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    More articles from Brain
  

  
  

			
		
	
	
 	
	  
  
		
		
			
			  
  
      
  
  
    
  
  
      EDITOR'S CHOICEBrain 
  
      Open Access
  
      T1 Gadolinium Enhancement of Intracranial Atherosclerotic Plaques Associated with Symptomatic Ischemic Presentations  
    	P. Vakil, J. Vranic, M.C. Hurley, R.A. Bernstein, A.W. Korutz, A. Habib, A. Shaibani, F.H. Dehkordi, T.J. Carroll and S.A. Ansari
  
    	American Journal of Neuroradiology December 2013, 34 (12) 2252-2258; DOI: https://doi.org/10.3174/ajnr.A3606 
  
    	The degree of contrast enhancement was assessed in 22 high-grade intracranial stenoses that were either symptomatic or asymptomatic. Seventy percent of symptomatic plaques showed contrast enhancement whereas this was seen in only 8% of those that were asymptomatic. This study suggests that intracranial stenoses can be evaluated with conventional MRI protocols and that there is a strong association between plaque contrast enhancement and ischemic symptoms.
  
  


  
  
      Brain 
  
      Open Access
  
      Novel White Matter Tract Integrity Metrics Sensitive to Alzheimer Disease Progression  
    	E. Fieremans, A. Benitez, J.H. Jensen, M.F. Falangola, A. Tabesh, R.L. Deardorff, M.V.S. Spampinato, J.S. Babb, D.S. Novikov, S.H. Ferris and J.A. Helpern
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2105-2112; DOI: https://doi.org/10.3174/ajnr.A3553 
  
  
  


  
  
      Brain 
  
      Open Access
  
      Effect of Age on MRI Phase Behavior in the Subcortical Deep Gray Matter of Healthy Individuals  
    	J. Hagemeier, M.G. Dwyer, N. Bergsland, F. Schweser, C.R. Magnano, M. Heininen-Brown, D.P. Ramasamy, E. Carl, C. Kennedy, R. Melia, P. Polak, A. Deistung, J.J.G. Geurts, J.R. Reichenbach and R. Zivadinov
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2144-2151; DOI: https://doi.org/10.3174/ajnr.A3569 
  
  
  


  
  
      EDITOR'S CHOICEBrain 
  
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      Arterial Spin-Labeled Perfusion Imaging Reflects Vascular Density in Nonfunctioning Pituitary Macroadenomas  
    	N. Sakai, S. Koizumi, S. Yamashita, Y. Takehara, H. Sakahara, S. Baba, Y. Oki, H. Hiramatsu and H. Namba
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2139-2143; DOI: https://doi.org/10.3174/ajnr.A3564 
  
    	In this study, arterial spin-labeling perfusion was used as a means to assess the well-known angiogenic activity seen in pituitary macroadenomas. Eleven patients with macroadenoma were studied and their ASL results correlated with histologic total microvascular density. The authors found that routine contrast enhancement did not correlate with microvascular density but CBF did and it also correlated with hypervascularity at surgery or postoperative bleeding in 4 instances.
  
  


  
  
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      Evaluation of Parkinson Disease and Alzheimer Disease with the Use of Neuromelanin MR Imaging and ¹²³I-Metaiodobenzylguanidine Scintigraphy  
    	F. Miyoshi, T. Ogawa, S.-i. Kitao, M. Kitayama, Y. Shinohara, M. Takasugi, S. Fujii and T. Kaminou
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2113-2118; DOI: https://doi.org/10.3174/ajnr.A3567 
  
  
  


  
  
      Brain 
  
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      Regional Analysis of the Magnetization Transfer Ratio of the Brain in Mild Alzheimer Disease and Amnestic Mild Cognitive Impairment  
    	M. Mascalchi, A. Ginestroni, V. Bessi, N. Toschi, S. Padiglioni, S. Ciulli, C. Tessa, M. Giannelli, L. Bracco and S. Diciotti
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2098-2104; DOI: https://doi.org/10.3174/ajnr.A3568 
  
  
  


  
  
      FELLOWS' JOURNAL CLUBBrain 
  
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      Structural Abnormalities in Patients with Insular/Peri-insular Epilepsy: Spectrum, Frequency, and Pharmacoresistance  
    	M.-C. Chevrier, C. Bard, F. Guilbert and D.K. Nguyen
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2152-2156; DOI: https://doi.org/10.3174/ajnr.A3636 
  
    	The authors reviewed imaging studies in 48 patients with insular/peri-insular epilepsy seen during a 9-year period. They found the following types of lesions: tumors (27%), cortical malformations (21%), vascular malformations (19%), and gliosis (17%,), and normal results in 8% of subjects. Refractoriness to treatment was seen in all lesions but predominantly in patients with cortical malformations.
  
  


  
  
      EDITOR'S CHOICEBrain 
  
      Open Access
  
      Perfusion Deficits Detected by Arterial Spin-Labeling in Patients with TIA with Negative Diffusion and Vascular Imaging  
    	X.J. Qiao, N. Salamon, D.J.J. Wang, R. He, M. Linetsky, B.M. Ellingson and W.B. Pope
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2125-2130; DOI: https://doi.org/10.3174/ajnr.A3551 
  
    	The current definition of TIA calls for normal imaging including DWI. Here the authors used arterial spin-labeling perfusion to detect abnormalities in nearly 50 patients within 24 hours of symptom onset and in 36 controls. The sensitivity and specificity of ASL in TIA diagnosis was 55.8% and 90.7%, respectively, and in nearly 94% of readings abnormalities that matched the clinical neurologic deficits were identified by the 3 observers. Thus, ASL perfusion is promising in evaluating and understanding TIAs.
  
  


  
  
      Brain 
  
      Open Access
  
      Improved T2* Imaging without Increase in Scan Time: SWI Processing of 2D Gradient Echo  
    	S. Soman, S.J. Holdsworth, P.D. Barnes, J. Rosenberg, J.B. Andre, R. Bammer and K.W. Yeom
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2092-2097; DOI: https://doi.org/10.3174/ajnr.A3595 
  
  
  


  
  
      Brain 
  
      You have access
  
      Normal-Appearing White Matter Permeability Distinguishes Poor Cognitive Performance in Processing Speed and Working Memory  
    	A. Eilaghi, A. Kassner, I. Sitartchouk, P.L. Francis, R. Jakubovic, A. Feinstein and R.I. Aviv
  
    	American Journal of Neuroradiology November 2013, 34 (11) 2119-2124; DOI: https://doi.org/10.3174/ajnr.A3539 
  
  
  

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Print ISSN: 0195-6108 Online ISSN: 1936-959X