvNzk4IjtzOjQ6ImF0b20iO3M6MjA6Ii9ham5yLzI3LzcvMTQ2My5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-5-1" title="View reference 5 in text" id="ref-5">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.5"><div class="cit-metadata"><cite>Miyazaki M, Hashimoto T, Yoneda Y, et al. <strong>Proton magnetic resonance spectroscopy on juvenile-onset dentatorubral-pallidoluysian atrophy (DRPLA).</strong> <span class="cit-source">Brain Dev</span> <span class="cit-pub-date">1996</span>;<span class="cit-vol">18</span>:<span class="cit-fpage">142</span>–46</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=8733908&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-6-1" title="View reference 6 in text" id="ref-6">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.6" data-doi="10.1006/jmrb.1996.0086"><div class="cit-metadata"><cite>Basser PJ, Pierpaoli C. <strong>Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI.</strong> <span class="cit-source">J Magn Res B</span> <span class="cit-pub-date">1996</span>;<span class="cit-vol">111</span>:<span class="cit-fpage">209</span>–19</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1006/jmrb.1996.0086&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-7-1" title="View reference 7 in text" id="ref-7">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.7"><div class="cit-metadata"><cite>Cercignani M, Bammer R, Sormani MP, et al. <strong>Inter-sequence and inter-imaging unit variabilia of diffusion tensor MR imaging histogram-derived metrics of the brain in healthy volunteers.</strong> <span class="cit-source">AJNR Am J Neuroradiol</span> <span class="cit-pub-date">2003</span>;<span class="cit-vol">24</span>:<span class="cit-fpage">638</span>–43</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyNC80LzYzOCI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-8-1" title="View reference 8 in text" id="ref-8">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.8" data-doi="10.1002/jmri.10050"><div class="cit-metadata"><cite>Mascalchi M, Tessa C, Moretti M, et al. <strong>Whole brain apparent diffusion coefficient histogram: a new tool for evaluation of leukoaraiosis.</strong> <span class="cit-source">J Magn Reson Imaging</span> <span class="cit-pub-date">2002</span>;<span class="cit-vol">15</span>:<span class="cit-fpage">144</span>–48</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1002/jmri.10050&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=11836769&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-9-1" title="View reference 9 in text" id="ref-9">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.9"><div class="cit-metadata"><cite>Chun T, Filippi CG, Zimmerman RD, et al. <strong>Diffusion changes in the aging human brain.</strong> <span class="cit-source">AJNR Am J Neuroradiol</span> <span class="cit-pub-date">2000</span>;<span class="cit-vol">21</span>:<span class="cit-fpage">1078</span>–83</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiIyMS82LzEwNzgiO3M6NDoiYXRvbSI7czoyMDoiL2FqbnIvMjcvNy8xNDYzLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-10-1" title="View reference 10 in text" id="ref-10">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.10"><div class="cit-metadata"><cite>Nusbaum AO, Tang CY, Buchsbaum MS, et al. <strong>Regional and global changes in cerebral diffusion with normal aging.</strong> <span class="cit-source">AJNR Am J Neuroradiol</span> <span class="cit-pub-date">2001</span>;<span class="cit-vol">22</span>:<span class="cit-fpage">136</span>–42</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyMi8xLzEzNiI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-11-1" title="View reference 11 in text" id="ref-11">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.11"><div class="cit-metadata"><cite>Bozzali M, Franceschi M, Falini A, et al. <strong>Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI.</strong> <span class="cit-source">Neurology</span> <span class="cit-pub-date">2001</span>;<span class="cit-vol">57</span>:<span class="cit-fpage">1135</span>–37</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToibmV1cm9sb2d5IjtzOjU6InJlc2lkIjtzOjk6IjU3LzYvMTEzNSI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-12-1" title="View reference 12 in text" id="ref-12">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.12"><div class="cit-metadata"><cite>Nusbaum AO, Tang CY, Wei T, et al. <strong>Whole-brain diffusion MR histograms differ between MS subtypes.</strong> <span class="cit-source">Neurology</span> <span class="cit-pub-date">2000</span>;<span class="cit-vol">54</span>:<span class="cit-fpage">1421</span>–27</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToibmV1cm9sb2d5IjtzOjU6InJlc2lkIjtzOjk6IjU0LzcvMTQyMSI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-13-1" title="View reference 13 in text" id="ref-13">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.13" data-doi="10.1002/1531-8249(200101)49:1&lt;14::AID-ANA5&gt;3.0.CO;2-X"><div class="cit-metadata"><cite>Yamada M, Wood JD, Shimohata T, et al. <strong>Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy.