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    Perfusion CT in Squamous Cell Carcinoma of the Upper Aerodigestive Tract: Long-Term Predictive Value of Baseline Perfusion CT Measurements | American Journal of Neuroradiology  
    

















    





























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticleHead and NeckF

  
      

  
      
Perfusion CT in Squamous Cell Carcinoma of the Upper Aerodigestive Tract: Long-Term Predictive Value of Baseline Perfusion CT Measurements
  
    	
S. Bisdas, Z. Rumboldt, K. Šurlan-Popovič, M. Baghi, T.S. Koh, T.J. Vogl and M.G. Mack

  
    	
American Journal of Neuroradiology March 2010,  31 (3) 576-581; DOI: https://doi.org/10.3174/ajnr.A1852 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. 1.↵


    1. Pignon  JP, 
    2. Bourhis  J, 
    3. Domenge  C, 
    4. et al
    . Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data—MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949–55

    CrossRefPubMedWeb of Science
    

  2. 2.↵


    1. Bourhis  J, 
    2. Calais  G, 
    3. Lapeyre  M, 
    4. et al
    . Concomitant radiochemotherapy or accelerated radiotherapy: analysis of two randomized trials of the French Head and Neck Cancer Group (GORTEC). Semin Oncol 2004;31:822–26

    CrossRefPubMedWeb of Science
    

  3. 3.↵


    1. Garden  AS, 
    2. Harris  J, 
    3. Trotti  A, 
    4. et al
    . Long-term results of concomitant boost radiation plus concurrent cisplatin for advanced head and neck carcinomas: a phase II trial of the radiation therapy oncology group (RTOG 99–14). Int J Radiat Oncol Biol Phys 2008;71:1351–55

    PubMedWeb of Science
    

  4. 4.↵


    1. Bisdas  S, 
    2. Baghi  M, 
    3. Smolarz  A, 
    4. et al
    . Quantitative measurements of perfusion and permeability of oropharyngeal and oral cavity cancer, recurrent disease, and associated lymph nodes using first-pass contrast-enhanced computed tomography studies. Invest Radiol 2007;42:172–79

    CrossRefPubMed
    

  5. 5.↵


    1. Bisdas  S, 
    2. Medov  L, 
    3. Baghi  M, 
    4. et al
    . A comparison of tumour perfusion assessed by deconvolution-based analysis of dynamic contrast-enhanced CT and MR imaging in patients with squamous cell carcinoma of the upper aerodigestive tract. Eur Radiol 2008;18:843–50

    CrossRefPubMed
    

  6. 6.↵


    1. Gandhi  D, 
    2. Hoeffner  EG, 
    3. Carlos  RC, 
    4. et al
    . Computed tomography perfusion of squamous cell carcinoma of the upper aerodigestive tract: initial results. J Comput Assist Tomogr 2003;27:687–93

    CrossRefPubMed
    

  7. 7.↵


    1. Hermans  R, 
    2. Lambin  P, 
    3. Van den Bogaert  W, 
    4. et al
    . Non-invasive tumour perfusion measurement by dynamic CT: preliminary results. Radiother Oncol 1997;44:159–62

    CrossRefPubMed
    

  8. 8.↵


    1. Rumboldt  Z, 
    2. Al-Okaili  R, 
    3. Deveikis  JP
    . Perfusion CT for head and neck tumors: pilot study. AJNR Am J Neuroradiol 2005;26:1178–85

    Abstract/FREE Full Text
    

  9. 9.↵


    1. Gandhi  D, 
    2. Chepeha  DB, 
    3. Miller  T, 
    4. et al
    . Correlation between initial and early follow-up CT perfusion parameters with endoscopic tumor response in patients with advanced squamous cell carcinomas of the oropharynx treated with organ-preservation therapy. AJNR Am J Neuroradiol 2006;27:101–06

