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    Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage: Proposal of an Evidence-Based Combined Clinical and Imaging Reference Standard | American Journal of Neuroradiology  
    



















    































    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage: Proposal of an Evidence-Based Combined Clinical and Imaging Reference Standard
  
    	
P.C. Sanelli, S. Kishore, A. Gupta, H. Mangat, A. Rosengart, H. Kamel and A. Segal

  
    	
American Journal of Neuroradiology December 2014,  35 (12) 2209-2214; DOI: https://doi.org/10.3174/ajnr.A3782 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. 1.↵


    1. 

    2. Hop  JW, 
    3. Rinkel  GJ, 
    4. Algra  A, et al
    . Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke 1997;28:660–64
    Abstract/FREE Full Text
  2. 2.↵


    1. 

    2. Stegmayr  B, 
    3. Eriksson  M, 
    4. Asplund  K
    . Declining mortality from subarachnoid hemorrhage: changes in incidence and case fatality from 1985 through 2000. Stroke 2004;35:2059–63
    Abstract/FREE Full Text
  3. 3.↵


    1. 

    2. Diringer  MN, 
    3. Bleck  TP, 
    4. Claude Hemphill  J  3rd., et al
    . Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care 2011;15:211–40
    CrossRefPubMedWeb of Science
  4. 4.↵


    1. 

    2. Roos  YB, 
    3. de Haan  RJ, 
    4. Beenen  LF, et al
    . Complications and outcome in patients with aneurysmal subarachnoid haemorrhage: a prospective hospital based cohort study in the Netherlands. J Neurol Neurosurg Psychiatry 2000;68:337–41
    Abstract/FREE Full Text
  5. 5.↵


    1. 

    2. Hijdra  A, 
    3. Van Gijn  J, 
    4. Stefanko  S, et al
    . Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: clinicoanatomic correlations. Neurology 1986;36:329–33
    CrossRef
  6. 6.↵


    1. 

    2. Vergouwen  MD
    , and Participants in the International Multi-Disciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage. Vasospasm versus delayed cerebral ischemia as an outcome event in clinical trials and observational studies. Neurocrit Care 2011;15:308–11
    CrossRefPubMed
  7. 7.↵


    1. 

    2. van der Schaaf  IC, 
    3. Ruigrok  YM, 
    4. Rinkel  GJ, et al
    . Study design and outcome measures in studies on aneurysmal subarachnoid hemorrhage. Stroke 2002;33:2043–46
    Abstract/FREE Full Text
  8. 8.↵


    1. 

    2. Reichman  M, 
    3. Gold  R, 
    4. Greenberg  E, et al
    . Validation of a new reference standard for the diagnosis of vasospasm. Acad Radiol 2010;17:1083–89
    CrossRefPubMed
  9. 9.↵


    1. 

    2. Sanelli  PC, 
    3. Anumula  N, 
    4. Gold  R, et al
    . Outcomes-based assessment of a new reference standard for delayed cerebral ischemia related to vasospasm in aneurysmal subarachnoid hemorrhage. Acad Radiol 2012;19:1066–74
    CrossRefPubMed
  10. 10.↵


    1. 

    2. Vergouwen  MD, 
    3. Vermeulen  M, 
    4. van Gijn  J, et al
    . Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke 2010;41:2391–95
    Abstract/FREE Full Text
  11. 11.↵


    1. 

    2. Vergouwen  MD, 
    3. Ilodigwe  D, 
    4. Macdonald  RL
    . Cerebral infarction after subarachnoid hemorrhage contributes to poor outcome by vasospasm-dependent and -independent effects. Stroke 2011;42:924–29
    Abstract/FREE Full Text
  12. 12.↵


    1. 

    2. Dankbaar  JW, 
    3. Rijsdijk  M, 
    4. van der Schaaf  IC, et al
    . Relationship between vasospasm, cerebral perfusion, and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Neuroradiology 2009;51:813–19
    CrossRefPubMedWeb of Science
  13. 13.↵


    1. 

    2. Etminan  N, 
    3. Vergouwen  MD, 
    4. Ilodigwe  D, et al
    . Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis. J Cereb Blood Flow Metab 2011;31:1443–51
    CrossRefPubMed
  14. 14.↵


    Centre For Evidence Based Medicine. OCEBM Levels of Evidence Working Group. Oxford levels of evidence 1. http://www.cebm.net/index.aspx?o=5653. Accessed March 29, 2013. 
  15. 15.↵


    1. 

