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<meta name="DC.Title" content="A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility" />
<meta name="DC.Identifier" content="10.3174/ajnr.A2789" />
<meta name="DC.Date" content="2012-03-01" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: To our knowledge, no reproducible animal model of a giant bifurcation type aneurysm has been described. It was our aim to develop a 1-stage and reproducible model of a venous pouch giant aneurysm in canines.

MATERIALS AND METHODS: Nine canines were involved. Bilateral CCAs were exposed. The left CCA was divided and its distal segment was swung to the right side. Using the right CCA and the distal segment of the left CCA, either a bifurcation or a terminal arterial structure was constructed. Bilateral external jugular veins were also exposed. A 30-mm vein segment was harvested from each side. Each vein graft was split and unfolded to make 2 venous sheets. These sheets were then joined top-to-bottom so as to form a single cylinder in such a way that original adventitial side of the venous sheets was on the exterior surface. In 2 instances, pieces of polytetrafluoroethylene were employed along with the venous sheets. The combined vein graft was then incorporated into the arterial anastomosis. Lastly, the top of the venous pouch was closed. No medications for anticoagulant or antiplatelet were used throughout the study period. Follow-up imaging studies were performed.

RESULTS: It took 2.5 hours on average for 2 operators to create an aneurysm. Eight of the 9 aneurysms were patent at follow-up. The cause of the spontaneous thrombosis was unclear despite autopsy. All the aneurysms had a maximum diameter &gt;20 mm.

CONCLUSIONS: We demonstrated and illustrated a 1-stage and reproducible procedure to create a model of a venous pouch bifurcation giant aneurysm in canines.

CCA
:   common carotid artery
EJV
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IA
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PTFE
:   polytetrafluoroethylene
VOR
:   volume to the area of the ostium" />
<meta name="DC.Contributor" content="R. Ysuda" />
<meta name="DC.Contributor" content="C.M. Strother" />
<meta name="DC.Contributor" content="B. Aagaard-Kienitz" />
<meta name="DC.Contributor" content="K. Pulfer" />
<meta name="DC.Contributor" content="D. Consigny" />
<meta name="article:published_time" content="2012-03-01" />
<meta name="article:section" content="Interventional" />
<meta name="citation_title" content="A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;To our knowledge, no reproducible animal model of a giant bifurcation type aneurysm has been described. It was our aim to develop a 1-stage and reproducible model of a venous pouch giant aneurysm in canines.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Nine canines were involved. Bilateral CCAs were exposed. The left CCA was divided and its distal segment was swung to the right side. Using the right CCA and the distal segment of the left CCA, either a bifurcation or a terminal arterial structure was constructed. Bilateral external jugular veins were also exposed. A 30-mm vein segment was harvested from each side. Each vein graft was split and unfolded to make 2 venous sheets. These sheets were then joined top-to-bottom so as to form a single cylinder in such a way that original adventitial side of the venous sheets was on the exterior surface. In 2 instances, pieces of polytetrafluoroethylene were employed along with the venous sheets. The combined vein graft was then incorporated into the arterial anastomosis. Lastly, the top of the venous pouch was closed. No medications for anticoagulant or antiplatelet were used throughout the study period. Follow-up imaging studies were performed.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;It took 2.5 hours on average for 2 operators to create an aneurysm. Eight of the 9 aneurysms were patent at follow-up. The cause of the spontaneous thrombosis was unclear despite autopsy. All the aneurysms had a maximum diameter &amp;gt;20 mm.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;We demonstrated and illustrated a 1-stage and reproducible procedure to create a model of a venous pouch bifurcation giant aneurysm in canines.&lt;/p&gt;" />
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<meta name="twitter:title" content="A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: To our knowledge, no reproducible animal model of a giant bifurcation type aneurysm has been described. It was our aim to develop a 1-stage and reproducible model of a venous pouch giant aneurysm in canines.