    Abstract/FREE Full Text
    

  10. 10.↵


    1. Zima  A, 
    2. Carlos  R, 
    3. Gandhi  D, 
    4. et al
    . Can pretreatment CT perfusion predict response of advanced squamous cell carcinoma of the upper aerodigestive tract treated with induction chemotherapy? AJNR Am J Neuroradiol 2007;28:328–34

    Abstract/FREE Full Text
    

  11. 11.↵


    1. Hermans  R, 
    2. Meijerink  M, 
    3. Van den Bogaert  W, 
    4. et al
    . Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy. Int J Radiat Oncol Biol Phys 2003;57:1351–56

    CrossRefPubMedWeb of Science
    

  12. 12.↵


    1. Hoskin  PJ, 
    2. Saunders  MI, 
    3. Goodchild  K, 
    4. et al
    . Dynamic contrast enhanced magnetic resonance scanning as a predictor of response to accelerated radiotherapy for advanced head and neck cancer. Br J Radiol 1999;72:1093–98

    Abstract
    

  13. 13.↵


    1. Bisdas  S, 
    2. Nguyen  SA, 
    3. Anand  SK, 
    4. et al
    . Outcome prediction after surgery and chemoradiation of squamous cell carcinoma in the oral cavity, oropharynx, and hypopharynx: use of baseline perfusion CT microcirculatory parameters vs. tumor volume. Int J Radiat Oncol Biol Phys 2009;73:1313–18. Epub 2008 Oct 27

    PubMed
    

  14. 14.↵


    1. Bisdas  S, 
    2. Surlan-Popovic  K, 
    3. Didanovic  V, 
    4. et al
    . Functional CT of squamous cell carcinoma in the head and neck: repeatability of tumor and muscle quantitative measurements—inter- and intra-observer agreement. Eur Radiol 2008;18:2241–50

    CrossRefPubMed
    

  15. 15.↵


    1. Cohen  EE, 
    2. Haraf  DJ, 
    3. List  MA, 
    4. et al
    . High survival and organ function rates after primary chemoradiotherapy for intermediate-stage squamous cell carcinoma of the head and neck treated in a multicenter phase II trial. J Clin Oncol 2006;24:3438–44

    Abstract/FREE Full Text
    

  16. 16.↵


    1. Calvin  DP, 
    2. Hammond  ME, 
    3. Pajak  TF, 
    4. et al
    . Microvessel density >or=60 does not predict for outcome after radiation treatment for locally advanced head and neck squamous cell carcinoma: results of a correlative study from the Radiation Therapy Oncology Group (RTOG) 90–03 Trial. Am J Clin Oncol 2007;30:406–19

    CrossRefPubMed
    

  17. 17.↵


    1. St Lawrence  KS, 
    2. Lee  TY
    . An adiabatic approximation to the tissue homogeneity model for water exchange in the brain. II. Experimental validation. J Cereb Blood Flow Metab 1998;18:1378–85

    CrossRefPubMed
    

  18. 18.↵


    1. St Lawrence  KS, 
    2. Lee  TY
    . An adiabatic approximation to the tissue homogeneity model for water exchange in the brain. I. Theoretical derivation. J Cereb Blood Flow Metab 1998;18:1365–77

    CrossRefPubMed
    

  19. 19.↵


    1. Bisdas  S, 
    2. Foo  CZ, 
    3. Thng  CH, 
    4. et al
    . Optimization of perfusion CT protocol for imaging of extracranial head and neck tumors. J Digit Imaging 2008 5 3. [Epub ahead of print]

    

  20. 20.↵


    1. Devries  AF, 
    2. Griebel  J, 
    3. Kremser  C, 
    4. et al
    . Tumor microcirculation evaluated by dynamic magnetic resonance imaging predicts therapy outcome for primary rectal carcinoma. Cancer Res 2001;61:2513–16

    Abstract/FREE Full Text
    

  21. 21.↵


    1. Xuan  JW, 
    2. Bygrave  M, 
    3. Jiang  H, 
    4. et al
    . Functional neoangiogenesis imaging of genetically engineered mouse prostate cancer using three-dimensional power Doppler ultrasound. Cancer Res 2007;67:2830–39

