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<meta name="DC.Title" content="A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions" />
<meta name="DC.Identifier" content="10.3174/ajnr.A7180" />
<meta name="DC.Date" content="2021-08-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2021 by American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Rescue endovascular and pharmacologic approaches are increasingly being adopted after recanalization failure of acute large-vessel occlusion strokes with mechanical thrombectomy, with encouraging results. The safety and efficacy of glycoprotein IIb/IIIa inhibitors in ischemic stroke have been investigated, though cangrelor, a recent intravenous P2Y12-receptor inhibitor with a rapid onset/offset of action and a short half-life, may be a valuable option. We compared the safety and efficacy of cangrelor with those of glycoprotein IIb/IIIa inhibitors for refractory occlusions.

MATERIALS AND METHODS: We performed a retrospective analysis of the ongoing prospective, multicenter, observational Endovascular Treatment in Ischemic Stroke Registry in France between May 2012 and February 2020. Refractory intracranial occlusions of the anterior and posterior circulation were included and defined as recanalization failure of large-vessel occlusion stroke, perioperative target artery reocclusion, or high risk of early reocclusion related to an arterial wall lesion. The primary end point was a favorable outcome, defined as a 90-day mRS of 0–2. Secondary end points were reperfusion, intracranial hemorrhage, and procedural complications.

RESULTS: Among 69 patients, 15 were treated with cangrelor, and 54, with glycoprotein IIb/IIIa inhibitors. The favorable outcome (adjusted OR = 2.22; 95% CI, 0.42–11.75; P = .348) and mortality (adjusted OR = 0.44; 95% CI, 0.06–3.16; P = .411) rates were similar in both groups. There was no difference in the rates of any intracranial hemorrhage (adjusted OR = 0.40; 95% CI, 0.08–2.09; P = .280), symptomatic intracranial hemorrhage (6.7% versus 0.0%, P = .058), or procedural complications (6.7% versus 20.4%, P = .215). Reperfusion rates were higher in the cangrelor group, though the difference did not reach statistical significance (93.3% versus 75.0% for modified TICI 2b–3; adjusted OR =10.88; 95% CI, 0.96–123.84; P = .054).

CONCLUSIONS: Cangrelor seems to be as safe as glycoprotein IIb/IIIa inhibitors for managing refractory intracranial occlusion and leads to satisfactory brain reperfusion. Cangrelor is a promising agent in this setting, and additional studies are warranted to confirm our findings.

