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<meta name="DC.Title" content="RAPID CT Perfusion–Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke" />
<meta name="DC.Identifier" content="10.3174/ajnr.A7542" />
<meta name="DC.Date" content="2022-07-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Information of collateral flow may help to determine eligibility for thrombectomy. Our aim was to identify CT perfusion–based surrogate parameters of good collateral status in acute anterior circulation ischemic stroke.

MATERIALS AND METHODS: In this retrospective study, we assessed the collateral status of 214 patients who presented with acute ischemic stroke due to occlusion of the MCA M1 segment or the carotid terminus. Collaterals were assessed on dynamic CTA images analogous to the multiphase CTA score by Menon et al. CT perfusion parameters (time-to-maximum, relative CBF, hypoperfusion intensity ratio, and CBV-index) were assessed with RAPID software. The Spearman rank correlation and receiver operating characteristic analyses were performed to identify the parameters that correlate with collateral scores and good collateral supply (defined as a collateral score of ≥4).

RESULTS: The Spearman rank correlation was highest for a relative CBF &lt; 38% volume (ρ = −0.66, P  &lt; .001), followed by the hypoperfusion intensity ratio (ρ = −0.49, P  &lt; .001), CBV-index (ρ = 0.51, P  &lt; .001), and time-to-maximum &gt; 8 seconds (ρ = −0.54, P  &lt; .001). Good collateral status was better identified by a relative CBF &lt; 38% at a lesion size &lt;27 mL (sensitivity of 75%, specificity of 80%) compared with a hypoperfusion intensity ratio of &lt;0.4 (sensitivity of 75%, specificity of 62%), CBV-index of &gt;0.8 (sensitivity of 60%, specificity of 78%), and time-to-maximum &gt; 8 seconds (sensitivity of 68%, specificity of 76%).

CONCLUSIONS: Automated CT perfusion analysis allows accurate identification of collateral status in acute ischemic stroke. A relative CBF &lt; 38% may be a better perfusion-based indicator of good collateral supply compared with time-to-maximum, the hypoperfusion intensity ratio, and the CBV-index.

AUC
:   area under the curve
HIR
:   hypoperfusion intensity ratio
IQR
:   interquartile range
mCTA
:   multiphase CTA
rCBF
:   relative CBF
sCTA
:   single-phase CTA
Tmax
:   time-to-maximum" />
<meta name="DC.Contributor" content="A. Potreck" />
<meta name="DC.Contributor" content="E. Scheidecker" />
<meta name="DC.Contributor" content="C.S. Weyland" />
<meta name="DC.Contributor" content="U. Neuberger" />
<meta name="DC.Contributor" content="C. Herweh" />
<meta name="DC.Contributor" content="M.A. Möhlenbruch" />
<meta name="DC.Contributor" content="M. Chen" />
<meta name="DC.Contributor" content="S. Nagel" />
<meta name="DC.Contributor" content="M. Bendszus" />
<meta name="DC.Contributor" content="F. Seker" />
<meta name="article:published_time" content="2022-07-01" />
<meta name="citation_title" content="RAPID CT Perfusion–Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Information of collateral flow may help to determine eligibility for thrombectomy. Our aim was to identify CT perfusion–based surrogate parameters of good collateral status in acute anterior circulation ischemic stroke.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;In this retrospective study, we assessed the collateral status of 214 patients who presented with acute ischemic stroke due to occlusion of the MCA M1 segment or the carotid terminus. Collaterals were assessed on dynamic CTA images analogous to the multiphase CTA score by Menon et al. CT perfusion parameters (time-to-maximum, relative CBF, hypoperfusion intensity ratio, and CBV-index) were assessed with RAPID software. The Spearman rank correlation and receiver operating characteristic analyses were performed to identify the parameters that correlate with collateral scores and good collateral supply (defined as a collateral score of ≥4).&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;The Spearman rank correlation was highest for a relative CBF &amp;lt; 38% volume (ρ = −0.66, &lt;i&gt;P &lt;/i&gt;&amp;lt; .001), followed by the hypoperfusion intensity ratio (ρ = −0.49, &lt;i&gt;P &lt;/i&gt;&amp;lt; .001), CBV-index (ρ = 0.51, &lt;i&gt;P &lt;/i&gt;&amp;lt; .001), and time-to-maximum &amp;gt; 8 seconds (ρ = −0.54, &lt;i&gt;P &lt;/i&gt;&amp;lt; .001). Good collateral status was better identified by a relative CBF &amp;lt; 38% at a lesion size &amp;lt;27 mL (sensitivity of 75%, specificity of 80%) compared with a hypoperfusion intensity ratio of &amp;lt;0.4 (sensitivity of 75%, specificity of 62%), CBV-index of &amp;gt;0.8 (sensitivity of 60%, specificity of 78%), and time-to-maximum &amp;gt; 8 seconds (sensitivity of 68%, specificity of 76%).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Automated CT perfusion analysis allows accurate identification of collateral status in acute ischemic stroke. A relative CBF &amp;lt; 38% may be a better perfusion-based indicator of good collateral supply compared with time-to-maximum, the hypoperfusion intensity ratio, and the CBV-index.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="2022/07/01" />
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<meta name="citation_issn" content="0195-6108" />
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<meta name="citation_firstpage" content="960" />
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<meta name="citation_author" content="A. Potreck" />
<meta name="citation_author_institution" content="aFrom the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)" />
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<meta name="citation_author" content="E. Scheidecker" />
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<meta name="citation_author" content="C.S. Weyland" />
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<meta name="citation_reference" content="citation_journal_title=Stroke;citation_author=DEFUSE 2 Investigators;citation_title=Hypoperfusion intensity ratio predicts infarct progression and functional outcome in the DEFUSE 2 cohort;citation_volume=45;citation_year=2014;citation_pmid=24595591;citation_doi=10.1161/STROKEAHA.113.003857" />
<meta name="citation_reference" content="citation_journal_title=Ann Neurol;citation_author=A. Guenego;citation_author=M. Mlynash;citation_author=S. Christensen;citation_title=Hypoperfusion ratio predicts infarct growth during transfer for thrombectomy;citation_pages=616-20;citation_volume=84;citation_year=2018;citation_pmid=30168180;citation_doi=10.1002/ana.25320" />
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<meta name="twitter:title" content="RAPID CT Perfusion–Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Information of collateral flow may help to determine eligibility for thrombectomy. Our aim was to identify CT perfusion–based surrogate parameters of good collateral status in acute anterior circulation ischemic stroke.