</strong> <span class="cit-source">Ann Neurol</span> <span class="cit-pub-date">2001</span>;<span class="cit-vol">49</span>:<span class="cit-fpage">14</span>–23</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1002/1531-8249(200101)49:1&lt;14::AID-ANA5&gt;3.0.CO;2-X&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=11198291&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000166968000003&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-14-1" title="View reference 14 in text" id="ref-14">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.14" data-doi="10.1002/ana.10352"><div class="cit-metadata"><cite>Yamada M, Sato T, Tsuji S, et al. <strong>Oligodendrocytic polyglutamine pathology in dentatorubral-pallidoluysian atrophy.</strong> <span class="cit-source">Ann Neurol</span> <span class="cit-pub-date">2002</span>;<span class="cit-vol">52</span>:<span class="cit-fpage">670</span>–74</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1002/ana.10352&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=12402270&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000178914000025&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-15-1" title="View reference 15 in text" id="ref-15">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.15" data-doi="10.1093/brain/122.9.1667"><div class="cit-metadata"><cite>Harris GJ, Codori AM, Lewis RF, et al. <strong>Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington’s disease.</strong> <span class="cit-source">Brain</span> <span class="cit-pub-date">1999</span>;<span class="cit-vol">122</span>:<span class="cit-fpage">1667</span>–78</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NToiYnJhaW4iO3M6NToicmVzaWQiO3M6MTA6IjEyMi85LzE2NjciO3M6NDoiYXRvbSI7czoyMDoiL2FqbnIvMjcvNy8xNDYzLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-16-1" title="View reference 16 in text" id="ref-16">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.16"><div class="cit-metadata"><cite>Munoz E, Mila M, Sanchez A, et al. <strong>Dentatorubropallidoluysian atrophy in a Spanish family: a clinical, radiological, pathological, and genetic study.</strong> <span class="cit-source">J Neurol Neurosurg Psychiatry</span> <span class="cit-pub-date">1999</span>;<span class="cit-vol">67</span>:<span class="cit-fpage">811</span>–14</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiam5ucCI7czo1OiJyZXNpZCI7czo4OiI2Ny82LzgxMSI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-17-1" title="View reference 17 in text" id="ref-17">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.17" data-doi="10.1016/0022-510X(95)00019-X"><div class="cit-metadata"><cite>Uyama E, Kondo I, Uchino M, et al. <strong>Dentatorubral-pallidoluysian atrophy (DRPLA): clinical, genetic, and neuroradiologic studies in a family.</strong> <span class="cit-source">J Neurol Sci</span> <span class="cit-pub-date">1995</span>;<span class="cit-vol">130</span>:<span class="cit-fpage">146</span>–53</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/0022-510X(95)00019-X&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=8586978&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1995RC74200005&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-18-1" title="View reference 18 in text" id="ref-18">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.18" data-doi="10.1074/jbc.M410210200"><div class="cit-metadata"><cite>Gardian G, Browne SE, Choi DK, et al. <strong>Neuroprotective effects of phenylbutyrate in the N171–82Q transgenic mouse model of Huntington’s disease.</strong> <span class="cit-source">J Biol Chem</span> <span class="cit-pub-date">2005</span>;<span class="cit-vol">280</span>:<span class="cit-fpage">556</span>–63</cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6MzoiamJjIjtzOjU6InJlc2lkIjtzOjk6IjI4MC8xLzU1NiI7czo0OiJhdG9tIjtzOjIwOiIvYWpuci8yNy83LzE0NjMuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><a class="rev-xref-ref" href="#xref-ref-19-1" title="View reference 19 in text" id="ref-19">↵</a><div class="cit ref-cit ref-other" id="cit-27.7.1463.19"><div class="cit-metadata"><cite>Kariya S, Hirano M, Uesato S, et al. <strong>Cytoprotective effect of novel histone deacetylase inhibitors against polyglutamine toxicity.</strong> <span class="cit-source">Neurosci Lett</span> <span class="cit-pub-date">2005</span>;<span class="cit-vol">392</span>:<span class="cit-fpage">213</span>–15</cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=16199124&amp;link_type=MED&amp;atom=%2Fajnr%2F27%2F7%2F1463.atom" class="cit-ref-sprinkles 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 27</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 7 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">August 2006 </div></div>
      
      
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      <div class="highwire-cite-title">Global and Region-Specific Analyses of Apparent Diffusion Coefficient in Dentatorubral-Pallidoluysian Atrophy</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">T.</span> <span class="nlm-surname">Kin</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Hirano</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">T.</span> <span class="nlm-surname">Taoka</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Furiya</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">H.</span> <span class="nlm-surname">Kataoka</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Kichikawa</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Ueno</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2006, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">27 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1463-1466; </span></div>
  
  
  
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