Research ArticleBrain
Open Access
Pretreatment ADC Histogram Analysis Is a Predictive Imaging Biomarker for Bevacizumab Treatment but Not Chemotherapy in Recurrent Glioblastoma
B.M. Ellingson, S. Sahebjam, H.J. Kim, W.B. Pope, R.J. Harris, D.C. Woodworth, A. Lai, P.L. Nghiemphu, W.P. Mason and T.F. Cloughesy
American Journal of Neuroradiology April 2014, 35 (4) 673-679; DOI: https://doi.org/10.3174/ajnr.A3748
B.M. Ellingson
aFrom the Departments of Radiological Sciences (B.M.E., H.J.K., W.B.P., R.J.H., D.C.W.)
bBiomedical Physics (B.M.E., R.J.H., D.C.W.)
cBioengineering (B.M.E.)
S. Sahebjam
eDepartment of Medicine (S.S., W.P.M.), Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.
H.J. Kim
aFrom the Departments of Radiological Sciences (B.M.E., H.J.K., W.B.P., R.J.H., D.C.W.)
W.B. Pope
aFrom the Departments of Radiological Sciences (B.M.E., H.J.K., W.B.P., R.J.H., D.C.W.)
R.J. Harris
aFrom the Departments of Radiological Sciences (B.M.E., H.J.K., W.B.P., R.J.H., D.C.W.)
bBiomedical Physics (B.M.E., R.J.H., D.C.W.)
D.C. Woodworth
aFrom the Departments of Radiological Sciences (B.M.E., H.J.K., W.B.P., R.J.H., D.C.W.)
bBiomedical Physics (B.M.E., R.J.H., D.C.W.)
A. Lai
dNeurology (A.L., P.L.N., T.F.C.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California
P.L. Nghiemphu
dNeurology (A.L., P.L.N., T.F.C.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California
W.P. Mason
eDepartment of Medicine (S.S., W.P.M.), Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.
T.F. Cloughesy
dNeurology (A.L., P.L.N., T.F.C.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California

References
- 1.↵
Central Brain Tumor Registry of the United States. CBTRUS Statistical Report Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004–2006. http://www.cbtrus.org/2010-NPCR-SEER/CBTRUS-WEBREPORT-Final-3-2-10.pdf. Accessed January 2013
- 2.↵
- Stupp R,
- Mason WP,
- van den Bent MJ,
- et al
- 3.↵
- Wong ET,
- Hess KR,
- Gleason MJ,
- et al
- 4.↵
- Plate KH,
- Breier G,
- Risau W
- 5.↵
- 6.↵
- Holash J,
- Maisonpierre PC,
- Compton D,
- et al
- 7.↵
- 8.↵
- 9.↵
- Pope WB,
- Kim HJ,
- Huo J,
- et al
- 10.↵
- Pope WB,
- Lai A,
- Mehta R,
- et al
- 11.↵
- Ellingson BM,
- Bedekar DP,
- Malkin MG,
- et al
- 12.↵
- Ellingson BM,
- Cloughesy TF,
- Lai A,
- et al
- 13.↵
- 14.↵
- 15.↵
- Kothari PD,
- White NS,
- Farid N,
- et al
- 16.↵
- White NS,
- McDonald CR,
- Farid N,
- et al
- 17.↵
- Andre JB,
- Lu S,
- Spearman K,
- et al
- 18.↵
- Gerstner ER,
- Frosch MP,
- Batchelor TT
- 19.↵
- 20.↵
- Pope WB,
- Mirsadraei L,
- Lai A,
- et al
- 21.↵
- Lucio-Eterovic AK,
- Piao Y,
- de Groot JF
- 22.↵
- Keunen O,
- Johansson M,
- Oudin A,
- et al
- 23.↵
- Padhani AR,
- Liu G,
- Mu-Koh D,
- et al
- 24.↵
- Gerstner ER,
- Chen PJ,
- Wen PY,
- et al
In this issue
American Journal of Neuroradiology
Vol. 35, Issue 4
1 Apr 2014
Advertisement
Pretreatment ADC Histogram Analysis Is a Predictive Imaging Biomarker for Bevacizumab Treatment but Not Chemotherapy in Recurrent Glioblastoma
B.M. Ellingson, S. Sahebjam, H.J. Kim, W.B. Pope, R.J. Harris, D.C. Woodworth, A. Lai, P.L. Nghiemphu, W.P. Mason, T.F. Cloughesy
American Journal of Neuroradiology Apr 2014, 35 (4) 673-679; DOI: 10.3174/ajnr.A3748
Pretreatment ADC Histogram Analysis Is a Predictive Imaging Biomarker for Bevacizumab Treatment but Not Chemotherapy in Recurrent Glioblastoma
B.M. Ellingson, S. Sahebjam, H.J. Kim, W.B. Pope, R.J. Harris, D.C. Woodworth, A. Lai, P.L. Nghiemphu, W.P. Mason, T.F. Cloughesy
American Journal of Neuroradiology Apr 2014, 35 (4) 673-679; DOI: 10.3174/ajnr.A3748
Jump to section
Related Articles
- No related articles found.
Cited By...
- Pretreatment ADC Histogram Analysis as a Prognostic Imaging Biomarker for Patients with Recurrent Glioblastoma Treated with Bevacizumab: A Systematic Review and Meta-analysis
- MRI and 18FET-PET Predict Survival Benefit from Bevacizumab Plus Radiotherapy in Patients with Isocitrate Dehydrogenase Wild-type Glioblastoma: Results from the Randomized ARTE Trial
- Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches
- Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials
- Restriction Spectrum Imaging Improves Risk Stratification in Patients with Glioblastoma
- Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement