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<meta name="DC.Title" content="Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis" />
<meta name="DC.Identifier" content="10.3174/ajnr.A7430" />
<meta name="DC.Date" content="2022-03-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Rescue therapies are increasingly used in the setting of endovascular therapy for large-vessel occlusion strokes. Among these, cangrelor, a new P2Y12 inhibitor, offers promising pharmacologic properties to join the reperfusion strategies in acute stroke. We assessed the safety and efficacy profiles of cangrelor combined with endovascular therapy in patients with large-vessel-occlusion stroke.

MATERIALS AND METHODS: We performed a retrospective patient data analysis in the ongoing prospective multicenter observational Endovascular Treatment in Ischemic Stroke Registry in France from July 2018 to December 2020 and conducted a systematic review and meta-analysis using several data bases. Indications for cangrelor administration were rescue strategy in case of refractory intracranial occlusion with or without intracranial rescue stent placement, and cervical carotid artery stent placement in case of cervical occlusion (tandem occlusion or isolated cervical carotid occlusion).

RESULTS: In the clinical registry, 44 patients were included (median initial NIHSS score, 12; prior intravenous thrombolysis, 29.5%). Intracranial stent placement was performed in 54.5% ( n  = 24/44), and cervical stent placement, in 27.3% ( n  = 12/44). Adjunctive aspirin and heparin were administered in 75% ( n  = 33/44) and 40.9% ( n  = 18/44), respectively. Rates of symptomatic intracerebral hemorrhage, parenchymal hematoma, and 90-day mortality were 9.5% ( n  = 4/42), 9.5% ( n  = 4/42), and 24.4% ( n  = 10/41). Favorable outcome (90-day mRS, 0–2) was reached in 51.2% ( n  = 21/41), and successful reperfusion, in 90.9% ( n  = 40/44). The literature search identified 6 studies involving a total of 171 subjects. In the meta-analysis, including our series data, symptomatic intracerebral hemorrhage occurred in 8.6% of patients (95% CI, 5.0%–14.3%) and favorable outcome was reached in 47.6% of patients (95% CI, 27.4%–68.7%). The 90-day mortality rate was 22.6% (95% CI, 13.6%–35.2%). Day 1 artery patency was observed in 89.7% (95% CI, 81.4%–94.6%).

CONCLUSIONS: Cangrelor offers promising safety and efficacy profiles, especially considering the complex endovascular reperfusion procedures in which it is usually applied. Further large prospective data are required to confirm these findings.

ETIS
:   Endovascular Treatment in Ischemic Stroke
EVT
:   endovascular therapy
GP IIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
IQR
:   interquartile range
IVT
:   intravenous thrombolysis
LVOS
:   large-vessel-occlusion stroke
sICH
:   symptomatic intracranial hemorrhage" />
<meta name="DC.Contributor" content="G. Marnat" />
<meta name="DC.Contributor" content="S. Finistis" />
<meta name="DC.Contributor" content="F. Delvoye" />
<meta name="DC.Contributor" content="I. Sibon" />
<meta name="DC.Contributor" content="J.-P. Desilles" />
<meta name="DC.Contributor" content="M. Mazighi" />
<meta name="DC.Contributor" content="F. Gariel" />
<meta name="DC.Contributor" content="A. Consoli" />
<meta name="DC.Contributor" content="C. Rosso" />
<meta name="DC.Contributor" content="F. Clarençon" />
<meta name="DC.Contributor" content="M. Elhorany" />
<meta name="DC.Contributor" content="C. Denier" />
<meta name="DC.Contributor" content="V. Chalumeau" />
<meta name="DC.Contributor" content="J. Caroff" />
<meta name="DC.Contributor" content="L. Veunac" />
<meta name="DC.Contributor" content="F. Bourdain" />
<meta name="DC.Contributor" content="J. Darcourt" />
<meta name="DC.Contributor" content="J.-M. Olivot" />
<meta name="DC.Contributor" content="R. Bourcier" />
<meta name="DC.Contributor" content="C. Dargazanli" />
<meta name="DC.Contributor" content="C. Arquizan" />
<meta name="DC.Contributor" content="S. Richard" />
<meta name="DC.Contributor" content="B. Lapergue" />
<meta name="DC.Contributor" content="B. Gory" />
<meta name="article:published_time" content="2022-03-01" />
<meta name="article:section" content="Interventional" />
<meta name="citation_title" content="Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Rescue therapies are increasingly used in the setting of endovascular therapy for large-vessel occlusion strokes. Among these, cangrelor, a new P2Y12 inhibitor, offers promising pharmacologic properties to join the reperfusion strategies in acute stroke. We assessed the safety and efficacy profiles of cangrelor combined with endovascular therapy in patients with large-vessel-occlusion stroke.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;We performed a retrospective patient data analysis in the ongoing prospective multicenter observational Endovascular Treatment in Ischemic Stroke Registry in France from July 2018 to December 2020 and conducted a systematic review and meta-analysis using several data bases. Indications for cangrelor administration were rescue strategy in case of refractory intracranial occlusion with or without intracranial rescue stent placement, and cervical carotid artery stent placement in case of cervical occlusion (tandem occlusion or isolated cervical carotid occlusion).&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;In the clinical registry, 44 patients were included (median initial NIHSS score, 12; prior intravenous thrombolysis, 29.5%). Intracranial stent placement was performed in 54.5% (&lt;i&gt;n&lt;/i&gt; = 24/44), and cervical stent placement, in 27.3% (&lt;i&gt;n&lt;/i&gt; = 12/44). Adjunctive aspirin and heparin were administered in 75% (&lt;i&gt;n&lt;/i&gt; = 33/44) and 40.9% (&lt;i&gt;n&lt;/i&gt; = 18/44), respectively. Rates of symptomatic intracerebral hemorrhage, parenchymal hematoma, and 90-day mortality were 9.5% (&lt;i&gt;n&lt;/i&gt; = 4/42), 9.5% (&lt;i&gt;n&lt;/i&gt; = 4/42), and 24.4% (&lt;i&gt;n&lt;/i&gt; = 10/41). Favorable outcome (90-day mRS, 0–2) was reached in 51.2% (&lt;i&gt;n&lt;/i&gt; = 21/41), and successful reperfusion, in 90.9% (&lt;i&gt;n&lt;/i&gt; = 40/44). The literature search identified 6 studies involving a total of 171 subjects. In the meta-analysis, including our series data, symptomatic intracerebral hemorrhage occurred in 8.6% of patients (95% CI, 5.0%–14.3%) and favorable outcome was reached in 47.6% of patients (95% CI, 27.4%–68.7%). The 90-day mortality rate was 22.6% (95% CI, 13.6%–35.2%). Day 1 artery patency was observed in 89.7% (95% CI, 81.4%–94.6%).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Cangrelor offers promising safety and efficacy profiles, especially considering the complex endovascular reperfusion procedures in which it is usually applied. Further large prospective data are required to confirm these findings.&lt;/p&gt;" />
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<meta name="twitter:title" content="Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis" />
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<meta name="twitter:image" content="http://ajnr-stage2.stage.highwire.org/sites/default/files/highwire/ajnr/43/3.cover-source.jpg" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Rescue therapies are increasingly used in the setting of endovascular therapy for large-vessel occlusion strokes. Among these, cangrelor, a new P2Y12 inhibitor, offers promising pharmacologic properties to join the reperfusion strategies in acute stroke. We assessed the safety and efficacy profiles of cangrelor combined with endovascular therapy in patients with large-vessel-occlusion stroke.