    2. Kreiter  KT, 
    3. Mayer  SA, 
    4. Howard  G, et al
    . Sample size estimates for clinical trials of vasospasm in subarachnoid hemorrhage. Stroke 2009;40:2362–67
    Abstract/FREE Full Text
  16. 16.↵


    1. 

    2. Frontera  JA, 
    3. Fernandez  A, 
    4. Schmidt  JM, et al
    . Defining vasospasm after subarachnoid hemorrhage: what is the most clinically relevant definition? Stroke 2009;40:1963–68
    Abstract/FREE Full Text
  17. 17.↵


    1. 

    2. Vergouwen  MD, 
    3. Etminan  N, 
    4. Ilodigwe  D, et al
    . Lower incidence of cerebral infarction correlates with improved functional outcome after aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab 2011;31:1545–53
    CrossRefPubMed
  18. 18.↵


    1. 

    2. Pickard  JD, 
    3. Murray  GD, 
    4. Illingworth  R, et al
    . Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. BMJ 1989;298:636–42
    Abstract/FREE Full Text
  19. 19.↵


    1. 

    2. Etminan  N, 
    3. Vergouwen  MD, 
    4. Macdonald  RL
    . Angiographic vasospasm versus cerebral infarction as outcome measures after aneurysmal subarachnoid hemorrhage. Acta Neurochir Suppl 2013;115:33–40
    PubMed
  20. 20.↵


    1. 

    2. Fisher  CM, 
    3. Roberson  GH, 
    4. Ojemann  RG
    . Cerebral vasospasm with ruptured saccular aneurysm–the clinical manifestations. Neurosurgery 1977;1:245–48
    CrossRefPubMed
  21. 21.↵


    1. 

    2. Rabinstein  AA, 
    3. Friedman  JA, 
    4. Weigand  SD, et al
    . Predictors of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke 2004;35:1862–66
    Abstract/FREE Full Text
  22. 22.↵


    1. 

    2. Fergusen  S, 
    3. Macdonald  RL
    . Predictors of cerebral infarction in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2007;60:658–67, discussion 667
    PubMedWeb of Science
  23. 23.↵


    1. 

    2. Crowley  RW, 
    3. Medel  R, 
    4. Dumont  AS, et al
    . Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage. Stroke 2011;42:919–23
    Abstract/FREE Full Text
  24. 24.↵


    1. 

    2. Wintermark  M, 
    3. Ko  NU, 
    4. Smith  WS, et al
    . Vasospasm after subarachnoid hemorrhage: utility of perfusion CT and CT angiography on diagnosis and management. AJNR Am J Neuroradiol 2006;27:26–34
    Abstract/FREE Full Text
  25. 25.↵


    1. 

    2. Washington  CW, 
    3. Zipfel  GJ
    , and Participants in the International Multi-Disciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage. Detection and monitoring of vasospasm and delayed cerebral ischemia: a review and assessment of the literature. Neurocrit Care 2011;15:312–17
    CrossRefPubMedWeb of Science
  26. 26.↵


    1. 

    2. Schmidt  JM, 
    3. Wartenberg  KE, 
    4. Fernandez  A, et al
    . Frequency and clinical impact of asymptomatic cerebral infarction due to vasospasm after subarachnoid hemorrhage. J Neurosurg 2008;109:1052–59
    CrossRefPubMedWeb of Science
  27. 27.↵


    1. 

    2. Unterberg  AW, 
    3. Sakowitz  OW, 
    4. Sarrafzadeh  AS, et al
    . Role of bedside microdialysis in the diagnosis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 2001;94:740–49
    CrossRefPubMedWeb of Science
  28. 28.↵


    1. 

    2. Wagner  M, 
    3. Steinbeis  P, 
    4. Guresir  E, et al
    . Beyond delayed cerebral vasospasm: infarct patterns in patients with subarachnoid hemorrhage. Clin Neuroradiol 2013;23:87–95
    CrossRefPubMed
  29. 29.↵


    1. 

    2. Sanelli  PC, 
    3. Anumula  N, 
    4. Johnson  CE, et al
    . Evaluating CT perfusion using outcome measures of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage. AJNR Am J Neuroradiol 2013;34:292–98
    Abstract/FREE Full Text
  30. 30.↵


    1. 