MATERIALS AND METHODS: Nine canines were involved. Bilateral CCAs were exposed. The left CCA was divided and its distal segment was swung to the right side. Using the right CCA and the distal segment of the left CCA, either a bifurcation or a terminal arterial structure was constructed. Bilateral external jugular veins were also exposed. A 30-mm vein segment was harvested from each side. Each vein graft was split and unfolded to make 2 venous sheets. These sheets were then joined top-to-bottom so as to form a single cylinder in such a way that original adventitial side of the venous sheets was on the exterior surface. In 2 instances, pieces of polytetrafluoroethylene were employed along with the venous sheets. The combined vein graft was then incorporated into the arterial anastomosis. Lastly, the top of the venous pouch was closed. No medications for anticoagulant or antiplatelet were used throughout the study period. Follow-up imaging studies were performed.

RESULTS: It took 2.5 hours on average for 2 operators to create an aneurysm. Eight of the 9 aneurysms were patent at follow-up. The cause of the spontaneous thrombosis was unclear despite autopsy. All the aneurysms had a maximum diameter &gt;20 mm.

CONCLUSIONS: We demonstrated and illustrated a 1-stage and reproducible procedure to create a model of a venous pouch bifurcation giant aneurysm in canines.

CCA
:   common carotid artery
EJV
:   external jugular vein
IA
:   intra-arterial
PTFE
:   polytetrafluoroethylene
VOR
:   volume to the area of the ostium" />
<meta name="og-title" property="og:title" content="A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/33/3/507" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: To our knowledge, no reproducible animal model of a giant bifurcation type aneurysm has been described. It was our aim to develop a 1-stage and reproducible model of a venous pouch giant aneurysm in canines.

MATERIALS AND METHODS: Nine canines were involved. Bilateral CCAs were exposed. The left CCA was divided and its distal segment was swung to the right side. Using the right CCA and the distal segment of the left CCA, either a bifurcation or a terminal arterial structure was constructed. Bilateral external jugular veins were also exposed. A 30-mm vein segment was harvested from each side. Each vein graft was split and unfolded to make 2 venous sheets. These sheets were then joined top-to-bottom so as to form a single cylinder in such a way that original adventitial side of the venous sheets was on the exterior surface. In 2 instances, pieces of polytetrafluoroethylene were employed along with the venous sheets. The combined vein graft was then incorporated into the arterial anastomosis. Lastly, the top of the venous pouch was closed. No medications for anticoagulant or antiplatelet were used throughout the study period. Follow-up imaging studies were performed.

RESULTS: It took 2.5 hours on average for 2 operators to create an aneurysm. Eight of the 9 aneurysms were patent at follow-up. The cause of the spontaneous thrombosis was unclear despite autopsy. All the aneurysms had a maximum diameter &gt;20 mm.

CONCLUSIONS: We demonstrated and illustrated a 1-stage and reproducible procedure to create a model of a venous pouch bifurcation giant aneurysm in canines.

CCA
:   common carotid artery
EJV
:   external jugular vein
IA
:   intra-arterial
PTFE
:   polytetrafluoroethylene
VOR
:   volume to the area of the ostium" />
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<div id="hw-article-author-popups-top-node-11849--6212116448" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">R. Ysuda </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BYsuda%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Ysuda%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AR.%2BYsuda%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">C.M. Strother </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.M.%2BStrother%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Strother%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AC.M.%2BStrother%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">B. Aagaard-Kienitz </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BAagaard-Kienitz%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Aagaard-Kienitz%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AB.%2BAagaard-Kienitz%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">K. Pulfer </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=K.%2BPulfer%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Pulfer%20K&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AK.%2BPulfer%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">D. Consigny </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.%2BConsigny%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Consigny%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AD.%2BConsigny%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div></div></div>  </div>