MATERIALS AND METHODS: We performed a retrospective patient data analysis in the ongoing prospective multicenter observational Endovascular Treatment in Ischemic Stroke Registry in France from July 2018 to December 2020 and conducted a systematic review and meta-analysis using several data bases. Indications for cangrelor administration were rescue strategy in case of refractory intracranial occlusion with or without intracranial rescue stent placement, and cervical carotid artery stent placement in case of cervical occlusion (tandem occlusion or isolated cervical carotid occlusion).

RESULTS: In the clinical registry, 44 patients were included (median initial NIHSS score, 12; prior intravenous thrombolysis, 29.5%). Intracranial stent placement was performed in 54.5% ( n  = 24/44), and cervical stent placement, in 27.3% ( n  = 12/44). Adjunctive aspirin and heparin were administered in 75% ( n  = 33/44) and 40.9% ( n  = 18/44), respectively. Rates of symptomatic intracerebral hemorrhage, parenchymal hematoma, and 90-day mortality were 9.5% ( n  = 4/42), 9.5% ( n  = 4/42), and 24.4% ( n  = 10/41). Favorable outcome (90-day mRS, 0–2) was reached in 51.2% ( n  = 21/41), and successful reperfusion, in 90.9% ( n  = 40/44). The literature search identified 6 studies involving a total of 171 subjects. In the meta-analysis, including our series data, symptomatic intracerebral hemorrhage occurred in 8.6% of patients (95% CI, 5.0%–14.3%) and favorable outcome was reached in 47.6% of patients (95% CI, 27.4%–68.7%). The 90-day mortality rate was 22.6% (95% CI, 13.6%–35.2%). Day 1 artery patency was observed in 89.7% (95% CI, 81.4%–94.6%).

CONCLUSIONS: Cangrelor offers promising safety and efficacy profiles, especially considering the complex endovascular reperfusion procedures in which it is usually applied. Further large prospective data are required to confirm these findings.

ETIS
:   Endovascular Treatment in Ischemic Stroke
EVT
:   endovascular therapy
GP IIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
IQR
:   interquartile range
IVT
:   intravenous thrombolysis
LVOS
:   large-vessel-occlusion stroke
sICH
:   symptomatic intracranial hemorrhage" />
<meta name="og-title" property="og:title" content="Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/43/3/410" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Rescue therapies are increasingly used in the setting of endovascular therapy for large-vessel occlusion strokes. Among these, cangrelor, a new P2Y12 inhibitor, offers promising pharmacologic properties to join the reperfusion strategies in acute stroke. We assessed the safety and efficacy profiles of cangrelor combined with endovascular therapy in patients with large-vessel-occlusion stroke.

MATERIALS AND METHODS: We performed a retrospective patient data analysis in the ongoing prospective multicenter observational Endovascular Treatment in Ischemic Stroke Registry in France from July 2018 to December 2020 and conducted a systematic review and meta-analysis using several data bases. Indications for cangrelor administration were rescue strategy in case of refractory intracranial occlusion with or without intracranial rescue stent placement, and cervical carotid artery stent placement in case of cervical occlusion (tandem occlusion or isolated cervical carotid occlusion).

RESULTS: In the clinical registry, 44 patients were included (median initial NIHSS score, 12; prior intravenous thrombolysis, 29.5%). Intracranial stent placement was performed in 54.5% ( n  = 24/44), and cervical stent placement, in 27.3% ( n  = 12/44). Adjunctive aspirin and heparin were administered in 75% ( n  = 33/44) and 40.9% ( n  = 18/44), respectively. Rates of symptomatic intracerebral hemorrhage, parenchymal hematoma, and 90-day mortality were 9.5% ( n  = 4/42), 9.5% ( n  = 4/42), and 24.4% ( n  = 10/41). Favorable outcome (90-day mRS, 0–2) was reached in 51.2% ( n  = 21/41), and successful reperfusion, in 90.9% ( n  = 40/44). The literature search identified 6 studies involving a total of 171 subjects. In the meta-analysis, including our series data, symptomatic intracerebral hemorrhage occurred in 8.6% of patients (95% CI, 5.0%–14.3%) and favorable outcome was reached in 47.6% of patients (95% CI, 27.4%–68.7%). The 90-day mortality rate was 22.6% (95% CI, 13.6%–35.2%). Day 1 artery patency was observed in 89.7% (95% CI, 81.4%–94.6%).

