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<meta name="DC.Title" content="Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements" />
<meta name="DC.Identifier" content="10.3174/ajnr.A3624" />
<meta name="DC.Date" content="2014-01-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2014 by American Journal of Neuroradiology. Indicates open access to non-subscribers at www.ajnr.org" />
<meta name="DC.AccessRights" content="open-access" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Computational fluid dynamics modeling is useful in the study of the hemodynamic environment of cerebral aneurysms, but patient-specific measurements of boundary conditions, such as blood flow velocity and pressure, have not been previously applied to the study of flow-diverting stents. We integrated patient-specific intravascular blood flow velocity and pressure measurements into computational models of aneurysms before and after treatment with flow-diverting stents to determine stent effects on aneurysm hemodynamics.

MATERIALS AND METHODS: Blood flow velocity and pressure were measured in peri-aneurysmal locations by use of an intravascular dual-sensor pressure and Doppler velocity guidewire before and after flow-diverting stent treatment of 4 unruptured cerebral aneurysms. These measurements defined inflow and outflow boundary conditions for computational models. Intra-aneurysmal flow rates, wall shear stress, and wall shear stress gradient were calculated.

RESULTS: Measurements of inflow velocity and outflow pressure were successful in all 4 patients. Computational models incorporating these measurements demonstrated significant reductions in intra-aneurysmal wall shear stress and wall shear stress gradient and a trend in reduced intra-aneurysmal blood flow.

CONCLUSIONS: Integration of intravascular dual-sensor guidewire measurements of blood flow velocity and blood pressure provided patient-specific computational models of cerebral aneurysms. Aneurysm treatment with flow-diverting stents reduces blood flow and hemodynamic shear stress in the aneurysm dome.