  
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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" xmlns:xhtml="http://www.w3.org/1999/xhtml" class="section ref-list" id="ref-list-1"><h2>References</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1. in text" id="ref-1">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.1"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">German</span>  <span class="cit-name-given-names">WJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Black</span>  <span class="cit-name-given-names">SP</span></span></li></ol><cite>.
<span class="cit-article-title">Experimental production of carotid aneurysms</span>.
<abbr class="cit-jnl-abbrev">N Engl J Med</abbr>
<span class="cit-pub-date">1954</span>;
<span class="cit-vol">250</span>:
<span class="cit-fpage">104</span>–<span class="cit-lpage">06</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=13119853&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1954UH53700003&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">2.</span><a class="rev-xref-ref" href="#xref-ref-2-1" title="View reference 2. in text" id="ref-2">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.2"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Cawley</span>  <span class="cit-name-given-names">CM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dawson</span>  <span class="cit-name-given-names">RC</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Shengelaia</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Arterial saccular aneurysm model in the rabbit</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">1996</span>;
<span class="cit-vol">17</span>:
<span class="cit-fpage">1761</span>–<span class="cit-lpage">66</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiIxNy85LzE3NjEiO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvMzMvMy81MDcuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span></span></a></div></div>
</li><li><span class="ref-label">3.</span><a class="rev-xref-ref" href="#xref-ref-3-1" title="View reference 3. in text" id="ref-3">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.3"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Hashimoto</span>  <span class="cit-name-given-names">N</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Handa</span>  <span class="cit-name-given-names">H</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Hazama</span>  <span class="cit-name-given-names">F</span></span></li></ol><cite>.
<span class="cit-article-title">Experimentally induced cerebral aneurysms in rats</span>.
<abbr class="cit-jnl-abbrev">Surg Neurol</abbr>
<span class="cit-pub-date">1978</span>;
<span class="cit-vol">10</span>:
<span class="cit-fpage">3</span>–<span class="cit-lpage">8</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=684603&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=A1978FF07400001&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">4.</span><a class="rev-xref-ref" href="#xref-ref-4-1" title="View reference 4. in text" id="ref-4">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.4"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Massoud</span>  <span class="cit-name-given-names">TF</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ji</span>  <span class="cit-name-given-names">C</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Guglielmi</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Experimental models of bifurcation and terminal aneurysms: construction techniques in swine</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">1994</span>;
<span class="cit-vol">15</span>:
<span class="cit-fpage">938</span>–<span class="cit-lpage">44</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIxNS81LzkzOCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">5.</span><a class="rev-xref-ref" href="#xref-ref-5-1" title="View reference 5. in text" id="ref-5">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.5" data-doi="10.3174/ajnr.A1853"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Bouzeghrane</span>  <span class="cit-name-given-names">F</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Naggara</span>  <span class="cit-name-given-names">O</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kallmes</span>  <span class="cit-name-given-names">DF</span></span>, </li><li><span class="cit-etal">et al.</span>, </li><li><span class="cit-auth cit-collab">The International Consortium of Neuroendovascular Centres</span></li></ol><cite>.
<span class="cit-article-title">In vivo experimental intracranial aneurysm models: a systematic review</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2010</span>;
<span class="cit-vol">31</span>:
<span class="cit-fpage">418</span>–<span class="cit-lpage">23</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIzMS8zLzQxOCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">6.</span><a class="rev-xref-ref" href="#xref-ref-6-1" title="View reference 6. in text" id="ref-6">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.6"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Cloft</span>  <span class="cit-name-given-names">HJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Altes</span>  <span class="cit-name-given-names">TA</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Marx</span>  <span class="cit-name-given-names">WF</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Endovascular creation of an in vivo aneurysm model in rabbits</span>.
<abbr class="cit-jnl-abbrev">Radiology</abbr>
<span class="cit-pub-date">1999</span>;
<span class="cit-vol">213</span>:
<span class="cit-fpage">223</span>–<span class="cit-lpage">28</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10540666&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000082771900038&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">7.</span><a class="rev-xref-ref" href="#xref-ref-7-1" title="View reference 7. in text" id="ref-7">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.7" data-doi="10.2214/ajr.174.2.1740349"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Altes</span>  <span class="cit-name-given-names">TA</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cloft</span>  <span class="cit-name-given-names">HJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Short</span>  <span class="cit-name-given-names">JG</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">1999 ARRS Executive Council Award. Creation of saccular aneurysms in the rabbit: a model suitable for testing endovascular devices</span>.
<span class="cit-auth cit-collab">American Roentgen Ray Society</span>.
<abbr class="cit-jnl-abbrev">AJR Am Roentgenol</abbr>
<span class="cit-pub-date">2000</span>;
<span class="cit-vol">174</span>:
<span class="cit-fpage">349</span>–<span class="cit-lpage">54</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.2214/ajr.174.2.1740349&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=10658703&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000084885000013&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">8.</span><a class="rev-xref-ref" href="#xref-ref-8-1" title="View reference 8. in text" id="ref-8">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.8"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Dai</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ding</span>  <span class="cit-name-given-names">YH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kadirvel</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">A longitudinal immunohistochemical study of healing of experimental aneurysms after embolization with platinum coils</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2006</span>;
<span class="cit-vol">27</span>:
<span class="cit-fpage">736</span>–<span class="cit-lpage">41</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyNy80LzczNiI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">9.</span><a class="rev-xref-ref" href="#xref-ref-9-1" title="View reference 9. in text" id="ref-9">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.9"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Fujiwara</span>  <span class="cit-name-given-names">NH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kallmes</span>  <span class="cit-name-given-names">DF</span></span></li></ol><cite>.
<span class="cit-article-title">Healing response in elastase-induced aneurysms after embolization with a new platinum coil system</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2002</span>;
<span class="cit-vol">23</span>:
<span class="cit-fpage">1137</span>–<span class="cit-lpage">44</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiIyMy83LzExMzciO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvMzMvMy81MDcuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">10.</span><a class="rev-xref-ref" href="#xref-ref-10-1" title="View reference 10. in text" id="ref-10">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.10"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Fujiwara</span>  <span class="cit-name-given-names">NH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cloft</span>  <span class="cit-name-given-names">HJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Marx</span>  <span class="cit-name-given-names">WF</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Serial angiography in an elastase-induced aneurysm model in rabbits: evidence for progressive aneurysm enlargement after creation</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2001</span>;
<span class="cit-vol">22</span>:
<span class="cit-fpage">698</span>–<span class="cit-lpage">703</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyMi80LzY5OCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">11.</span><a class="rev-xref-ref" href="#xref-ref-11-1" title="View reference 11. in text" id="ref-11">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.11"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Ding</span>  <span class="cit-name-given-names">YH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dai</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Lewis</span>  <span class="cit-name-given-names">DA</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Long term-patency of elastase-induced aneurysm model in rabbits</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2006</span>;
<span class="cit-vol">27</span>:
<span class="cit-fpage">139</span>–<span class="cit-lpage">41</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyNy8xLzEzOSI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">12.</span><a class="rev-xref-ref" href="#xref-ref-12-1" title="View reference 12. in text" id="ref-12">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.12"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Graves</span>  <span class="cit-name-given-names">VB</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Partington</span>  <span class="cit-name-given-names">CR</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Rüfenacht</span>  <span class="cit-name-given-names">DA</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Treatment of carotid artery aneurysms with platinum coils: an experimental study in dogs</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">1990</span>;
<span class="cit-vol">11</span>:
<span class="cit-fpage">249</span>–<span class="cit-lpage">52</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIxMS8yLzI0OSI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">13.</span><a class="rev-xref-ref" href="#xref-ref-13-1" title="View reference 13. in text" id="ref-13">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.13" data-doi="10.1007/s00234-007-0302-5"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Turk</span>  <span class="cit-name-given-names">AS</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Luty</span>  <span class="cit-name-given-names">CM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Carr-Brendel</span>  <span class="cit-name-given-names">V</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Angiographic and histological comparison of canine bifurcation aneurysms treated with first generation Matrix and standard GDC coils</span>.
