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<meta name="DC.Title" content="Signal of Carotid Intraplaque Hemorrhage on MR T1-Weighted Imaging: Association with Acute Cerebral Infarct" />
<meta name="DC.Identifier" content="10.3174/ajnr.A6498" />
<meta name="DC.Date" content="2020-05-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2020 by American Journal of Neuroradiology. Indicates open access to non-subscribers at www.ajnr.org" />
<meta name="DC.AccessRights" content="open-access" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Identifying the mere presence of carotid intraplaque hemorrhage would be insufficient to accurately discriminate the presence of acute cerebral infarct. We aimed to investigate the association between signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted MR imaging and acute cerebral infarct in patients with hemorrhagic carotid plaques using MR vessel wall imaging.

MATERIALS AND METHODS: Symptomatic patients with carotid intraplaque hemorrhage were included. The signal intensity ratios of carotid intraplaque hemorrhage against muscle on T1-weighted, TOF, and MPRAGE images were measured. The acute cerebral infarct was determined on the hemisphere ipsilateral to the carotid intraplaque hemorrhage. The association between signal intensity ratios of carotid intraplaque hemorrhage and acute cerebral infarct was analyzed.

RESULTS: Of 109 included patients (mean, 66.8 ± 9.9 years of age; 96 men), 40 (36.7%) had acute cerebral infarct. Patients with acute cerebral infarct had significantly higher signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted images than those without (Median, 1.44; 25–75 Percentiles, 1.14-1.82 versus Median, 1.27; 25–75 Percentiles, 1.06–1.55, P = .022). Logistic regression analysis revealed that the signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images was significantly associated with acute cerebral infarct before (OR, 4.08; 95% CI, 1.34–12.40; P = .013) and after (OR, 3.34; 95% CI, 1.08–10.31; P = .036) adjustment for clinical confounding factors. However, this association was not significant when further adjusted for occlusion of the carotid artery ( P = .058) and volumes of intraplaque hemorrhage and lipid-rich necrotic core ( P = .458).

CONCLUSIONS: The signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images is associated with acute cerebral infarct in symptomatic patients with carotid hemorrhagic plaques. This association is independent of traditional risk factors but not of the size of plaque composition. The possibility of applying T1 signals of carotid intraplaque hemorrhage to predict subsequent cerebrovascular ischemic events needs to be prospectively verified.

