1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => FreeToRead
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)


  
    



































































































































    Multimodal MR Imaging (Diffusion, Perfusion, and Spectroscopy): Is It Possible to Distinguish Oligodendroglial Tumor Grade and 1p/19q Codeletion in the Pretherapeutic Diagnosis? | American Journal of Neuroradiology  
    

















    





























    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



    

  


  


  


  
  
  
  
  
  

  	      



          


    
      

    
  
    
        
    

  

    
                        

  

                
    

      

	  

		
		

			

			  

  
      
  
  

    

  
  
      
Research ArticleBrainE

  
      

  
      
Multimodal MR Imaging (Diffusion, Perfusion, and Spectroscopy): Is It Possible to Distinguish Oligodendroglial Tumor Grade and 1p/19q Codeletion in the Pretherapeutic Diagnosis?
  
    	
S. Fellah, D. Caudal, A.M. De Paula, P. Dory-Lautrec, D. Figarella-Branger, O. Chinot, P. Metellus, P.J. Cozzone, S. Confort-Gouny, B. Ghattas, V. Callot and N. Girard

  
    	
American Journal of Neuroradiology July 2013,  34 (7) 1326-1333; DOI: https://doi.org/10.3174/ajnr.A3352 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
REFERENCES
  1. 1.↵


    1. Jenkins  RB, 
    2. Blair  H, 
    3. Ballman  KV, 
    4. et al
    . A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res 2006;66:9852–61
    Abstract/FREE Full Text
  2. 2.↵


    1. Smith  JS, 
    2. Perry  A, 
    3. Borell  TJ, 
    4. et al
    . Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J Clin Oncol 2000;18:636–45
    Abstract/FREE Full Text
  3. 3.↵


    1. Walker  C, 
    2. Haylock  B, 
    3. Husband  D, 
    4. et al
    . Clinical use of genotype to predict chemosensitivity in oligodendroglial tumors. Neurology 2006;66:1661–67
    CrossRef
  4. 4.↵


    1. Sasaki  H, 
    2. Zlatescu  MC, 
    3. Betensky  RA, 
    4. et al
    . Histopathological-molecular genetic correlations in referral pathologist-diagnosed low-grade “oligodendroglioma”. J Neuropathol Exp Neurol 2002;61:58–63
    PubMedWeb of Science
  5. 5.↵


    1. Dean  BL, 
    2. Drayer  BP, 
    3. Bird  CR, 
    4. et al
    . Gliomas: classification with MR imaging. Radiology 1990;174:411–15
    CrossRefPubMedWeb of Science
  6. 6.↵


    1. Law  M, 
    2. Yang  S, 
    3. Wang  H, 
    4. et al
    . Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol 2003;24:1989–98
    Abstract/FREE Full Text
  7. 7.↵


    1. Jenkinson  MD, 
    2. Smith  TS, 
    3. Joyce  KA, 
    4. et al
    . Cerebral blood volume, genotype and chemosensitivity in oligodendroglial tumours. Neuroradiology 2006;48:703–13
    CrossRefPubMedWeb of Science
  8. 8.↵


    1. Law  M, 
    2. Yang  S, 
    3. Babb  JS, 
    4. et al
    . Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade. AJNR Am J Neuroradiol 2004;25:746–55
    Abstract/FREE Full Text
  9. 9.↵


    1. Stadlbauer  A, 
    2. Gruber  S, 
    3. Nimsky  C, 
    4. et al
    . Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging. Radiology 2006;238:958–69
    CrossRefPubMedWeb of Science
  10. 10.↵


    1. Jenkinson  MD, 
    2. Smith  TS, 
    3. Brodbelt  AR, 
    4. et al
    . Apparent diffusion coefficients in oligodendroglial tumors characterized by genotype. J Magn Reson Imaging 2007;26:1405–12
    CrossRefPubMed
  11. 11.↵


    1. Law  M, 
    2. Brodsky  JE, 
    3. Babb  J, 
    4. et al
    . High cerebral blood volume in human gliomas predicts deletion of chromosome 1p: preliminary results of molecular studies in gliomas with elevated perfusion. J Magn Reson Imaging 2007;25:1113–19
    CrossRefPubMed
  12. 12.↵


    1. Jenkinson  MD, 
    2. du Plessis  DG, 
    3. Smith  TS, 
    4. et al
    . Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI features. Brain 2006;129:1884–91
    Abstract/FREE Full Text
  13. 13.↵


    1. Jenkinson  MD, 
    2. Smith  TS, 
    3. Joyce  K, 
    4. et al
    . MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes. Neurology 2005;64:2085–89
    CrossRef
  14. 14.↵


    1. Kapoor  GS, 
    2. Gocke  TA, 
    3. Chawla  S, 
    4. et al
    . Magnetic resonance perfusion-weighted imaging defines angiogenic subtypes of oligodendroglioma according to 1p19q and EGFR status. J Neurooncol 2009;92:373–86
    CrossRefPubMed
  15. 15.↵


    1. Louis  DN, 
    2. Ohgaki  H, 
    3. Wiestler  OD, 
    4. et al
    . The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114:97–109
    CrossRefPubMedWeb of Science
  16. 16.↵


    1. Metellus  P, 
    2. Coulibaly  B, 
    3. Colin  C, 
    4. et al
    . Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis. Acta Neuropathol 2010;120:719–29
    CrossRefPubMedWeb of Science
  17. 17.↵


    1. Vanhamme  L, 
    2. van den Boogaart  A, 
    3. Van Huffel  S
    . Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997;129:35–43
    CrossRefPubMedWeb of Science
  18. 18.↵