CFD
:   computational fluid dynamics
WSS
:   wall shear stress
WSSG
:   wall shear stress gradient
TCD
:   transcranial Doppler ultrasonography
pcMRA
:   phase-contrast MRA" />
<meta name="DC.Contributor" content="M.R. Levitt" />
<meta name="DC.Contributor" content="P.M. McGah" />
<meta name="DC.Contributor" content="A. Aliseda" />
<meta name="DC.Contributor" content="P.D. Mourad" />
<meta name="DC.Contributor" content="J.D. Nerva" />
<meta name="DC.Contributor" content="S.S. Vaidya" />
<meta name="DC.Contributor" content="R.P. Morton" />
<meta name="DC.Contributor" content="B.V. Ghodke" />
<meta name="DC.Contributor" content="L.J. Kim" />
<meta name="article:published_time" content="2014-01-01" />
<meta name="article:section" content="Interventional" />
<meta name="citation_title" content="Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Computational fluid dynamics modeling is useful in the study of the hemodynamic environment of cerebral aneurysms, but patient-specific measurements of boundary conditions, such as blood flow velocity and pressure, have not been previously applied to the study of flow-diverting stents. We integrated patient-specific intravascular blood flow velocity and pressure measurements into computational models of aneurysms before and after treatment with flow-diverting stents to determine stent effects on aneurysm hemodynamics.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Blood flow velocity and pressure were measured in peri-aneurysmal locations by use of an intravascular dual-sensor pressure and Doppler velocity guidewire before and after flow-diverting stent treatment of 4 unruptured cerebral aneurysms. These measurements defined inflow and outflow boundary conditions for computational models. Intra-aneurysmal flow rates, wall shear stress, and wall shear stress gradient were calculated.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Measurements of inflow velocity and outflow pressure were successful in all 4 patients. Computational models incorporating these measurements demonstrated significant reductions in intra-aneurysmal wall shear stress and wall shear stress gradient and a trend in reduced intra-aneurysmal blood flow.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Integration of intravascular dual-sensor guidewire measurements of blood flow velocity and blood pressure provided patient-specific computational models of cerebral aneurysms. Aneurysm treatment with flow-diverting stents reduces blood flow and hemodynamic shear stress in the aneurysm dome.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="2014/01/01" />
<meta name="citation_mjid" content="ajnr;35/1/143" />
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<meta name="citation_issn" content="0195-6108" />
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<meta name="citation_doi" content="10.3174/ajnr.A3624" />
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<meta name="citation_author" content="M.R. Levitt" />
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<meta name="citation_author" content="L.J. Kim" />
<meta name="citation_author_institution" content="aFrom the Departments of Neurological Surgery (M.R.L., P.D.M., J.D.N., R.P.M., B.V.G., L.J.K.)" />
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<meta name="citation_reference" content="citation_journal_title=Neurosurgery;citation_author=P. Lylyk;citation_author=C. Miranda;citation_author=R. Ceratto;citation_title=Curative endovascular reconstruction of cerebral aneurysms with the Pipeline embolization device: the Buenos Aires experience;citation_pages=632-42;citation_volume=64;citation_year=2009;citation_pmid=19349825;citation_doi=10.1227/01.NEU.0000339109.98070.65" />
<meta name="citation_reference" content="citation_journal_title=Med Eng Phys;citation_author=Y. Zhang;citation_author=W. Chong;citation_author=Y. Qian;citation_title=Investigation of intracranial aneurysm hemodynamics following flow diverter stent treatment;citation_pages=608-15;citation_volume=35;citation_year=2013;citation_pmid=22884174;citation_doi=10.1016/j.medengphy.2012.07.005" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=W. McAuliffe;citation_author=V. Wycoco;citation_author=H. Rice;citation_title=Immediate and midterm results following treatment of unruptured intracranial aneurysms with the Pipeline embolization device;citation_volume=33;citation_year=2012;citation_pmid=21979492;citation_doi=10.3174/ajnr.A2727" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=CJ. O'Kelly;citation_author=J. Spears;citation_author=M. Chow;citation_title=Canadian experience with the Pipeline embolization device for repair of unruptured intracranial aneurysms;citation_volume=34;citation_year=2013;citation_pmid=22859284;citation_doi=10.3174/ajnr.A3224" />