ASA
:   acetylsalicylic acid
GPIIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
mTICI
:   modified TICI
sICH
:   symptomatic intracranial hemorrhage" />
<meta name="DC.Contributor" content="G. Marnat" />
<meta name="DC.Contributor" content="F. Delvoye" />
<meta name="DC.Contributor" content="S. Finitsis" />
<meta name="DC.Contributor" content="B. Lapergue" />
<meta name="DC.Contributor" content="F. Gariel" />
<meta name="DC.Contributor" content="A. Consoli" />
<meta name="DC.Contributor" content="J.-P. Desilles" />
<meta name="DC.Contributor" content="M. Mazighi" />
<meta name="DC.Contributor" content="C. Dargazanli" />
<meta name="DC.Contributor" content="R. Bourcier" />
<meta name="DC.Contributor" content="J. Darcourt" />
<meta name="DC.Contributor" content="V. Chalumeau" />
<meta name="DC.Contributor" content="M. Elhorany" />
<meta name="DC.Contributor" content="F. Clarençon" />
<meta name="DC.Contributor" content="S. Richard" />
<meta name="DC.Contributor" content="B. Gory" />
<meta name="DC.Contributor" content="I. Sibon" />
<meta name="DC.Contributor" content="on behalf of the ETIS Investigators" />
<meta name="article:published_time" content="2021-08-01" />
<meta name="article:section" content="Interventional" />
<meta name="citation_title" content="A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Rescue endovascular and pharmacologic approaches are increasingly being adopted after recanalization failure of acute large-vessel occlusion strokes with mechanical thrombectomy, with encouraging results. The safety and efficacy of glycoprotein IIb/IIIa inhibitors in ischemic stroke have been investigated, though cangrelor, a recent intravenous P2Y12-receptor inhibitor with a rapid onset/offset of action and a short half-life, may be a valuable option. We compared the safety and efficacy of cangrelor with those of glycoprotein IIb/IIIa inhibitors for refractory occlusions.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;We performed a retrospective analysis of the ongoing prospective, multicenter, observational Endovascular Treatment in Ischemic Stroke Registry in France between May 2012 and February 2020. Refractory intracranial occlusions of the anterior and posterior circulation were included and defined as recanalization failure of large-vessel occlusion stroke, perioperative target artery reocclusion, or high risk of early reocclusion related to an arterial wall lesion. The primary end point was a favorable outcome, defined as a 90-day mRS of 0–2. Secondary end points were reperfusion, intracranial hemorrhage, and procedural complications.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Among 69 patients, 15 were treated with cangrelor, and 54, with glycoprotein IIb/IIIa inhibitors. The favorable outcome (adjusted OR = 2.22; 95% CI, 0.42–11.75; &lt;i&gt;P&lt;/i&gt; = .348) and mortality (adjusted OR = 0.44; 95% CI, 0.06–3.16; &lt;i&gt;P&lt;/i&gt; = .411) rates were similar in both groups. There was no difference in the rates of any intracranial hemorrhage (adjusted OR = 0.40; 95% CI, 0.08–2.09; &lt;i&gt;P&lt;/i&gt; = .280), symptomatic intracranial hemorrhage (6.7% versus 0.0%, &lt;i&gt;P&lt;/i&gt; = .058), or procedural complications (6.7% versus 20.4%, &lt;i&gt;P&lt;/i&gt; = .215). Reperfusion rates were higher in the cangrelor group, though the difference did not reach statistical significance (93.3% versus 75.0% for modified TICI 2b–3; adjusted OR =10.88; 95% CI, 0.96–123.84; &lt;i&gt;P&lt;/i&gt; = .054).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Cangrelor seems to be as safe as glycoprotein IIb/IIIa inhibitors for managing refractory intracranial occlusion and leads to satisfactory brain reperfusion. Cangrelor is a promising agent in this setting, and additional studies are warranted to confirm our findings.&lt;/p&gt;" />
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<meta name="twitter:title" content="A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Rescue endovascular and pharmacologic approaches are increasingly being adopted after recanalization failure of acute large-vessel occlusion strokes with mechanical thrombectomy, with encouraging results. The safety and efficacy of glycoprotein IIb/IIIa inhibitors in ischemic stroke have been investigated, though cangrelor, a recent intravenous P2Y12-receptor inhibitor with a rapid onset/offset of action and a short half-life, may be a valuable option. We compared the safety and efficacy of cangrelor with those of glycoprotein IIb/IIIa inhibitors for refractory occlusions.

MATERIALS AND METHODS: We performed a retrospective analysis of the ongoing prospective, multicenter, observational Endovascular Treatment in Ischemic Stroke Registry in France between May 2012 and February 2020. Refractory intracranial occlusions of the anterior and posterior circulation were included and defined as recanalization failure of large-vessel occlusion stroke, perioperative target artery reocclusion, or high risk of early reocclusion related to an arterial wall lesion. The primary end point was a favorable outcome, defined as a 90-day mRS of 0–2. Secondary end points were reperfusion, intracranial hemorrhage, and procedural complications.

RESULTS: Among 69 patients, 15 were treated with cangrelor, and 54, with glycoprotein IIb/IIIa inhibitors. The favorable outcome (adjusted OR = 2.22; 95% CI, 0.42–11.75; P = .348) and mortality (adjusted OR = 0.44; 95% CI, 0.06–3.16; P = .411) rates were similar in both groups. There was no difference in the rates of any intracranial hemorrhage (adjusted OR = 0.40; 95% CI, 0.08–2.09; P = .280), symptomatic intracranial hemorrhage (6.7% versus 0.0%, P = .058), or procedural complications (6.7% versus 20.4%, P = .215). Reperfusion rates were higher in the cangrelor group, though the difference did not reach statistical significance (93.3% versus 75.0% for modified TICI 2b–3; adjusted OR =10.88; 95% CI, 0.96–123.84; P = .054).

CONCLUSIONS: Cangrelor seems to be as safe as glycoprotein IIb/IIIa inhibitors for managing refractory intracranial occlusion and leads to satisfactory brain reperfusion. Cangrelor is a promising agent in this setting, and additional studies are warranted to confirm our findings.