    1. Le Fur  Y, 
    2. Nicoli  F, 
    3. Guye  M, 
    4. et al
    . Grid-free interactive and automated data processing for MR chemical shift imaging data. MAGMA 2010;23:23–30
    CrossRefPubMed
  19. 19.↵


    1. Wetzel  SG, 
    2. Cha  S, 
    3. Johnson  G, 
    4. et al
    . Relative cerebral blood volume measurements in intracranial mass lesions: interobserver and intraobserver reproducibility study. Radiology 2002;224:797–803
    CrossRefPubMedWeb of Science
  20. 20.↵


    1. Breiman  L
    . Random forests. Machine Learning 2001;45:5–32
    CrossRefWeb of Science
  21. 21.↵


    1. Möller-Hartmann  W, 
    2. Herminghaus  S, 
    3. Krings  T, 
    4. et al
    . Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. Neuroradiology 2002;44:371–81
    CrossRefPubMedWeb of Science
  22. 22.↵


    1. White  ML, 
    2. Zhang  Y, 
    3. Kirby  P, 
    4. et al
    . Can tumor contrast enhancement be used as a criterion for differentiating tumor grades of oligodendrogliomas? AJNR Am J Neuroradiol 2005;26:784–90
    Abstract/FREE Full Text
  23. 23.↵


    1. Megyesi  JF, 
    2. Kachur  E, 
    3. Lee  DH, 
    4. et al
    . Imaging correlates of molecular signatures in oligodendrogliomas. Clin Cancer Res 2004;10:4303–06
    Abstract/FREE Full Text
  24. 24.↵


    1. Zlatescu  MC, 
    2. TehraniYazdi  A, 
    3. Sasaki  H, 
    4. et al
    . Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Res 2001;61:6713–15
    Abstract/FREE Full Text
  25. 25.↵


    1. Hilario  A, 
    2. Ramos  A, 
    3. Perez-Nuñez  A, 
    4. et al
    . The added value of apparent diffusion coefficient to cerebral blood volume in the preoperative grading of diffuse gliomas. AJNR Am J Neuroradiol 2012;33:701–07
    Abstract/FREE Full Text
  26. 26.↵


    1. Whitmore  RG, 
    2. Krejza  J, 
    3. Kapoor  GS, 
    4. et al
    . Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging. J Neurosurg 2007;107:600–09
    CrossRefPubMedWeb of Science
  27. 27.↵


    1. Spampinato  MV, 
    2. Smith  JK, 
    3. Kwock  L, 
    4. et al
    . Cerebral blood volume measurements and proton MR spectroscopy in grading of oligodendroglial tumors. AJR Am J Roentgenol 2007;188:204–12
    CrossRefPubMedWeb of Science
  28. 28.↵


    1. Xu  M, 
    2. See  SJ, 
    3. Ng  WH, 
    4. et al
    . Comparison of magnetic resonance spectroscopy and perfusion-weighted imaging in presurgical grading of oligodendroglial tumors. Neurosurgery 2005;56:919–26; discussion 919–26
    PubMedWeb of Science
  29. 29.↵


    1. Chawla  S, 
    2. Wang  S, 
    3. Wolf  RL, 
    4. et al
    . Arterial spin-labeling and MR spectroscopy in the differentiation of gliomas. AJNR Am J Neuroradiol 2007;28:1683–89
    Abstract/FREE Full Text
  30. 30.↵


    1. Galanaud  D, 
    2. Nicoli  F, 
    3. Chinot  O, 
    4. et al
    . Noninvasive diagnostic assessment of brain tumors using combined in vivo MR imaging and spectroscopy. Magn Reson Med 2006;55:1236–45
    CrossRefPubMedWeb of Science
  31. 31.↵


    1. Smith  JK, 
    2. Castillo  M, 
    3. Kwock  L
    . MR spectroscopy of brain tumors. Magn Reson Imaging Clin N Am 2003;11:415–29, v–vi
    CrossRefPubMed
  32. 32.↵


    1. Gupta  RK, 
    2. Cloughesy  TF, 
    3. Sinha  U, 
    4. et al
    . Relationships between choline magnetic resonance spectroscopy, apparent diffusion coefficient and quantitative histopathology in human glioma. J Neurooncol 2000;50:215–26
    CrossRefPubMed
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

     Back to top  


  
  



			

		

		
		

			

			  

  
        
In this issue

    
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    


Advertisement



  



  


  
  



  



  


  
  



  
      
  
  

    

	  
  

		

          

            

  
      
  
  

     Print  


  
  



  
      
  
  

     Download PDF  


  
  



  
      
  
  

    
 Email Article
  


  
  



  
      
  
  

    
 Citation Tools
  


  
  



          

        

        
        

          

            



  
      
  
  

    

  

    

  
      
  
  

    

  
  
  
  
      
Multimodal MR Imaging (Diffusion, Perfusion, and Spectroscopy): Is It Possible to Distinguish Oligodendroglial Tumor Grade and 1p/19q Codeletion in the Pretherapeutic Diagnosis?
  
    	
S. Fellah, D. Caudal, A.M. De Paula, P. Dory-Lautrec, D. Figarella-Branger, O. Chinot, P. Metellus, P.J. Cozzone, S. Confort-Gouny, B. Ghattas, V. Callot, N. Girard

  
    	
American Journal of Neuroradiology Jul 2013, 34 (7) 1326-1333; DOI: 10.3174/ajnr.A3352 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  


  
  



  



  


  
  



  
      
  
  

    
  


  
  



          

        

	
 	
	
	


  


  
  



  
      
  
  

    
              Purchase  


  
  



  
        
Jump to section

    
  
  

    
  


  
  



  
      
  
  

    
  


  
  



			

		

	
	
 	
	
	


    

  



  

                
    

      

  

    

  
      
  
  

    


Advertisement