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<!DOCTYPE html>
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<meta name="DC.Title" content="Flow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-Analysis" />
<meta name="DC.Identifier" content="10.3174/ajnr.A6352" />
<meta name="DC.Date" content="2020-01-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2020 by American Journal of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="BACKGROUND: Treatment management and outcomes of unruptured nonsaccular aneurysms are different compared with their saccular counterparts.

PURPOSE: Our aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions.

DATA SOURCES: A systematic search of 3 data bases (2005–2019) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

STUDY SELECTION: We included studies reporting flow diversion for nonsaccular unruptured aneurysms of the posterior and distal anterior circulations. Anterior circulation lesions were included if located distal to the petrocavernous and supraclinoid ICA (MCA, A1, anterior communicating artery, A2). Giant dolichoectatic holobasilar lesions were excluded because of their poor treatment outcomes.

DATA ANALYSIS: Aneurysm occlusion and complication rates were calculated (random effects meta-analysis).

DATA SYNTHESIS: We included 15 studies (213 aneurysms). The long-term adequate occlusion rate was 85.3% (137/168; 95% CI, 78.2%–92.4%; I2 = 42.3%). Treatment-related complications were 17.4% (41/213; 95% CI, 12.45%–22.4%; I2 = 0%). Overall, 15% (37/213; 95% CI, 10%–20%; I2 = 0%) were ischemic events. Procedure-related morbidity was 8% (20/213; 95% CI, 5%–12%; I2 = 0%). Fusiform or dissecting types had comparable adequate occlusion (116/146 = 83%; 95% CI, 74%–92%; I2 = 48% versus 33/36 = 89%; 95% CI, 80%–98%; I2 = 0%; P  = .31) and complication rates (35/162 = 17%; 95% CI, 10%–25%; I2 = 24% versus 11/51 = 19%; 95% CI, 10%–31%; I2 = 0%; P  = .72). Aneurysm size (&gt;10 versus ≤10 mm) was independently associated with a higher rate of complications (OR = 6.6; 95% CI, 1.3–15; P  = .02). The rate of ischemic events after discontinuation of the antiplatelet therapy was 5% (5/93; 95% CI, 2%–9%; I2 = 0%).

LIMITATIONS: Small and retrospective studies were available for this meta-analysis.

CONCLUSIONS: Unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with flow diversion. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (&gt;10 mm) significantly increases the risk of procedure-related adverse events.

