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<meta name="DC.Title" content="Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study" />
<meta name="DC.Identifier" content="10.3174/ajnr.A3087" />
<meta name="DC.Date" content="2012-09-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2012 by American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Data on the association between vertebral endplate changes and low back pain are contradictory. This study was designed to assess whether this association exists among Southern European subjects.

MATERIALS AND METHODS: Patients in this study serving as cases were 35–50 years of age with low back pain lasting &gt;90 days, for whom a lumbar MR imaging had been prescribed. Controls were subjects 35–50 years of age, having a cranial MR imaging for headache with normal findings, and no history of clinically relevant LBP. Two hundred forty cases and 64 controls were recruited consecutively in the radiology services across 6 cities in Spain. Imaging findings and subject characteristics were gathered through previously validated instruments. Radiologists who interpreted MRI were blinded to the subject characteristics. A multivariate logistic regression model was developed to assess the association of vertebral endplate changes with LBP, adjusting for sex, age, body mass index, lifetime exposure to smoking, physical activity, disk degeneration, and the interaction between disk degeneration and vertebral endplate changes.

RESULTS: Vertebral endplate changes were found in 80.4% of the cases and in 87.5% of the controls. In the regression model, disk degeneration was the only variable showing a confounding effect. Results showed that after adjusting for disk degeneration, the presence of vertebral endplate changes is associated with the absence of chronic LBP (OR for LBP: 0.31; 95% CI, 0.10–0.95).

CONCLUSIONS: In Southern European subjects, vertebral endplate changes are not associated with chronic LBP.

BMI
:   body mass index
CI
:   confidence interval
LBP
:   low back pain
OR
:   odds ratio
RMQ
:   Roland-Morris Questionnaire
VAS
:   visual analog scale" />
<meta name="DC.Contributor" content="F.M. Kovacs" />
<meta name="DC.Contributor" content="E. Arana" />
<meta name="DC.Contributor" content="A. Royuela" />
<meta name="DC.Contributor" content="A. Estremera" />
<meta name="DC.Contributor" content="G. Amengual" />
<meta name="DC.Contributor" content="B. Asenjo" />
<meta name="DC.Contributor" content="H. Sarasíbar" />
<meta name="DC.Contributor" content="I. Galarraga" />
<meta name="DC.Contributor" content="A. Alonso" />
<meta name="DC.Contributor" content="C. Casillas" />
<meta name="DC.Contributor" content="A. Muriel" />
<meta name="DC.Contributor" content="C. Martínez" />
<meta name="DC.Contributor" content="V. Abraira" />
<meta name="article:published_time" content="2012-09-01" />
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<meta name="citation_title" content="Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Data on the association between vertebral endplate changes and low back pain are contradictory. This study was designed to assess whether this association exists among Southern European subjects.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Patients in this study serving as cases were 35–50 years of age with low back pain lasting &amp;gt;90 days, for whom a lumbar MR imaging had been prescribed. Controls were subjects 35–50 years of age, having a cranial MR imaging for headache with normal findings, and no history of clinically relevant LBP. Two hundred forty cases and 64 controls were recruited consecutively in the radiology services across 6 cities in Spain. Imaging findings and subject characteristics were gathered through previously validated instruments. Radiologists who interpreted MRI were blinded to the subject characteristics. A multivariate logistic regression model was developed to assess the association of vertebral endplate changes with LBP, adjusting for sex, age, body mass index, lifetime exposure to smoking, physical activity, disk degeneration, and the interaction between disk degeneration and vertebral endplate changes.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Vertebral endplate changes were found in 80.4% of the cases and in 87.5% of the controls. In the regression model, disk degeneration was the only variable showing a confounding effect. Results showed that after adjusting for disk degeneration, the presence of vertebral endplate changes is associated with the absence of chronic LBP (OR for LBP: 0.31; 95% CI, 0.10–0.95).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;In Southern European subjects, vertebral endplate changes are not associated with chronic LBP.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="F.M. Kovacs" />
<meta name="citation_author_institution" content="aFrom the Departamento Científico (F.M.K.)" />
<meta name="citation_author_institution" content="bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain" />
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<meta name="twitter:title" content="Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Data on the association between vertebral endplate changes and low back pain are contradictory. This study was designed to assess whether this association exists among Southern European subjects.

MATERIALS AND METHODS: Patients in this study serving as cases were 35–50 years of age with low back pain lasting &gt;90 days, for whom a lumbar MR imaging had been prescribed. Controls were subjects 35–50 years of age, having a cranial MR imaging for headache with normal findings, and no history of clinically relevant LBP. Two hundred forty cases and 64 controls were recruited consecutively in the radiology services across 6 cities in Spain. Imaging findings and subject characteristics were gathered through previously validated instruments. Radiologists who interpreted MRI were blinded to the subject characteristics. A multivariate logistic regression model was developed to assess the association of vertebral endplate changes with LBP, adjusting for sex, age, body mass index, lifetime exposure to smoking, physical activity, disk degeneration, and the interaction between disk degeneration and vertebral endplate changes.

RESULTS: Vertebral endplate changes were found in 80.4% of the cases and in 87.5% of the controls. In the regression model, disk degeneration was the only variable showing a confounding effect. Results showed that after adjusting for disk degeneration, the presence of vertebral endplate changes is associated with the absence of chronic LBP (OR for LBP: 0.31; 95% CI, 0.10–0.95).

CONCLUSIONS: In Southern European subjects, vertebral endplate changes are not associated with chronic LBP.

BMI
:   body mass index
CI
:   confidence interval
LBP
:   low back pain
OR
:   odds ratio
RMQ
:   Roland-Morris Questionnaire
VAS
:   visual analog scale" />
<meta name="og-title" property="og:title" content="Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/33/8/1519" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Data on the association between vertebral endplate changes and low back pain are contradictory. This study was designed to assess whether this association exists among Southern European subjects.

MATERIALS AND METHODS: Patients in this study serving as cases were 35–50 years of age with low back pain lasting &gt;90 days, for whom a lumbar MR imaging had been prescribed. Controls were subjects 35–50 years of age, having a cranial MR imaging for headache with normal findings, and no history of clinically relevant LBP. Two hundred forty cases and 64 controls were recruited consecutively in the radiology services across 6 cities in Spain. Imaging findings and subject characteristics were gathered through previously validated instruments. Radiologists who interpreted MRI were blinded to the subject characteristics. A multivariate logistic regression model was developed to assess the association of vertebral endplate changes with LBP, adjusting for sex, age, body mass index, lifetime exposure to smoking, physical activity, disk degeneration, and the interaction between disk degeneration and vertebral endplate changes.

RESULTS: Vertebral endplate changes were found in 80.4% of the cases and in 87.5% of the controls. In the regression model, disk degeneration was the only variable showing a confounding effect. Results showed that after adjusting for disk degeneration, the presence of vertebral endplate changes is associated with the absence of chronic LBP (OR for LBP: 0.31; 95% CI, 0.10–0.95).

CONCLUSIONS: In Southern European subjects, vertebral endplate changes are not associated with chronic LBP.

