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    Serial Whole-Brain N-Acetylaspartate Concentration in Healthy Young Adults | American Journal of Neuroradiology  
    



















    































    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Serial Whole-Brain N-Acetylaspartate Concentration in Healthy Young Adults
  
    	
D.J. Rigotti, M. Inglese, J.S. Babb, M. Rovaris, B. Benedetti, M. Filippi, R.I. Grossman and O. Gonen

  
    	
American Journal of Neuroradiology October 2007,  28 (9) 1650-1651; DOI: https://doi.org/10.3174/ajnr.A0712 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. ↵
    Ross BD, Bluml S. Magnetic resonance spectroscopy of the human brain. Anat Rec 2001;265:54–84
    CrossRefPubMed
  2. ↵
    Birken DL, Oldendorf WH. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev 1989;13:23–31
    CrossRefPubMedWeb of Science
  3. ↵
    Simmons ML, Frondoza CG, Coyle JT. Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies. Neuroscience 1991;45:37–45
    CrossRefPubMedWeb of Science
  4. ↵
    Moffett JR, Namboodiri MA, Cangro CB, et al. Immunohistochemical localization of N-acetylaspartate in rat brain. Neuroreport 1991;2:131–34
    PubMedWeb of Science
  5. ↵
    Arnold DL, de Stefano N, Matthews PM, et al. N-acetylaspartate: usefulness as an indicator of viable neuronal tissue. Ann Neurol 2001;50:823; discussion 824–25
  6. ↵
    Miller DH, Grossman RI, Reingold SC, et al. The role of magnetic resonance techniques in understanding and managing multiple sclerosis. Brain 1998;121:3–24
    Abstract/FREE Full Text
  7. Sormani MP, Bruzzi P, Comi G, et al. MRI metrics as surrogate markers for clinical relapse rate in relapsing-remitting MS patients. Neurology 2002;58:417–21
    Abstract/FREE Full Text
  8. ↵
    Filippi M, Dousset V, McFarland HF, et al. Role of magnetic resonance imaging in the diagnosis and monitoring of multiple sclerosis: consensus report of the White Matter Study Group. J Magn Reson Imaging 2002;15:499–504
    CrossRefPubMedWeb of Science
  9. ↵
    Filippi M, Grossman RI. MRI techniques to monitor MS evolution: the present and the future. Neurology 2002;58:1147–53
    Abstract/FREE Full Text
  10. ↵
    Brooks WM, Friedman SD, Stidley CA. Reproducibility of 1H-MRS in vivo. Magn Reson Med 1999;41:193–97
    CrossRefPubMedWeb of Science
  11. ↵
    Inglese M, Ge Y, Filippi M, et al. Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis. Neuroimage 2004;21:1825–29
    CrossRefPubMedWeb of Science
  12. ↵
    De Santi S, de Leon MJ, Rusinek H, et al. Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging 2001;22:529–39
    CrossRefPubMedWeb of Science
  13. ↵
    Gonen O, Viswanathan AK, Catalaa I, et al. Total brain N-acetylaspartate concentration in normal, age-grouped females: quantitation with non-echo proton NMR spectroscopy. Magn Reson Med 1998;40:684–89
    PubMedWeb of Science
  14. ↵
    Scahill RI, Frost C, Jenkins R, et al. A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Arch Neurol 2003;60:989–94
    CrossRefPubMedWeb of Science
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Serial Whole-Brain N-Acetylaspartate Concentration in Healthy Young Adults
  
    	
D.J. Rigotti, M. Inglese, J.S. Babb, M. Rovaris, B. Benedetti, M. Filippi, R.I. Grossman, O. Gonen

  
    	
American Journal of Neuroradiology Oct 2007, 28 (9) 1650-1651; DOI: 10.3174/ajnr.A0712 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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