ACI
:   acute cerebral infarct
IPH
:   intraplaque hemorrhage
LRNC
:   lipid-rich necrotic core
SIR
:   signal intensity ratio" />
<meta name="DC.Contributor" content="D. Yang" />
<meta name="DC.Contributor" content="Y. Liu" />
<meta name="DC.Contributor" content="Y. Han" />
<meta name="DC.Contributor" content="D. Li" />
<meta name="DC.Contributor" content="W. Wang" />
<meta name="DC.Contributor" content="R. Li" />
<meta name="DC.Contributor" content="C. Yuan" />
<meta name="DC.Contributor" content="X. Zhao" />
<meta name="article:published_time" content="2020-05-01" />
<meta name="article:section" content="Extracranial Vascular" />
<meta name="citation_title" content="Signal of Carotid Intraplaque Hemorrhage on MR T1-Weighted Imaging: Association with Acute Cerebral Infarct" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Identifying the mere presence of carotid intraplaque hemorrhage would be insufficient to accurately discriminate the presence of acute cerebral infarct. We aimed to investigate the association between signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted MR imaging and acute cerebral infarct in patients with hemorrhagic carotid plaques using MR vessel wall imaging.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Symptomatic patients with carotid intraplaque hemorrhage were included. The signal intensity ratios of carotid intraplaque hemorrhage against muscle on T1-weighted, TOF, and MPRAGE images were measured. The acute cerebral infarct was determined on the hemisphere ipsilateral to the carotid intraplaque hemorrhage. The association between signal intensity ratios of carotid intraplaque hemorrhage and acute cerebral infarct was analyzed.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Of 109 included patients (mean, 66.8 ± 9.9 years of age; 96 men), 40 (36.7%) had acute cerebral infarct. Patients with acute cerebral infarct had significantly higher signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted images than those without (Median, 1.44; 25–75 Percentiles, 1.14-1.82 versus Median, 1.27; 25–75 Percentiles, 1.06–1.55, &lt;i&gt;P&lt;/i&gt; = .022). Logistic regression analysis revealed that the signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images was significantly associated with acute cerebral infarct before (OR, 4.08; 95% CI, 1.34–12.40; &lt;i&gt;P&lt;/i&gt; = .013) and after (OR, 3.34; 95% CI, 1.08–10.31; &lt;i&gt;P&lt;/i&gt; = .036) adjustment for clinical confounding factors. However, this association was not significant when further adjusted for occlusion of the carotid artery (&lt;i&gt;P&lt;/i&gt; = .058) and volumes of intraplaque hemorrhage and lipid-rich necrotic core (&lt;i&gt;P&lt;/i&gt; = .458).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;The signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images is associated with acute cerebral infarct in symptomatic patients with carotid hemorrhagic plaques. This association is independent of traditional risk factors but not of the size of plaque composition. The possibility of applying T1 signals of carotid intraplaque hemorrhage to predict subsequent cerebrovascular ischemic events needs to be prospectively verified.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="2020/05/01" />
<meta name="citation_mjid" content="ajnr;41/5/836" />
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<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
<meta name="citation_doi" content="10.3174/ajnr.A6498" />
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<meta name="citation_volume" content="41" />
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<meta name="citation_article_type" content="Research Article" />
<meta name="citation_section" content="Extracranial Vascular" />
<meta name="citation_firstpage" content="836" />
<meta name="citation_lastpage" content="843" />
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<meta name="citation_author" content="D. Yang" />
<meta name="citation_author_institution" content="aFrom the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China" />
<meta name="citation_author_institution" content="bDepartment of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-6528-0846" />
<meta name="citation_author" content="Y. Liu" />
<meta name="citation_author_institution" content="cDepartment of Radiology (Y.L., W.W.), The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-0650-0036" />
<meta name="citation_author" content="Y. Han" />
<meta name="citation_author_institution" content="aFrom the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China" />
<meta name="citation_author_institution" content="bDepartment of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China" />
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<meta name="citation_author" content="D. Li" />
<meta name="citation_author_institution" content="aFrom the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China" />
<meta name="citation_author_institution" content="bDepartment of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-5272-1473" />
<meta name="citation_author" content="W. Wang" />
<meta name="citation_author_institution" content="cDepartment of Radiology (Y.L., W.W.), The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-4345-1608" />
<meta name="citation_author" content="R. Li" />
<meta name="citation_author_institution" content="bDepartment of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China" />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0001-6258-8258" />
<meta name="citation_author" content="C. Yuan" />
<meta name="citation_author_institution" content="dDepartment of Radiology (C.Y.), University of Washington, Seattle, Washington." />
<meta name="citation_author_orcid" content="https://orcid.org/0000-0002-6154-5106" />
<meta name="citation_author" content="X. Zhao" />
<meta name="citation_author_institution" content="bDepartment of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China" />
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<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=L. Liu;citation_author=D. Wang;citation_author=KS. Wong;citation_title=Stroke and stroke care in China: huge burden, significant workload, and a national priority;citation_volume=42;citation_year=2011;citation_pmid=22052510;citation_doi=10.1161/STROKEAHA.111.635755" />