CONCLUSIONS: Cangrelor offers promising safety and efficacy profiles, especially considering the complex endovascular reperfusion procedures in which it is usually applied. Further large prospective data are required to confirm these findings.

ETIS
:   Endovascular Treatment in Ischemic Stroke
EVT
:   endovascular therapy
GP IIb/IIIa
:   glycoprotein IIb/IIIa
ICH
:   intracranial hemorrhage
IQR
:   interquartile range
IVT
:   intravenous thrombolysis
LVOS
:   large-vessel-occlusion stroke
sICH
:   symptomatic intracranial hemorrhage" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node96089--5" data-node-nid="96089" id="top-node-96089--6127299817" data-pisa="ajnr;43/3/410" data-pisa-master="ajnr;ajnr.A7430" data-apath="/ajnr/43/3/410.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Interventional</span></span></div>
  
      <div class="highwire-cite-access"><span class="highwire-citation-access highwire-citation-access-check" data-pisa-id="ajnr;ajnr.A7430" data-atom-uri="/ajnr/43/3/410.atom" data-request-view="full"></span></div>
  
      <h1 class="highwire-cite-title" id="page-title">Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">G. Marnat</span>, <span class="highwire-citation-author" data-delta="1">S. Finistis</span>, <span class="highwire-citation-author" data-delta="2">F. Delvoye</span>, <span class="highwire-citation-author" data-delta="3">I. Sibon</span>, <span class="highwire-citation-author" data-delta="4">J.-P. Desilles</span>, <span class="highwire-citation-author" data-delta="5">M. Mazighi</span>, <span class="highwire-citation-author" data-delta="6">F. Gariel</span>, <span class="highwire-citation-author" data-delta="7">A. Consoli</span>, <span class="highwire-citation-author" data-delta="8">C. Rosso</span>, <span class="highwire-citation-author" data-delta="9">F. Clarençon</span>, <span class="highwire-citation-author" data-delta="10">M. Elhorany</span>, <span class="highwire-citation-author" data-delta="11">C. Denier</span>, <span class="highwire-citation-author" data-delta="12">V. Chalumeau</span>, <span class="highwire-citation-author" data-delta="13">J. Caroff</span>, <span class="highwire-citation-author" data-delta="14">L. Veunac</span>, <span class="highwire-citation-author" data-delta="15">F. Bourdain</span>, <span class="highwire-citation-author" data-delta="16">J. Darcourt</span>, <span class="highwire-citation-author" data-delta="17">J.-M. Olivot</span>, <span class="highwire-citation-author" data-delta="18">R. Bourcier</span>, <span class="highwire-citation-author" data-delta="19">C. Dargazanli</span>, <span class="highwire-citation-author" data-delta="20">C. Arquizan</span>, <span class="highwire-citation-author" data-delta="21">S. Richard</span>, <span class="highwire-citation-author" data-delta="22">B. Lapergue</span> and <span class="highwire-citation-author" data-delta="23">B. Gory</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">March 2022,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">410-415; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A7430 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-96089--6127299817" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">G. Marnat </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), University Hospital of Bordeaux, Bordeaux, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G.%2BMarnat%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Marnat%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AG.%2BMarnat%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7611-7753" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for G. Marnat</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">S. Finistis </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Aristotle University of Thessaloniki (S.F.), AhepaHospital, Thessaloniki, Greece</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BFinistis%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Finistis%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BFinistis%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-2140-7881" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. Finistis</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">F. Delvoye </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BDelvoye%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Delvoye%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BDelvoye%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0697-2156" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Delvoye</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">I. Sibon </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Neurology (I.S.), Stroke Center, University Hospital of Bordeaux, Bordeaux, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=I.%2BSibon%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sibon%20I&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AI.%2BSibon%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-1171-4215" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for I. Sibon</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">J.-P. Desilles </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.-P.%2BDesilles%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Desilles%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.-P.%2BDesilles%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8395-6312" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.-P. Desilles</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">M. Mazighi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Interventional Neuroradiology (F.D., J.-P.D., M.M.), Rothschild Foundation, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BMazighi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mazighi%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BMazighi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-0911-8999" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Mazighi</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">F. Gariel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Diagnostic and Interventional Neuroradiology (G.M., F.G.), University Hospital of Bordeaux, Bordeaux, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BGariel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gariel%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BGariel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-4636-2034" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Gariel</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">A. Consoli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>e</span>Department of Diagnostic and Interventional Neuroradiology (A.C.), Foch Hospital, Versailles Saint-Quentin en Yvelines University, Suresnes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BConsoli%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Consoli%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AA.%2BConsoli%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-6640-8541" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for A. Consoli</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">C. Rosso </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>f</span>Department of Neurology (C.R.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BRosso%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Rosso%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BRosso%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-7236-1508" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Rosso</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">F. Clarençon </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>g</span>Neuroradiology (F.C., M.E.), Centre Hospitalier Universitaire Pitié Salpétrière Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BClaren%C3%A7on%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Claren%C3%A7on%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BClaren%25C3%25A7on%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6442-8239" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Clarençon</a></li></ul></div><div class="author-tooltip-10"><div class="author-tooltip-name">M. Elhorany </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>g</span>Neuroradiology (F.C., M.E.), Centre Hospitalier Universitaire Pitié Salpétrière Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BElhorany%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Elhorany%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BElhorany%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0257-2040" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Elhorany</a></li></ul></div><div class="author-tooltip-11"><div class="author-tooltip-name">C. Denier </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>h</span>Department of Neurology (C. Denier)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BDenier%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Denier%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BDenier%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-2087-5563" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Denier</a></li></ul></div><div class="author-tooltip-12"><div class="author-tooltip-name">V. Chalumeau </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>i</span>Neuroradiolology (V.C., J.C.) Centre Hospitalier Universitaire Kremlin Bicêtre, Le Kremlin Bicêtre, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=V.%2BChalumeau%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chalumeau%20V&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AV.%2BChalumeau%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7753-7186" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for V. Chalumeau</a></li></ul></div><div class="author-tooltip-13"><div class="author-tooltip-name">J. Caroff </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>i</span>Neuroradiolology (V.C., J.C.) Centre Hospitalier Universitaire Kremlin Bicêtre, Le Kremlin Bicêtre, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.%2BCaroff%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Caroff%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.