BMI
:   body mass index
CI
:   confidence interval
LBP
:   low back pain
OR
:   odds ratio
RMQ
:   Roland-Morris Questionnaire
VAS
:   visual analog scale" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node12058" data-node-nid="12058" id="top-node-12058--2289744841" data-pisa="ajnr;33/8/1519" data-pisa-master="ajnr;ajnr.A3087" data-apath="/ajnr/33/8/1519.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Spine</span></span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-series highwire-cite-metadata">F</span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">F.M. Kovacs</span>, <span class="highwire-citation-author" data-delta="1">E. Arana</span>, <span class="highwire-citation-author" data-delta="2">A. Royuela</span>, <span class="highwire-citation-author" data-delta="3">A. Estremera</span>, <span class="highwire-citation-author" data-delta="4">G. Amengual</span>, <span class="highwire-citation-author" data-delta="5">B. Asenjo</span>, <span class="highwire-citation-author" data-delta="6">H. Sarasíbar</span>, <span class="highwire-citation-author" data-delta="7">I. Galarraga</span>, <span class="highwire-citation-author" data-delta="8">A. Alonso</span>, <span class="highwire-citation-author" data-delta="9">C. Casillas</span>, <span class="highwire-citation-author" data-delta="10">A. Muriel</span>, <span class="highwire-citation-author" data-delta="11">C. Martínez</span> and <span class="highwire-citation-author" data-delta="12">V. Abraira</span> <span  class="highwire-citation-author last"><span class="nlm-on-behalf-of">for the Spanish Back Pain Research Network</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 2012,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1519-1524; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A3087 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-12058--2289744841" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">F.M. Kovacs </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>aFrom the Departamento Científico (F.M.K.)</div><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.M.%2BKovacs%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Kovacs%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AF.M.%2BKovacs%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">E. Arana </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>cServicio de Radiología (E.A.), Fundación Instituto Valenciano de Oncología, Valencia, Spain</div><div class='author-affiliation'>dFundación Instituto de Investigación en Servicios de Salud (E.A.), Valencia, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=E.%2BArana%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Arana%20E&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AE.%2BArana%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">A. Royuela </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>eConsorcio de Investigación Biomédica en Red especializado en Epidemiología y Salud Pública (A.R., V.A.), Instituto de Salud Carlos III, Madrid, Spain</div><div class='author-affiliation'>fUnidad de Bioestadística Clínica (A.R., H.S., A.M., V.A.), Hospital Ramón y Cajal, Madrid, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BRoyuela%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Royuela%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BRoyuela%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">A. Estremera </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>gHospital Son Llàtzer, (A.E., G.A., C.M.), Palma de Mallorca, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BEstremera%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Estremera%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BEstremera%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">G. Amengual </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>gHospital Son Llàtzer, (A.E., G.A., C.M.), Palma de Mallorca, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G.%2BAmengual%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Amengual%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AG.%2BAmengual%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">B. Asenjo </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>hHospital Carlos Haya (B.A.), Málaga, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BAsenjo%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Asenjo%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AB.%2BAsenjo%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">H. Sarasíbar </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>fUnidad de Bioestadística Clínica (A.R., H.S., A.M., V.A.), Hospital Ramón y Cajal, Madrid, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=H.%2BSaras%C3%ADbar%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Saras%C3%ADbar%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AH.%2BSaras%25C3%25ADbar%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">I. Galarraga </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>iHospital de Manacor (I.G.), Mallorca, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=I.%2BGalarraga%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Galarraga%20I&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AI.%2BGalarraga%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">A. Alonso </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>jFundación Jiménez Díaz Avda (A.A.), Madrid, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BAlonso%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Alonso%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BAlonso%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">C. Casillas </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>kInstituto de Traumatología Unión de Mutuas (C.C.), Castellón, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BCasillas%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Casillas%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AC.%2BCasillas%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-10"><div class="author-tooltip-name">A. Muriel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>fUnidad de Bioestadística Clínica (A.R., H.S., A.M., V.A.), Hospital Ramón y Cajal, Madrid, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BMuriel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Muriel%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BMuriel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-11"><div class="author-tooltip-name">C. Martínez </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>bSpanish Back Pain Research Network (F.M.K., E.A., A.R., A.E., G.A., B.A., H.S., I.G., A.A., C.C., A.M., C.M., V.A.), Fundación Kovacs, Palma de Mallorca, Spain</div><div class='author-affiliation'>gHospital Son Llàtzer, (A.E., G.A., C.M.), Palma de Mallorca, Spain</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BMart%C3%ADnez%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mart%C3%ADnez%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AC.%2BMart%25C3%25ADnez%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-12"><div class="author-tooltip-name">V. 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 33</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 8 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Sep 2012 </div></div>
      
      
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">F.M.</span> <span class="nlm-surname">Kovacs</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">E.</span> <span class="nlm-surname">Arana</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Royuela</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Estremera</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Amengual</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Asenjo</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">H.</span> <span class="nlm-surname">Sarasíbar</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Galarraga</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Alonso</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Casillas</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Muriel</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Martínez</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Abraira</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 2012, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1519-1524; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A3087 </span></div>
  
  
  
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      <div class="highwire-cite-title">Vertebral Endplate Changes Are Not Associated with Chronic Low Back Pain among Southern European Subjects: A Case Control Study</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">F.M.</span> <span class="nlm-surname">Kovacs</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">E.</span> <span class="nlm-surname">Arana</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Royuela</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Estremera</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Amengual</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Asenjo</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">H.</span> <span class="nlm-surname">Sarasíbar</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Galarraga</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Alonso</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Casillas</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Muriel</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Martínez</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Abraira</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Sep 2012, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1519-1524; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A3087 </span></div>
  
  
  
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