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    Corticospinal Tract MR Signal-Intensity Pseudonormalization on Magnetization Transfer Contrast Imaging: A Potential Pitfall in the Interpretation of the Advanced Compromise of Upper Motor Neurons in Amyotrophic Lateral Sclerosis | American Journal of Neuroradiology  
    



















    































    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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LetterLETTER

  
      

  
      
Corticospinal Tract MR Signal-Intensity Pseudonormalization on Magnetization Transfer Contrast Imaging: A Potential Pitfall in the Interpretation of the Advanced Compromise of Upper Motor Neurons in Amyotrophic Lateral Sclerosis
  
    	
A.J. da Rocha, A.C. Martins Maia and B.C. Oliveira Valério

  
    	
American Journal of Neuroradiology May 2012,  33 (5) E79-E80; DOI: https://doi.org/10.3174/ajnr.A3114 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
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    1. Carrara  G, 
    2. Carapelli  C, 
    3. Venturi  F, 
    4. et al
    . A distinct MR imaging phenotype in amyotrophic lateral sclerosis: correlation between T1 magnetization transfer contrast hyperintensity along the corticospinal tract and diffusion tensor imaging analysis. AJNR Am J Neuroradiol 2012;33:733–39
    Abstract/FREE Full Text
  2. 2.↵


    1. Charil  A, 
    2. Corbo  M, 
    3. Filippi  M, 
    4. et al
    . Structural and metabolic changes in the brain of patients with upper motor neuron disorders: a multiparametric MRI study. Amyotroph Lateral Scler 2009;10:269–79
    CrossRefPubMed
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    1. Agosta  F, 
    2. Chio  A, 
    3. Cosottini  M, 
    4. et al
    . The present and the future of neuroimaging in amyotrophic lateral sclerosis. AJNR Am J Neuroradiol 2010;31:1769–77
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    1. da Rocha  AJ, 
    2. Oliveira  AS, 
    3. Fonseca  RB, 
    4. et al
    . Detection of corticospinal tract compromise in amyotrophic lateral sclerosis with brain MR imaging: relevance of the T1-weighted spin-echo magnetization transfer contrast sequence. AJNR Am J Neuroradiol 2004;25:1509–15
    Abstract/FREE Full Text
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Corticospinal Tract MR Signal-Intensity Pseudonormalization on Magnetization Transfer Contrast Imaging: A Potential Pitfall in the Interpretation of the Advanced Compromise of Upper Motor Neurons in Amyotrophic Lateral Sclerosis
  
    	
A.J. da Rocha, A.C. Martins Maia, B.C. Oliveira Valério

  
    	
American Journal of Neuroradiology May 2012, 33 (5) E79-E80; DOI: 10.3174/ajnr.A3114 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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