%2BCaroff%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0029-1835" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J. Caroff</a></li></ul></div><div class="author-tooltip-14"><div class="author-tooltip-name">L. Veunac </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>k</span>Neuroradiolology (L.V.), Centre Hospitalier Cõte Basque, Bayonne, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=L.%2BVeunac%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Veunac%20L&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AL.%2BVeunac%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-7837-3929" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for L. Veunac</a></li></ul></div><div class="author-tooltip-15"><div class="author-tooltip-name">F. Bourdain </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>j</span>Department of Neurology (F.B.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.%2BBourdain%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bourdain%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.%2BBourdain%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0757-1346" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F. Bourdain</a></li></ul></div><div class="author-tooltip-16"><div class="author-tooltip-name">J. Darcourt </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>m</span>Neuroradiolology (J.D.), Centre Hospitalier Universitaire de Toulouse, Toulouse, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.%2BDarcourt%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Darcourt%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.%2BDarcourt%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-1620-4449" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J. Darcourt</a></li></ul></div><div class="author-tooltip-17"><div class="author-tooltip-name">J.-M. Olivot </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>l</span>Departments of Neurology (J.-M.O.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.-M.%2BOlivot%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Olivot%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.-M.%2BOlivot%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-2027-2276" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.-M. 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Bourcier </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>n</span>Department of Neuroradiology (R.B.), University Hospital of Nantes, Nantes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BBourcier%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bourcier%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AR.%2BBourcier%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6506-4019" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for R. Bourcier</a></li></ul></div><div class="author-tooltip-19"><div class="author-tooltip-name">C. Dargazanli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>o</span>Departments of Interventional Neuroradiology (C. 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Arquizan </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>p</span>Neurology (C.A.), Centre Hospitalier Regional Universitaire Gui de Chauliac, Montpellier, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BArquizan%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Arquizan%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BArquizan%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-7347-1039" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. 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Richard </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>q</span>Department of Neurology (S.R.), Université de Lorraine, Centre Hospitalier Regional Universitaire Nancy, Nancy, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BRichard%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Richard%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BRichard%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0945-5656" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. 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Lapergue </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>r</span>Department of Neurology (B.L.), Foch Hospital, Versailles Saint-Quentin en Yvelines University, Suresnes, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BLapergue%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lapergue%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AB.%2BLapergue%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-8993-2175" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for B. 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Gory </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>s</span>Department of Diagnostic and Therapeutic Neuroradiology (B.G.), Université de Lorraine, Centre Hospitalier Regional Universitaire Nancy, Nancy, France</div><div class='author-affiliation'><span class='nlm-sup'>t</span>Université de Lorraine (B.G.), Imagerie Adaptative Diagnostique et Interventionnelle, Institut National de la Santé et de la Recherche Médicale U1254, Nancy, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BGory%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gory%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AB.%2BGory%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8424-4464" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for B. 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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" xmlns:xhtml="http://www.w3.org/1999/xhtml" class="section ref-list" id="ref-list-1"><h2 class="">References</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1. in text" id="ref-1">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.1" data-doi="10.1016/S0140-6736(16)00163-X"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Goyal</span>  <span class="cit-name-given-names">M</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Menon</span>  <span class="cit-name-given-names">BK</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Van Zwam</span>  <span class="cit-name-given-names">WH</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials</span>. <abbr class="cit-jnl-abbrev">Lancet</abbr> <span class="cit-pub-date">2016</span>;<span class="cit-vol">387</span>:<span class="cit-fpage">1723</span>–<span class="cit-lpage">31</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/S0140-6736(16)00163-X</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>26898852</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/S0140-6736(16)00163-X&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=26898852&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">2.</span><a class="rev-xref-ref" href="#xref-ref-2-1" title="View reference 2. in text" id="ref-2">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.2" data-doi="10.1161/STROKEAHA.116.014073"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Baek</span>  <span class="cit-name-given-names">JH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kim</span>  <span class="cit-name-given-names">BM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kim</span>  <span class="cit-name-given-names">DJ</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Stenting as a rescue treatment after failure of mechanical thrombectomy for anterior circulation large artery occlusion</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2016</span>;<span class="cit-vol">47</span>:<span class="cit-fpage">2360</span>–<span class="cit-lpage">63</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.116.014073</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>27444259</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToic3Ryb2tlYWhhIjtzOjU6InJlc2lkIjtzOjk6IjQ3LzkvMjM2MCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci80My8zLzQxMC5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">3.</span><a class="rev-xref-ref" href="#xref-ref-3-1" title="View reference 3. in text" id="ref-3">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.3" data-doi="10.1136/neurintsurg-2017-013489"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Jia</span>  <span class="cit-name-given-names">B</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Feng</span>  <span class="cit-name-given-names">L</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Liebeskind</span>  <span class="cit-name-given-names">DS</span></span>, <span class="cit-etal">et al</span></li></ol><cite>; <span class="cit-auth cit-collab">EAST Study Group</span>. <span class="cit-article-title">Mechanical thrombectomy and rescue therapy for intracranial large artery occlusion with underlying atherosclerosis</span>. <abbr class="cit-jnl-abbrev">J Neurointerv Surg</abbr> <span class="cit-pub-date">2018</span>;<span class="cit-vol">10</span>:<span class="cit-fpage">746</span>–<span class="cit-lpage">50</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1136/neurintsurg-2017-013489</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>29203731</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6MTE6Im5ldXJpbnRzdXJnIjtzOjU6InJlc2lkIjtzOjg6IjEwLzgvNzQ2IjtzOjQ6ImF0b20iO3M6MTk6Ii9ham5yLzQzLzMvNDEwLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">4.</span><a class="rev-xref-ref" href="#xref-ref-4-1" title="View reference 4. in text" id="ref-4">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.4" data-doi="10.1161/STROKEAHA.120.029994"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Yang</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Wu</span>  <span class="cit-name-given-names">Y</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Gao</span>  <span class="cit-name-given-names">X</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Intraarterial versus intravenous tirofiban as an adjunct to endovascular thrombectomy for acute ischemic stroke</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">51</span>:<span class="cit-fpage">2925</span>–<span class="cit-lpage">33</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.120.029994</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>32933416</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1161/STROKEAHA.120.029994&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=32933416&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">5.