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      Volumetric Assessment of Optic Nerve Sheath and Hypophysis in Idiopathic Intracranial Hypertension  
    	J. Hoffmann, C. Schmidt, H. Kunte, R. Klingebiel, L. Harms, H.-J. Huppertz, L. Lüdemann and E. Wiener
  
    	American Journal of Neuroradiology March 2014, 35 (3) 513-518; DOI: https://doi.org/10.3174/ajnr.A3694 
  
  
  


  
  
      EDITOR'S CHOICEBrain 
  
      Open Access
  
      Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T  
    	H. Guo, X. Song, R. Vandorpe, Y. Zhang, W. Chen, N. Zhang, M.H. Schmidt and K. Rockwood for the Alzheimer's Disease Neuroimaging Initiative
  
    	American Journal of Neuroradiology March 2014, 35 (3) 504-512; DOI: https://doi.org/10.3174/ajnr.A3709 
  
    	This study assesses the usefulness of a set of established structural findings in Alzheimer disease with various MRI sequences at 2 different field strengths in 127 subjects. Scores of atrophy and lesion burden were reliable across sequences and unit strength and were lowest in individuals with cognitive impairment, higher in those with Alzheimer disease, and also correlated with age, cognitive performance, and amyloid-β test. Although the results were slightly better at 3T, the authors concluded that even at 1.5T scores were reliable.
  
  


  
  
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      Subcortical Cystic Lesions within the Anterior Superior Temporal Gyrus: A Newly Recognized Characteristic Location for Dilated Perivascular Spaces  
    	S. Rawal, S.E. Croul, R.A. Willinsky, M. Tymianski and T. Krings
  
    	American Journal of Neuroradiology February 2014, 35 (2) 317-322; DOI: https://doi.org/10.3174/ajnr.A3669 
  
    	Fifteen patients with unusual dilated perivascular spaces in the subcortical white matter of the anterior superior temporal gyrus were presented. In one, pathology showed gliosis and innumerable perivascular spaces. Findings that suggest cysts in this location were perivascular spaces include: lack of symptoms, proximity to the subarachnoid space, adjacent blood vessels, and stability over time.
  
  


  
  
      Brain 
  
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      Frontotemporal Cortical Thinning in Amyotrophic Lateral Sclerosis  
    	A. d'Ambrosio, A. Gallo, F. Trojsi, D. Corbo, F. Esposito, M. Cirillo, M.R. Monsurrò and G. Tedeschi
  
    	American Journal of Neuroradiology February 2014, 35 (2) 304-310; DOI: https://doi.org/10.3174/ajnr.A3753 
  
  
  


  
  
      EDITOR'S CHOICEBrain 
  
      Open Access
  
      Use of FLAIR Imaging to Identify Onset Time of Cerebral Ischemia in a Canine Model  
    	X.-Q. Xu, Q.-Q. Zu, S.-S. Lu, Q.-G. Cheng, J. Yu, Y. Sheng, H.-B. Shi and S. Liu
  
    	American Journal of Neuroradiology February 2014, 35 (2) 311-316; DOI: https://doi.org/10.3174/ajnr.A3689 
  
    	After an infarction-inducing procedure, 20 dogs were imaged at 3, 4, 5, 6, and 24 hours with FLAIR and DWI. A mismatch between the 2 sequences (positive DWI and negative FLAIR) was found to reliably predict the time of infarct onset. By 6 hours, 95% of dogs had FLAIR abnormalities and by 24 hours all did. However, at 3 hours only 15% of dogs showed positive FLAIR studies. These results could serve as guidelines to estimate the time of onset of ischemic events.
  
  


  
  
      Brain 
  
      Open Access
  
      Local and Global Fiber Tractography in Patients with Epilepsy  
    	C. Anastasopoulos, M. Reisert, V.G. Kiselev, T. Nguyen-Thanh, A. Schulze-Bonhage, J. Zentner and I. Mader
  
    	American Journal of Neuroradiology February 2014, 35 (2) 291-296; DOI: https://doi.org/10.3174/ajnr.A3752 
  
  
  


  
  
      Brain 
  
      Open Access
  
      ⁶²Cu-Diacetyl-Bis (N⁴-Methylthiosemicarbazone) PET in Human Gliomas: Comparative Study with [¹⁸F]Fluorodeoxyglucose and L-Methyl-[¹¹C]Methionine PET  
    	K. Tateishi, U. Tateishi, S. Nakanowatari, M. Ohtake, R. Minamimoto, J. Suenaga, H. Murata, K. Kubota, T. Inoue and N. Kawahara
  
    	American Journal of Neuroradiology February 2014, 35 (2) 278-284; DOI: https://doi.org/10.3174/ajnr.A3679 
  
  
  


  
  
      EDITOR'S CHOICEBrain 
  
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      Diffusion Measures Indicate Fight Exposure–Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters  
    	W. Shin, S.Y. Mahmoud, K. Sakaie, S.J. Banks, M.J. Lowe, M. Phillips, M.T. Modic and C. Bernick
  
    	American Journal of Neuroradiology February 2014, 35 (2) 285-290; DOI: https://doi.org/10.3174/ajnr.A3676 
  
    	Boxers and mixed martial arts athletes underwent brain DTI and the results were correlated with number of fights, knockouts, age, weight, and years of education. Total knockouts in boxers increased diffusivity in the corpus callosum, cingulate, pericalcarine, precuneus, and amygdala, while in martial arts athletes only the posterior cingulate was abnormal. Thus, fight exposure but not the number of fights can be used to predict microstructural brain damage.
  
  


  
  
      FELLOWS' JOURNAL CLUBBrain 
  
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      Utility of Proton MR Spectroscopy for Differentiating Typical and Atypical Primary Central Nervous System Lymphomas from Tumefactive Demyelinating Lesions  
    	S.-S. Lu, S.J. Kim, H.S. Kim, C.G. Choi, Y.-M. Lim, E.J. Kim, D.Y. Kim and S.H. Cho
  
    	American Journal of Neuroradiology February 2014, 35 (2) 270-277; DOI: https://doi.org/10.3174/ajnr.A3677 
  
    	The utility of MRS in differentiating lymphoma from tumefactive demyelination was assessed in 44 patients with the former and 21 with the latter. A Cho/Cr over 2.58 and a high lipid/lactate peak were more common in lymphoma, therefore MRS may help in differentiating these 2 entities.
  
  


  
  
      Brain 
  
      Open Access
  
      Perfusion Measurement in Brain Gliomas with Intravoxel Incoherent Motion MRI  
    	C. Federau, R. Meuli, K. O'Brien, P. Maeder and P. Hagmann
  
    	American Journal of Neuroradiology February 2014, 35 (2) 256-262; DOI: https://doi.org/10.3174/ajnr.A3686 
  
  
  

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Print ISSN: 0195-6108 Online ISSN: 1936-959X