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    Temozolomide (Temodar) | American Journal of Neuroradiology  
    

















    





























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticlePharmacology Vignette

  
      

  
      
Temozolomide (Temodar)
  
    	
J.R. Wesolowski, P. Rajdev and S.K. Mukherji

  
    	
American Journal of Neuroradiology September 2010,  31 (8) 1383-1384; DOI: https://doi.org/10.3174/ajnr.A2170 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. 1.↵


    1. Villano  JL, 
    2. Seery  TE, 
    3. Bressler  LR
    . Temozolomide in malignant gliomas: current use and future targets. Cancer Chemother Pharmacol 2009;64:647–55
    CrossRefPubMedWeb of Science
  2. 2.↵


    1. Kufe  DW, 
    2. Frei  E, 
    3. Holland  JF, 
    4. et al.
    1. Colvin  M
    . Alkylating agents and platinum antitumor compounds. In:

Kufe  DW, 
Frei  E, 
Holland  JF, et al. eds. Holland-Frei Cancer Medicine. 8th ed. Shelton, Connecticut: People's Medical Publishing House; 2010
  3. 3.↵


    1. Newlands  ES, 
    2. Stevens  MF, 
    3. Wedge  SR, 
    4. et al
    . Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev 1997;23:35–61
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  4. 4.↵


    1. Agarwala  SS, 
    2. Kirkwood  JM
    . Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma. Oncologist 2000;5:144–51
    Abstract/FREE Full Text
  5. 5.↵


    1. Friedman  HS, 
    2. Kerby  T, 
    3. Calvert  H
    . Temozolomide and treatment of malignant glioma. Clin Cancer Res 2000;6:2585–97
    Abstract/FREE Full Text
  6. 6.↵


    1. Nagasubramanian  R, 
    2. Dolan  ME
    . Temozolomide: realizing the promise and potential. Curr Opin Oncol 2003;15:412–18
    CrossRefPubMed
  7. 7.↵


    1. Quirt  I, 
    2. Verma  S, 
    3. Petrella  T, 
    4. et al
    . Temozolomide for the treatment of metastatic melanoma: a systematic review. Oncologist 2007;12:1114–23
    Abstract/FREE Full Text
  8. 8.↵


    1. McEvoy  GK, 
    2. Snow  EK, 
    3. Jane Miller  J, 
    4. et al.
     eds. AHFS Drug Information. Bethesda, Maryland: American Society of Health-System Pharmacists; 2009
  9. 9.↵


    1. Singhal  N, 
    2. Selva-Nayagam  S, 
    3. Brown  MP
    . Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment: case study and review of literature. J Neurooncol 2007;85:229–30
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    1. Klepper  B, 
    2. Pauker  D
    . Medicare's drug plan: huge price disparities for common cancer drugs. Community Oncology 2006;3:753–55
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    1. Crott  R
    . The economics of temozolomide in brain cancer. Expert Opin Pharmacother 2007;8:1923–29
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  12. 12.↵


    1. Pierson  R
    . Teva wins patent battle over Merck's Temodar. Reuters. January 26, 2010. Available at http://www.reuters.com/article/idUSN2611057820100126. Accessed May 31, 2010.
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Temozolomide (Temodar)
  
    	
J.R. Wesolowski, P. Rajdev, S.K. Mukherji

  
    	
American Journal of Neuroradiology Sep 2010, 31 (8) 1383-1384; DOI: 10.3174/ajnr.A2170 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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