MATERIALS AND METHODS: In this retrospective study, we assessed the collateral status of 214 patients who presented with acute ischemic stroke due to occlusion of the MCA M1 segment or the carotid terminus. Collaterals were assessed on dynamic CTA images analogous to the multiphase CTA score by Menon et al. CT perfusion parameters (time-to-maximum, relative CBF, hypoperfusion intensity ratio, and CBV-index) were assessed with RAPID software. The Spearman rank correlation and receiver operating characteristic analyses were performed to identify the parameters that correlate with collateral scores and good collateral supply (defined as a collateral score of ≥4).

RESULTS: The Spearman rank correlation was highest for a relative CBF &lt; 38% volume (ρ = −0.66, P  &lt; .001), followed by the hypoperfusion intensity ratio (ρ = −0.49, P  &lt; .001), CBV-index (ρ = 0.51, P  &lt; .001), and time-to-maximum &gt; 8 seconds (ρ = −0.54, P  &lt; .001). Good collateral status was better identified by a relative CBF &lt; 38% at a lesion size &lt;27 mL (sensitivity of 75%, specificity of 80%) compared with a hypoperfusion intensity ratio of &lt;0.4 (sensitivity of 75%, specificity of 62%), CBV-index of &gt;0.8 (sensitivity of 60%, specificity of 78%), and time-to-maximum &gt; 8 seconds (sensitivity of 68%, specificity of 76%).

CONCLUSIONS: Automated CT perfusion analysis allows accurate identification of collateral status in acute ischemic stroke. A relative CBF &lt; 38% may be a better perfusion-based indicator of good collateral supply compared with time-to-maximum, the hypoperfusion intensity ratio, and the CBV-index.

AUC
:   area under the curve
HIR
:   hypoperfusion intensity ratio
IQR
:   interquartile range
mCTA
:   multiphase CTA
rCBF
:   relative CBF
sCTA
:   single-phase CTA
Tmax
:   time-to-maximum" />
<meta name="og-title" property="og:title" content="RAPID CT Perfusion–Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/43/7/960" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Information of collateral flow may help to determine eligibility for thrombectomy. Our aim was to identify CT perfusion–based surrogate parameters of good collateral status in acute anterior circulation ischemic stroke.

MATERIALS AND METHODS: In this retrospective study, we assessed the collateral status of 214 patients who presented with acute ischemic stroke due to occlusion of the MCA M1 segment or the carotid terminus. Collaterals were assessed on dynamic CTA images analogous to the multiphase CTA score by Menon et al. CT perfusion parameters (time-to-maximum, relative CBF, hypoperfusion intensity ratio, and CBV-index) were assessed with RAPID software. The Spearman rank correlation and receiver operating characteristic analyses were performed to identify the parameters that correlate with collateral scores and good collateral supply (defined as a collateral score of ≥4).

