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<meta name="DC.Title" content="Cough-Associated Headache in Patients with Chiari I Malformation: CSF Flow Analysis by Means of Cine Phase-Contrast MR Imaging" />
<meta name="DC.Identifier" content="10.3174/ajnr.A2369" />
<meta name="DC.Date" content="2011-04-01" />
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<meta name="DC.Description" content="SUMMARY: The purpose of this study was to analyze the CSF flow in patients with Chiari I to determine differences between patients with and without CAH. Thirty patients with Chiari I malformation underwent cine-PC CSF flow imaging in the sagittal plane. CSF flow pulsations were analyzed by placing regions of interest in the anterior cervical subarachnoid space. Maximum CSF systolic (craniocaudal) and diastolic (caudocranial) velocities as well as the durations of CSF systole and diastole (measured in fractions of the cardiac cycle) were determined. In the region of interest just below the foramen magnum, patients with CAH had a significantly shorter CSF systole and longer diastole ( P = .02). A CSF diastolic length of ≥0.75 of the cardiac cycle was 67% sensitive and 86% specific for CAH. Our results indicate that Cine-PC imaging can show differences in CSF flow patterns in patients with Chiari I with and without CAH.

CAH
:   cough-associated headache
Cine-PC
:   cine phase-contrast
CSF diastole
:   duration of CSF diastolic flow (fraction of the cardiac cycle)
CSF systole
:   duration of CSF systolic flow (fraction of the cardiac cycle)
MSV
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MDV
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<meta name="DC.Contributor" content="R.A. Bhadelia" />
<meta name="DC.Contributor" content="E. Frederick" />
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<meta name="DC.Contributor" content="P. Dubey" />
<meta name="DC.Contributor" content="S.H. Erbay" />
<meta name="DC.Contributor" content="D. Do-Dai" />
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<meta name="article:published_time" content="2011-04-01" />
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&lt;p&gt;The purpose of this study was to analyze the CSF flow in patients with Chiari I to determine differences between patients with and without CAH. Thirty patients with Chiari I malformation underwent cine-PC CSF flow imaging in the sagittal plane. CSF flow pulsations were analyzed by placing regions of interest in the anterior cervical subarachnoid space. Maximum CSF systolic (craniocaudal) and diastolic (caudocranial) velocities as well as the durations of CSF systole and diastole (measured in fractions of the cardiac cycle) were determined. In the region of interest just below the foramen magnum, patients with CAH had a significantly shorter CSF systole and longer diastole (&lt;i&gt;P&lt;/i&gt; = .02). A CSF diastolic length of ≥0.75 of the cardiac cycle was 67% sensitive and 86% specific for CAH. Our results indicate that Cine-PC imaging can show differences in CSF flow patterns in patients with Chiari I with and without CAH.&lt;/p&gt;" />
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<meta name="twitter:description" content="SUMMARY: The purpose of this study was to analyze the CSF flow in patients with Chiari I to determine differences between patients with and without CAH. Thirty patients with Chiari I malformation underwent cine-PC CSF flow imaging in the sagittal plane. CSF flow pulsations were analyzed by placing regions of interest in the anterior cervical subarachnoid space. Maximum CSF systolic (craniocaudal) and diastolic (caudocranial) velocities as well as the durations of CSF systole and diastole (measured in fractions of the cardiac cycle) were determined. In the region of interest just below the foramen magnum, patients with CAH had a significantly shorter CSF systole and longer diastole ( P = .02). A CSF diastolic length of ≥0.75 of the cardiac cycle was 67% sensitive and 86% specific for CAH. Our results indicate that Cine-PC imaging can show differences in CSF flow patterns in patients with Chiari I with and without CAH.

CAH
:   cough-associated headache
Cine-PC
:   cine phase-contrast
CSF diastole
:   duration of CSF diastolic flow (fraction of the cardiac cycle)
CSF systole
:   duration of CSF systolic flow (fraction of the cardiac cycle)
MSV
:   maximum systolic velocity (millimeters/second)
MDV
:   maximum diastolic velocity (millimeters/second)" />
<meta name="og-title" property="og:title" content="Cough-Associated Headache in Patients with Chiari I Malformation: CSF Flow Analysis by Means of Cine Phase-Contrast MR Imaging" />
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<meta name="og-description" property="og:description" content="SUMMARY: The purpose of this study was to analyze the CSF flow in patients with Chiari I to determine differences between patients with and without CAH. Thirty patients with Chiari I malformation underwent cine-PC CSF flow imaging in the sagittal plane. CSF flow pulsations were analyzed by placing regions of interest in the anterior cervical subarachnoid space. Maximum CSF systolic (craniocaudal) and diastolic (caudocranial) velocities as well as the durations of CSF systole and diastole (measured in fractions of the cardiac cycle) were determined. In the region of interest just below the foramen magnum, patients with CAH had a significantly shorter CSF systole and longer diastole ( P = .02). A CSF diastolic length of ≥0.75 of the cardiac cycle was 67% sensitive and 86% specific for CAH. Our results indicate that Cine-PC imaging can show differences in CSF flow patterns in patients with Chiari I with and without CAH.

CAH
:   cough-associated headache
Cine-PC
:   cine phase-contrast
CSF diastole
:   duration of CSF diastolic flow (fraction of the cardiac cycle)
CSF systole
:   duration of CSF systolic flow (fraction of the cardiac cycle)
MSV
:   maximum systolic velocity (millimeters/second)
MDV
:   maximum diastolic velocity (millimeters/second)" />
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      <h1 class="highwire-cite-title" id="page-title">Cough-Associated Headache in Patients with Chiari I Malformation: CSF Flow Analysis by Means of Cine Phase-Contrast MR Imaging</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">R.A. Bhadelia</span>, <span class="highwire-citation-author" data-delta="1">E. Frederick</span>, <span class="highwire-citation-author" data-delta="2">S. Patz</span>, <span class="highwire-citation-author" data-delta="3">P. Dubey</span>, <span class="highwire-citation-author" data-delta="4">S.H. Erbay</span>, <span class="highwire-citation-author" data-delta="5">D. Do-Dai</span> and <span class="highwire-citation-author" data-delta="6">C. Heilman</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">April 2011,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">739-742; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A2369 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-9463--61371333986" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">R.A. Bhadelia </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.A.%2BBhadelia%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bhadelia%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AR.A.%2BBhadelia%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">E. 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                  		Comparison of tonsillar herniation, CSF velocities, and flow durations in patients with Chiari I without and with CAH
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2011, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">739-742; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2369 </span></div>
  
  
  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2011, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">739-742; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2369 </span></div>
  
  
  
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