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<meta name="DC.Title" content="Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features" />
<meta name="DC.Identifier" content="10.3174/ajnr.A2361" />
<meta name="DC.Date" content="2011-01-01" />
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<meta name="DC.Description" content="SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.

ADC
:   apparent diffusion coefficient
AT/RT
:   atypical teratoid/rhabdoid tumor
CNS
:   central nervous system
DWI
:   diffusion-weighted imaging
FLAIR
:   fluid-attenuated inversion recovery
L
:   left
mRNA
:   messenger ribonucleic acid
N/A
:   not available
ND
:   not depicted
OS
:   overall survival
PNET
:   primitive neuroectodermal tumor
PR
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R
:   right
TR
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<meta name="DC.Contributor" content="L. Han" />
<meta name="DC.Contributor" content="Y. Qiu" />
<meta name="DC.Contributor" content="C. Xie" />
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<meta name="DC.Contributor" content="W. Xiong" />
<meta name="DC.Contributor" content="W. Wang" />
<meta name="DC.Contributor" content="X. Zhang" />
<meta name="DC.Contributor" content="P. Wu" />
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&lt;p&gt;Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.&lt;/p&gt;" />
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<meta name="twitter:title" content="Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features" />
<meta name="twitter:card" content="summary_large_image" />
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<meta name="twitter:description" content="SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.

ADC
:   apparent diffusion coefficient
AT/RT
:   atypical teratoid/rhabdoid tumor
CNS
:   central nervous system
DWI
:   diffusion-weighted imaging
FLAIR
:   fluid-attenuated inversion recovery
L
:   left
mRNA
:   messenger ribonucleic acid
N/A
:   not available
ND
:   not depicted
OS
:   overall survival
PNET
:   primitive neuroectodermal tumor
PR
:   partial resection
R
:   right
TR
:   total resection" />
<meta name="og-title" property="og:title" content="Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features" />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.

ADC
:   apparent diffusion coefficient
AT/RT
:   atypical teratoid/rhabdoid tumor
CNS
:   central nervous system
DWI
:   diffusion-weighted imaging
FLAIR
:   fluid-attenuated inversion recovery
L
:   left
mRNA
:   messenger ribonucleic acid
N/A
:   not available
ND
:   not depicted
OS
:   overall survival
PNET
:   primitive neuroectodermal tumor
PR
:   partial resection
R
:   right
TR
:   total resection" />
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      <h1 class="highwire-cite-title" id="page-title">Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">L. Han</span>, <span class="highwire-citation-author" data-delta="1">Y. Qiu</span>, <span class="highwire-citation-author" data-delta="2">C. Xie</span>, <span class="highwire-citation-author" data-delta="3">J. Zhang</span>, <span class="highwire-citation-author" data-delta="4">X. Lv</span>, <span class="highwire-citation-author" data-delta="5">W. Xiong</span>, <span class="highwire-citation-author" data-delta="6">W. Wang</span>, <span class="highwire-citation-author" data-delta="7">X. Zhang</span> and <span class="highwire-citation-author" data-delta="8">P. Wu</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">January 2011,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">103-108; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A2361 </span></div>
  
  
  
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