<meta name="citation_reference" content="citation_journal_title=J Neurosurg;citation_author=M. Piano;citation_author=L. Valvassori;citation_author=L. Quilici;citation_title=Midterm and long-term follow-up of cerebral aneurysms treated with flow diverter devices: a single-center experience;citation_pages=408-16;citation_volume=118;citation_year=2013;citation_pmid=23176329;citation_doi=10.3171/2012.10.JNS112222" />
<meta name="citation_reference" content="citation_journal_title=Radiology;citation_author=SC. Yu;citation_author=CK. Kwok;citation_author=PW. Cheng;citation_title=Intracranial aneurysms: midterm outcome of Pipeline embolization device: a prospective study in 143 patients with 178 aneurysms;citation_volume=265;citation_year=2012;citation_pmid=22996749;citation_doi=10.1148/radiol.12120422" />
<meta name="citation_reference" content="citation_journal_title=J Neurointerv Surg;citation_author=T. Hampton;citation_author=D. Walsh;citation_author=C. Tolias;citation_title=Mural destabilization after aneurysm treatment with a flow-diverting device: a report of two cases;citation_volume=3;citation_year=2011;citation_pmid=21990812;citation_doi=10.1136/jnis.2010.002873" />
<meta name="citation_reference" content="citation_journal_title=J Neurointerv Surg;citation_author=GJ. Velat;citation_author=KM. Fargen;citation_author=MF. Lawson;citation_title=Delayed intraparenchymal hemorrhage following Pipeline embolization device treatment for a giant recanalized ophthalmic aneurysm;citation_volume=4;citation_year=2012;citation_pmid=21990545;citation_doi=10.1136/neurintsurg-2011-010129" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=Z. Kulcsar;citation_author=E. Houdart;citation_author=A. Bonafe;citation_title=Intra-aneurysmal thrombosis as a possible cause of delayed aneurysm rupture after flow-diversion treatment;citation_volume=32;citation_year=2011;citation_pmid=21071538;citation_doi=10.3174/ajnr.A2370" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_journal_abbrev=Stroke;citation_author=M. Shojima;citation_author=M. Oshima;citation_author=K. Takagi;citation_title=Magnitude and Role of Wall Shear Stress on Cerebral Aneurysm: Computational Fluid Dynamic Study of 20 Middle Cerebral Artery Aneurysms;citation_pages=2500-2505;citation_volume=35;citation_year=2004;citation_issue=11;citation_issn=0039-2499;citation_pmid=15514200;citation_doi=10.1161/01.STR.0000144648.89172.0f" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=Y. Miura;citation_author=F. Ishida;citation_author=Y. Umeda;citation_title=Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms;citation_volume=44;citation_year=2013;citation_pmid=23223503;citation_doi=10.1161/STROKEAHA.112.675306" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=H. Meng;citation_author=Z. Wang;citation_author=Y. Hoi;citation_title=Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation;citation_volume=38;citation_year=2007;citation_pmid=17495215;citation_doi=10.1161/STROKEAHA.106.481234" />
<meta name="citation_reference" content="citation_journal_title=Journal of neurosurgery;citation_journal_abbrev=J Neurosurg;citation_author=C. Li;citation_author=S. Wang;citation_author=J. Chen;citation_title=Influence of hemodynamics on recanalization of totally occluded intracranial aneurysms: a patient-specific computational fluid dynamic simulation study.;citation_pages=276-283;citation_volume=117;citation_year=2012;citation_issue=2;citation_pmid=22680247;citation_doi=10.3171/2012.5.JNS111558" />
<meta name="citation_reference" content="citation_journal_title=Acta neurochirurgica;citation_journal_abbrev=Acta Neurochir (Wien);citation_author=Z. Kulcsar;citation_author=L. Augsburger;citation_author=P. Reymond;citation_title=Flow diversion treatment: intra-aneurismal blood flow velocity and WSS reduction are parameters to predict aneurysm thrombosis.;citation_pages=1827-1834;citation_volume=154;citation_year=2012;citation_issue=10;citation_pmid=22926629;citation_doi=10.1007/s00701-012-1482-2" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=F. Mut;citation_author=JR. Cebral;citation_title=Effects of flow-diverting device oversizing on hemodynamics alteration in cerebral aneurysms;citation_volume=33;citation_year=2012;citation_pmid=22555581;citation_doi=10.3174/ajnr.A3080" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=JR. Cebral;citation_author=F. Mut;citation_author=M. Raschi;citation_title=Aneurysm rupture following treatment with flow-diverting stents: computational hemodynamics analysis of treatment;citation_volume=32;citation_year=2011;citation_pmid=21071533;citation_doi=10.3174/ajnr.A2398" />