ASA
:   acetylsalicylic acid
GPIIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
mTICI
:   modified TICI
sICH
:   symptomatic intracranial hemorrhage" />
<meta name="og-title" property="og:title" content="A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/42/8/1452" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Rescue endovascular and pharmacologic approaches are increasingly being adopted after recanalization failure of acute large-vessel occlusion strokes with mechanical thrombectomy, with encouraging results. The safety and efficacy of glycoprotein IIb/IIIa inhibitors in ischemic stroke have been investigated, though cangrelor, a recent intravenous P2Y12-receptor inhibitor with a rapid onset/offset of action and a short half-life, may be a valuable option. We compared the safety and efficacy of cangrelor with those of glycoprotein IIb/IIIa inhibitors for refractory occlusions.

MATERIALS AND METHODS: We performed a retrospective analysis of the ongoing prospective, multicenter, observational Endovascular Treatment in Ischemic Stroke Registry in France between May 2012 and February 2020. Refractory intracranial occlusions of the anterior and posterior circulation were included and defined as recanalization failure of large-vessel occlusion stroke, perioperative target artery reocclusion, or high risk of early reocclusion related to an arterial wall lesion. The primary end point was a favorable outcome, defined as a 90-day mRS of 0–2. Secondary end points were reperfusion, intracranial hemorrhage, and procedural complications.

RESULTS: Among 69 patients, 15 were treated with cangrelor, and 54, with glycoprotein IIb/IIIa inhibitors. The favorable outcome (adjusted OR = 2.22; 95% CI, 0.42–11.75; P = .348) and mortality (adjusted OR = 0.44; 95% CI, 0.06–3.16; P = .411) rates were similar in both groups. There was no difference in the rates of any intracranial hemorrhage (adjusted OR = 0.40; 95% CI, 0.08–2.09; P = .280), symptomatic intracranial hemorrhage (6.7% versus 0.0%, P = .058), or procedural complications (6.7% versus 20.4%, P = .215). Reperfusion rates were higher in the cangrelor group, though the difference did not reach statistical significance (93.3% versus 75.0% for modified TICI 2b–3; adjusted OR =10.88; 95% CI, 0.96–123.84; P = .054).

CONCLUSIONS: Cangrelor seems to be as safe as glycoprotein IIb/IIIa inhibitors for managing refractory intracranial occlusion and leads to satisfactory brain reperfusion. Cangrelor is a promising agent in this setting, and additional studies are warranted to confirm our findings.

ASA
:   acetylsalicylic acid
GPIIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
mTICI
:   modified TICI
sICH
:   symptomatic intracranial hemorrhage" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node92366--7" data-node-nid="92366" id="top-node-92366--8946865898" data-pisa="ajnr;42/8/1452" data-pisa-master="ajnr;ajnr.A7180" data-apath="/ajnr/42/8/1452.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Interventional</span></span></div>
  
      <div class="highwire-cite-access"><span class="highwire-citation-access highwire-citation-access-check" data-pisa-id="ajnr;ajnr.A7180" data-atom-uri="/ajnr/42/8/1452.atom" data-request-view="full"></span></div>
  
