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    Synthetic MRI in the Detection of Multiple Sclerosis Plaques | American Journal of Neuroradiology  
    



















    































    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Research ArticleADULT BRAIN

  
      
Open Access

  
      
Synthetic MRI in the Detection of Multiple Sclerosis Plaques
  
    	
A. Hagiwara, M. Hori, K. Yokoyama, M.Y. Takemura, C. Andica, T. Tabata, K. Kamagata, M. Suzuki, K.K. Kumamaru, M. Nakazawa, N. Takano, H. Kawasaki, N. Hamasaki, A. Kunimatsu and S. Aoki

  
    	
American Journal of Neuroradiology February 2017,  38 (2) 257-263; DOI: https://doi.org/10.3174/ajnr.A5012 

  
  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  


  
  



  
      
  
  

    

  

    

  
      
  
  

    
References
  1. 1.↵
    1. 

    2. Bonzano  L, 
    3. Roccatagliata  L, 
    4. Mancardi  GL, et al
    . Gadolinium-enhancing or active T2 magnetic resonance imaging lesions in multiple sclerosis clinical trials? Mult Scler 2009;15:1043–47 doi:10.1177/1352458509106610 pmid:19570818
    Abstract/FREE Full Text
  2. 2.↵
    1. 

    2. Lavery  AM, 
    3. Verhey  LH, 
    4. Waldman  AT
    . Outcome measures in relapsing-remitting multiple sclerosis: capturing disability and disease progression in clinical trials. Mult Scler Int 2014;2014:262350 doi:10.1155/2014/262350 pmid:24883205
    CrossRefPubMed
  3. 3.↵
    1. 

    2. Geurts  JJ, 
    3. Pouwels  PJ, 
    4. Uitdehaag  BM, et al
    . Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging. Radiology 2005;236:254–60 pmid:15987979
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. 

    2. Nelson  F, 
    3. Poonawalla  AH, 
    4. Hou  P, et al
    . Improved identification of intracortical lesions in multiple sclerosis with phase-sensitive inversion recovery in combination with fast double inversion recovery MR imaging. AJNR Am J Neuroradiol 2007;28:1645–49 pmid:17885241
    Abstract/FREE Full Text
  5. 5.↵
    1. 

    2. Wattjes  MP, 
    3. Lutterbey  GG, 
    4. Gieseke  J, et al
    . Double inversion recovery brain imaging at 3T: diagnostic value in the detection of multiple sclerosis lesions. AJNR Am J Neuroradiol 2007;28:54–59 pmid:17213424
    Abstract/FREE Full Text
  6. 6.↵
    1. 

    2. Sethi  V, 
    3. Yousry  TA, 
    4. Muhlert  N, et al
    . Improved detection of cortical MS lesions with phase-sensitive inversion recovery MRI. J Neurol Neurosurg Psychiatry 2012;83:877–82 doi:10.1136/jnnp-2012-303023 pmid:22807559
    Abstract/FREE Full Text
  7. 7.↵
    1. 

    2. Bedell  BJ, 
    3. Narayana  PA
    . Implementation and evaluation of a new pulse sequence for rapid acquisition of double inversion recovery images for simultaneous suppression of white matter and CSF. J Magn Reson Imaging 1998;8:544–47 pmid:9626866
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. 

    2. Hou  P, 
    3. Hasan  KM, 
    4. Sitton  CW, et al
    . Phase-sensitive T1 inversion recovery imaging: a time-efficient interleaved technique for improved tissue contrast in neuroimaging. AJNR Am J Neuroradiol 2005;26:1432–38 pmid:15956512
    Abstract/FREE Full Text
  9. 9.↵
    1. 

    2. Bobman  SA, 
    3. Riederer  SJ, 
    4. Lee  JN, et al
    . Cerebral magnetic resonance image synthesis. AJNR Am J Neuroradiol 1985;6:265–69 pmid:2984911
    Abstract/FREE Full Text
  10. 10.↵
    1. 

    2. Riederer  SJ, 
    3. Suddarth  SA, 
    4. Bobman  SA, et al
    . Automated MR image synthesis: feasibility studies. Radiology 1984;153:203–06 pmid:6089265
    CrossRefPubMed
  11. 11.↵
    1. 

    2. Warntjes  JB, 
    3. Leinhard  OD, 
    4. West  J, et al
    . Rapid magnetic resonance quantification on the brain: optimization for clinical usage. Magn Reson Med 2008;60:320–29 pmid:18666127
    CrossRefPubMed
  12. 12.↵
    1. 

    2. Krauss  W, 
    3. Gunnarsson  M, 
    4. Andersson  T, et al
    . Accuracy and reproducibility of a quantitative magnetic resonance imaging method for concurrent measurements of tissue relaxation times and proton density. Magn Reson Imaging 2015;33:584–91 doi:10.1016/j.mri.2015.02.013 pmid:25708264
    CrossRefPubMed
  13. 13.↵
    1. 

    2. Blystad  I, 
    3. Warntjes  JB, 
    4. Smedby  O, et al
    . Synthetic MRI of the brain in a clinical setting. Acta Radiol 2012;53:1158–63 doi:10.1258/ar.2012.120195 pmid:23024181
    Abstract/FREE Full Text
  14. 14.↵
    1. 