<meta name="citation_reference" content="citation_journal_title=Acta neurochirurgica;citation_journal_abbrev=Acta Neurochir (Wien);citation_author=T. Hassan;citation_author=YM. Ahmed;citation_author=AA. Hassan;citation_title=The adverse effects of flow-diverter stent-like devices on the flow pattern of saccular intracranial aneurysm models: computational fluid dynamics study.;citation_pages=1633-1640;citation_volume=153;citation_year=2011;citation_issue=8;citation_pmid=21647821;citation_doi=10.1007/s00701-011-1055-9" />
<meta name="citation_reference" content="citation_journal_title=Journal of neurosurgery;citation_journal_abbrev=J Neurosurg;citation_author=P. Venugopal;citation_author=D. Valentino;citation_author=H. Schmitt;citation_title=Sensitivity of patient-specific numerical simulation of cerebal aneurysm hemodynamics to inflow boundary conditions.;citation_pages=1051-1060;citation_volume=106;citation_year=2007;citation_issue=6;citation_pmid=17564178;citation_doi=10.3171/jns.2007.106.6.1051" />
<meta name="citation_reference" content="citation_journal_title=Annals of biomedical engineering;citation_journal_abbrev=Ann Biomed Eng;citation_author=A. Marzo;citation_author=P. Singh;citation_author=I. Larrabide;citation_title=Computational hemodynamics in cerebral aneurysms: the effects of modeled versus measured boundary conditions.;citation_pages=884-896;citation_volume=39;citation_year=2011;citation_issue=2;citation_pmid=20972626;citation_doi=10.1007/s10439-010-0187-z" />
<meta name="citation_reference" content="citation_journal_abbrev=World Neurosurg;citation_author=MR. Levitt;citation_author=DL. Cooke;citation_author=BV. Ghodke;citation_title=&quot;Stent view&quot; flat-detector CT and stent-assisted treatment strategies for complex intracranial aneurysms.;citation_pages=275-278;citation_volume=75;citation_year=2011;citation_issue=2;citation_pmid=21492730;citation_doi=10.1016/j.wneu.2010.07.042" />
<meta name="citation_reference" content="citation_journal_title=Cardiology clinics;citation_journal_abbrev=Cardiol Clin;citation_author=RG. Bach;citation_author=MJ. Kern;citation_title=Practical coronary physiology. Clinical application of the Doppler flow velocity guide wire.;citation_pages=77-99;citation_volume=15;citation_year=1997;citation_issue=1;citation_pmid=9085754;citation_doi=10.1016/S0733-8651(05)70320-9" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=SP. Ferns;citation_author=JJ. Schneiders;citation_author=M. Siebes;citation_title=Intracranial blood-flow velocity and pressure measurements using an intra-arterial dual-sensor guidewire;citation_volume=31;citation_year=2010;citation_pmid=19762460;citation_doi=10.3174/ajnr.A1718" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=JJ. Schneiders;citation_author=SP. Ferns;citation_author=P. van Ooij;citation_title=Comparison of phase-contrast MR imaging and endovascular sonography for intracranial blood flow velocity measurements;citation_volume=33;citation_year=2012;citation_pmid=22576898;citation_doi=10.3174/ajnr.A3142" />
<meta name="citation_reference" content="citation_journal_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_author=JC. Chaloupka;citation_author=F. Viñuela;citation_author=C. Kimme-Smith;citation_title=Use of a Doppler guide wire for intravascular blood flow measurements: a validation study for potential neurologic endovascular applications.;citation_pages=509-517;citation_volume=15;citation_year=1994;citation_issue=3;citation_issn=0195-6108;citation_pmid=8197948" />
<meta name="citation_reference" content="citation_journal_title=Annals of biomedical engineering;citation_journal_abbrev=Ann Biomed Eng;citation_author=L. Augsburger;citation_author=P. Reymond;citation_author=DA. Rufenacht;citation_title=Intracranial stents being modeled as a porous medium: flow simulation in stented cerebral aneurysms.;citation_pages=850-863;citation_volume=39;citation_year=2011;citation_issue=2;citation_pmid=21042856;citation_doi=10.1007/s10439-010-0200-6" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=I. Larrabide;citation_author=ML. Aguilar;citation_author=HG. Morales;citation_title=Intra-aneurysmal pressure and flow changes induced by flow diverters: relation to aneurysm size and shape;citation_volume=34;citation_year=2013;citation_pmid=23019173;citation_doi=10.3174/ajnr.A3288" />