AC
:   anterior circulation
FD
:   flow diversion
IQR
:   interquartile range
PC
:   posterior circulation" />
<meta name="DC.Contributor" content="F. Cagnazzo" />
<meta name="DC.Contributor" content="P.-H. Lefevre" />
<meta name="DC.Contributor" content="I. Derraz" />
<meta name="DC.Contributor" content="C. Dargazanli" />
<meta name="DC.Contributor" content="G. Gascou" />
<meta name="DC.Contributor" content="D.T. di Carlo" />
<meta name="DC.Contributor" content="P. Perrini" />
<meta name="DC.Contributor" content="R. Ahmed" />
<meta name="DC.Contributor" content="J.F. Hak" />
<meta name="DC.Contributor" content="C. Riquelme" />
<meta name="DC.Contributor" content="A. Bonafe" />
<meta name="DC.Contributor" content="V. Costalat" />
<meta name="article:published_time" content="2020-01-01" />
<meta name="article:section" content="Interventional" />
<meta name="citation_title" content="Flow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-Analysis" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND:&lt;/h3&gt;
&lt;p&gt;Treatment management and outcomes of unruptured nonsaccular aneurysms are different compared with their saccular counterparts.&lt;/p&gt;&lt;h3&gt;PURPOSE:&lt;/h3&gt;
&lt;p&gt;Our aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions.&lt;/p&gt;&lt;h3&gt;DATA SOURCES:&lt;/h3&gt;
&lt;p&gt;A systematic search of 3 data bases (2005–2019) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.&lt;/p&gt;&lt;h3&gt;STUDY SELECTION:&lt;/h3&gt;
&lt;p&gt;We included studies reporting flow diversion for nonsaccular unruptured aneurysms of the posterior and distal anterior circulations. Anterior circulation lesions were included if located distal to the petrocavernous and supraclinoid ICA (MCA, A1, anterior communicating artery, A2). Giant dolichoectatic holobasilar lesions were excluded because of their poor treatment outcomes.&lt;/p&gt;&lt;h3&gt;DATA ANALYSIS:&lt;/h3&gt;
&lt;p&gt;Aneurysm occlusion and complication rates were calculated (random effects meta-analysis).&lt;/p&gt;&lt;h3&gt;DATA SYNTHESIS:&lt;/h3&gt;
&lt;p&gt;We included 15 studies (213 aneurysms). The long-term adequate occlusion rate was 85.3% (137/168; 95% CI, 78.2%–92.4%; I&lt;sup&gt;2&lt;/sup&gt; = 42.3%). Treatment-related complications were 17.4% (41/213; 95% CI, 12.45%–22.4%; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Overall, 15% (37/213; 95% CI, 10%–20%; I&lt;sup&gt;2&lt;/sup&gt; = 0%) were ischemic events. Procedure-related morbidity was 8% (20/213; 95% CI, 5%–12%; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Fusiform or dissecting types had comparable adequate occlusion (116/146 = 83%; 95% CI, 74%–92%; I&lt;sup&gt;2&lt;/sup&gt; = 48% versus 33/36 = 89%; 95% CI, 80%–98%; I&lt;sup&gt;2&lt;/sup&gt; = 0%; &lt;i&gt;P &lt;/i&gt;= .31) and complication rates (35/162 = 17%; 95% CI, 10%–25%; I&lt;sup&gt;2&lt;/sup&gt; = 24% versus 11/51 = 19%; 95% CI, 10%–31%; I&lt;sup&gt;2&lt;/sup&gt; = 0%; &lt;i&gt;P &lt;/i&gt;= .72). Aneurysm size (&amp;gt;10 versus ≤10 mm) was independently associated with a higher rate of complications (OR = 6.6; 95% CI, 1.3–15; &lt;i&gt;P &lt;/i&gt;= .02). The rate of ischemic events after discontinuation of the antiplatelet therapy was 5% (5/93; 95% CI, 2%–9%; I&lt;sup&gt;2&lt;/sup&gt; = 0%).&lt;/p&gt;&lt;h3&gt;LIMITATIONS:&lt;/h3&gt;
&lt;p&gt;Small and retrospective studies were available for this meta-analysis.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with flow diversion. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (&amp;gt;10 mm) significantly increases the risk of procedure-related adverse events.&lt;/p&gt;" />
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<meta name="twitter:title" content="Flow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-Analysis" />
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<meta name="twitter:description" content="BACKGROUND: Treatment management and outcomes of unruptured nonsaccular aneurysms are different compared with their saccular counterparts.

PURPOSE: Our aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions.

DATA SOURCES: A systematic search of 3 data bases (2005–2019) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

STUDY SELECTION: We included studies reporting flow diversion for nonsaccular unruptured aneurysms of the posterior and distal anterior circulations. Anterior circulation lesions were included if located distal to the petrocavernous and supraclinoid ICA (MCA, A1, anterior communicating artery, A2). Giant dolichoectatic holobasilar lesions were excluded because of their poor treatment outcomes.

DATA ANALYSIS: Aneurysm occlusion and complication rates were calculated (random effects meta-analysis).

DATA SYNTHESIS: We included 15 studies (213 aneurysms). The long-term adequate occlusion rate was 85.3% (137/168; 95% CI, 78.2%–92.4%; I2 = 42.3%). Treatment-related complications were 17.4% (41/213; 95% CI, 12.45%–22.4%; I2 = 0%). Overall, 15% (37/213; 95% CI, 10%–20%; I2 = 0%) were ischemic events. Procedure-related morbidity was 8% (20/213; 95% CI, 5%–12%; I2 = 0%). Fusiform or dissecting types had comparable adequate occlusion (116/146 = 83%; 95% CI, 74%–92%; I2 = 48% versus 33/36 = 89%; 95% CI, 80%–98%; I2 = 0%; P  = .31) and complication rates (35/162 = 17%; 95% CI, 10%–25%; I2 = 24% versus 11/51 = 19%; 95% CI, 10%–31%; I2 = 0%; P  = .72). Aneurysm size (&gt;10 versus ≤10 mm) was independently associated with a higher rate of complications (OR = 6.6; 95% CI, 1.3–15; P  = .02). The rate of ischemic events after discontinuation of the antiplatelet therapy was 5% (5/93; 95% CI, 2%–9%; I2 = 0%).

LIMITATIONS: Small and retrospective studies were available for this meta-analysis.

CONCLUSIONS: Unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with flow diversion. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (&gt;10 mm) significantly increases the risk of procedure-related adverse events.

AC
:   anterior circulation
FD
:   flow diversion
IQR
:   interquartile range
PC
:   posterior circulation" />
<meta name="og-title" property="og:title" content="Flow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-Analysis" />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND: Treatment management and outcomes of unruptured nonsaccular aneurysms are different compared with their saccular counterparts.

PURPOSE: Our aim was to analyze the outcomes after flow diversion among nonsaccular unruptured lesions.

DATA SOURCES: A systematic search of 3 data bases (2005–2019) was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

STUDY SELECTION: We included studies reporting flow diversion for nonsaccular unruptured aneurysms of the posterior and distal anterior circulations. Anterior circulation lesions were included if located distal to the petrocavernous and supraclinoid ICA (MCA, A1, anterior communicating artery, A2). Giant dolichoectatic holobasilar lesions were excluded because of their poor treatment outcomes.

DATA ANALYSIS: Aneurysm occlusion and complication rates were calculated (random effects meta-analysis).

DATA SYNTHESIS: We included 15 studies (213 aneurysms). The long-term adequate occlusion rate was 85.3% (137/168; 95% CI, 78.2%–92.4%; I2 = 42.3%). Treatment-related complications were 17.4% (41/213; 95% CI, 12.45%–22.4%; I2 = 0%). Overall, 15% (37/213; 95% CI, 10%–20%; I2 = 0%) were ischemic events. Procedure-related morbidity was 8% (20/213; 95% CI, 5%–12%; I2 = 0%). Fusiform or dissecting types had comparable adequate occlusion (116/146 = 83%; 95% CI, 74%–92%; I2 = 48% versus 33/36 = 89%; 95% CI, 80%–98%; I2 = 0%; P  = .31) and complication rates (35/162 = 17%; 95% CI, 10%–25%; I2 = 24% versus 11/51 = 19%; 95% CI, 10%–31%; I2 = 0%; P  = .72). Aneurysm size (&gt;10 versus ≤10 mm) was independently associated with a higher rate of complications (OR = 6.6; 95% CI, 1.3–15; P  = .02). The rate of ischemic events after discontinuation of the antiplatelet therapy was 5% (5/93; 95% CI, 2%–9%; I2 = 0%).

LIMITATIONS: Small and retrospective studies were available for this meta-analysis.

CONCLUSIONS: Unruptured nonsaccular aneurysms located in the posterior and distal anterior circulations can be effectively treated with flow diversion. Nevertheless, treatment-related complications are not negligible, with about 15% ischemic events and 8% morbidity. Larger size (&gt;10 mm) significantly increases the risk of procedure-related adverse events.

AC
:   anterior circulation
FD
:   flow diversion
IQR
:   interquartile range
PC
:   posterior circulation" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node72466--5" data-node-nid="72466" id="top-node-72466--6789125727" data-pisa="ajnr;41/1/134" data-pisa-master="ajnr;41/1/134" data-apath="/ajnr/41/1/134.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Interventional</span></span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Flow-Diversion Treatment for Unruptured Nonsaccular Intracranial Aneurysms of the Posterior and Distal Anterior Circulation: A Meta-Analysis</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">F. Cagnazzo</span>, <span class="highwire-citation-author" data-delta="1">P.-H. Lefevre</span>, <span class="highwire-citation-author" data-delta="2">I. Derraz</span>, <span class="highwire-citation-author" data-delta="3">C. Dargazanli</span>, <span class="highwire-citation-author" data-delta="4">G. Gascou</span>, <span class="highwire-citation-author" data-delta="5">D.T. di Carlo</span>, <span class="highwire-citation-author" data-delta="6">P. Perrini</span>, <span class="highwire-citation-author" data-delta="7">R. Ahmed</span>, <span class="highwire-citation-author" data-delta="8">J.F. Hak</span>, <span class="highwire-citation-author" data-delta="9">C. Riquelme</span>, <span class="highwire-citation-author" data-delta="10">A. Bonafe</span> and <span class="highwire-citation-author" data-delta="11">V. Costalat</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">January 2020,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">41 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">134-139; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A6352 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-72466--6789125727" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">F. Cagnazzo </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BCagnazzo%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Cagnazzo%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BCagnazzo%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-3159-1678" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Cagnazzo</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">P.-H. Lefevre </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=P.-H.%2BLefevre%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lefevre%20P&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AP.-H.%2BLefevre%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6196-3869" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for P.-H. Lefevre</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">I. Derraz </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=I.%2BDerraz%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Derraz%20I&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AI.%2BDerraz%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-0632-3399" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for I. Derraz</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">C. Dargazanli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BDargazanli%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Dargazanli%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BDargazanli%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-1891-9157" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Dargazanli</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">G. Gascou </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G.%2BGascou%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gascou%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AG.%2BGascou%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0817-7324" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for G. Gascou</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">D.T. di Carlo </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Neurosurgery (D.T.d.C., P.P.), University of Pisa, Pisa, Italy.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.T.%2Bdi%2BCarlo%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=di%20Carlo%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AD.T.%2Bdi%2BCarlo%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-7136-4408" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for D.T. di Carlo</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">P. Perrini </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Neurosurgery (D.T.d.C., P.P.), University of Pisa, Pisa, Italy.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=P.%2BPerrini%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Perrini%20P&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AP.%2BPerrini%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-3251-6111" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for P. Perrini</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">R. Ahmed </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BAhmed%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Ahmed%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AR.%2BAhmed%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-2469-8442" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for R. Ahmed</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">J.F. Hak </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.F.%2BHak%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Hak%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.F.%2BHak%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0225-7876" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.F. Hak</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">C. Riquelme </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BRiquelme%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Riquelme%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BRiquelme%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6352-7713" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Riquelme</a></li></ul></div><div class="author-tooltip-10"><div class="author-tooltip-name">A. Bonafe </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BBonafe%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bonafe%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AA.%2BBonafe%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-9187-1375" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for A. Bonafe</a></li></ul></div><div class="author-tooltip-11"><div class="author-tooltip-name">V. Costalat </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Neuroradiology Department (F.C., P.-H.L., I.D., C.D., G.G., R.A., J.F.H., C.R., A.B., V.C.), CHU Gui De Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=V.%2BCostalat%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Costalat%20V&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AV.%2BCostalat%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8428-9101" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for V. Costalat</a></li></ul></div></div></div>  </div>

  
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    <div class="elements-frag-data highwire-markup" id="fig-data"><div id="fig-data-tables" class="group frag-table"><div class="fig-data-title-jump clearfix"><h3 class="fig-data-group-title">Tables</h3><div class="fig-data-jump-links"></div></div><div class="item-list"><ul class="fig-data-list clearfix" id="fragments-table"><li class="first"><div class="element-fig-data clearfix table-caption"><div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="table-expansion " id="T1"><span class="highwire-journal-article-marker-start"></span><div class="table-caption"><ul class="inline table-expansion-links"><li class="view-popup first last"><a href="/highwire/markup/72551/expansion?width=1000&amp;height=500&amp;iframe=true&amp;postprocessors=highwire_tables%2Chighwire_reclass%2Chighwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed" class="colorbox colorbox-load table-expand-popup" rel="gallery-fragment-tables-167645728" data-icon-position="" data-hide-link-title="0">View popup</a></li></ul><span class="table-label">Table 1:</span> <p id="p-26">Outcomes after flow-diversion treatment of unruptured nonsaccular intracranial aneurysms</p><div class="sb-div caption-clear"></div></div><table frame="hsides" id="table-1" alt="Table 1:"><thead valign="bottom" id="thead-1" class="table-vbottom"><tr id="tr-1"><th align="center" rowspan="1" colspan="1" id="th-1" class="table-center">Variables</th><th align="center" rowspan="1" colspan="1" id="th-2" class="table-center">Results of Systematic Review and Meta-Analysis</th><th align="center" rowspan="1" colspan="1" id="th-3" class="table-center">No. of Articles</th><th align="center" rowspan="1" colspan="1" id="th-4" class="table-center">Statistic (95% CI) (I<sup>2</sup>)</th></tr></thead><tbody valign="top" id="tbody-1" class="table-vtop"><tr id="tr-2"><td align="left" rowspan="1" colspan="1" id="td-1" class="table-left">Angiographic outcomes</td></tr><tr id="tr-3"><td align="left" rowspan="1" colspan="1" id="td-2" class="table-left"> Rate of successful stent deployment</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-3" class="table-char">178/181 = 96%</td><td align="char" char="." rowspan="1" colspan="1" id="td-4" class="table-char">11</td><td align="left" rowspan="1" colspan="1" id="td-5" class="table-left">(93–98) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-4"><td align="left" rowspan="1" colspan="1" id="td-6" class="table-left"> Long-term aneurysm adequate occlusion rate</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-7" class="table-char">137/168 = 85.3%</td><td align="char" char="." rowspan="1" colspan="1" id="td-8" class="table-char">12</td><td align="left" rowspan="1" colspan="1" id="td-9" class="table-left">(78.2–92.4) (I<sup>2</sup> = 42.3%)</td></tr><tr id="tr-5"><td align="left" rowspan="1" colspan="1" id="td-10" class="table-left"> Long-term aneurysm complete occlusion rate</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-11" class="table-char">128/168 = 78.8%</td><td align="char" char="." rowspan="1" colspan="1" id="td-12" class="table-char">12</td><td align="left" rowspan="1" colspan="1" id="td-13" class="table-left">(72.8–84.8) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-6"><td align="left" rowspan="1" colspan="1" id="td-14" class="table-left"> Long-term adequate occlusion rate (fusiform aneurysms)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-15" class="table-char">116/146 = 83%</td><td align="char" char="." rowspan="1" colspan="1" id="td-16" class="table-char">11</td><td align="left" rowspan="1" colspan="1" id="td-17" class="table-left">(74–92) (I<sup>2</sup> = 48%)</td></tr><tr id="tr-7"><td align="left" rowspan="1" colspan="1" id="td-18" class="table-left"> Long-term adequate occlusion rate (dissecting aneurysms)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-19" class="table-char">33/36 = 89%</td><td align="char" char="." rowspan="1" colspan="1" id="td-20" class="table-char">4</td><td align="left" rowspan="1" colspan="1" id="td-21" class="table-left">(80–98) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-8"><td align="left" rowspan="1" colspan="1" id="td-22" class="table-left"> Long-term occlusion rate among anterior circulation</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-23" class="table-char">51/61 = 87.5%</td><td align="char" char="." rowspan="1" colspan="1" id="td-24" class="table-char">6</td><td align="left" rowspan="1" colspan="1" id="td-25" class="table-left">(79–95) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-9"><td align="left" rowspan="1" colspan="1" id="td-26" class="table-left"> Long-term occlusion rate among posterior circulation</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-27" class="table-char">86/107 = 83%</td><td