      <h1 class="highwire-cite-title" id="page-title">A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">G. Marnat</span>, <span class="highwire-citation-author" data-delta="1">F. Delvoye</span>, <span class="highwire-citation-author" data-delta="2">S. Finitsis</span>, <span class="highwire-citation-author" data-delta="3">B. Lapergue</span>, <span class="highwire-citation-author" data-delta="4">F. Gariel</span>, <span class="highwire-citation-author" data-delta="5">A. Consoli</span>, <span class="highwire-citation-author" data-delta="6">J.-P. Desilles</span>, <span class="highwire-citation-author" data-delta="7">M. Mazighi</span>, <span class="highwire-citation-author" data-delta="8">C. Dargazanli</span>, <span class="highwire-citation-author" data-delta="9">R. Bourcier</span>, <span class="highwire-citation-author" data-delta="10">J. Darcourt</span>, <span class="highwire-citation-author" data-delta="11">V. Chalumeau</span>, <span class="highwire-citation-author" data-delta="12">M. Elhorany</span>, <span class="highwire-citation-author" data-delta="13">F. Clarençon</span>, <span class="highwire-citation-author" data-delta="14">S. Richard</span>, <span class="highwire-citation-author" data-delta="15">B. Gory</span>, <span class="highwire-citation-author" data-delta="16">I. Sibon</span> and <span class="highwire-citation-author" data-delta="17"><span class="nlm-collab" data-hwp-id="collab-1">on behalf of the ETIS Investigators</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">August 2021,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">42 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1452-1457; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A7180 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-92366--8946865898" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">G. Marnat </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Neuroradiology Department (G.M., F.G.) and Neurology (I.S.), Bordeaux University Hospital, Bordeaux, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G.%2BMarnat%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Marnat%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AG.%2BMarnat%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7611-7753" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for G. Marnat</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">F. Delvoye </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BDelvoye%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Delvoye%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BDelvoye%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0697-2156" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Delvoye</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">S. Finitsis </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Aristotle University of Thessaloniki (S.F.), Ahepa Hospital, Thessaloniki, Greece</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BFinitsis%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Finitsis%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BFinitsis%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-2140-7881" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. Finitsis</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">B. Lapergue </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>i</span>Department of Neurology (B.L.), Foch Hospital, Versailles Saint-Quentin-en-Yvelines University, Suresnes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BLapergue%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lapergue%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AB.%2BLapergue%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-8993-2175" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for B. Lapergue</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">F. Gariel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Neuroradiology Department (G.M., F.G.) and Neurology (I.S.), Bordeaux University Hospital, Bordeaux, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BGariel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gariel%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BGariel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-4636-2034" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Gariel</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">A. Consoli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Department s of Neuroradiology (A.C.) and Neurology (B.L.), Foch Hospital, Versailles Saint-Quentin en Yvelines University, Suresnes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BConsoli%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Consoli%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AA.%2BConsoli%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6640-8541" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for A. Consoli</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">J.-P. Desilles </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.-P.%2BDesilles%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Desilles%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.-P.%2BDesilles%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8395-6312" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.-P. Desilles</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">M. Mazighi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BMazighi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mazighi%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BMazighi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-0911-8999" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Mazighi</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">C. Dargazanli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>e</span>Department of Neuroradiology (C.D.), Centre Hospitalier Régional Universitaire Gui de Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BDargazanli%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Dargazanli%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BDargazanli%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-1891-9157" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Dargazanli</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">R. Bourcier </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>f</span>Department of Neuroradiology (R.B.), University Hospital of Nantes, Nantes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BBourcier%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bourcier%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AR.%2BBourcier%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6506-4019" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for R. Bourcier</a></li></ul></div><div class="author-tooltip-10"><div class="author-tooltip-name">J. Darcourt </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>g</span>Department of Neuroradiology (J.D.), University Hospital of Toulouse, Toulouse, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.%2BDarcourt%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Darcourt%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.%2BDarcourt%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-1620-4449" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J. Darcourt</a></li></ul></div><div class="author-tooltip-11"><div class="author-tooltip-name">V. Chalumeau </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>h</span>Department of Neuroradiology (M.E., F.C.), Pitié-Salpêtrière Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=V.%2BChalumeau%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chalumeau%20V&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AV.