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<meta name="DC.Title" content="Restoration of Spinal Alignment and Disk Mechanics following Polyetheretherketone Wafer Kyphoplasty with StaXx FX" />
<meta name="DC.Identifier" content="10.3174/ajnr.A2484" />
<meta name="DC.Date" content="2011-08-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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www.ajnr.org" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: EPFs sustained during VCFs degrade the disk's ability to develop IDP under load. This inability to develop pressure in combination with residual kyphotic deformity increases the risk for adjacent vertebral fractures. We tested the hypothesis that StaXx FX reduces kyphosis and endplate deformity following vertebral compression fracture, restoring disk mechanics.

MATERIALS AND METHODS: Eight thoracolumbar, 5-vertebrae segments were tested. A void was selectively created in the middle vertebra. The specimens were compressed until EPF and to a grade I–II VCF. PEEK wafer kyphoplasty was then performed. The specimens were then tested in flexion-extension (±6 Nm) under 400-N preload intact, after EPF, VCF, and kyphoplasty. Endplate deformity, kyphosis, and IDP adjacent to the fractured body were measured.

RESULTS: Vertebral body height at the point of maximal endplate deformity decreased after EPF and VCF and was partially corrected after StaXx FX, remaining less than intact ( P = .047). Anterior vertebral height decreased after VCF ( P = .002) and was partially restored with StaXx FX, remaining less than intact ( P = .015). Vertebral kyphosis increased after VCF ( P &lt; .001) and reduced after StaXx FX, remaining greater than intact ( P = .03). EPF reduced IDP in the affected disk in compression-flexion loading ( P &lt; .001), which was restored after StaXx FX ( P = 1.0). IDP in the unaffected disk did not change during testing ( P &gt; .3).

CONCLUSIONS: StaXx FX reduced endplate deformity and kyphosis, and significantly increased anterior height following VCF. Although height and kyphosis were not fully corrected, the disk's ability to pressurize under load was restored.

EPF
:   endplate fracture
IDP
:   intradiskal pressure
PEEK
:   polyetherether-ketone
VCF
:   vertebral compression fracture" />
<meta name="DC.Contributor" content="S.M. Renner" />
<meta name="DC.Contributor" content="P.P. Tsitsopoulos" />
<meta name="DC.Contributor" content="A.T. Dimitriadis" />
<meta name="DC.Contributor" content="L.I. Voronov" />
<meta name="DC.Contributor" content="R.M. Havey" />
<meta name="DC.Contributor" content="G. Carandang" />
<meta name="DC.Contributor" content="B. McIntosh" />
<meta name="DC.Contributor" content="C. Carson" />
<meta name="DC.Contributor" content="D. Ty" />
<meta name="DC.Contributor" content="J.G. Ringelstein" />
<meta name="DC.Contributor" content="A.G. Patwardhan" />
<meta name="article:published_time" content="2011-08-01" />
<meta name="article:section" content="Spine" />
<meta name="citation_title" content="Restoration of Spinal Alignment and Disk Mechanics following Polyetheretherketone Wafer Kyphoplasty with StaXx FX" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;EPFs sustained during VCFs degrade the disk9s ability to develop IDP under load. This inability to develop pressure in combination with residual kyphotic deformity increases the risk for adjacent vertebral fractures. We tested the hypothesis that StaXx FX reduces kyphosis and endplate deformity following vertebral compression fracture, restoring disk mechanics.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Eight thoracolumbar, 5-vertebrae segments were tested. A void was selectively created in the middle vertebra. The specimens were compressed until EPF and to a grade I–II VCF. PEEK wafer kyphoplasty was then performed. The specimens were then tested in flexion-extension (±6 Nm) under 400-N preload intact, after EPF, VCF, and kyphoplasty. Endplate deformity, kyphosis, and IDP adjacent to the fractured body were measured.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Vertebral body height at the point of maximal endplate deformity decreased after EPF and VCF and was partially corrected after StaXx FX, remaining less than intact (&lt;i&gt;P&lt;/i&gt; = .047). Anterior vertebral height decreased after VCF (&lt;i&gt;P&lt;/i&gt; = .002) and was partially restored with StaXx FX, remaining less than intact (&lt;i&gt;P&lt;/i&gt; = .015). Vertebral kyphosis increased after VCF (&lt;i&gt;P&lt;/i&gt; &amp;lt; .001) and reduced after StaXx FX, remaining greater than intact (&lt;i&gt;P&lt;/i&gt; = .03). EPF reduced IDP in the affected disk in compression-flexion loading (&lt;i&gt;P&lt;/i&gt; &amp;lt; .001), which was restored after StaXx FX (&lt;i&gt;P&lt;/i&gt; = 1.0). IDP in the unaffected disk did not change during testing (&lt;i&gt;P&lt;/i&gt; &amp;gt; .3).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;StaXx FX reduced endplate deformity and kyphosis, and significantly increased anterior height following VCF. Although height and kyphosis were not fully corrected, the disk9s ability to pressurize under load was restored.&lt;/p&gt;" />
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<meta name="twitter:title" content="Restoration of Spinal Alignment and Disk Mechanics following Polyetheretherketone Wafer Kyphoplasty with StaXx FX" />
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<meta name="twitter:image" content="http://ajnr-stage2.stage.highwire.org/sites/default/files/highwire/ajnr/32/7.cover.gif" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: EPFs sustained during VCFs degrade the disk's ability to develop IDP under load. This inability to develop pressure in combination with residual kyphotic deformity increases the risk for adjacent vertebral fractures. We tested the hypothesis that StaXx FX reduces kyphosis and endplate deformity following vertebral compression fracture, restoring disk mechanics.