<abbr class="cit-jnl-abbrev">Neuroradiol</abbr>
<span class="cit-pub-date">2008</span>;
<span class="cit-vol">50</span>:
<span class="cit-fpage">57</span>–<span class="cit-lpage">65</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00234-007-0302-5&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=17899048&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">14.</span><a class="rev-xref-ref" href="#xref-ref-14-1" title="View reference 14. in text" id="ref-14">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.14"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Turk</span>  <span class="cit-name-given-names">AS</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Aagaard-Kienitz</span>  <span class="cit-name-given-names">B</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Niemann</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Natural history of the canine vein pouch aneurysm model</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2007</span>;
<span class="cit-vol">28</span>:
<span class="cit-fpage">531</span>–<span class="cit-lpage">32</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyOC8zLzUzMSI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">15.</span><a class="rev-xref-ref" href="#xref-ref-15-1" title="View reference 15. in text" id="ref-15">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.15" data-doi="10.3174/ajnr.A1046"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Tsumoto</span>  <span class="cit-name-given-names">T</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Song</span>  <span class="cit-name-given-names">JK</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Niimi</span>  <span class="cit-name-given-names">Y</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Interval change in size of venous pouch canine bifurcation aneurysms over 10-month period</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2008</span>;
<span class="cit-vol">29</span>:
<span class="cit-fpage">1067</span>–<span class="cit-lpage">70</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiIyOS82LzEwNjciO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvMzMvMy81MDcuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">16.</span><a class="rev-xref-ref" href="#xref-ref-16-1" title="View reference 16. in text" id="ref-16">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.16"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Kallmes</span>  <span class="cit-name-given-names">DF</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Altes</span>  <span class="cit-name-given-names">DA</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Vincent</span>  <span class="cit-name-given-names">DA</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Experimental side-wall aneurysms: a natural history study</span>.
<abbr class="cit-jnl-abbrev">Neuroradiol</abbr>
<span class="cit-pub-date">1999</span>;
<span class="cit-vol">441</span>:
<span class="cit-fpage">338</span>–<span class="cit-lpage">41</span></cite></div><div class="cit-extra"></div></div>
</li><li><span class="ref-label">17.</span><a class="rev-xref-ref" href="#xref-ref-17-1" title="View reference 17. in text" id="ref-17">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.17"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Parkinson</span>  <span class="cit-name-given-names">RJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Eddleman</span>  <span class="cit-name-given-names">CS</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Batjer</span>  <span class="cit-name-given-names">HH</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Giant intracranial aneurysms: endovascular challenges</span>.
<abbr class="cit-jnl-abbrev">Neurosurgery</abbr>
<span class="cit-pub-date">2008</span>;
<span class="cit-vol">62</span>:
<span class="cit-fpage">1336</span>–<span class="cit-lpage">45</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=18695553&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000258226600073&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">18.</span><a class="rev-xref-ref" href="#xref-ref-18-1" title="View reference 18. in text" id="ref-18">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.18" data-doi="10.1097/00006123-199910000-00013"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Gruber</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Killer</span>  <span class="cit-name-given-names">M</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Bavinski</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Clinical angiographic results of endosaccular coiling treatment of giant and very large intracranial aneurysms: a 7-year, single-center experience</span>.
<abbr class="cit-jnl-abbrev">Neurosurgery</abbr>
<span class="cit-pub-date">1999</span>;
<span class="cit-vol">45</span>:
<span class="cit-fpage">793</span>–<span class="cit-lpage">803</span>;
<span class="cit-comment">discussion 803–04</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1097/00006123-199910000-00013&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=10515473&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000082932700029&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">19.</span><a class="rev-xref-ref" href="#xref-ref-19-1" title="View reference 19. in text" id="ref-19">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.19" data-doi="10.1007/978-3-7091-8975-7_10"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Battaglia</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Pasqualin</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Da Pian</span>  <span class="cit-name-given-names">R</span></span></li></ol><cite>.
<span class="cit-article-title">Italian Cooperative Study on Giant Intracranial Aneurysms: Part 1—study design and clinical data</span>.
<abbr class="cit-jnl-abbrev">Acta Neurochir Suppl (Wien)</abbr>