align="char" char="." rowspan="1" colspan="1" id="td-28" class="table-char">6</td><td align="left" rowspan="1" colspan="1" id="td-29" class="table-left">(71–95) (I<sup>2</sup> = 60%)</td></tr><tr id="tr-10"><td align="left" rowspan="1" colspan="1" id="td-30" class="table-left"> Long-term adequate occlusion rate (PED)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-31" class="table-char">118/149 = 82%</td><td align="char" char="." rowspan="1" colspan="1" id="td-32" class="table-char">8</td><td align="left" rowspan="1" colspan="1" id="td-33" class="table-left">(75–90) (I<sup>2</sup> = 25%)</td></tr><tr id="tr-11"><td align="left" rowspan="1" colspan="1" id="td-34" class="table-left"> Long-term adequate occlusion rate (other devices)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-35" class="table-char">21/23 = 90%</td><td align="char" char="." rowspan="1" colspan="1" id="td-36" class="table-char">3</td><td align="left" rowspan="1" colspan="1" id="td-37" class="table-left">(81–98) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-12"><td align="left" rowspan="1" colspan="1" id="td-38" class="table-left">Treatment-related complications and clinical outcomes</td></tr><tr id="tr-13"><td align="left" rowspan="1" colspan="1" id="td-39" class="table-left"> Overall treatment-related complications</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-40" class="table-char">41/213 = 17.4%</td><td align="char" char="." rowspan="1" colspan="1" id="td-41" class="table-char">16</td><td align="left" rowspan="1" colspan="1" id="td-42" class="table-left">(12.5–22.4) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-14"><td align="left" rowspan="1" colspan="1" id="td-43" class="table-left"> Transient complications</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-44" class="table-char">21/213 = 9%</td><td align="char" char="." rowspan="1" colspan="1" id="td-45" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-46" class="table-left">(5.6–13) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-15"><td align="left" rowspan="1" colspan="1" id="td-47" class="table-left"> Permanent complications</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-48" class="table-char">20/213 = 8%</td><td align="char" char="." rowspan="1" colspan="1" id="td-49" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-50" class="table-left">(5–12) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-16"><td align="left" rowspan="1" colspan="1" id="td-51" class="table-left"> Ischemic complications</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-52" class="table-char">37/213 = 15%</td><td align="char" char="." rowspan="1" colspan="1" id="td-53" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-54" class="table-left">(10–20) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-17"><td align="left" rowspan="1" colspan="1" id="td-55" class="table-left"> Hemorrhagic complications</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-56" class="table-char">4/213 = 3%</td><td align="char" char="." rowspan="1" colspan="1" id="td-57" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-58" class="table-left">(1.2–6) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-18"><td align="left" rowspan="1" colspan="1" id="td-59" class="table-left"> Treatment-related complications (fusiform aneurysms)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-60" class="table-char">35/162 = 17%</td><td align="char" char="." rowspan="1" colspan="1" id="td-61" class="table-char">11</td><td align="left" rowspan="1" colspan="1" id="td-62" class="table-left">(10–25) (I<sup>2</sup> = 24%)</td></tr><tr id="tr-19"><td align="left" rowspan="1" colspan="1" id="td-63" class="table-left"> Treatment-related complications (dissecting aneurysms)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-64" class="table-char">11/51 = 19%</td><td align="char" char="." rowspan="1" colspan="1" id="td-65" class="table-char">4</td><td align="left" rowspan="1" colspan="1" id="td-66" class="table-left">(10–31) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-20"><td align="left" rowspan="1" colspan="1" id="td-67" class="table-left"> Treatment-related complications among anterior circulation</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-68" class="table-char">13/81 = 14%</td><td align="char" char="." rowspan="1" colspan="1" id="td-69" class="table-char">8</td><td align="left" rowspan="1" colspan="1" id="td-70" class="table-left">(7–22) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-21"><td align="left" rowspan="1" colspan="1" id="td-71" class="table-left"> Treatment-related complications among posterior circulation</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-72" class="table-char">28/132 = 20%</td><td align="char" char="." rowspan="1" colspan="1" id="td-73" class="table-char">8</td><td