</span><a class="rev-xref-ref" href="#xref-ref-5-1" title="View reference 5. in text" id="ref-5">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.5" data-doi="10.1007/s00234-020-02360-9"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Premat</span>  <span class="cit-name-given-names">K</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dechartres</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Lenck</span>  <span class="cit-name-given-names">S</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Rescue stenting versus medical care alone in refractory large vessel occlusions: a systematic review and meta-analysis</span>. <abbr class="cit-jnl-abbrev">Neuroradiology</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">62</span>:<span class="cit-fpage">629</span>–<span class="cit-lpage">37</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1007/s00234-020-02360-9</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31927615</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00234-020-02360-9&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31927615&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">6.</span><a class="rev-xref-ref" href="#xref-ref-6-1" title="View reference 6. in text" id="ref-6">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.6" data-doi="10.1161/STROKEAHA.117.020072"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Chang</span>  <span class="cit-name-given-names">Y</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kim</span>  <span class="cit-name-given-names">BM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Bang</span>  <span class="cit-name-given-names">OY</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Rescue stenting for failed mechanical thrombectomy in acute ischemic stroke: a multicenter experience</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2018</span>;<span class="cit-vol">49</span>:<span class="cit-fpage">958</span>–<span class="cit-lpage">64</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.117.020072</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>29581342</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToic3Ryb2tlYWhhIjtzOjU6InJlc2lkIjtzOjg6IjQ5LzQvOTU4IjtzOjQ6ImF0b20iO3M6MTk6Ii9ham5yLzQzLzMvNDEwLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">7.</span><a class="rev-xref-ref" href="#xref-ref-7-1" title="View reference 7. in text" id="ref-7">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.7" data-doi="10.1136/neurintsurg-2019-015154"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Peng</span>  <span class="cit-name-given-names">F</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Wan</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Liu</span>  <span class="cit-name-given-names">W</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Efficacy and safety of rescue stenting following failed mechanical thrombectomy for anterior circulation large vessel occlusion: propensity score analysis</span>. <abbr class="cit-jnl-abbrev">J Neurointerv Surg</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">12</span>:<span class="cit-fpage">271</span>–<span class="cit-lpage">73</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1136/neurintsurg-2019-015154</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31530654</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6MTE6Im5ldXJpbnRzdXJnIjtzOjU6InJlc2lkIjtzOjg6IjEyLzMvMjcxIjtzOjQ6ImF0b20iO3M6MTk6Ii9ham5yLzQzLzMvNDEwLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">8.</span><a class="rev-xref-ref" href="#xref-ref-8-1" title="View reference 8. in text" id="ref-8">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.8" data-doi="10.1136/neurintsurg-2020-015841"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Linfante</span>  <span class="cit-name-given-names">I</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ravipati</span>  <span class="cit-name-given-names">K</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Starosciak</span>  <span class="cit-name-given-names">AK</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Intravenous cangrelor and oral ticagrelor as an alternative to clopidogrel in acute intervention</span>. <abbr class="cit-jnl-abbrev">J Neurointerv Surg</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">13</span>:<span class="cit-fpage">30</span>–<span class="cit-lpage">32</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1136/neurintsurg-2020-015841</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>32414891</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6MTE6Im5ldXJpbnRzdXJnIjtzOjU6InJlc2lkIjtzOjc6IjEzLzEvMzAiO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvNDMvMy80MTAuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">9.</span><a class="rev-xref-ref" href="#xref-ref-9-1" title="View reference 9. in text" id="ref-9">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.9" data-doi="10.3174/ajnr.A6785"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Cervo</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Ferrari</span>  <span class="cit-name-given-names">F</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Barchetti</span>  <span class="cit-name-given-names">G</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Use of cangrelor in cervical and intracranial stenting for the treatment of acute ischemic stroke: a “real life” single-center experience</span>. <abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">41</span>:<span class="cit-fpage">2094</span>–<span class="cit-lpage">99</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3174/ajnr.A6785</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>33033047</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czoxMDoiNDEvMTEvMjA5NCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci80My8zLzQxMC5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">10.</span><a class="rev-xref-ref" href="#xref-ref-10-1" title="View reference 10. in text" id="ref-10">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.10" data-doi="10.1007/s00062-020-00907-0"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Elhorany</span>  <span class="cit-name-given-names">M</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Lenck</span>  <span class="cit-name-given-names">S</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Degos</span>  <span class="cit-name-given-names">V</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Cangrelor and stenting in acute ischemic stroke: monocentric case series</span>. <abbr class="cit-jnl-abbrev">Clin Neuroradiol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">31</span>:<span class="cit-fpage">439</span>–<span class="cit-lpage">48</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1007/s00062-020-00907-0</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>32382875</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00062-020-00907-0&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=32382875&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">11.</span><a class="rev-xref-ref" href="#xref-ref-11-1" title="View reference 11. in text" id="ref-11">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.11" data-doi="10.1177/1591019920936923"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Entezami</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Holden</span>  <span class="cit-name-given-names">DN</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Boulos</span>  <span class="cit-name-given-names">AS</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Cangrelor dose titration using platelet function testing during cerebrovascular stent placement</span>. <abbr class="cit-jnl-abbrev">Interv Neuroradiol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">27</span>:<span class="cit-fpage">88</span>–<span class="cit-lpage">98</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1177/1591019920936923</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>32611215</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1177/1591019920936923&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=32611215&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">12.</span><a class="rev-xref-ref" href="#xref-ref-12-1" title="View reference 12. in text" id="ref-12">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.12" data-doi="10.1136/neurintsurg-2018-014396"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Aguilar-Salinas</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Agnoletto</span>  <span class="cit-name-given-names">GJ</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Brasiliense</span>  <span class="cit-name-given-names">LB</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Safety and efficacy of cangrelor in acute stenting for the treatment of cerebrovascular pathology: preliminary experience in a single-center pilot study</span>. <abbr class="cit-jnl-abbrev">J Neuronterv Surg</abbr> <span class="cit-pub-date">2019</span>;<span class="cit-vol">11</span>:<span class="cit-fpage">347</span>–<span class="cit-lpage">51</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1136/neurintsurg-2018-014396</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>30552167</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6MTE6Im5ldXJpbnRzdXJnIjtzOjU6InJlc2lkIjtzOjg6IjExLzQvMzQ3IjtzOjQ6ImF0b20iO3M6MTk6Ii9ham5yLzQzLzMvNDEwLmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ==" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">13.