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      <h1 class="highwire-cite-title" id="page-title">Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">C.-S. Tung</span>, <span class="highwire-citation-author" data-delta="1">S.-L. Wu</span>, <span class="highwire-citation-author" data-delta="2">J.-C. Tsou</span>, <span class="highwire-citation-author" data-delta="3">S.-P. Hsu</span>, <span class="highwire-citation-author" data-delta="4">H.-C. Kuo</span> and <span class="highwire-citation-author" data-delta="5">H.-W. Tsui</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 2010,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1506-1507; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A1897 </span></div>
  
  
  
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<p id="p-1"><strong>SUMMARY:</strong> MBD is a rare disorder strongly associated with alcoholism. It is characterized pathologically by demyelination and necrosis of the corpus callosum. MBD presents with severe neurologic deficits and significant sequelae developing in most survivors. We report a patient with total clinical recovery. Serial MR imaging demonstrated typical lesions with restricted diffusion in the acute stage and total resolution without atrophy or cystic change.</p>
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</div><div class="section glossary" id="glossary-1"><h2>Abbreviations</h2><dl id="def-list-1"><dt id="def-item-1">ADC<span class="def-item-dt-sep"></span></dt><dd>apparent diffusion coefficient<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">DWI<span class="def-item-dt-sep"></span></dt><dd>diffusion-weighted imaging<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">MBD<span class="def-item-dt-sep"></span></dt><dd>Marchiafava-Bignami disease<span class="def-item-dd-sep"></span></dd><dt id="def-item-4">T1WI<span class="def-item-dt-sep"></span></dt><dd>T1-weighted imaging<span class="def-item-dd-sep"></span></dd><dt id="def-item-5">T2WI<span class="def-item-dt-sep"></span></dt><dd>T2-weighted imaging</dd></dl></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">Copyright © American Society of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div><a href="http://ajnr-stage2.stage.highwire.org/content/31/8/1506.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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      <div class="highwire-cite-title">Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">C.-S.</span> <span class="nlm-surname">Tung</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S.-L.</span> <span class="nlm-surname">Wu</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">J.-C.</span> <span class="nlm-surname">Tsou</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">S.-P.</span> <span class="nlm-surname">Hsu</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">H.-C.</span> <span class="nlm-surname">Kuo</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">H.-W.</span> <span class="nlm-surname">Tsui</span></span></span></div>
  
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      <div class="highwire-cite-title">Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">C.-S.</span> <span class="nlm-surname">Tung</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S.-L.</span> <span class="nlm-surname">Wu</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">J.-C.</span> <span class="nlm-surname">Tsou</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">S.-P.</span> <span class="nlm-surname">Hsu</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">H.-C.</span> <span class="nlm-surname">Kuo</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">H.-W.</span> <span class="nlm-surname">Tsui</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 2010, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1506-1507; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A1897 </span></div>
  
  
  
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