align="left" rowspan="1" colspan="1" id="td-74" class="table-left">(3–13) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-22"><td align="left" rowspan="1" colspan="1" id="td-75" class="table-left"> Treatment-related complications (PED)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-76" class="table-char">19/110 = 15%</td><td align="char" char="." rowspan="1" colspan="1" id="td-77" class="table-char">9</td><td align="left" rowspan="1" colspan="1" id="td-78" class="table-left">(9–21) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-23"><td align="left" rowspan="1" colspan="1" id="td-79" class="table-left"> Treatment-related complications (other devices)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-80" class="table-char">3/23 = 12%</td><td align="char" char="." rowspan="1" colspan="1" id="td-81" class="table-char">3</td><td align="left" rowspan="1" colspan="1" id="td-82" class="table-left">(6–24) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-24"><td align="left" rowspan="1" colspan="1" id="td-83" class="table-left"> Periprocedural/early complications (within 30 days)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-84" class="table-char">10/213 = 2.5%</td><td align="char" char="." rowspan="1" colspan="1" id="td-85" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-86" class="table-left">(1–4) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-25"><td align="left" rowspan="1" colspan="1" id="td-87" class="table-left"> Delayed complications (after 30 days)</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-88" class="table-char">31/213 = 12%</td><td align="char" char="." rowspan="1" colspan="1" id="td-89" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-90" class="table-left">(7–17) (I<sup>2</sup> = 35%)</td></tr><tr id="tr-26"><td align="left" rowspan="1" colspan="1" id="td-91" class="table-left"> Premature discontinuation of AT and related ischemic events</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-92" class="table-char">5/93 = 5%</td><td align="char" char="." rowspan="1" colspan="1" id="td-93" class="table-char">8</td><td align="left" rowspan="1" colspan="1" id="td-94" class="table-left">(2–9) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-27"><td align="left" rowspan="1" colspan="1" id="td-95" class="table-left"> Treatment-related mortality</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-96" class="table-char">1/213 = 2%</td><td align="char" char="." rowspan="1" colspan="1" id="td-97" class="table-char">15</td><td align="left" rowspan="1" colspan="1" id="td-98" class="table-left">(0.2–3.5) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-28"><td align="left" rowspan="1" colspan="1" id="td-99" class="table-left"> Overall rate of good neurologic outcome</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-100" class="table-char">154/187 = 87%</td><td align="char" char="." rowspan="1" colspan="1" id="td-101" class="table-char">10</td><td align="left" rowspan="1" colspan="1" id="td-102" class="table-left">(79–95) (I<sup>2</sup> = 60%)</td></tr><tr id="tr-29"><td align="left" rowspan="1" colspan="1" id="td-103" class="table-left"> Occlusion of covered branches</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-104" class="table-char">5/72 = 7%</td><td align="char" char="." rowspan="1" colspan="1" id="td-105" class="table-char">10</td><td align="left" rowspan="1" colspan="1" id="td-106" class="table-left">(2–13) (I<sup>2</sup> = 0%)</td></tr><tr id="tr-30"><td align="left" rowspan="1" colspan="1" id="td-107" class="table-left"> Symptoms related to occlusion or impaired flow of covered branches</td><td align="char" char="equal" rowspan="1" colspan="1" id="td-108" class="table-char">3/72 = 3%</td><td align="char" char="." rowspan="1" colspan="1" id="td-109" class="table-char">10</td><td align="left" rowspan="1" colspan="1" id="td-110" class="table-left">(0.5–9) (I<sup>2</sup> = 0%)</td></tr></tbody></table><div class="table-foot"><ul class="table-footnotes"><li class="fn" id="fn-1"><p id="p-27"><strong>Note:</strong>—AT indicates antiplatelet therapy.