</span><a class="rev-xref-ref" href="#xref-ref-13-1" title="View reference 13. in text" id="ref-13">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.13" data-doi="10.1007/s00062-019-00811-2"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Abdennour</span>  <span class="cit-name-given-names">L</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Sourour</span>  <span class="cit-name-given-names">N</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Drir</span>  <span class="cit-name-given-names">M</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Preliminary experience with cangrelor for endovascular treatment of challenging intracranial aneurysms</span>. <abbr class="cit-jnl-abbrev">Clin Neuroradiol</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">30</span>:<span class="cit-fpage">453</span>–<span class="cit-lpage">61</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1007/s00062-019-00811-2</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31309241</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00062-019-00811-2&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31309241&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">14.</span><a class="rev-xref-ref" href="#xref-ref-14-1" title="View reference 14. in text" id="ref-14">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.14" data-doi="10.1007/s00234-020-02599-2"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Cortez</span>  <span class="cit-name-given-names">GM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Monteiro</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Sourour</span>  <span class="cit-name-given-names">N</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">The use of cangrelor in neurovascular interventions: a multicenter experience</span>. <abbr class="cit-jnl-abbrev">Neuroradiology</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">63</span>:<span class="cit-fpage">925</span>–<span class="cit-lpage">34</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1007/s00234-020-02599-2</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>33174182</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00234-020-02599-2&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=33174182&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">15.</span><a class="rev-xref-ref" href="#xref-ref-15-1" title="View reference 15. in text" id="ref-15">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.15" data-doi="10.1177/15910199211014417"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Paul</span>  <span class="cit-name-given-names">AR</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Entezami</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Holden</span>  <span class="cit-name-given-names">D</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Use of intravenous cangrelor and stenting in acute ischemic stroke interventions: a new single center analysis and pooled-analysis of current studies</span>. <abbr class="cit-jnl-abbrev">Interv Neuroradiol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">27</span>:<span class="cit-fpage">837</span>–<span class="cit-lpage">42</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1177/15910199211014417</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>33945341</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1177/15910199211014417&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=33945341&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">16.</span><a class="rev-xref-ref" href="#xref-ref-16-1" title="View reference 16. in text" id="ref-16">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.16" data-doi="10.3389/fneur.2021.636682"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Salahuddin</span>  <span class="cit-name-given-names">H</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dawod</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Zaidi</span>  <span class="cit-name-given-names">SF</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Safety of low dose intravenous cangrelor in acute ischemic stroke: a case series</span>. <abbr class="cit-jnl-abbrev">Front Neurol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">12</span>:<span class="cit-fpage">636682</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3389/fneur.2021.636682</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>34149590</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.3389/fneur.2021.636682&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=34149590&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">17.</span><a class="rev-xref-ref" href="#xref-ref-17-1" title="View reference 17. in text" id="ref-17">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.17" data-doi="10.1097/CRD.0000000000000142"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Sible</span>  <span class="cit-name-given-names">AM</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Nawarskas</span>  <span class="cit-name-given-names">JJ</span></span></li></ol><cite>. <span class="cit-article-title">Cangrelor: a new route for P2Y12 inhibition</span>. <abbr class="cit-jnl-abbrev">Cardiol Rev</abbr> <span class="cit-pub-date">2017</span>;<span class="cit-vol">25</span>:<span class="cit-fpage">133</span>–<span class="cit-lpage">39</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1097/CRD.0000000000000142</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>28379902</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1097/CRD.0000000000000142&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=28379902&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">18.</span><a class="rev-xref-ref" href="#xref-ref-18-1" title="View reference 18. in text" id="ref-18">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.18" data-doi="10.3174/ajnr.A5759"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Kaesmacher</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Gralla</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Mosimann</span>  <span class="cit-name-given-names">PJ</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Reasons for reperfusion failures in stent-retriever-based thrombectomy: registry analysis and proposal of a classification system</span>. <abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2018</span>;<span class="cit-vol">39</span>:<span class="cit-fpage">1848</span>–<span class="cit-lpage">53</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3174/ajnr.A5759</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>30166434</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czoxMDoiMzkvMTAvMTg0OCI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci80My8zLzQxMC5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">19.</span><a class="rev-xref-ref" href="#xref-ref-19-1" title="View reference 19. in text" id="ref-19">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.19" data-doi="10.5853/jos.2017.00283"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Kim</span>  <span class="cit-name-given-names">BM</span></span></li></ol><cite>. <span class="cit-article-title">Causes and solutions of endovascular treatment failure</span>. <abbr class="cit-jnl-abbrev">J Stroke</abbr> <span class="cit-pub-date">2017</span>;<span class="cit-vol">19</span>:<span class="cit-fpage">131</span>–<span class="cit-lpage">42</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.5853/jos.2017.00283</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>28592777</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.5853/jos.2017.00283&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=http://www.n&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">20.</span><a class="rev-xref-ref" href="#xref-ref-20-1" title="View reference 20. in text" id="ref-20">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.20" data-doi="10.1007/s00062-019-00777-1"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Yeo</span>  <span class="cit-name-given-names">LL</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Bhogal</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Gopinathan</span>  <span class="cit-name-given-names">A</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Why does mechanical thrombectomy in large vessel occlusion sometimes fail? A review of the literature</span>. <abbr class="cit-jnl-abbrev">Clin Neuroradiol</abbr> <span class="cit-pub-date">2019</span>;<span class="cit-vol">29</span>:<span class="cit-fpage">401</span>–<span class="cit-lpage">14</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1007/s00062-019-00777-1</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>30895349</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1007/s00062-019-00777-1&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=http://www.n&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">21.</span><a class="rev-xref-ref" href="#xref-ref-21-1" title="View reference 21. in text" id="ref-21">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.21" data-doi="10.3174/ajnr.A7180"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Marnat</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Delvoye</span>  <span class="cit-name-given-names">F</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Finitsis</span>  <span class="cit-name-given-names">S</span></span>, <span class="cit-etal">et al</span></li></ol><cite>; <span class="cit-auth cit-collab">ETIS Investigators</span>. <span class="cit-article-title">A multicenter preliminary study of cangrelor following thrombectomy failure for refractory proximal intracranial occlusions</span>. <abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">42</span>:<span class="cit-fpage">1452</span>–<span class="cit-lpage">57</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3174/ajnr.A7180</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>34117019</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiI0Mi84LzE0NTIiO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvNDMvMy80MTAuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">22.