MATERIALS AND METHODS: Eight thoracolumbar, 5-vertebrae segments were tested. A void was selectively created in the middle vertebra. The specimens were compressed until EPF and to a grade I–II VCF. PEEK wafer kyphoplasty was then performed. The specimens were then tested in flexion-extension (±6 Nm) under 400-N preload intact, after EPF, VCF, and kyphoplasty. Endplate deformity, kyphosis, and IDP adjacent to the fractured body were measured.

RESULTS: Vertebral body height at the point of maximal endplate deformity decreased after EPF and VCF and was partially corrected after StaXx FX, remaining less than intact ( P = .047). Anterior vertebral height decreased after VCF ( P = .002) and was partially restored with StaXx FX, remaining less than intact ( P = .015). Vertebral kyphosis increased after VCF ( P &lt; .001) and reduced after StaXx FX, remaining greater than intact ( P = .03). EPF reduced IDP in the affected disk in compression-flexion loading ( P &lt; .001), which was restored after StaXx FX ( P = 1.0). IDP in the unaffected disk did not change during testing ( P &gt; .3).

CONCLUSIONS: StaXx FX reduced endplate deformity and kyphosis, and significantly increased anterior height following VCF. Although height and kyphosis were not fully corrected, the disk's ability to pressurize under load was restored.

EPF
:   endplate fracture
IDP
:   intradiskal pressure
PEEK
:   polyetherether-ketone
VCF
:   vertebral compression fracture" />
<meta name="og-title" property="og:title" content="Restoration of Spinal Alignment and Disk Mechanics following Polyetheretherketone Wafer Kyphoplasty with StaXx FX" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/32/7/1295" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: EPFs sustained during VCFs degrade the disk's ability to develop IDP under load. This inability to develop pressure in combination with residual kyphotic deformity increases the risk for adjacent vertebral fractures. We tested the hypothesis that StaXx FX reduces kyphosis and endplate deformity following vertebral compression fracture, restoring disk mechanics.