</p></li></ul></div><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div></div></li><li class="last"><div class="element-fig-data clearfix table-caption"><div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="table-expansion " id="T2"><span class="highwire-journal-article-marker-start"></span><div class="table-caption"><ul class="inline table-expansion-links"><li class="view-popup first last"><a href="/highwire/markup/72565/expansion?width=1000&amp;height=500&amp;iframe=true&amp;postprocessors=highwire_tables%2Chighwire_reclass%2Chighwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed" class="colorbox colorbox-load table-expand-popup" rel="gallery-fragment-tables-167645728" data-icon-position="" data-hide-link-title="0">View popup</a></li></ul><span class="table-label">Table 2:</span> <p id="p-36">Univariate and multivariate analysis of predicting factors for aneurysm occlusion and treatment-related complications</p><div class="sb-div caption-clear"></div></div><table frame="hsides" id="table-2" alt="Table 2:"><thead valign="bottom" id="thead-2" class="table-vbottom"><tr id="tr-31"><th rowspan="2" align="center" colspan="1" id="th-5" class="table-center"></th><th rowspan="2" align="center" colspan="1" id="th-6" class="table-center">Univariate, <em>P</em> Value</th><th rowspan="2" align="center" colspan="1" id="th-7" class="table-center">Univariate, OR</th><th colspan="3" align="center" rowspan="1" id="th-8" class="table-center table-bborder">Multivariate</th></tr><tr id="tr-32"><th align="center" rowspan="1" colspan="1" id="th-9" class="table-center">Odds Ratio</th><th align="center" rowspan="1" colspan="1" id="th-10" class="table-center">95% CI</th><th align="center" rowspan="1" colspan="1" id="th-11" class="table-center"><em>P</em> Value</th></tr></thead><tbody valign="top" id="tbody-2" class="table-vtop"><tr id="tr-33"><td align="left" rowspan="1" colspan="1" id="td-111" class="table-left">Independent variables for occlusion</td><td align="center" rowspan="1" colspan="1" id="td-112" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-113" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-114" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-115" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-116" class="table-center"></td></tr><tr id="tr-34"><td align="left" rowspan="1" colspan="1" id="td-117" class="table-left"> Type of FD (PED vs other)</td><td align="char" char="." rowspan="1" colspan="1" id="td-118" class="table-char">0.22</td><td align="char" char="." rowspan="1" colspan="1" id="td-119" class="table-char">1.2</td><td align="center" rowspan="1" colspan="1" id="td-120" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-121" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-122" class="table-center"></td></tr><tr id="tr-35"><td align="left" rowspan="1" colspan="1" id="td-123" class="table-left"> Patient age (younger than 60 vs older than 60 yr)</td><td align="char" char="." rowspan="1" colspan="1" id="td-124" class="table-char">0.21</td><td align="char" char="." rowspan="1" colspan="1" id="td-125" class="table-char">2.6</td><td align="center" rowspan="1" colspan="1" id="td-126" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-127" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-128" class="table-center"></td></tr><tr id="tr-36"><td align="left" rowspan="1" colspan="1" id="td-129" class="table-left"> Aneurysm size (large vs small)<sup><a id="xref-fn-3-1" class="xref-table-fn" href="#fn-3"><sup>a</sup></a></sup></td><td align="char" char="." rowspan="1" colspan="1" id="td-130" class="table-char">0.13</td><td align="char" char="." rowspan="1" colspan="1" id="td-131" class="table-char">1.7</td><td align="char" char="." rowspan="1" colspan="1" id="td-132" class="table-char">1.5</td><td align="char" char="endash" rowspan="1" colspan="1" id="td-133" class="table-char">0.2–6.4</td><td align="char" char="." rowspan="1" colspan="1" id="td-134" class="table-char">.81</td></tr><tr id="tr-37"><td align="left" rowspan="1" colspan="1" id="td-135" class="table-left"> Type of aneurysm (dissecting vs fusiform)</td><td align="char" char="." rowspan="1" colspan="1" id="td-136" class="table-char">0.06</td><td align="char" char="." rowspan="1" colspan="1" id="td-137" class="table-char">2.5</td><td align="char" char="." rowspan="1" colspan="1" id="td-138" class="table-char">1.7</td><td align="char" char="endash" rowspan="1" colspan="1" id="td-139" class="table-char">0.4–2.4</td><td align="char" char="." rowspan="1" colspan="1" id="td-140" class="table-char">.35</td></tr><tr id="tr-38"><td align="left" rowspan="1" colspan="1" id="td-141" class="table-left"> Aneurysm location (AC vs PC)</td><td align="char" char="." rowspan="1" colspan="1" id="td-142" class="table-char">0.11</td><td align="char" char="." rowspan="1" colspan="1" id="td-143" class="table-char">3.1</td><td align="char" char="." rowspan="1" colspan="1" id="td-144" class="table-char">0.5</td><td align="char" char="endash" rowspan="1" colspan="1" id="td-145" class="table-char">0.2–0.7</td><td align="char" char="." rowspan="1" colspan="1" id="td-146" class="table-char">.38</td></tr><tr id="tr-39"><td align="left" rowspan="1" colspan="1" id="td-147" class="table-left">Independent variables for complications</td><td align="center" rowspan="1" colspan="1" id="td-148" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-149" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-150" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-151" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-152" class="table-center"></td></tr><tr