<meta name="citation_reference" content="citation_journal_title=J Neurointerv Surg;citation_author=Y. Shobayashi;citation_author=S. Tateshima;citation_author=R. Kakizaki;citation_title=Intra-aneurysmal hemodynamic alterations by a self-expandable intracranial stent and flow diversion stent: high intra-aneurysmal pressure remains regardless of flow velocity reduction;citation_volume=5;citation_year=2013;citation_pmid=23048176;citation_doi=10.1136/neurintsurg-2012-010488" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=JJ. Schneiders;citation_author=E. Vanbavel;citation_author=CB. Majoie;citation_title=A flow-diverting stent is not a pressure-diverting stent;citation_volume=34;citation_year=2013;citation_pmid=21852372;citation_doi=10.3174/ajnr.A2613" />
<meta name="citation_reference" content="citation_journal_title=Am J Physiol Heart Circ Physiol;citation_author=P. Reymond;citation_author=Y. Bohraus;citation_author=F. Perren;citation_title=Validation of a patient-specific one-dimensional model of the systemic arterial tree;citation_volume=301;citation_year=2011;citation_pmid=21622820;citation_doi=10.1152/ajpheart.00821.2010" />
<meta name="citation_reference" content="citation_journal_title=Physiological measurement;citation_journal_abbrev=Physiol Meas;citation_author=MD. Ford;citation_author=N. Alperin;citation_author=SH. Lee;citation_title=Characterization of volumetric flow rate waveforms in the normal internal carotid and vertebral arteries.;citation_pages=477-488;citation_volume=26;citation_year=2005;citation_issue=4;citation_pmid=15886442;citation_doi=10.1088/0967-3334/26/4/013" />
<meta name="citation_reference" content="citation_journal_title=Acta neurochirurgica;citation_journal_abbrev=Acta Neurochir (Wien);citation_author=C. Karmonik;citation_author=C. Yen;citation_author=RG. Grossman;citation_title=Intra-aneurysmal flow patterns and wall shear stresses calculated with computational flow dynamics in an anterior communicating artery aneurysm depend on knowledge of patient-specific inflow rates.;citation_pages=479-485;citation_volume=151;citation_year=2009;citation_issue=5;citation_pmid=19343271;citation_doi=10.1007/s00701-009-0247-z" />
<meta name="citation_reference" content="citation_journal_title=Acta neurochirurgica;citation_journal_abbrev=Acta Neurochir (Wien);citation_author=C. Karmonik;citation_author=C. Yen;citation_author=O. Diaz;citation_title=Temporal variations of wall shear stress parameters in intracranial aneurysms--importance of patient-specific inflow waveforms for CFD calculations.;citation_pages=1391-1398;citation_volume=152;citation_year=2010;citation_issue=8;citation_pmid=20390310;citation_doi=10.1007/s00701-010-0647-0" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_journal_abbrev=Stroke;citation_author=E. Melamed;citation_author=S. Lavy;citation_author=S. Bentin;citation_title=Reduction in regional cerebral blood flow during normal aging in man;citation_pages=31-35;citation_volume=11;citation_year=1980;citation_issue=1;citation_issn=0039-2499;citation_pmid=7355426;citation_doi=10.1161/01.STR.11.1.31" />
<meta name="citation_reference" content="citation_journal_title=Physiological measurement;citation_journal_abbrev=Physiol Meas;citation_author=Y. Hoi;citation_author=BA. Wasserman;citation_author=YJ. Xie;citation_title=Characterization of volumetric flow rate waveforms at the carotid bifurcations of older adults.;citation_pages=291-302;citation_volume=31;citation_year=2010;citation_issue=3;citation_pmid=20086276;citation_doi=10.1088/0967-3334/31/3/002" />
<meta name="citation_reference" content="citation_journal_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_author=T. Hassan;citation_author=M. Ezura;citation_author=EV. Timofeev;citation_title=Computational Simulation of Therapeutic Parent Artery Occlusion to Treat Giant Vertebrobasilar Aneurysm;citation_pages=63-68;citation_volume=25;citation_year=2004;citation_issue=1;citation_issn=0195-6108;citation_pmid=14729530" />
<meta name="citation_reference" content="citation_journal_title=Medical physics;citation_journal_abbrev=Med Phys;citation_author=Q. Sun;citation_author=A. Groth;citation_author=T. Aach;citation_title=Comprehensive validation of computational fluid dynamics simulations of in-vivo blood flow in patient-specific cerebral aneurysms.;citation_pages=742-754;citation_volume=39;citation_year=2012;citation_issue=2;citation_pmid=22320784;citation_doi=10.1118/1.3675402" />
<meta name="citation_reference" content="citation_journal_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_author=LD. Jou;citation_author=CM. Quick;citation_author=WL. Young;citation_title=Computational Approach to Quantifying Hemodynamic Forces in Giant Cerebral Aneurysms;citation_pages=1804-1810;citation_volume=24;citation_year=2003;citation_issue=9;citation_issn=0195-6108;citation_pmid=14561606" />