<meta name="citation_reference" content="citation_journal_title=JAMA;citation_journal_abbrev=JAMA;citation_author=HJ. Barnett;citation_author=RW. Gunton;citation_author=M. Eliasziw;citation_title=Causes and Severity of Ischemic Stroke in Patients With Internal Carotid Artery Stenosis;citation_pages=1429-1436;citation_volume=283;citation_year=2000;citation_issue=11;citation_pmid=10732932;citation_doi=10.1001/jama.283.11.1429" />
<meta name="citation_reference" content="citation_journal_title=AJNR Am J Neuroradiol;citation_author=HR. Underhill;citation_author=TS. Hatsukami;citation_author=J. Cai;citation_title=A noninvasive imaging approach to assess plaque severity: the carotid atherosclerosis score;citation_volume=31;citation_year=2010;citation_pmid=20093315;citation_doi=10.3174/ajnr.A2007" />
<meta name="citation_reference" content="citation_journal_title=Ann Neurol;citation_author=AA. Hosseini;citation_author=N. Kandiyil;citation_author=ST. Macsweeney;citation_title=Carotid plaque hemorrhage on magnetic resonance imaging strongly predicts recurrent ischemia and stroke;citation_pages=774-84;citation_volume=73;citation_year=2013;citation_pmid=23463579;citation_doi=10.1002/ana.23876" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=N. Takaya;citation_author=C. Yuan;citation_author=B. Chu;citation_title=Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI—initial results;citation_volume=37;citation_year=2006;citation_pmid=16469957;citation_doi=10.1161/01.STR.0000204638.91099.91" />
<meta name="citation_reference" content="citation_journal_title=Radiology;citation_author=N. Singh;citation_author=AR. Moody;citation_author=DJ. Gladstone;citation_title=Moderate carotid artery stenosis: MR imaging–depicted intraplaque hemorrhage predicts risk of cerebrovascular ischemic events in asymptomatic men;citation_volume=252;citation_year=2009;citation_pmid=19508983;citation_doi=10.1148/radiol.2522080792" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=JS. McNally;citation_author=MS. McLaughlin;citation_author=PJ. Hinckley;citation_title=Intraluminal thrombus, intraplaque hemorrhage, plaque thickness, and current smoking optimally predict carotid stroke;citation_volume=46;citation_year=2015;citation_pmid=25406146;citation_doi=10.1161/STROKEAHA.114.006286" />
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<meta name="citation_reference" content="citation_journal_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_author=L. Dong;citation_author=HR. Underhill;citation_author=W. Yu;citation_title=Geometric and compositional appearance of atheroma in an angiographically normal carotid artery in patients with atherosclerosis.;citation_pages=311-316;citation_volume=31;citation_year=2010;citation_issue=2;citation_pmid=19779001;citation_doi=10.3174/ajnr.A1793" />
<meta name="citation_reference" content="citation_journal_title=Eur J Radiol;citation_author=Y. Cai;citation_author=L. He;citation_author=C. Yuan;citation_title=Atherosclerotic plaque features and distribution in bilateral carotid arteries of asymptomatic elderly population: a 3D multicontrast MR vessel wall imaging study;citation_pages=6-11;citation_volume=96;citation_year=2017;citation_pmid=29103477;citation_doi=10.1016/j.ejrad.2017.09.004" />
<meta name="citation_reference" content="citation_journal_title=JACC: Cardiovascular Imaging;citation_journal_abbrev=JIMG;citation_author=J. Sun;citation_author=HR. Underhill;citation_author=DS. Hippe;citation_title=Sustained Acceleration in Carotid Atherosclerotic Plaque Progression With Intraplaque Hemorrhage: A Long-Term Time Course Study;citation_pages=798-804;citation_volume=5;citation_year=2012;citation_issue=8;citation_pmid=22897993;citation_doi=10.1016/j.jcmg.2012.03.014" />
<meta name="citation_reference" content="citation_journal_title=Circulation;citation_author=N. Takaya;citation_author=C. Yuan;citation_author=B. Chu;citation_title=Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study;citation_volume=111;citation_year=2005;citation_pmid=15911695;citation_doi=10.1161/CIRCULATIONAHA.104.504167" />
<meta name="citation_reference" content="citation_journal_title=Circulation;citation_author=AR. Moody;citation_author=RE. Murphy;citation_author=PS. Morgan;citation_title=Characterization of complicated carotid plaque with magnetic resonance direct thrombus imaging in patients with cerebral ischemia;citation_volume=107;citation_year=2003;citation_pmid=12796133;citation_doi=10.1161/01.CIR.0000074222.61572.44" />
<meta name="citation_reference" content="citation_journal_title=J Clin Neurosci;citation_author=K. Yamada;citation_author=S. Yoshimura;citation_author=M. Shirakawa;citation_title=Asymptomatic moderate carotid artery stenosis with intraplaque hemorrhage: progression of degree of stenosis and new ischemic stroke;citation_pages=95-99;citation_volume=63;citation_year=2019;citation_pmid=30732983;citation_doi=10.1016/j.jocn.2019.01.033" />
<meta name="citation_reference" content="citation_journal_title=Cerebrovasc Dis;citation_author=K. Yamada;citation_author=M. Kawasaki;citation_author=S. Yoshimura;citation_title=High-intensity signal in carotid plaque on routine 3D-TOF-MRA is a risk factor of ischemic stroke;citation_pages=13-18;citation_volume=41;citation_year=2016;citation_pmid=26580667;citation_doi=10.1159/000441094" />
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<meta name="citation_reference" content="citation_journal_title=Stroke Vasc Neurol;citation_author=CARE-II Investigators;citation_title=Chinese Atherosclerosis Risk Evaluation (CARE II) study: a novel cross-sectional, multicentre study of the prevalence of high-risk atherosclerotic carotid plaque in Chinese patients with ischaemic cerebrovascular events-design and rationale;citation_volume=2;citation_year=2017;citation_pmid=28959486;citation_doi=10.1136/svn-2016-000053" />
<meta name="citation_reference" content="citation_journal_title=Topics in magnetic resonance imaging :  TMRI;citation_journal_abbrev=Top Magn Reson Imaging;citation_author=W. Kerwin;citation_author=D. Xu;citation_author=F. Liu;citation_title=Magnetic resonance imaging of carotid atherosclerosis: plaque analysis.;citation_pages=371-378;citation_volume=18;citation_year=2007;citation_issue=5;citation_pmid=18025991;citation_doi=10.1097/rmr.0b013e3181598d9d" />
<meta name="citation_reference" content="citation_journal_title=Circulation;citation_author=JM. Cai;citation_author=TS. Hatsukami;citation_author=MS. Ferguson;citation_title=Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging;citation_volume=106;citation_year=2002;citation_pmid=12221054;citation_doi=10.1161/01.CIR.0000028591.44554.F9" />