id="tr-40"><td align="left" rowspan="1" colspan="1" id="td-153" class="table-left"> Type of FD (PED vs other)</td><td align="char" char="." rowspan="1" colspan="1" id="td-154" class="table-char">0.94</td><td align="char" char="." rowspan="1" colspan="1" id="td-155" class="table-char">1.1</td><td align="center" rowspan="1" colspan="1" id="td-156" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-157" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-158" class="table-center"></td></tr><tr id="tr-41"><td align="left" rowspan="1" colspan="1" id="td-159" class="table-left"> Patient age (younger than 60 vs older than 60 yr)</td><td align="char" char="." rowspan="1" colspan="1" id="td-160" class="table-char">0.46</td><td align="char" char="." rowspan="1" colspan="1" id="td-161" class="table-char">1.5</td><td align="center" rowspan="1" colspan="1" id="td-162" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-163" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-164" class="table-center"></td></tr><tr id="tr-42"><td align="left" rowspan="1" colspan="1" id="td-165" class="table-left"> Aneurysm size (large vs small)<sup><a id="xref-fn-3-2" class="xref-table-fn" href="#fn-3"><sup>a</sup></a></sup></td><td align="char" char="." rowspan="1" colspan="1" id="td-166" class="table-char">0.03</td><td align="char" char="." rowspan="1" colspan="1" id="td-167" class="table-char">4.5</td><td align="char" char="." rowspan="1" colspan="1" id="td-168" class="table-char">6.6</td><td align="char" char="endash" rowspan="1" colspan="1" id="td-169" class="table-char">1.3–15</td><td align="char" char="." rowspan="1" colspan="1" id="td-170" class="table-char">.02</td></tr><tr id="tr-43"><td align="left" rowspan="1" colspan="1" id="td-171" class="table-left"> Type of aneurysm (fusiform vs dissecting)</td><td align="char" char="." rowspan="1" colspan="1" id="td-172" class="table-char">0.27</td><td align="char" char="." rowspan="1" colspan="1" id="td-173" class="table-char">0.8</td><td align="center" rowspan="1" colspan="1" id="td-174" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-175" class="table-center"></td><td align="center" rowspan="1" colspan="1" id="td-176" class="table-center"></td></tr><tr id="tr-44"><td align="left" rowspan="1" colspan="1" id="td-177" class="table-left"> Aneurysm location (AC vs PC)</td><td align="char" char="." rowspan="1" colspan="1" id="td-178" class="table-char">0.04</td><td align="char" char="." rowspan="1" colspan="1" id="td-179" class="table-char">0.7</td><td align="char" char="." rowspan="1" colspan="1" id="td-180" class="table-char">0.3</td><td align="char" char="endash" rowspan="1" colspan="1" id="td-181" class="table-char">0.6–1.8</td><td align="char" char="." rowspan="1" colspan="1" id="td-182" class="table-char">.09</td></tr></tbody></table><div class="table-foot"><ul class="table-footnotes"><li class="fn" id="fn-2"><p id="p-37"><strong>Note:</strong>—OR indicates odds ratio.</p></li><li class="fn-other" id="fn-3"><p id="p-38"><a class="rev-xref" href="#xref-fn-3-1">↵</a><span class="fn-label">a</span> Small aneurysms, ≤10 mm; large aneurysms, ≥10 mm.</p></li></ul></div><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div></div></li></ul></div></div></div>  </div>

  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2020, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">41 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">134-139; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A6352 </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Cagnazzo</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">P.-H.</span> <span class="nlm-surname">Lefevre</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Derraz</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Dargazanli</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Gascou</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">D.T.</span> <span class="nlm-surname">di Carlo</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">P.</span> <span class="nlm-surname">Perrini</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Ahmed</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">J.F.</span> <span class="nlm-surname">Hak</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Riquelme</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Bonafe</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Costalat</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2020, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">41 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">134-139; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A6352 </span></div>
  
  
  
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