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<meta name="DC.Title" content="ACCESS: ACtive Catheterization for EndovaScular TreatmentS—A First-in-Human, Single-Center, Nonrandomized, Open Clinical Study of the G60 Active Device for Endovascular Neurointerventions" />
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<meta name="DC.Description" content="SUMMARY: The catheterization of supra-aortic vessels during neuroendovascular interventions may be challenging in the setting of complex aortic arch anatomy. Evaluation of a new mechatronic controllable directional device in conjunction with different sheath and guide catheters to ease the cannulation of the supra-aortic vessels was conducted in the setting of a first-in-human clinical study. The evaluation assessment included access to the aortic arch, the technical success of the device in terms of time to target vessel, target vessel catheterization, adverse events, and clinical outcome. Ten subjects were enrolled at 1 site for treatment. Successful access, target vessel catheterization, and correct positioning of the catheter into the target vessel with the G60 device were achieved for all 10 procedures (7 from femoral access, 3 from radial access). One procedural complication, unrelated to the G60 device, was recorded during the investigation. The G60 is a polyvalent active device that facilitates guide catheter navigation in neuroendovascular interventions.

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<meta name="DC.Contributor" content="Simon Escalard" />
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&lt;p&gt;The catheterization of supra-aortic vessels during neuroendovascular interventions may be challenging in the setting of complex aortic arch anatomy. Evaluation of a new mechatronic controllable directional device in conjunction with different sheath and guide catheters to ease the cannulation of the supra-aortic vessels was conducted in the setting of a first-in-human clinical study. The evaluation assessment included access to the aortic arch, the technical success of the device in terms of time to target vessel, target vessel catheterization, adverse events, and clinical outcome. Ten subjects were enrolled at 1 site for treatment. Successful access, target vessel catheterization, and correct positioning of the catheter into the target vessel with the G60 device were achieved for all 10 procedures (7 from femoral access, 3 from radial access). One procedural complication, unrelated to the G60 device, was recorded during the investigation. The G60 is a polyvalent active device that facilitates guide catheter navigation in neuroendovascular interventions.&lt;/p&gt;" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node110803--7" data-node-nid="110803" id="top-node-110803--81119479624" data-pisa="ajnr;45/10/1495" data-pisa-master="ajnr;ajnr.A8345" data-apath="/ajnr/45/10/1495.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Brief Report</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Neurointervention</span></span></div>
  
      <div class="highwire-cite-access"><span class="highwire-citation-access"><i class="highwire-access-icon highwire-access-icon-open-access open-access hw-icon-open-access" title="Open Access" aria-hidden="true"></i><span  class="element-invisible highwire-access-icon highwire-access-icon-open-access" style="">Open Access</span></span></div>
  
      <h1 class="highwire-cite-title" id="page-title">ACCESS: ACtive Catheterization for EndovaScular TreatmentS—A First-in-Human, Single-Center, Nonrandomized, Open Clinical Study of the G60 Active Device for Endovascular Neurointerventions</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Simon Escalard</span>, <span class="highwire-citation-author" data-delta="1">Amira Al-Raaisi</span>, <span class="highwire-citation-author" data-delta="2">Jean-Philippe Désilles</span>, <span class="highwire-citation-author" data-delta="3">Hocine Redjem</span>, <span class="highwire-citation-author" data-delta="4">Stanislas Smajda</span>, <span class="highwire-citation-author" data-delta="5">Mounir Lahlouh</span>, <span class="highwire-citation-author" data-delta="6">François Delvoye</span>, <span class="highwire-citation-author" data-delta="7">William Boisseau</span>, <span class="highwire-citation-author" data-delta="8">Mikaël Mazighi</span> and <span class="highwire-citation-author" data-delta="9">Michel Piotin</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">October 2024,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1495-1498; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A8345 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-110803--81119479624" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Simon Escalard </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Simon%2BEscalard%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Escalard%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this 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class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Jean-Philippe%2BD%C3%A9silles%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=D%C3%A9silles%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJean-Philippe%2BD%25C3%25A9silles%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8395-6312" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Jean-Philippe Désilles</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Hocine Redjem </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Hocine%2BRedjem%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Redjem%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AHocine%2BRedjem%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6943-9922" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Hocine Redjem</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Stanislas Smajda </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Stanislas%2BSmajda%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Smajda%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AStanislas%2BSmajda%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-6486-1710" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Stanislas Smajda</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">Mounir Lahlouh </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>CREsTIC (M.L.), Université de Reims, Reims, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Mounir%2BLahlouh%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Lahlouh%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMounir%2BLahlouh%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">François Delvoye </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Fran%C3%A7ois%2BDelvoye%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Delvoye%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AFran%25C3%25A7ois%2BDelvoye%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-0697-2156" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for François Delvoye</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">William Boisseau </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=William%2BBoisseau%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Boisseau%20W&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AWilliam%2BBoisseau%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0001-8120-5128" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for William Boisseau</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">Mikaël Mazighi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>From the Department of Interventional Neuroradiology (S.E., J.-P.D., H.R., S.S., F.D., W.B., A.A.-R., M.M., M.P.), Rothschild Foundation Hospital, Paris, France</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Mika%C3%ABl%2BMazighi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mazighi%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMika%25C3%25ABl%2BMazighi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on 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href="/lookup/external-ref?access_num=Piotin%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AMichel%2BPiotin%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="https://orcid.org/0000-0002-1354-4328" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Michel Piotin</a></li></ul></div></div></div>  </div>

  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">vol. 45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">no. 10 </span><span  class="highwire-cite-metadata-page-string highwire-cite-metadata">1495-1498 </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Simon</span> <span class="nlm-surname">Escalard</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Amira</span> <span class="nlm-surname">Al-Raaisi</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Jean-Philippe</span> <span class="nlm-surname">Désilles</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Hocine</span> <span class="nlm-surname">Redjem</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Stanislas</span> <span class="nlm-surname">Smajda</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Mounir</span> <span class="nlm-surname">Lahlouh</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">François</span> <span class="nlm-surname">Delvoye</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">William</span> <span class="nlm-surname">Boisseau</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Mikaël</span> <span class="nlm-surname">Mazighi</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Michel</span> <span class="nlm-surname">Piotin</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1495-1498; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8345 </span></div>
  
  
  
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      <div class="highwire-cite-title">ACCESS: ACtive Catheterization for EndovaScular TreatmentS—A First-in-Human, Single-Center, Nonrandomized, Open Clinical Study of the G60 Active Device for Endovascular Neurointerventions</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Simon</span> <span class="nlm-surname">Escalard</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Amira</span> <span class="nlm-surname">Al-Raaisi</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Jean-Philippe</span> <span class="nlm-surname">Désilles</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Hocine</span> <span class="nlm-surname">Redjem</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Stanislas</span> <span class="nlm-surname">Smajda</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Mounir</span> <span class="nlm-surname">Lahlouh</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">François</span> <span class="nlm-surname">Delvoye</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">William</span> <span class="nlm-surname">Boisseau</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Mikaël</span> <span class="nlm-surname">Mazighi</span></span>, <span class="highwire-citation-author" data-delta="9"><span class="nlm-given-names">Michel</span> <span class="nlm-surname">Piotin</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-oa-ind highwire-cite-metadata"><i class="highwire-oa-indicator"></i> </span><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2024, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">45 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1495-1498; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8345 </span></div>
  
  
  
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