<meta name="citation_reference" content="citation_journal_title=Eur Radiol;citation_author=D. Li;citation_author=H. Zhao;citation_author=X. Chen;citation_title=Identification of intraplaque haemorrhage in carotid artery by simultaneous non-contrast angiography and intraPlaque haemorrhage (SNAP) imaging: a magnetic resonance vessel wall imaging study;citation_pages=1681-86;citation_volume=28;citation_year=2018;citation_pmid=29098439;citation_doi=10.1007/s00330-017-5096-1" />
<meta name="citation_reference" content="citation_journal_title=J Stroke Cerebrovasc Dis;citation_author=A. Eto;citation_author=Y. Kinoshita;citation_author=Y. Matsumoto;citation_title=Relationship between the carotid plaque T1 relaxation time and the plaque-to-muscle signal intensity ratio on black-blood magnetic resonance imaging scans;citation_pages=2580-84;citation_volume=25;citation_year=2016;citation_pmid=27567294;citation_doi=10.1016/j.jstrokecerebrovasdis.2016.06.041" />
<meta name="citation_reference" content="North American Symptomatic Carotid Endarterectomy Trial: methods, patient characteristics, and progress. Stroke 1991;22:711–20 10.1161/01.str.22.6.711 2057968" />
<meta name="citation_reference" content="citation_journal_title=J Hypertens;citation_author=TC. Turin;citation_author=T. Okamura;citation_author=AR. Afzal;citation_title=Hypertension and lifetime risk of stroke;citation_pages=116-22;citation_volume=34;citation_year=2016;citation_pmid=26556566;citation_doi=10.1097/HJH.0000000000000753" />
<meta name="citation_reference" content="citation_journal_title=N Engl J Med;citation_author=GBD 2016 Lifetime Risk of Stroke Collaborators.;citation_title=Global, regional, and country-specific lifetime risks of stroke;citation_pages=2429-37;citation_volume=379;citation_year=2018;citation_pmid=http://www.n;citation_doi=10.1056/NEJMoa1804492" />
<meta name="citation_reference" content="citation_journal_title=Lancet;citation_author=M. Naghavi;citation_author=AA. Abajobir;citation_author=C. Abbafati;citation_title=Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study;citation_volume=390;citation_year=2017;citation_doi=10.1016/S0140-6736(17)32152-9" />
<meta name="citation_reference" content="citation_journal_title=JAMA;citation_journal_abbrev=JAMA;citation_author=PA. Wolf;citation_author=RB. D’Agostino;citation_author=WB. Kannel;citation_title=Cigarette Smoking as a Risk Factor for Stroke: The Framingham Study;citation_pages=1025-1029;citation_volume=259;citation_year=1988;citation_issue=7;citation_pmid=3339799;citation_doi=10.1001/jama.1988.03720070025028" />
<meta name="citation_reference" content="citation_journal_title=Lancet;citation_journal_abbrev=Lancet;citation_author=GA. Donnan;citation_author=JJ. McNeil;citation_author=MA. Adena;citation_title=Smoking as a risk factor for cerebral ischaemia.;citation_pages=643-647;citation_volume=2;citation_year=1989;citation_issue=8664;citation_pmid=2570900;citation_doi=10.1016/S0140-6736(89)90894-5" />
<meta name="citation_reference" content="citation_journal_title=J Appl Physiol;citation_author=C. Li;citation_author=H. Sun;citation_author=DM. Arrick;citation_title=Chronic nicotine exposure exacerbates transient focal cerebral ischemia-induced brain injury;citation_volume=120;citation_year=2016;citation_pmid=26662051;citation_doi=10.1152/japplphysiol.00663.2015" />
<meta name="citation_reference" content="citation_journal_title=Clin Neurol Neurosurg;citation_author=K. Takemoto;citation_author=T. Ueba;citation_author=K. Takano;citation_title=Quantitative evaluation using the plaque/muscle ratio index panels predicts plaque type and risk of embolism in patients undergoing carotid artery stenting;citation_pages=1298-1303;citation_volume=115;citation_year=2013;citation_pmid=23273382;citation_doi=10.1016/j.clineuro.2012.12.001" />
<meta name="citation_reference" content="citation_journal_title=J Neurosurg;citation_author=Y. Kurosaki;citation_author=K. Yoshida;citation_author=R. Fukumitsu;citation_title=Carotid artery plaque assessment using quantitative expansive remodeling evaluation and MRI plaque signal intensity;citation_pages=736-42;citation_volume=124;citation_year=2016;citation_pmid=26361279;citation_doi=10.3171/2015.2.JNS142783" />
<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=B. Chu;citation_author=A. Kampschulte;citation_author=MS. Ferguson;citation_title=Hemorrhage in the atherosclerotic carotid plaque: a high-resolution MRI study;citation_volume=35;citation_year=2004;citation_pmid=15060318;citation_doi=10.1161/01.STR.0000125856.25309.86" />
<meta name="citation_reference" content="citation_journal_title=Radiology;citation_author=G. Leung;citation_author=AR. Moody;citation_title=MR imaging depicts oxidative stress induced by methemoglobin;citation_volume=257;citation_year=2010;citation_pmid=20829533;citation_doi=10.1148/radiol.10100416" />
<meta name="citation_reference" content="citation_journal_title=J Atheroscler Thromb;citation_author=Y. Cui;citation_author=H. Qiao;citation_author=L. Ma;citation_title=Association of age and size of carotid artery intraplaque hemorrhage and minor fibrous cap disruption: a high-resolution magnetic resonance imaging study;citation_pages=1222-30;citation_volume=25;citation_year=2018;citation_pmid=29669957;citation_doi=10.5551/jat.43679" />
<meta name="citation_reference" content="citation_journal_title=Eur J Radiol;citation_author=H. Zhao;citation_author=X. Zhao;citation_author=X. Liu;citation_title=Association of carotid atherosclerotic plaque features with acute ischemic stroke: a magnetic resonance imaging study;citation_pages=e465-70;citation_volume=82;citation_year=2013;citation_pmid=23680156;citation_doi=10.1016/j.ejrad.2013.04.014" />
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<meta name="twitter:title" content="Signal of Carotid Intraplaque Hemorrhage on MR T1-Weighted Imaging: Association with Acute Cerebral Infarct" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Identifying the mere presence of carotid intraplaque hemorrhage would be insufficient to accurately discriminate the presence of acute cerebral infarct. We aimed to investigate the association between signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted MR imaging and acute cerebral infarct in patients with hemorrhagic carotid plaques using MR vessel wall imaging.