%2BChalumeau%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7753-7186" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for V. Chalumeau</a></li></ul></div><div class="author-tooltip-12"><div class="author-tooltip-name">M. Elhorany </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>h</span>Department of Neuroradiology (M.E., F.C.), Pitié-Salpêtrière Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BElhorany%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Elhorany%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BElhorany%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0257-2040" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Elhorany</a></li></ul></div><div class="author-tooltip-13"><div class="author-tooltip-name">F. Clarençon </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>h</span>Department of Neuroradiology (M.E., F.C.), Pitié-Salpêtrière Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BClaren%C3%A7on%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Claren%C3%A7on%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BClaren%25C3%25A7on%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6442-8239" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Clarençon</a></li></ul></div><div class="author-tooltip-14"><div class="author-tooltip-name">S. Richard </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>j</span>Department of Neurology (S.R.), Université de Lorraine, Centre Hospitalier Régional Universitaire-Nancy, Stroke Unit, Nancy, France</div><div class='author-affiliation'><span class='nlm-sup'>k</span>Institut national de la santé et de la recherche médicale U1116 (S.R.), Centre Hospitalier Régional Universitaire-Nancy, Nancy, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BRichard%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Richard%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BRichard%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0945-5656" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. Richard</a></li></ul></div><div class="author-tooltip-15"><div class="author-tooltip-name">B. Gory </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>l</span>Department of Diagnostic and Therapeutic Neuroradiology (B.G.), Université de Lorraine, CHRU-Nancy, Nancy, France .</div><div class='author-affiliation'><span class='nlm-sup'>m</span>Institut National de la Santé et de la Recherche Mmédicale U1254 (B.G.), Université de Lorraine, Imagerie Adaptative Diagnostique et Interventionnelle, Nancy, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BGory%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gory%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AB.%2BGory%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8424-4464" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for B. 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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div xmlns:xhtml="http://www.w3.org/1999/xhtml" class="contributors"><ol class="contributor-list" id="contrib-group-1"><li class="contributor" id="contrib-1"><span class="name">G. Marnat</span><a id="xref-aff-1-1" class="xref-aff" href="#aff-1">a</a>, </li><li class="contributor" id="contrib-2"><span class="name">F. Delvoye</span><a id="xref-aff-2-1" class="xref-aff" href="#aff-2">b</a>, </li><li class="contributor" id="contrib-3"><span class="name">S. Finitsis</span><a id="xref-aff-3-1" class="xref-aff" href="#aff-3">c</a>, </li><li class="contributor" id="contrib-4"><span class="name">B. Lapergue</span><a id="xref-aff-9-1" class="xref-aff" href="#aff-9">i</a>, </li><li class="contributor" id="contrib-5"><span class="name">F. Gariel</span><a id="xref-aff-1-2" class="xref-aff" href="#aff-1">a</a>, </li><li class="contributor" id="contrib-6"><span class="name">A. Consoli</span><a id="xref-aff-4-1" class="xref-aff" href="#aff-4">d</a>, </li><li class="contributor" id="contrib-7"><span class="name">J.-P. Desilles</span><a id="xref-aff-2-2" class="xref-aff" href="#aff-2">b</a>, </li><li class="contributor" id="contrib-8"><span class="name">M. Mazighi</span><a id="xref-aff-2-3" class="xref-aff" href="#aff-2">b</a>, </li><li class="contributor" id="contrib-9"><span class="name">C. Dargazanli</span><a id="xref-aff-5-1" class="xref-aff" href="#aff-5">e</a>, </li><li class="contributor" id="contrib-10"><span class="name">R. Bourcier</span><a id="xref-aff-6-1" class="xref-aff" href="#aff-6">f</a>, </li><li class="contributor" id="contrib-11"><span class="name">J. Darcourt</span><a id="xref-aff-7-1" class="xref-aff" href="#aff-7">g</a>, </li><li class="contributor" id="contrib-12"><span class="name">V. Chalumeau</span><a id="xref-aff-8-1" class="xref-aff" href="#aff-8">h</a>, </li><li class="contributor" id="contrib-13"><span class="name">M. Elhorany</span><a id="xref-aff-8-2" class="xref-aff" href="#aff-8">h</a>, </li><li class="contributor" id="contrib-14"><span class="name">F. Clarençon</span><a id="xref-aff-8-3" class="xref-aff" href="#aff-8">h</a>, </li><li class="contributor" id="contrib-15"><span class="name">S. Richard</span><a id="xref-aff-10-1" class="xref-aff" href="#aff-10">j</a><span class="xref-sep">,</span><a id="xref-aff-11-1" class="xref-aff" href="#aff-11">k</a>, </li><li class="contributor" id="contrib-16"><span class="name">B. Gory</span><a id="xref-aff-12-1" class="xref-aff" href="#aff-12">l</a><span class="xref-sep">,</span><a id="xref-aff-13-1" class="xref-aff" href="#aff-13">m</a>, </li><li class="contributor" id="contrib-17"><span class="name">I. Sibon</span>, </li><li class="last" id="contrib-18"><span class="collab" id="collab-1">on behalf of the ETIS Investigators</span></li></ol><ol class="affiliation-list"><li class="aff"><a id="aff-1" name="aff-1"></a><address><sup>a</sup>Neuroradiology Department (G.M., F.G.) and Neurology (I.S.), Bordeaux University Hospital, Bordeaux, France</address></li><li class="aff"><a id="aff-2" name="aff-2"></a><address><sup>b</sup>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</address></li><li class="aff"><a id="aff-3" name="aff-3"></a><address><sup>c</sup>Aristotle University of Thessaloniki (S.F.), Ahepa Hospital, Thessaloniki, Greece</address></li><li class="aff"><a id="aff-4" name="aff-4"></a><address><sup>d</sup>Department s of Neuroradiology (A.C.) and Neurology (B.L.), Foch Hospital, Versailles Saint-Quentin en Yvelines University, Suresnes, France</address></li><li class="aff"><a id="aff-5" name="aff-5"></a><address><sup>e</sup>Department of Neuroradiology (C.D.), Centre Hospitalier Régional Universitaire Gui de Chauliac, Montpellier, France</address></li><li class="aff"><a id="aff-6" name="aff-6"></a><address><sup>f</sup>Department of Neuroradiology (R.B.), University Hospital of Nantes, Nantes, France</address></li><li class="aff"><a id="aff-7" name="aff-7"></a><address><sup>g</sup>Department of Neuroradiology (J.D.), University Hospital of Toulouse, Toulouse, France</address></li><li class="aff"><a id="aff-8" name="aff-8"></a><address><sup>h</sup>Department of Neuroradiology (M.E., F.C.), Pitié-Salpêtrière Hospital, Paris, France</address></li><li class="aff"><a id="aff-9" name="aff-9"></a><address><sup>i</sup>Department of Neurology (B.L.), Foch Hospital, Versailles Saint-Quentin-en-Yvelines University, Suresnes, France</address></li><li class="aff"><a id="aff-10" name="aff-10"></a><address><sup>j</sup>Department of Neurology (S.R.), Université de Lorraine, Centre Hospitalier Régional Universitaire-Nancy, Stroke Unit, Nancy, France</address></li><li class="aff"><a id="aff-11" name="aff-11"></a><address><sup>k</sup>Institut national de la santé et de la recherche médicale U1116 (S.R.), Centre Hospitalier Régional Universitaire-Nancy, Nancy, France</address></li><li class="aff"><a id="aff-12" name="aff-12"></a><address><sup>l</sup>Department of Diagnostic and Therapeutic Neuroradiology (B.G.), Université de Lorraine, CHRU-Nancy, Nancy, France .</address></li><li class="aff"><a id="aff-13" name="aff-13"></a><address><sup>m</sup>Institut National de la Santé et de la Recherche Mmédicale U1254 (B.G.), Université de Lorraine, Imagerie Adaptative Diagnostique et Interventionnelle, Nancy, France</address></li></ol><ol class="corresp-list"><li class="corresp" id="corresp-1">Please address correspondence to Gaultier Marnat, MD, <span class="addr-line">Department of Neuroradiology, Bordeaux University Hospital, Place Amélie Raba-Léon, 33000 Bordeaux, France</span>; e-mail: <span class="em-link"><span class="em-addr">gaultier.marnat{at}chu-bordeaux.fr</span></span></li></ol></div></div><a href="http://ajnr-stage2.stage.highwire.org/content/42/8/1452.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 42</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 8 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Aug 2021 </div></div>
      