<span class="cit-pub-date">1988</span>;
<span class="cit-vol">42</span>:
<span class="cit-fpage">49</span>–<span class="cit-lpage">52</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/978-3-7091-8975-7_10&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=3055833&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">20.</span><a class="rev-xref-ref" href="#xref-ref-20-1" title="View reference 20. in text" id="ref-20">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.20"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Ding</span>  <span class="cit-name-given-names">YH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dai</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Danielson</span>  <span class="cit-name-given-names">MA</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Control of aneurysm volume by adjusting the position of ligation during creation of elastase aneurysms: a prospective study</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2007</span>;
<span class="cit-vol">28</span>:
<span class="cit-fpage">857</span>–<span class="cit-lpage">59</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIyOC81Lzg1NyI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">21.</span><a class="rev-xref-ref" href="#xref-ref-21-1" title="View reference 21. in text" id="ref-21">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.21" data-doi="10.3174/ajnr.A2205"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Ding</span>  <span class="cit-name-given-names">Y</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dai</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kadirvel</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Creation of large elastase-induced aneurysms: presurgical arterial remodeling using arteriovenous fistulas</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">2010</span>;
<span class="cit-vol">31</span>:
<span class="cit-fpage">1935</span>–<span class="cit-lpage">37</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czoxMDoiMzEvMTAvMTkzNSI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">22.</span><a class="rev-xref-ref" href="#xref-ref-22-1" title="View reference 22. in text" id="ref-22">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.22" data-doi="10.1016/0090-3019(84)90221-0"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Varsos</span>  <span class="cit-name-given-names">V</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Heros</span>  <span class="cit-name-given-names">RC</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">DeBrun</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Construction of experimental “giant” aneurysms</span>.
<abbr class="cit-jnl-abbrev">Surg Neurol</abbr>
<span class="cit-pub-date">1984</span>;
<span class="cit-vol">22</span>:
<span class="cit-fpage">17</span>–<span class="cit-lpage">20</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/0090-3019(84)90221-0&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=6729684&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">23.</span><a class="rev-xref-ref" href="#xref-ref-23-1" title="View reference 23. in text" id="ref-23">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.23"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Debrun</span>  <span class="cit-name-given-names">GM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Varsos</span>  <span class="cit-name-given-names">V</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Liszczak</span>  <span class="cit-name-given-names">TM</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Obliteration of experimental aneurysms in dogs with isobutyl-cyanoacrylate</span>.
<abbr class="cit-jnl-abbrev">J Neurosurg</abbr>
<span class="cit-pub-date">1984</span>;
<span class="cit-vol">61</span>:
<span class="cit-fpage">37</span>–<span class="cit-lpage">43</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=6726409&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">24.</span><a class="rev-xref-ref" href="#xref-ref-24-1" title="View reference 24. in text" id="ref-24">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.24"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Kerber</span>  <span class="cit-name-given-names">CW</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cromwell</span>  <span class="cit-name-given-names">LD</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Zanetti</span>  <span class="cit-name-given-names">PH</span></span></li></ol><cite>.
<span class="cit-article-title">Experimental carotid aneurysms: Part 2. Endovascular treatment with cyanoacrylate</span>.
<abbr class="cit-jnl-abbrev">Neurosurgery</abbr>
<span class="cit-pub-date">1985</span>;
<span class="cit-vol">16</span>:
<span class="cit-fpage">13</span>–<span class="cit-lpage">17</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=3974809&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">25.</span><a class="rev-xref-ref" href="#xref-ref-25-1" title="View reference 25. in text" id="ref-25">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.25" data-doi="10.1016/0090-3019(91)90155-3"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Yapor</span>  <span class="cit-name-given-names">W</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Jafar</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Crowell</span>  <span class="cit-name-given-names">RM</span></span></li></ol><cite>.
<span class="cit-article-title">One-stage construction of giant experimental aneurysms in dogs</span>.
<abbr class="cit-jnl-abbrev">Surg Neurol</abbr>
<span class="cit-pub-date">1991</span>;
<span class="cit-vol">36</span>:
<span class="cit-fpage">426</span>–<span class="cit-lpage">30</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/0090-3019(91)90155-3&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=1759181&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">26.</span><a class="rev-xref-ref" href="#xref-ref-26-1" title="View reference 26. in text" id="ref-26">↵</a>