MATERIALS AND METHODS: Symptomatic patients with carotid intraplaque hemorrhage were included. The signal intensity ratios of carotid intraplaque hemorrhage against muscle on T1-weighted, TOF, and MPRAGE images were measured. The acute cerebral infarct was determined on the hemisphere ipsilateral to the carotid intraplaque hemorrhage. The association between signal intensity ratios of carotid intraplaque hemorrhage and acute cerebral infarct was analyzed.

RESULTS: Of 109 included patients (mean, 66.8 ± 9.9 years of age; 96 men), 40 (36.7%) had acute cerebral infarct. Patients with acute cerebral infarct had significantly higher signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted images than those without (Median, 1.44; 25–75 Percentiles, 1.14-1.82 versus Median, 1.27; 25–75 Percentiles, 1.06–1.55, P = .022). Logistic regression analysis revealed that the signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images was significantly associated with acute cerebral infarct before (OR, 4.08; 95% CI, 1.34–12.40; P = .013) and after (OR, 3.34; 95% CI, 1.08–10.31; P = .036) adjustment for clinical confounding factors. However, this association was not significant when further adjusted for occlusion of the carotid artery ( P = .058) and volumes of intraplaque hemorrhage and lipid-rich necrotic core ( P = .458).

CONCLUSIONS: The signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images is associated with acute cerebral infarct in symptomatic patients with carotid hemorrhagic plaques. This association is independent of traditional risk factors but not of the size of plaque composition. The possibility of applying T1 signals of carotid intraplaque hemorrhage to predict subsequent cerebrovascular ischemic events needs to be prospectively verified.