      
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      <div class="highwire-cite-title">A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Marnat</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Delvoye</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Finitsis</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Lapergue</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Gariel</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Consoli</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">J.-P.</span> <span class="nlm-surname">Desilles</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Mazighi</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Dargazanli</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Bourcier</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Darcourt</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Chalumeau</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Elhorany</span></span>, <span class="highwire-citation-author" data-delta="13"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Clarençon</span></span>, <span class="highwire-citation-author" data-delta="14"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Richard</span></span>, <span class="highwire-citation-author" data-delta="15"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Gory</span></span>, <span class="highwire-citation-author" data-delta="16"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Sibon</span></span>, <span class="highwire-citation-author" data-delta="17"><span class="nlm-collab" data-hwp-id="collab-1">on behalf of the ETIS Investigators</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2021, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">42 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1452-1457; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7180 </span></div>
  
  
  
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      <div class="highwire-cite-title">A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Marnat</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Delvoye</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Finitsis</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Lapergue</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Gariel</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Consoli</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">J.-P.</span> <span class="nlm-surname">Desilles</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Mazighi</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Dargazanli</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Bourcier</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Darcourt</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Chalumeau</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Elhorany</span></span>, <span class="highwire-citation-author" data-delta="13"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Clarençon</span></span>, <span class="highwire-citation-author" data-delta="14"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Richard</span></span>, <span class="highwire-citation-author" data-delta="15"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Gory</span></span>, <span class="highwire-citation-author" data-delta="16"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Sibon</span></span>, <span class="highwire-citation-author" data-delta="17"><span class="nlm-collab" data-hwp-id="collab-1">on behalf of the ETIS Investigators</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2021, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">42 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(8) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1452-1457; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7180 </span></div>
  
  
  
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