<div class="cit ref-cit ref-book" id="cit-33.3.507.26"><div class="cit-metadata"><ol class="duplicate"><li><span class="cit-ed"><span class="cit-name-surname">Awad</span>  <span class="cit-name-given-names">IA</span></span>, </li><li><span class="cit-ed"><span class="cit-name-surname">Barrow</span>  <span class="cit-name-given-names">AL</span></span></li></ol><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Anson</span>  <span class="cit-name-given-names">JA</span></span></li></ol><cite>.
<span class="cit-article-title">Epidemiology and natural history</span>. In:

<span class="cit-ed"><span class="cit-name-surname">Awad</span>  <span class="cit-name-given-names">IA</span></span>, 
<span class="cit-ed"><span class="cit-name-surname">Barrow</span>  <span class="cit-name-given-names">AL</span></span> eds.
<span class="cit-source">Giant Intracranial Aneurysms</span>.
<span class="cit-publ-loc">Park Ridge, IL</span>:
<span class="cit-publ-name">American Association of Neurological Surgeons</span>;
<span class="cit-pub-date">1995</span>:
<span class="cit-fpage">23</span>–<span class="cit-lpage">33</span></cite></div><div class="cit-extra"></div></div>
</li><li><span class="ref-label">27.</span><a class="rev-xref-ref" href="#xref-ref-27-1" title="View reference 27. in text" id="ref-27">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.27"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Graves</span>  <span class="cit-name-given-names">VB</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ahuja</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Strother</span>  <span class="cit-name-given-names">CM</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Canine model of terminal arterial aneurysm</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">1993</span>;
<span class="cit-vol">14</span>:
<span class="cit-fpage">801</span>–<span class="cit-lpage">03</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo4OiIxNC80LzgwMSI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci8zMy8zLzUwNy5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">28.</span><a class="rev-xref-ref" href="#xref-ref-28-1" title="View reference 28. in text" id="ref-28">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.28"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Strother</span>  <span class="cit-name-given-names">CM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Graves</span>  <span class="cit-name-given-names">VB</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Rappe</span>  <span class="cit-name-given-names">A</span></span></li></ol><cite>.
<span class="cit-article-title">Aneurysm hemodynamics: an experimental study</span>.
<abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr>
<span class="cit-pub-date">1992</span>;
<span class="cit-vol">13</span>:
<span class="cit-fpage">1089</span>–<span class="cit-lpage">95</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiIxMy80LzEwODkiO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvMzMvMy81MDcuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div>
</li><li><span class="ref-label">29.</span><a class="rev-xref-ref" href="#xref-ref-29-1" title="View reference 29. in text" id="ref-29">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.29" data-doi="10.1227/NEU.0b013e3182010ed0"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Yasuda</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Strother</span>  <span class="cit-name-given-names">CM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Taki</span>  <span class="cit-name-given-names">W</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">Aneurysm volume-to-ostium area ratio (VOR): a parameter useful in discriminating the rupture status of intracranial aneurysms</span>.
<abbr class="cit-jnl-abbrev">Neurosurgery</abbr>
<span class="cit-pub-date">2011</span>;
<span class="cit-vol">68</span>:
<span class="cit-fpage">310</span>–<span class="cit-lpage">18</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1227/NEU.0b013e3182010ed0&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=21135739&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li><li><span class="ref-label">30.</span><a class="rev-xref-ref" href="#xref-ref-30-1" title="View reference 30. in text" id="ref-30">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.30"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Black</span>  <span class="cit-name-given-names">SP</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">German</span>  <span class="cit-name-given-names">WJ</span></span></li></ol><cite>.
<span class="cit-article-title">Observations on the relationship between the volume and the size of the orifice of experimental aneurysms</span>.
<abbr class="cit-jnl-abbrev">J Neurosurg</abbr>
<span class="cit-pub-date">1960</span>;
<span class="cit-vol">17</span>:
<span class="cit-fpage">894</span>–<span class="cit-lpage">990</span></cite></div><div class="cit-extra"></div></div>
</li><li><span class="ref-label">31.</span><a class="rev-xref-ref" href="#xref-ref-31-1" title="View reference 31. in text" id="ref-31">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.31" data-doi="10.3171/jns.2005.103.4.0662"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Hassan</span>  <span class="cit-name-given-names">T</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Timofeev</span>  <span class="cit-name-given-names">EV</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Saito</span>  <span class="cit-name-given-names">T</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>.
<span class="cit-article-title">A proposed parent vessel geometry-based categorization of saccular intracranial aneurysms: computational flow dynamics analysis of the risk factors for lesion rupture</span>.
<abbr class="cit-jnl-abbrev">J Neurosurg</abbr>
<span class="cit-pub-date">2005</span>;
<span class="cit-vol">103</span>:
<span class="cit-fpage">662</span>–<span class="cit-lpage">80</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.3171/jns.2005.103.4.0662&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=16266049&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a><a href="/lookup/external-ref?access_num=000232385000014&amp;link_type=ISI" class="cit-ref-sprinkles cit-ref-sprinkles-newisilink cit-ref-sprinkles-webofscience"><span>Web of Science</span></a></div></div>
</li><li><span class="ref-label">32.</span><a class="rev-xref-ref" href="#xref-ref-32-1" title="View reference 32. in text" id="ref-32">↵</a>