    2. Dankbaar  JW, 
    3. de Rooij  NK, 
    4. Velthuis  BK, et al
    . Diagnosing delayed cerebral ischemia with different CT modalities in patients with subarachnoid hemorrhage with clinical deterioration. Stroke 2009;40:3493–98
    Abstract/FREE Full Text
  31. 31.↵


    1. 

    2. Greenberg  ED, 
    3. Gold  R, 
    4. Reichman  M, et al
    . Diagnostic accuracy of CT angiography and CT perfusion for cerebral vasospasm: a meta-analysis. AJNR Am J Neuroradiol 2010;31:1853–60
    Abstract/FREE Full Text
  32. 32.↵


    1. 

    2. Wintermark  M, 
    3. Reichhart  M, 
    4. Cuisenaire  O, et al
    . Comparison of admission perfusion computed tomography and qualitative diffusion- and perfusion-weighted magnetic resonance imaging in acute stroke patients. Stroke 2002;33:2025–31
    Abstract/FREE Full Text
  33. 33.↵


    1. 

    2. Schramm  P, 
    3. Schellinger  PD, 
    4. Klotz  E, et al
    . Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration. Stroke 2004;35:1652–58
    Abstract/FREE Full Text
  34. 34.↵


    1. 

    2. Chieregato  A, 
    3. Tanfani  A, 
    4. Noto  A, et al
    . Cerebral blood flow thresholds predicting new hypoattenuation areas due to macrovascular ischemia during the acute phase of severe and complicated aneurysmal subarachnoid hemorrhage: a preliminary study. Acta Neurochir Suppl 2008;102:311–16
    CrossRefPubMed
  35. 35.↵


    1. 

    2. Peerdeman  SM, 
    3. van Tulder  MW, 
    4. Vandertop  WP
    . Cerebral microdialysis as a monitoring method in subarachnoid hemorrhage patients, and correlation with clinical events–a systematic review. J Neurol 2003;250:797–805
    CrossRefPubMedWeb of Science
  36. 36.↵


    1. 

    2. Sarrafzadeh  A, 
    3. Haux  D, 
    4. Sakowitz  O, et al
    . Acute focal neurological deficits in aneurysmal subarachnoid hemorrhage: relation of clinical course, CT findings, and metabolite abnormalities monitored with bedside microdialysis. Stroke 2003;34:1382–88
    Abstract/FREE Full Text
  37. 37.↵


    1. 

    2. Cerejo  A, 
    3. Silva  PA, 
    4. Vilarinho  A, et al
    . Intraoperative brain oxygenation monitoring and vasospasm in aneurysmal subarachnoid hemorrhage. Neurol Res 2012;34:181–86
    PubMed
  38. 38.↵


    1. 

    2. Yokose  N, 
    3. Sakatani  K, 
    4. Murata  Y, et al
    . Bedside assessment of cerebral vasospasms after subarachnoid hemorrhage by near infrared time-resolved spectroscopy. Adv Exp Med Biol 2010;662:505–11
    CrossRefPubMed
  39. 39.↵


    1. 

    2. Yokose  N, 
    3. Sakatani  K, 
    4. Murata  Y, et al
    . Bedside monitoring of cerebral blood oxygenation and hemodynamics after aneurysmal subarachnoid hemorrhage by quantitative time-resolved near-infrared spectroscopy. World Neurosurg 2010;73:508–13
    CrossRefPubMedWeb of Science
  40. 40.↵


    1. 

    2. Anderson  GB, 
    3. Ashforth  R, 
    4. Steinke  DE, et al
    . CT angiography for the detection of cerebral vasospasm in patients with acute subarachnoid hemorrhage. AJNR Am J Neuroradiol 2000;21:1011–15
    Abstract/FREE Full Text
  41. 41.↵


    1. 

    2. Wintermark  M, 
    3. Dillon  WP, 
    4. Smith  WS, et al
    . Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT. Cerebrovasc Dis 2008;26:163–70
    CrossRefPubMed
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage: Proposal of an Evidence-Based Combined Clinical and Imaging Reference Standard
  
    	
P.C. Sanelli, S. Kishore, A. Gupta, H. Mangat, A. Rosengart, H. Kamel, A. Segal

  
    	
 American Journal of Neuroradiology Dec 2014, 35 (12) 2209-2214; DOI: 10.3174/ajnr.A3782 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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