    2. Hagiwara  A, 
    3. Hori  M, 
    4. Suzuki  M, et al
    . Contrast-enhanced synthetic MRI for the detection of brain metastases. Acta Radiol Open 2016;5:2058460115626757 doi:1177/2058460115626757 pmid:26962461
    Abstract/FREE Full Text
  15. 15.↵
    1. 

    2. Hagiwara  A, 
    3. Nakazawa  M, 
    4. Andica  C, et al
    . Dural enhancement in a patient with Sturge-Weber syndrome revealed by double inversion recovery contrast using synthetic MRI. Magn Reson Med Sci 2016;15:151–52 doi:10.2463/mrms.ci.2015-0066 pmid:26549162
    CrossRefPubMed
  16. 16.↵
    1. 

    2. Andica  C, 
    3. Hagiwara  A, 
    4. Nakazawa  M, et al
    . The advantage of synthetic MRI for the visualization of early white matter change in an infant with Sturge-Weber syndrome. Magn Reson Med Sci 2016;15:347–48 doi:10.2463/mrms.ci.2015-0164 pmid:27001386
    CrossRefPubMed
  17. 17.↵
    1. 

    2. West  J, 
    3. Aalto  A, 
    4. Tisell  A, et al
    . Normal appearing and diffusely abnormal white matter in patients with multiple sclerosis assessed with quantitative MR. PLoS One 2014;9:e95161 doi:10.1371/journal.pone.0095161 pmid:24747946
    CrossRefPubMed
  18. 18.↵
    1. 

    2. Blystad  I, 
    3. Hakansson  I, 
    4. Tisell  A, et al
    . Quantitative MRI for analysis of active multiple sclerosis lesions without gadolinium-based contrast agent. AJNR Am J Neuroradiol 2016;37:94–100 doi:10.3174/ajnr.A4501 pmid:26471751
    Abstract/FREE Full Text
  19. 19.↵
    1. 

    2. Granberg  T, 
    3. Uppman  M, 
    4. Hashim  F, et al
    . Clinical feasibility of synthetic MRI in multiple sclerosis: a diagnostic and volumetric validation study. AJNR Am J Neuroradiol 2016;37:1023–29 doi:10.3174/ajnr.A4665 pmid:26797137
    Abstract/FREE Full Text
  20. 20.↵
    1. 

    2. McDonald  WI, 
    3. Compston  A, 
    4. Edan  G, et al
    . Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis. Ann Neurol 2001;50:121–27 pmid:11456302
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. 

    2. Polman  CH, 
    3. Reingold  SC, 
    4. Edan  G, et al
    . Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria.” Ann Neurol 2005;58:840–46 pmid:16283615
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. 

    2. Polman  CH, 
    3. Reingold  SC, 
    4. Banwell  B, et al
    . Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011;69:292–302 doi:10.1002/ana.22366 pmid:21387374
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. 

    2. Seewann  A, 
    3. Vrenken  H, 
    4. van der Valk  P, et al
    . Diffusely abnormal white matter in chronic multiple sclerosis: imaging and histopathologic analysis. Arch Neurol 2009;66:601–09 pmid:19433660
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. 

    2. Kurtzke  JF
    . A new scale for evaluating disability in multiple sclerosis. Neurology 1955;5:580–83 pmid:13244774
    FREE Full Text
  25. 25.↵
    1. 

    2. Gabr  RE, 
    3. Sun  X, 
    4. Pednekar  AS, et al
    . Automated patient-specific optimization of three-dimensional double-inversion recovery magnetic resonance imaging. Magn Reson Med 2016;75:585–93 doi:10.1002/mrm.25616 pmid:25761973
    CrossRefPubMed
  26. 26.↵
    1. 

    2. Redpath  TW, 
    3. Smith  FW
    . Technical note: use of a double inversion recovery pulse sequence to image selectively grey or white brain matter. Br J Radiol 1994;67:1258–63 pmid:7874427
    Abstract/FREE Full Text
  27. 27.↵
    1. 

    2. Traboulsee  A, 
    3. Simon  JH, 
    4. Stone  L, et al
    . Revised recommendations of the Consortium of MS Centers Task Force for a standardized MRI protocol and clinical guidelines for the diagnosis and follow-up of multiple sclerosis. AJNR Am J Neuroradiol 2016;37:394–401 doi:10.3174/ajnr.A4539 pmid:26564433
    Abstract/FREE Full Text
  28. 28.↵
    1. 

    2. Wattjes  MP, 
    3. Rovira  À, 
    4. Miller  D, et al
    ; MAGNIMS study group. Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis–establishing disease prognosis and monitoring patients. Nat Rev Neurol 2015;11:597–606 doi:10.1038/nrneurol.2015.157 pmid:26369511
    CrossRefPubMed
  


  
  



  




  


  
  



  
      
  
  

    
  


  
  



  
      
  
  

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Synthetic MRI in the Detection of Multiple Sclerosis Plaques
  
    	
A. Hagiwara, M. Hori, K. Yokoyama, M.Y. Takemura, C. Andica, T. Tabata, K. Kamagata, M. Suzuki, K.K. Kumamaru, M. Nakazawa, N. Takano, H. Kawasaki, N. Hamasaki, A. Kunimatsu, S. Aoki

  
    	
 American Journal of Neuroradiology Feb 2017, 38 (2) 257-263; DOI: 10.3174/ajnr.A5012 

  
  
  



  


  
  



  
      
  
  

    

  
    
  
  
    
  
  
    
  


  


  
  



  
      
  
  

    
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