MATERIALS AND METHODS: Eight thoracolumbar, 5-vertebrae segments were tested. A void was selectively created in the middle vertebra. The specimens were compressed until EPF and to a grade I–II VCF. PEEK wafer kyphoplasty was then performed. The specimens were then tested in flexion-extension (±6 Nm) under 400-N preload intact, after EPF, VCF, and kyphoplasty. Endplate deformity, kyphosis, and IDP adjacent to the fractured body were measured.

RESULTS: Vertebral body height at the point of maximal endplate deformity decreased after EPF and VCF and was partially corrected after StaXx FX, remaining less than intact ( P = .047). Anterior vertebral height decreased after VCF ( P = .002) and was partially restored with StaXx FX, remaining less than intact ( P = .015). Vertebral kyphosis increased after VCF ( P &lt; .001) and reduced after StaXx FX, remaining greater than intact ( P = .03). EPF reduced IDP in the affected disk in compression-flexion loading ( P &lt; .001), which was restored after StaXx FX ( P = 1.0). IDP in the unaffected disk did not change during testing ( P &gt; .3).

CONCLUSIONS: StaXx FX reduced endplate deformity and kyphosis, and significantly increased anterior height following VCF. Although height and kyphosis were not fully corrected, the disk's ability to pressurize under load was restored.

EPF
:   endplate fracture
IDP
:   intradiskal pressure
PEEK
:   polyetherether-ketone
VCF
:   vertebral compression fracture" />
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">S.M. Renner</span>, <span class="highwire-citation-author" data-delta="1">P.P. Tsitsopoulos</span>, <span class="highwire-citation-author" data-delta="2">A.T. Dimitriadis</span>, <span class="highwire-citation-author" data-delta="3">L.I. Voronov</span>, <span class="highwire-citation-author" data-delta="4">R.M. Havey</span>, <span class="highwire-citation-author" data-delta="5">G. Carandang</span>, <span class="highwire-citation-author" data-delta="6">B. McIntosh</span>, <span class="highwire-citation-author" data-delta="7">C. Carson</span>, <span class="highwire-citation-author" data-delta="8">D. Ty</span>, <span class="highwire-citation-author" data-delta="9">J.G. Ringelstein</span> and <span class="highwire-citation-author" data-delta="10">A.G. Patwardhan</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">August 2011,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1295-1300; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A2484 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-11418--61604808493" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">S.M. Renner </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.M.%2BRenner%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Renner%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AS.M.%2BRenner%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">P.P. 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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" xmlns:xhtml="http://www.w3.org/1999/xhtml" class="section ref-list" id="ref-list-1"><h2>References</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1. in text" id="ref-1">↵</a>

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<div class="cit ref-cit ref-journal" id="cit-32.7.1295.3" data-doi="10.1007/s00586-007-0308-z"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Taylor</span>  <span class="cit-name-given-names">RS</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Fritzell</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Taylor</span>  <span class="cit-name-given-names">RJ</span></span></li></ol><cite>. <span class="cit-article-title">Balloon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis</span>. <abbr class="cit-jnl-abbrev">Eur Spine J</abbr> <span class="cit-pub-date">2007</span>;<span class="cit-vol">16</span>:<span class="cit-fpage">1085</span>–<span class="cit-lpage">100</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00586-007-0308-z&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=17277923&amp;link_type=MED&amp;atom=%2Fajnr%2F32%2F7%2F1295.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000248834000002&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><span class="ref-label">4.</span><a class="rev-xref-ref" href="#xref-ref-4-1" title="View reference 4. in text" id="ref-4">↵</a>

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<div class="cit ref-cit ref-journal" id="cit-32.7.1295.6" data-doi="10.1001/jama.285.3.320"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Lindsay</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Silverman</span>  <span class="cit-name-given-names">SL</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cooper</span>  <span class="cit-name-given-names">C</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Risk of new vertebral fracture in the year following a fracture</span>. <abbr class="cit-jnl-abbrev">JAMA</abbr> <span class="cit-pub-date">2001</span>;<span class="cit-vol">285</span>:<span class="cit-fpage">320</span>–<span class="cit-lpage">23</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1001/jama.285.3.320&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=11176842&amp;link_type=MED&amp;atom=%2Fajnr%2F32%2F7%2F1295.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000166324300023&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><span class="ref-label">7.</span><a class="rev-xref-ref" href="#xref-ref-7-1" title="View reference 7. in text" id="ref-7">↵</a>