<meta name="citation_reference" content="citation_journal_title=Magnetic resonance in medicine :  official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine;citation_journal_abbrev=Magn Reson Med;citation_author=L. Boussel;citation_author=V. Rayz;citation_author=A. Martin;citation_title=Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics.;citation_pages=409-417;citation_volume=61;citation_year=2009;citation_issue=2;citation_pmid=19161132;citation_doi=10.1002/mrm.21861" />
<meta name="citation_reference" content="citation_journal_title=J Biomech Eng;citation_title=Numerical simulations of flow in cerebral aneurysms: comparison of CFD results and in vivo MRI measurements;citation_author=VL. Rayz;citation_author=L. Boussel;citation_author=G. Acevedo-Bolton;citation_volume=130;citation_year=2008" />
<meta name="citation_reference" content="citation_journal_title=Neurosurgery;citation_journal_abbrev=Neurosurgery;citation_author=GE. Sviri;citation_author=B. Ghodke;citation_author=GW. Britz;citation_title=Transcranial Doppler grading criteria for basilar artery vasospasm.;citation_pages=360-366;citation_volume=59;citation_year=2006;citation_issue=2;citation_pmid=16883176;citation_doi=10.1227/01.NEU.0000223502.93013.6E" />
<meta name="citation_reference" content="citation_journal_title=Neurosurgery;citation_journal_abbrev=Neurosurgery;citation_author=CL. Turner;citation_author=JN. Higgins;citation_author=PJ. Kirkpatrick;citation_title=Assessment of transcranial color-coded duplex sonography for the surveillance of intracranial aneurysms treated with Guglielmi detachable coils.;citation_pages=866-871;citation_volume=53;citation_year=2003;citation_issue=4;citation_pmid=14519218;citation_doi=10.1227/01.NEU.0000083028.83235.A5" />
<meta name="citation_reference" content="citation_journal_title=Journal of vascular surgery :  official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter;citation_journal_abbrev=J Vasc Surg;citation_author=RG. Ackerstaff;citation_author=MJ. Suttorp;citation_author=JC. van den Berg;citation_title=Prediction of early cerebral outcome by transcranial Doppler monitoring in carotid bifurcation angioplasty and stenting.;citation_pages=618-624;citation_volume=41;citation_year=2005;citation_issue=4;citation_pmid=15874925;citation_doi=10.1016/j.jvs.2005.01.034" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=W. Chang;citation_author=B. Landgraf;citation_author=KM. Johnson;citation_title=Velocity measurements in the middle cerebral arteries of healthy volunteers using 3D radial phase-contrast HYPRFlow: comparison with transcranial Doppler sonography and 2D phase-contrast MR imaging;citation_volume=32;citation_year=2011;citation_pmid=20947642;citation_doi=10.3174/ajnr.A2240" />
<meta name="citation_reference" content="citation_journal_abbrev=J Eng Math;citation_author=JR. Cebral;citation_author=CM. Putman;citation_author=MT. Alley;citation_title=Hemodynamics in Normal Cerebral Arteries: Qualitative Comparison of 4D Phase-Contrast Magnetic Resonance and Image-Based Computational Fluid Dynamics.;citation_pages=367-378;citation_volume=64;citation_year=2009;citation_issue=4;citation_pmid=19684874;citation_doi=10.1007/s10665-009-9266-2" />
<meta name="citation_reference" content="citation_journal_title=Critical care (London, England);citation_journal_abbrev=Crit Care;citation_author=C. Waydhas;citation_title=Intrahospital transport of critically ill patients.;citation_pages=R83-R89;citation_volume=3;citation_year=1999;citation_issue=5;citation_pmid=11094486;citation_doi=10.1186/cc362" />
<meta name="citation_reference" content="citation_journal_title=Atherosclerosis;citation_author=JP. Mynard;citation_author=BA. Wasserman;citation_author=DA. Steinman;citation_title=Errors in the estimation of wall shear stress by maximum Doppler velocity;citation_pages=259-66;citation_volume=227;citation_year=2013;citation_pmid=23398945;citation_doi=10.1016/j.atherosclerosis.2013.01.026" />
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<meta name="twitter:title" content="Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Computational fluid dynamics modeling is useful in the study of the hemodynamic environment of cerebral aneurysms, but patient-specific measurements of boundary conditions, such as blood flow velocity and pressure, have not been previously applied to the study of flow-diverting stents. We integrated patient-specific intravascular blood flow velocity and pressure measurements into computational models of aneurysms before and after treatment with flow-diverting stents to determine stent effects on aneurysm hemodynamics.