RESULTS: The Spearman rank correlation was highest for a relative CBF &lt; 38% volume (ρ = −0.66, P  &lt; .001), followed by the hypoperfusion intensity ratio (ρ = −0.49, P  &lt; .001), CBV-index (ρ = 0.51, P  &lt; .001), and time-to-maximum &gt; 8 seconds (ρ = −0.54, P  &lt; .001). Good collateral status was better identified by a relative CBF &lt; 38% at a lesion size &lt;27 mL (sensitivity of 75%, specificity of 80%) compared with a hypoperfusion intensity ratio of &lt;0.4 (sensitivity of 75%, specificity of 62%), CBV-index of &gt;0.8 (sensitivity of 60%, specificity of 78%), and time-to-maximum &gt; 8 seconds (sensitivity of 68%, specificity of 76%).

CONCLUSIONS: Automated CT perfusion analysis allows accurate identification of collateral status in acute ischemic stroke. A relative CBF &lt; 38% may be a better perfusion-based indicator of good collateral supply compared with time-to-maximum, the hypoperfusion intensity ratio, and the CBV-index.

AUC
:   area under the curve
HIR
:   hypoperfusion intensity ratio
IQR
:   interquartile range
mCTA
:   multiphase CTA
rCBF
:   relative CBF
sCTA
:   single-phase CTA
Tmax
:   time-to-maximum" />
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      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">RAPID CT Perfusion–Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">A. Potreck</span>, <span class="highwire-citation-author" data-delta="1">E. Scheidecker</span>, <span class="highwire-citation-author" data-delta="2">C.S. Weyland</span>, <span class="highwire-citation-author" data-delta="3">U. Neuberger</span>, <span class="highwire-citation-author" data-delta="4">C. Herweh</span>, <span class="highwire-citation-author" data-delta="5">M.A. Möhlenbruch</span>, <span class="highwire-citation-author" data-delta="6">M. Chen</span>, <span class="highwire-citation-author" data-delta="7">S. Nagel</span>, <span class="highwire-citation-author" data-delta="8">M. Bendszus</span> and <span class="highwire-citation-author" data-delta="9">F. Seker</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">July 2022,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">960-965; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A7542 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-97871--6279898210" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">A. Potreck </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BPotreck%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Potreck%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AA.%2BPotreck%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-9206-2636" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for A. Potreck</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">E. Scheidecker </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=E.%2BScheidecker%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Scheidecker%20E&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AE.%2BScheidecker%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">C.S. Weyland </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.S.%2BWeyland%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Weyland%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.S.%2BWeyland%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-1374-7854" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C.S. Weyland</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">U. Neuberger </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=U.%2BNeuberger%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Neuberger%20U&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AU.%2BNeuberger%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-3085-3886" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for U. Neuberger</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">C. Herweh </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C.%2BHerweh%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Herweh%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AC.%2BHerweh%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-9223-9662" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for C. Herweh</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">M.A. Möhlenbruch </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.A.%2BM%C3%B6hlenbruch%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=M%C3%B6hlenbruch%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.A.%2BM%25C3%25B6hlenbruch%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-5075-704X" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M.A. Möhlenbruch</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">M. Chen </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Neurology (M.C., S.N.), Heidelberg University Hospital, Heidelberg, Germany</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BChen%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chen%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BChen%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-9079-9298" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. Chen</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">S. Nagel </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Neurology (M.C., S.N.), Heidelberg University Hospital, Heidelberg, Germany</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BNagel%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Nagel%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AS.%2BNagel%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0003-2471-6647" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for S. 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Bendszus </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Departments of Neuroradiology (A.P., E.S., C.S.W., U.N., C.H., M.A.M., M.B., F.S.)</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BBendszus%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Bendszus%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AM.%2BBendszus%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-9094-6769" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for M. 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 43</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 7 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jul 2022 </div></div>
      
      
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      <div class="highwire-cite-title">RAPID CT Perfusion for Collateral Status in Stroke</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Potreck</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">E.</span> <span class="nlm-surname">Scheidecker</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">C.S.</span> <span class="nlm-surname">Weyland</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">U.</span> <span class="nlm-surname">Neuberger</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Herweh</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">M.A.</span> <span class="nlm-surname">Möhlenbruch</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Chen</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Nagel</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Bendszus</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Seker</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jul 2022, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">960-965; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7542 </span></div>
  
  
  
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      <div class="highwire-cite-title">RAPID CT Perfusion for Collateral Status in Stroke</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">A.</span> <span class="nlm-surname">Potreck</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">E.</span> <span class="nlm-surname">Scheidecker</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">C.S.</span> <span class="nlm-surname">Weyland</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">U.</span> <span class="nlm-surname">Neuberger</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">C.</span> <span class="nlm-surname">Herweh</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">M.A.</span> <span class="nlm-surname">Möhlenbruch</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Chen</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Nagel</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Bendszus</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">F.</span> <span class="nlm-surname">Seker</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jul 2022, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">43 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">960-965; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A7542 </span></div>
  
  
  
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