1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [55e5434e-de77-4457-9d0d-f4c5053482fe] => Array
        (
            [runtime-id] => 55e5434e-de77-4457-9d0d-f4c5053482fe
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [1e9d4159-26fd-408f-a571-9b0b80375f71] => Array
                        (
                            [runtime-id] => 1e9d4159-26fd-408f-a571-9b0b80375f71
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)
1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => FreeToRead
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [fa620329-befd-4f5a-9623-71b30662280e] => Array
        (
            [runtime-id] => fa620329-befd-4f5a-9623-71b30662280e
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => FreeToRead
            [privilege] => Array
                (
                    [a1346ce0-9f8e-4d72-a02f-217d2422e356] => Array
                        (
                            [runtime-id] => a1346ce0-9f8e-4d72-a02f-217d2422e356
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)
1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [55e5434e-de77-4457-9d0d-f4c5053482fe] => Array
        (
            [runtime-id] => 55e5434e-de77-4457-9d0d-f4c5053482fe
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [1e9d4159-26fd-408f-a571-9b0b80375f71] => Array
                        (
                            [runtime-id] => 1e9d4159-26fd-408f-a571-9b0b80375f71
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)
1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [55e5434e-de77-4457-9d0d-f4c5053482fe] => Array
        (
            [runtime-id] => 55e5434e-de77-4457-9d0d-f4c5053482fe
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [1e9d4159-26fd-408f-a571-9b0b80375f71] => Array
                        (
                            [runtime-id] => 1e9d4159-26fd-408f-a571-9b0b80375f71
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)
1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [55e5434e-de77-4457-9d0d-f4c5053482fe] => Array
        (
            [runtime-id] => 55e5434e-de77-4457-9d0d-f4c5053482fe
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [1e9d4159-26fd-408f-a571-9b0b80375f71] => Array
                        (
                            [runtime-id] => 1e9d4159-26fd-408f-a571-9b0b80375f71
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)
1naresh2naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

    [4d9e6914-5309-43cc-92fb-035dcdac445b] => Array
        (
            [runtime-id] => 4d9e6914-5309-43cc-92fb-035dcdac445b
            [type] => toll-free-key
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [7829c232-2a4b-4a32-a16c-acb6a615fa84] => Array
                        (
                            [runtime-id] => 7829c232-2a4b-4a32-a16c-acb6a615fa84
                            [type] => toll-free-key
                        )

                )

            [credentials] => Array
                (
                    [method] => toll-free-key
                    [value] => tf_ipsecsha;8fdb87cede3361c7577d385947bfe2703e76bee3
                )

        )

)


  
    






































    Table of Contents — March 01, 2013, 34 (3) | American Journal of Neuroradiology  
    
















    





















    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



    

  


  


  


  
  
  
  
  
  

  	      


    
      

    
  
    
        
    

  

    
                        

  

                
    

      

	  

		
		

			

			  

  
      
  
  

    

    
    
  
  
      
Table of Contents
  	
      
March 01, 2013; Volume 34,Issue 3 

  
  
   

  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
Editorials
  • Perspectives
    • 
  
  
      
      Editorials 
      
  
      
      
  
      Apples  
    	
      M. Castillo
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 479-480; DOI: https://doi.org/10.3174/ajnr.A3162 
      
  
  
  

      

Review Articles
Brain
  • 
  
  
      
    Brain 
    
  
      
    
  
      Automated Determination of Brain Parenchymal Fraction in Multiple Sclerosis  
    	
    M. Vågberg, T. Lindqvist, K. Ambarki, J.B.M. Warntjes, P. Sundström, R. Birgander and A. Svenningsson
    
  
    	
    American Journal of Neuroradiology March 2013, 34 (3) 498-504; DOI: https://doi.org/10.3174/ajnr.A3262 
    
  
  
  

    

  • 
  
  
      
    EDITOR'S CHOICEBrain 
    
  
      
    Open Access
    
  
      Apolipoprotein E ε4 Does Not Modulate Amyloid-β–Associated Neurodegeneration in Preclinical Alzheimer Disease  
    	
    R.S. Desikan, L.K. McEvoy, D. Holland, W.K. Thompson, J.B. Brewer, P.S. Aisen, O.A. Andreassen, B.T. Hyman, R.A. Sperling, A.M. Dale and for the Alzheimer's Disease Neuroimaging Initiative
    
  
    	
    American Journal of Neuroradiology March 2013, 34 (3) 505-510; DOI: https://doi.org/10.3174/ajnr.A3267 
    
  
    	
    

    These authors investigated the relationship between amyloid-β, phosphorylated tau, and apolipoprotein E in preclinical Alzheimer disease in 170 patients and controls who had serial imaging up to 3.5 years after the initial study. Global volumes as well as volumes in brain regions known to be involved in the chronic stages of the disease were assessed. Their results led them to propose that atrophy rates are primarily influenced by apolipoprotein E via amyloid-β mechanisms and that amyloid-β -associated neurodegeneration occurs only in the presence of phosphorylated tau.
    