ACI
:   acute cerebral infarct
IPH
:   intraplaque hemorrhage
LRNC
:   lipid-rich necrotic core
SIR
:   signal intensity ratio" />
<meta name="og-title" property="og:title" content="Signal of Carotid Intraplaque Hemorrhage on MR T1-Weighted Imaging: Association with Acute Cerebral Infarct" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/41/5/836" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Identifying the mere presence of carotid intraplaque hemorrhage would be insufficient to accurately discriminate the presence of acute cerebral infarct. We aimed to investigate the association between signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted MR imaging and acute cerebral infarct in patients with hemorrhagic carotid plaques using MR vessel wall imaging.

MATERIALS AND METHODS: Symptomatic patients with carotid intraplaque hemorrhage were included. The signal intensity ratios of carotid intraplaque hemorrhage against muscle on T1-weighted, TOF, and MPRAGE images were measured. The acute cerebral infarct was determined on the hemisphere ipsilateral to the carotid intraplaque hemorrhage. The association between signal intensity ratios of carotid intraplaque hemorrhage and acute cerebral infarct was analyzed.

RESULTS: Of 109 included patients (mean, 66.8 ± 9.9 years of age; 96 men), 40 (36.7%) had acute cerebral infarct. Patients with acute cerebral infarct had significantly higher signal intensity ratios of carotid intraplaque hemorrhage on T1-weighted images than those without (Median, 1.44; 25–75 Percentiles, 1.14-1.82 versus Median, 1.27; 25–75 Percentiles, 1.06–1.55, P = .022). Logistic regression analysis revealed that the signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images was significantly associated with acute cerebral infarct before (OR, 4.08; 95% CI, 1.34–12.40; P = .013) and after (OR, 3.34; 95% CI, 1.08–10.31; P = .036) adjustment for clinical confounding factors. However, this association was not significant when further adjusted for occlusion of the carotid artery ( P = .058) and volumes of intraplaque hemorrhage and lipid-rich necrotic core ( P = .458).

CONCLUSIONS: The signal intensity ratio of carotid intraplaque hemorrhage on T1-weighted images is associated with acute cerebral infarct in symptomatic patients with carotid hemorrhagic plaques. This association is independent of traditional risk factors but not of the size of plaque composition. The possibility of applying T1 signals of carotid intraplaque hemorrhage to predict subsequent cerebrovascular ischemic events needs to be prospectively verified.

ACI
:   acute cerebral infarct
IPH
:   intraplaque hemorrhage
LRNC
:   lipid-rich necrotic core
SIR
:   signal intensity ratio" />
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 2020,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">41 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">836-843; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A6498 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-75140--6862595077" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">D. Yang </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.%2BYang%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Yang%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AD.%2BYang%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6528-0846" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for D. Yang</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Y. Liu </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Radiology (Y.L., W.W.), The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.%2BLiu%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Liu%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AY.%2BLiu%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0650-0036" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Y. Liu</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">Y. Han </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.%2BHan%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Han%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AY.%2BHan%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6207-8987" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Y. Han</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">D. Li </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Beijing Institute of Brain Disorders (D.Y., Y.H., D.L.), Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China</div><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.%2BLi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Li%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AD.%2BLi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-5272-1473" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for D. Li</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">W. Wang </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Radiology (Y.L., W.W.), The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=W.%2BWang%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Wang%20W&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AW.%2BWang%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-4345-1608" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for W. 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Li </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Biomedical Engineering (D.Y., Y.H., D.L., R.L., X.Z.), Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BLi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Li%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AR.%2BLi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6258-8258" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for R. 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Yuan </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Radiology (C.Y.), University of Washington, Seattle, Washington.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BYuan%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Yuan%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BYuan%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6154-5106" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 41</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 5 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 May 2020 </div></div>
      
      
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