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    Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy | American Journal of Neuroradiology  
    



















    































    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticleHead and NeckF

  
      

  
      
Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy
  
    	
K. Šurlan-Popovič, S. Bisdas, Z. Rumboldt, T.S. Koh and P. Strojan

  
    	
American Journal of Neuroradiology March 2010,  31 (3) 570-575; DOI: https://doi.org/10.3174/ajnr.A1859 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. 1.↵


    1. Haddad  RI, 
    2. Shin  DM
    . Recent advances in head and neck cancer. N Engl J Med 2008;359:1143–54

    CrossRefPubMedWeb of Science
    

  2. 2.↵


    1. Pignon  JP, 
    2. Bourhis  J, 
    3. Domenge  C, 
    4. et al
    . Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949–55

    CrossRefPubMedWeb of Science
    

  3. 3.↵


    1. Bourhis  J, 
    2. Calais  G, 
    3. Lapeyre  M, 
    4. et al
    . Concomitant radiochemotherapy or accelerated radiotherapy: analysis of two randomized trials of the French Head and Neck Cancer Group (GORTEC). Semin Oncol 2004;31:822–26

    CrossRefPubMedWeb of Science
    

  4. 4.↵


    1. Hermans  R, 
    2. Lambin  P, 
    3. Van den Bogaert  W, 
    4. et al
    . Non-invasive tumour perfusion measurement by dynamic CT: preliminary results. Radiother Oncol 1997;44:159–62

    CrossRefPubMed
    

  5. 5.↵


    1. Bisdas  S, 
    2. Baghi  M, 
    3. Smolarz  A, 
    4. et al
    . Quantitative measurements of perfusion and permeability of oropharyngeal and oral cavity cancer, recurrent disease, and associated lymph nodes using first-pass contrast-enhanced computed tomography studies. Invest Radiol 2007;42:172–79

    CrossRefPubMed
    

  6. 6.↵


    1. Hermans  R, 
    2. Meijerink  M, 
    3. Van den Bogaert  W, 
    4. et al
    . Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy. Int J Radiat Oncol Biol Phys 2003;57:1351–56

    CrossRefPubMedWeb of Science
    

  7. 7.↵


    1. Hoskin  PJ, 
    2. Saunders  MI, 
    3. Goodchild  K, 
    4. et al
    . Dynamic contrast enhanced magnetic resonance scanning as a predictor of response to accelerated radiotherapy for advanced head and neck cancer. Br J Radiol 1999;72:1093–98

    Abstract
    

  8. 8.↵


    1. Gandhi  D, 
    2. Chepeha  DB, 
    3. Miller  T, 
    4. et al
    . Correlation between initial and early follow-up CT perfusion parameters with endoscopic tumor response in patients with advanced squamous cell carcinomas of the oropharynx treated with organ-preservation therapy. AJNR Am J Neuroradiol 2006;27:101–06

    Abstract/FREE Full Text
    

  9. 9.↵


    1. Zima  A, 
    2. Carlos  R, 
    3. Gandhi  D, 
    4. et al
    . Can pretreatment CT perfusion predict response of advanced squamous cell carcinoma of the upper aerodigestive tract treated with induction chemotherapy? AJNR Am J Neuroradiol 2007;28:328–34

    Abstract/FREE Full Text
    

  10. 10.↵


    1. Cao  Y, 
    2. Popovtzer  A, 
    3. Li  D, 
    4. et al
    . Early prediction of outcome in advanced head-and-neck cancer based on tumor blood volume alterations during therapy: a prospective study. Int J Radiat Oncol Biol Phys 2008;72:1287–90

    PubMed
    

  11. 11.↵


    1. Wiggenraad  R, 
    2. Mast  M, 
    3. van Santvoort  J, 
    4. et al
    . ConPas: a 3-D conformal parotid gland-sparing irradiation technique for bilateral neck treatment as an alternative to IMRT. Strahlenther Onkol 2005;181:673–82

    CrossRefPubMed
    

  12. 12.↵


    1. Bisdas  S, 
    2. Nguyen  SA, 
    3. Anand  SK, 
    4. et al
    . Outcome prediction after surgery and chemoradiation of squamous cell carcinoma in the oral cavity, oropharynx, and hypopharynx: use of baseline perfusion CT microcirculatory parameters vs. tumor volume. Int J Radiat Oncol Biol Phys 2009;73:1313–18