</span><a class="rev-xref-ref" href="#xref-ref-22-1" title="View reference 22. in text" id="ref-22">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.22" data-doi="10.1016/j.wneu.2019.08.192"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Maingard</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Phan</span>  <span class="cit-name-given-names">K</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Lamanna</span>  <span class="cit-name-given-names">A</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Rescue intracranial stenting after failed mechanical thrombectomy for acute ischemic stroke: a systematic review and meta-analysis</span>. <abbr class="cit-jnl-abbrev">World Neurosurg</abbr> <span class="cit-pub-date">2019</span>;<span class="cit-vol">132</span>:<span class="cit-fpage">e235</span>–<span class="cit-lpage">45</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/j.wneu.2019.08.192</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31493593</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.wneu.2019.08.192&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31493593&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">23.</span><a class="rev-xref-ref" href="#xref-ref-23-1" title="View reference 23. in text" id="ref-23">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.23" data-doi="10.1016/j.jstrokecerebrovasdis.2020.105521"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Delvoye</span>  <span class="cit-name-given-names">F</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Maier</span>  <span class="cit-name-given-names">B</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Escalard</span>  <span class="cit-name-given-names">S</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Antiplatelet therapy during emergent extracranial internal carotid artery stenting: comparison of three intravenous antiplatelet perioperative strategies</span>. <abbr class="cit-jnl-abbrev">J Stroke Cerebrovasc Dis</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">30</span>:<span class="cit-fpage">105521</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/j.jstrokecerebrovasdis.2020.105521</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>33310073</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.jstrokecerebrovasdis.2020.105521&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=http://www.n&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">24.</span><a class="rev-xref-ref" href="#xref-ref-24-1" title="View reference 24. in text" id="ref-24">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.24" data-doi="10.1161/STROKEAHA.119.027977"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Boisseau</span>  <span class="cit-name-given-names">W</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Fahed</span>  <span class="cit-name-given-names">R</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Lapergue</span>  <span class="cit-name-given-names">B</span></span>, <span class="cit-etal">et al</span></li></ol><cite>; <span class="cit-auth cit-collab">ETIS Investigators</span>. <span class="cit-article-title">Predictors of parenchymal hematoma after mechanical thrombectomy: a multicenter study</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2020</span>;<span class="cit-vol">51</span>:<span class="cit-fpage">2364</span>–<span class="cit-lpage">70</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.119.027977</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31670928</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1161/STROKEAHA.119.027977&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31670928&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">25.</span><a class="rev-xref-ref" href="#xref-ref-25-1" title="View reference 25. in text" id="ref-25">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.25" data-doi="10.1161/STROKEAHA.116.016368"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Hao</span>  <span class="cit-name-given-names">Y</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Yang</span>  <span class="cit-name-given-names">D</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Wang</span>  <span class="cit-name-given-names">H</span></span>, <span class="cit-etal">et al</span></li></ol><cite>; <span class="cit-auth cit-collab">ACTUAL Investigators (Endovascular Treatment for Acute Anterior Circulation Ischemic Stroke Registry)</span>. <span class="cit-article-title">Predictors for symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2017</span>;<span class="cit-vol">48</span>:<span class="cit-fpage">1203</span>–<span class="cit-lpage">09</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.116.016368</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>28373302</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6OToic3Ryb2tlYWhhIjtzOjU6InJlc2lkIjtzOjk6IjQ4LzUvMTIwMyI7czo0OiJhdG9tIjtzOjE5OiIvYWpuci80My8zLzQxMC5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30=" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">26.</span><a class="rev-xref-ref" href="#xref-ref-26-1" title="View reference 26. in text" id="ref-26">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.26" data-doi="10.1002/phar.2619"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Holden</span>  <span class="cit-name-given-names">DN</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Entezami</span>  <span class="cit-name-given-names">P</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Bush</span>  <span class="cit-name-given-names">MC</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Characterization of antiplatelet response to low-dose cangrelor utilizing platelet function testing in neuroendovascular patients</span>. <abbr class="cit-jnl-abbrev">Pharmacotherapy</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">41</span>:<span class="cit-fpage">811</span>–<span class="cit-lpage">19</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1002/phar.2619</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>34496076</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1002/phar.2619&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=34496076&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">27.</span><a class="rev-xref-ref" href="#xref-ref-27-1" title="View reference 27. in text" id="ref-27">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.27" data-doi="10.1016/j.bja.2019.03.019"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Godier</span>  <span class="cit-name-given-names">A</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Mesnil</span>  <span class="cit-name-given-names">M</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">De Mesmay</span>  <span class="cit-name-given-names">M</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Bridging antiplatelet therapy with cangrelor in patients with recent intracranial stenting undergoing invasive procedures: a prospective case series</span>. <abbr class="cit-jnl-abbrev">Br J Anaesth</abbr> <span class="cit-pub-date">2019</span>;<span class="cit-vol">123</span>:<span class="cit-fpage">e2</span>–<span class="cit-lpage">e5</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1016/j.bja.2019.03.019</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31010645</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1016/j.bja.2019.03.019&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31010645&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li><li><span class="ref-label">28.</span><a class="rev-xref-ref" href="#xref-ref-28-1" title="View reference 28. in text" id="ref-28">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.28" data-doi="10.3174/ajnr.A7124"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Abdalla</span>  <span class="cit-name-given-names">RN</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Cantrell</span>  <span class="cit-name-given-names">DR</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Shaibani</span>  <span class="cit-name-given-names">A</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Refractory stroke thrombectomy: prevalence, etiology, and adjunctive treatment in a North American cohort</span><abbr class="cit-jnl-abbrev">. AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2021</span>;<span class="cit-vol">42</span>:<span class="cit-fpage">1258</span>–<span class="cit-lpage">63</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3174/ajnr.A7124</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>33888454</span></cite></div><div class="cit-extra"><a href="/lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6NDoiYWpuciI7czo1OiJyZXNpZCI7czo5OiI0Mi83LzEyNTgiO3M6NDoiYXRvbSI7czoxOToiL2FqbnIvNDMvMy80MTAuYXRvbSI7fXM6ODoiZnJhZ21lbnQiO3M6MDoiIjt9" class="cit-ref-sprinkles cit-ref-sprinkles-ijlink"><span><span class="cit-reflinks-abstract">Abstract</span><span class="cit-sep cit-reflinks-variant-name-sep">/</span><span class="cit-reflinks-full-text"><span class="free-full-text">FREE </span>Full Text</span></span></a></div></div></li><li><span class="ref-label">29.</span><a class="rev-xref-ref" href="#xref-ref-29-1" title="View reference 29. in text" id="ref-29">↵</a><div class="cit ref-cit ref-journal" id="cit-43.3.410.29" data-doi="10.1161/STROKEAHA.119.024889"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Tsang</span>  <span class="cit-name-given-names">AC</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Orru</span>  <span class="cit-name-given-names">E</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Klostranec</span>  <span class="cit-name-given-names">JM</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Thrombectomy outcomes of intracranial atherosclerosis-related occlusions</span>. <abbr class="cit-jnl-abbrev">Stroke</abbr> <span class="cit-pub-date">2019</span>;<span class="cit-vol">50</span>:<span class="cit-fpage">1460</span>–<span class="cit-lpage">66</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.1161/STROKEAHA.119.024889</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>31084327</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.1161/STROKEAHA.119.024889&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=31084327&amp;link_type=MED&amp;atom=%2Fajnr%2F43%2F3%2F410.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li></ol></div></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 43</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 3 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Mar 2022 </div></div>
      