MATERIALS AND METHODS: Blood flow velocity and pressure were measured in peri-aneurysmal locations by use of an intravascular dual-sensor pressure and Doppler velocity guidewire before and after flow-diverting stent treatment of 4 unruptured cerebral aneurysms. These measurements defined inflow and outflow boundary conditions for computational models. Intra-aneurysmal flow rates, wall shear stress, and wall shear stress gradient were calculated.

RESULTS: Measurements of inflow velocity and outflow pressure were successful in all 4 patients. Computational models incorporating these measurements demonstrated significant reductions in intra-aneurysmal wall shear stress and wall shear stress gradient and a trend in reduced intra-aneurysmal blood flow.

CONCLUSIONS: Integration of intravascular dual-sensor guidewire measurements of blood flow velocity and blood pressure provided patient-specific computational models of cerebral aneurysms. Aneurysm treatment with flow-diverting stents reduces blood flow and hemodynamic shear stress in the aneurysm dome.

CFD
:   computational fluid dynamics
WSS
:   wall shear stress
WSSG
:   wall shear stress gradient
TCD
:   transcranial Doppler ultrasonography
pcMRA
:   phase-contrast MRA" />
<meta name="og-title" property="og:title" content="Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/35/1/143" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Computational fluid dynamics modeling is useful in the study of the hemodynamic environment of cerebral aneurysms, but patient-specific measurements of boundary conditions, such as blood flow velocity and pressure, have not been previously applied to the study of flow-diverting stents. We integrated patient-specific intravascular blood flow velocity and pressure measurements into computational models of aneurysms before and after treatment with flow-diverting stents to determine stent effects on aneurysm hemodynamics.