    PubMed
    

  13. 13.↵


    1. Billis  W, 
    2. Fuks  Z, 
    3. Kolesnick  R
    . Signaling in and regulation of ionizing radiation-induced apoptosis in endothelial cells. Recent Prog Horm Res 1998;53:85–92, discussion 93

    PubMed
    

  14. 14.↵


    1. Cemazar  M, 
    2. Parkins  CS, 
    3. Holder  AL, 
    4. et al
    . Electroporation of human microvascular endothelial cells: evidence for an anti-vascular mechanism of electrochemotherapy. Br J Cancer 2001;84:565–70

    CrossRefPubMed
    

  15. 15.↵


    1. Clements  MK, 
    2. Jones  CB, 
    3. Cumming  M, 
    4. et al
    . Antiangiogenic potential of camptothecin and topotecan. Cancer Chemother Pharmacol 1999;44:411–16

    CrossRefPubMedWeb of Science
    

  16. 16.↵


    1. Cooper  JS, 
    2. Fu  K, 
    3. Marks  J, 
    4. et al
    . Late effects of radiation therapy in the head and neck region. Int J Radiat Oncol Biol Phys 1995;31:1141–64

    CrossRefPubMedWeb of Science
    

  17. 17.↵


    1. Garcia-Barros  M, 
    2. Paris  F, 
    3. Cordon-Cardo  C, 
    4. et al
    . Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003;300:1155–59

    Abstract/FREE Full Text
    

  18. 18.↵


    1. Ng  QS, 
    2. Goh  V, 
    3. Milner  J, 
    4. et al
    . Acute tumor vascular effects following fractionated radiotherapy in human lung cancer: in vivo whole tumor assessment using volumetric perfusion computed tomography. Int J Radiat Oncol Biol Phys 2007;67:417–24

    PubMed
    

  19. 19.↵


    1. Ando  S, 
    2. Nojima  K, 
    3. Majima  H, 
    4. et al
    . Evidence for mRNA expression of vascular endothelial growth factor by x-ray irradiation in a lung squamous carcinoma cell line. Cancer Lett 1998;132:75–80

    CrossRefPubMed
    

  20. 20.↵


    1. Koutsimpelas  D, 
    2. Brieger  J, 
    3. Kim  DW, 
    4. et al
    . Proangiogenic effects of ionizing irradiation on squamous cell carcinoma of the hypopharynx. Auris Nasus Larynx 2008;35:369–75

    CrossRefPubMed
    

  21. 21.↵


    1. Gupta  VK, 
    2. Jaskowiak  NT, 
    3. Beckett  MA, 
    4. et al
    . Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J 2002;8:47–54

    CrossRefPubMedWeb of Science
    

  22. 22.↵


    1. Ash  L, 
    2. Teknos  TN, 
    3. Gandhi  D, 
    4. et al
    . Head and neck squamous cell carcinoma: CT perfusion can help noninvasively predict intratumoral microvessel density. Radiology 2009;251:422–28

    CrossRefPubMed
    

  23. 23.↵


    1. Kamijo  T, 
    2. Yokose  T, 
    3. Hasebe  T, 
    4. et al
    . Potential role of microvessel density in predicting radiosensitivity of T1 and T2 stage laryngeal squamous cell carcinoma treated with radiotherapy. Clin Cancer Res 2000;6:3159–65

    Abstract/FREE Full Text
    

  24. 24.↵


    1. Bisdas  S, 
    2. Surlan-Popovic  K, 
    3. Didanovic  V, 
    4. et al
    . Functional CT of squamous cell carcinoma in the head and neck: repeatability of tumor and muscle quantitative measurements, inter- and intra-observer agreement. Eur Radiol 2008;18:2241–50

    CrossRefPubMed
    

  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy
  
    	
K. Šurlan-Popovič, S. Bisdas, Z. Rumboldt, T.S. Koh, P. Strojan

  
    	
American Journal of Neuroradiology Mar 2010, 31 (3) 570-575; DOI: 10.3174/ajnr.A1859 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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