<div class="cit ref-cit ref-journal" id="cit-32.7.1295.7" data-doi="10.1007/s001980050218"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Melton</span>  <span class="cit-name-given-names">LJ</span>  <span class="cit-name-suffix">3rd</span>.</span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Atkinson</span>  <span class="cit-name-given-names">EJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cooper</span>  <span class="cit-name-given-names">C</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Vertebral fractures predict subsequent fractures</span>. <abbr class="cit-jnl-abbrev">Osteoporos Int</abbr> <span class="cit-pub-date">1999</span>;<span class="cit-vol">10</span>:<span class="cit-fpage">214</span>–<span class="cit-lpage">21</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s001980050218&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=10525713&amp;link_type=MED&amp;atom=%2Fajnr%2F32%2F7%2F1295.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000083069800006&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><span class="ref-label">8.</span><a class="rev-xref-ref" href="#xref-ref-8-1" title="View reference 8. in text" id="ref-8">↵</a>

<div class="cit ref-cit ref-journal" id="cit-32.7.1295.8" data-doi="10.1007/BF01623272"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Ross</span>  <span class="cit-name-given-names">PD</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Genant</span>  <span class="cit-name-given-names">HK</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Davis</span>  <span class="cit-name-given-names">JW</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Predicting vertebral fracture incidence from prevalent fractures and bone density among non-black, osteoporotic women</span>. <abbr class="cit-jnl-abbrev">Osteoporos Int</abbr> <span class="cit-pub-date">1993</span>;<span class="cit-vol">3</span>:<span class="cit-fpage">120</span>–<span class="cit-lpage">26</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/BF01623272&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=8481587&amp;link_type=MED&amp;atom=%2Fajnr%2F32%2F7%2F1295.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1993KZ33100002&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div></li><li><span class="ref-label">9.</span><a class="rev-xref-ref" href="#xref-ref-9-1" title="View reference 9. in text" id="ref-9">↵</a>

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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 32</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 7 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Aug 2011 </div></div>
      
      
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      <div class="highwire-cite-title">Restoration of Spinal Alignment and Disk Mechanics following Polyetheretherketone Wafer Kyphoplasty with StaXx FX</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">S.M.</span> <span class="nlm-surname">Renner</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">P.P.</span> <span class="nlm-surname">Tsitsopoulos</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.T.</span> <span class="nlm-surname">Dimitriadis</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">L.I.</span> <span class="nlm-surname">Voronov</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">R.M.</span> <span class="nlm-surname">Havey</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Carandang</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">B.</span> <span class="nlm-surname">McIntosh</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Carson</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">D.</span> <span class="nlm-surname">Ty</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">J.G.</span> <span class="nlm-surname">Ringelstein</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">A.G.</span> <span class="nlm-surname">Patwardhan</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2011, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1295-1300; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2484 </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">S.M.</span> <span class="nlm-surname">Renner</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">P.P.</span> <span class="nlm-surname">Tsitsopoulos</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.T.</span> <span class="nlm-surname">Dimitriadis</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">L.I.</span> <span class="nlm-surname">Voronov</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">R.M.</span> <span class="nlm-surname">Havey</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Carandang</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">B.</span> <span class="nlm-surname">McIntosh</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Carson</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">D.</span> <span class="nlm-surname">Ty</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">J.G.</span> <span class="nlm-surname">Ringelstein</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">A.G.</span> <span class="nlm-surname">Patwardhan</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2011, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">32 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1295-1300; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2484 </span></div>
  
  
  
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