MATERIALS AND METHODS: Blood flow velocity and pressure were measured in peri-aneurysmal locations by use of an intravascular dual-sensor pressure and Doppler velocity guidewire before and after flow-diverting stent treatment of 4 unruptured cerebral aneurysms. These measurements defined inflow and outflow boundary conditions for computational models. Intra-aneurysmal flow rates, wall shear stress, and wall shear stress gradient were calculated.

RESULTS: Measurements of inflow velocity and outflow pressure were successful in all 4 patients. Computational models incorporating these measurements demonstrated significant reductions in intra-aneurysmal wall shear stress and wall shear stress gradient and a trend in reduced intra-aneurysmal blood flow.

CONCLUSIONS: Integration of intravascular dual-sensor guidewire measurements of blood flow velocity and blood pressure provided patient-specific computational models of cerebral aneurysms. Aneurysm treatment with flow-diverting stents reduces blood flow and hemodynamic shear stress in the aneurysm dome.

CFD
:   computational fluid dynamics
WSS
:   wall shear stress
WSSG
:   wall shear stress gradient
TCD
:   transcranial Doppler ultrasonography
pcMRA
:   phase-contrast MRA" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node12753--5" data-node-nid="12753" id="top-node-12753--6788702413" data-pisa="ajnr;35/1/143" data-pisa-master="ajnr;ajnr.A3624" data-apath="/ajnr/35/1/143.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Interventional</span></span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">M.R. Levitt</span>, <span class="highwire-citation-author" data-delta="1">P.M. McGah</span>, <span class="highwire-citation-author" data-delta="2">A. Aliseda</span>, <span class="highwire-citation-author" data-delta="3">P.D. Mourad</span>, <span class="highwire-citation-author" data-delta="4">J.D. Nerva</span>, <span class="highwire-citation-author" data-delta="5">S.S. Vaidya</span>, <span class="highwire-citation-author" data-delta="6">R.P. Morton</span>, <span class="highwire-citation-author" data-delta="7">B.V. Ghodke</span> and <span class="highwire-citation-author" data-delta="8">L.J. Kim</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">January 2014,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">35 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">143-148; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A3624 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-12753--6788702413" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">M.R. Levitt </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neurological Surgery (M.R.L., P.D.M., J.D.N., R.P.M., B.V.G., L.J.K.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.R.%2BLevitt%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Levitt%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM.R.%2BLevitt%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">P.M. McGah </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Mechanical Engineering (P.M.M., A.A.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=P.M.%2BMcGah%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=McGah%20P&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AP.M.%2BMcGah%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">A. Aliseda </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Mechanical Engineering (P.M.M., A.A.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BAliseda%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Aliseda%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BAliseda%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">P.D. Mourad </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neurological Surgery (M.R.L., P.D.M., J.D.N., R.P.M., B.V.G., L.J.K.)</div><div class='author-affiliation'><span class='nlm-sup'>c</span>Applied Physics Laboratory (P.D.M.)</div><div class='author-affiliation'><span class='nlm-sup'>d</span>Bioengineering (P.D.M.)</div><div class='author-affiliation'><span class='nlm-sup'>e</span>Radiology (P.D.M., S.S.V., B.V.G., L.J.K.), University of Washington, Seattle.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=P.D.%2BMourad%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mourad%20P&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AP.D.%2BMourad%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">J.D. Nerva </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neurological Surgery (M.R.L., P.D.M., J.D.N., R.P.M., B.V.G., L.J.K.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.D.%2BNerva%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Nerva%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AJ.D.%2BNerva%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">S.S. Vaidya </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>e</span>Radiology (P.D.M., S.S.V., B.V.G., L.J.K.), University of Washington, Seattle.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.S.%2BVaidya%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Vaidya%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AS.S.%2BVaidya%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">R.P. Morton </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neurological Surgery (M.R.L., P.D.M., J.D.N., R.P.M., B.V.G., L.J.K.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.P.%2BMorton%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Morton%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AR.P.%2BMorton%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">B.V. 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 35</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 1 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jan 2014 </div></div>
      
      
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      <div class="highwire-cite-title">Cerebral Aneurysms Treated with Flow-Diverting Stents: Computational Models with Intravascular Blood Flow Measurements</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">M.R.</span> <span class="nlm-surname">Levitt</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">P.M.</span> <span class="nlm-surname">McGah</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Aliseda</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">P.D.</span> <span class="nlm-surname">Mourad</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.D.</span> <span class="nlm-surname">Nerva</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">S.S.</span> <span class="nlm-surname">Vaidya</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">R.P.</span> <span class="nlm-surname">Morton</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">B.V.</span> <span class="nlm-surname">Ghodke</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">L.J.</span> <span class="nlm-surname">Kim</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2014, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">35 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">143-148; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A3624 </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">M.R.</span> <span class="nlm-surname">Levitt</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">P.M.</span> <span class="nlm-surname">McGah</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Aliseda</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">P.D.</span> <span class="nlm-surname">Mourad</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.D.</span> <span class="nlm-surname">Nerva</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">S.S.</span> <span class="nlm-surname">Vaidya</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">R.P.</span> <span class="nlm-surname">Morton</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">B.V.</span> <span class="nlm-surname">Ghodke</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">L.J.</span> <span class="nlm-surname">Kim</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2014, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">35 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">143-148; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A3624 </span></div>
  
  
  
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