      
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      <div class="highwire-cite-title">Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis</div>  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Mar 2022, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">410-415; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7430 </span></div>
  
  
  
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      <div class="highwire-cite-title">Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Marnat</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Finistis</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Delvoye</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">I.</span> <span class="nlm-surname">Sibon</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.-P.</span> <span class="nlm-surname">Desilles</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Mazighi</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Gariel</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Consoli</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Rosso</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Clarençon</span></span>, <span class="highwire-citation-author" data-delta="10"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Elhorany</span></span>, <span class="highwire-citation-author" data-delta="11"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Denier</span></span>, <span class="highwire-citation-author" data-delta="12"><span class="nlm-given-names">V.</span> <span class="nlm-surname">Chalumeau</span></span>, <span class="highwire-citation-author" data-delta="13"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Caroff</span></span>, <span class="highwire-citation-author" data-delta="14"><span class="nlm-given-names">L.</span> <span class="nlm-surname">Veunac</span></span>, <span class="highwire-citation-author" data-delta="15"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Bourdain</span></span>, <span class="highwire-citation-author" data-delta="16"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Darcourt</span></span>, <span class="highwire-citation-author" data-delta="17"><span class="nlm-given-names">J.-M.</span> <span class="nlm-surname">Olivot</span></span>, <span class="highwire-citation-author" data-delta="18"><span class="nlm-given-names">R.</span> <span class="nlm-surname">Bourcier</span></span>, <span class="highwire-citation-author" data-delta="19"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Dargazanli</span></span>, <span class="highwire-citation-author" data-delta="20"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Arquizan</span></span>, <span class="highwire-citation-author" data-delta="21"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Richard</span></span>, <span class="highwire-citation-author" data-delta="22"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Lapergue</span></span>, <span class="highwire-citation-author" data-delta="23"><span class="nlm-given-names">B.</span> <span class="nlm-surname">Gory</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Mar 2022, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">410-415; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7430 </span></div>
  
  
  
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