<div class="cit ref-cit ref-journal" id="cit-33.3.507.32" data-doi="10.1016/j.jvs.2009.04.071"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">AbuRahma</span>  <span class="cit-name-given-names">AF</span></span></li></ol><cite>.
<span class="cit-article-title">Processes of care for carotid endarterectomy: surgical and anesthesia considerations</span>.
<abbr class="cit-jnl-abbrev">J Vasc Surg</abbr>
<span class="cit-pub-date">2009</span>;
<span class="cit-vol">50</span>:
<span class="cit-fpage">921</span>–<span class="cit-lpage">33</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.jvs.2009.04.071&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=19660899&amp;link_type=MED&amp;atom=%2Fajnr%2F33%2F3%2F507.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div>
</li></ol></div></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 33</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 3 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Mar 2012 </div></div>
      
      
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      <div class="highwire-cite-title">A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Ysuda</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">C.M.</span> <span class="nlm-surname">Strother</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Aagaard-Kienitz</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Pulfer</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">D.</span> <span class="nlm-surname">Consigny</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Mar 2012, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">507-512; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2789 </span></div>
  
  
  
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      <div class="highwire-cite-title">A Large and Giant Bifurcation Aneurysm Model in Canines: Proof of Feasibility</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Ysuda</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">C.M.</span> <span class="nlm-surname">Strother</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Aagaard-Kienitz</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Pulfer</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">D.</span> <span class="nlm-surname">Consigny</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Mar 2012, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">507-512; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2789 </span></div>
  
  
  
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