    Abstract/FREE Full Text
    

  22. 22.↵


    1. Axelson  H, 
    2. Fredlund  E, 
    3. Ovenberger  M, 
    4. et al
    . Hypoxia-induced dedifferentiation of tumor cells: a mechanism behind heterogeneity and aggressiveness of solid tumors. Semin Cell Dev Biol 2005;16:554–63

    CrossRefPubMedWeb of Science
    

  23. 23.↵


    1. Vaupel  P
    . Oxygen transport in tumors: characteristics and clinical implications. Adv Exp Med Biol 1996;388:341–51

    PubMed
    

  24. 24.↵


    1. Keski-Santti  H, 
    2. Atula  T, 
    3. Tikka  J, 
    4. et al
    . Predictive value of histopathologic parameters in early squamous cell carcinoma of oral tongue. Oral Oncol 2007;43:1007–13

    CrossRefPubMed
    

  25. 25.↵


    1. Hermans  R, 
    2. Op de beeck  K, 
    3. Van den Bogaert  W, 
    4. et al
    . The relation of CT-determined tumor parameters and local and regional outcome of tonsillar cancer after definitive radiation treatment. Int J Radiat Oncol Biol Phys 2001;50:37–45

    PubMed
    

  26. 26.↵


    1. Lam  W, 
    2. Bussom  S, 
    3. Cheng  YC
    . Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma. Mol Cancer Ther 2009;8:415–23. Epub 2009 Feb 10

    Abstract/FREE Full Text
    

  27. 27.↵


    1. Mayr  NA, 
    2. Wang  JZ, 
    3. Zhang  D, 
    4. et al
    . Synergistic effects of hemoglobin and tumor perfusion on tumor control and survival in cervical cancer. Int J Radiat Oncol Biol Phys 2009;74:1513–21. Epub 2009 Mar 13

    PubMed
    

  28. 28.↵


    1. Titz  B, 
    2. Jeraj  R
    . An imaging-based tumour growth and treatment response model: investigating the effect of tumour oxygenation on radiation therapy response. Phys Med Biol 2008;53:4471–88. Epub 2008 Aug 1

    CrossRefPubMedWeb of Science
    

  29. 29.↵


    1. Silva  P, 
    2. Slevin  NJ, 
    3. Sloan  P, 
    4. et al
    . Prognostic significance of tumor hypoxia inducible factor-1alpha expression for outcome after radiotherapy in oropharyngeal cancer. Int J Radiat Oncol Biol Phys 2008;72:1551–59

    PubMed
    

  30. 30.↵


    1. Jeremic  B, 
    2. Milicic  B
    . Pretreatment prognostic factors of survival in patients with locally advanced nonmetastatic squamous cell carcinoma of the head and neck treated with radiation therapy with or without concurrent chemotherapy. Am J Clin Oncol 2009 3 20. [Epub ahead of print]

    

  31. 31.↵


    1. Pedruzzi  PA, 
    2. Kowalski  LP, 
    3. Nishimoto  IN, 
    4. et al
    . Analysis of prognostic factors in patients with oropharyngeal squamous cell carcinoma treated with radiotherapy alone or in combination with systemic chemotherapy. Arch Otolaryngol Head Neck Surg 2008;134:1196–204

    CrossRefPubMed
    

  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Perfusion CT in Squamous Cell Carcinoma of the Upper Aerodigestive Tract: Long-Term Predictive Value of Baseline Perfusion CT Measurements
  
    	
S. Bisdas, Z. Rumboldt, K. Šurlan-Popovič, M. Baghi, T.S. Koh, T.J. Vogl, M.G. Mack

  
    	
American Journal of Neuroradiology Mar 2010, 31 (3) 576-581; DOI: 10.3174/ajnr.A1852 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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