  
  

    

  • Commentary
    • 
  
  
      
      Brain 
      
  
      
      
  
      The Role of Amyloid-β, tau, and Apolipoprotein E ε4 in Alzheimer Disease: How Is the Team Playing?  
    	
      M. Filippi, E. Canu and F. Agosta
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 511-512; DOI: https://doi.org/10.3174/ajnr.A3295 
      
  
  
  

      

    • 
  
  
      
      Brain 
      
  
      
      Open Access
      
  
      Contrast-Enhanced 3T High-Resolution MR Imaging in Symptomatic Atherosclerotic Basilar Artery Stenosis  
    	
      X. Lou, N. Ma, L. Ma and W.-J. Jiang
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 513-517; DOI: https://doi.org/10.3174/ajnr.A3241 
      
  
  
  

      

    • 
  
  
      
      EDITOR'S CHOICEBrain 
      
  
      
      Open Access
      
  
      Blood-Brain Barrier Disruption after Cardiac Surgery  
    	
      J.G. Merino, L.L. Latour, A. Tso, K.Y. Lee, D.W. Kang, L.A. Davis, R.M. Lazar, K.A. Horvath, P.J. Corso and S. Warach
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 518-523; DOI: https://doi.org/10.3174/ajnr.A3251 
      
  
    	
      

      To shed light on brain complications occurring after heart surgery, the authors assessed BBB disruption and DWI findings in half of their patients by imaging at 24 hours after surgery and 24–48 hours later. Additionally, postcontrast T1 images were obtained postoperatively at 2–4 days in the other half of the patients. Almost half the patients undergoing cardiac surgery had evidence of BBB abnormalities and three-quarters showed acute lesions on DWI after surgery. BBB disruption is more prevalent in the first 24 hours after surgery. These findings suggest that MR can be used as an imaging biomarker to assess therapies that may protect the BBB in patients undergoing heart surgery.
      
  
  

      

    • 
  
  
      
      Brain 
      
  
      
      
  
      Postoperative Transient Reduced Diffusion in the Ipsilateral Striatum and Thalamus  
    	
      K. Kamiya, N. Sato, Y. Nakata, K. Ito, Y. Kimura, M. Ota, A. Takahashi, H. Mori, A. Kunimatsu and K. Ohtomo
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 524-532; DOI: https://doi.org/10.3174/ajnr.A3242 
      
  
  
  

      

    • 
  
  
      
      EDITOR'S CHOICEBrain 
      
  
      
      
  
      Probabilistic Radiographic Atlas of Glioblastoma Phenotypes  
    	
      B.M. Ellingson, A. Lai, R.J. Harris, J.M. Selfridge, W.H. Yong, K. Das, W.B. Pope, P.L. Nghiemphu, H.V. Vinters, L.M. Liau, P.S. Mischel and T.F. Cloughesy
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 533-540; DOI: https://doi.org/10.3174/ajnr.A3253 
      
  
    	
      

      Images from over 500 patients with glioblastoma were used to build location atlases corresponding to genetic and biologic abnormalities as well as prognosis based on age. Most glioblastomas grew into the periventricular regions adjacent to the subventricular zone. MGMT promoter methylated tumors occurred more frequently in the left temporal lobe in young patients, in IDH1 mutant tumors, in those having the proneural gene expression subtype, and in tumors lacking loss of PTEN that occurred most frequently in the frontal lobe. MGMT methylated tumors with IDH1 mutation tended to occur in the left frontal lobe. EGFR amplified and EGFR variant 3-expressing tumors were found most frequently in the left temporal lobe. Tumors in the left temporal lobe were associated with favorable response to radiochemotherapy and increased survival.
      
  
  

      

    • 
  
  
      
      Brain 
      
  
      
      Open Access
      
  
      MR Imaging of Cerebral Extraventricular Neurocytoma: A Report of 9 Cases  
    	
      K. Liu, G. Wen, X.-F. Lv, Yan-Jia Deng, Yong-Jian Deng, G.-Q. Hou, X.-L. Zhang, L.-J. Han and J.-L. Ding
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 541-546; DOI: https://doi.org/10.3174/ajnr.A3264 
      
  
  
  

      

    • 
  
  
      
      Brain 
      
  
      
      
  
      The Role of the Occipital Artery in the Diagnosis of Intracranial Dural Arteriovenous Fistula Using Duplex Sonography  
    	
      B.-L. Tee, L.-K. Tsai, C.-C. Lai, S.-C. Tang, Y.-A. Chen, C.-L. Chen and J.-S. Jeng
      
  
    	
      American Journal of Neuroradiology March 2013, 34 (3) 547-551; DOI: https://doi.org/10.3174/ajnr.A3273 
      
  
  
  

      

Functional
Interventional
Extracranial Vascular
Head & Neck
Pediatrics
Spine
Technical Notes: (Online only)
Letters: (Online only)
  


  
  



  
      
  
  

     Back to top  


  
  



  
      
  
  

    
  


  
  



			

		

		
		

			

			  

  
        
In this issue

    
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



  


  
  



  
        
Jump to

    
  
  

    
  


  
  



  
      
  
  

    
  


  
  



			

		

	
	
 	
	
	


    

  



  

                
    

      

  

    

  
      
  
  

    


Advertisement